Experience of Optimization of Medical Care for Women in Menopause with Dry Eye Syndrome

2021 ◽  
pp. 31-35
Author(s):  
A.S. Obrubov ◽  
◽  
Keyword(s):  
Medical Care ◽  
Dry Eye ◽  
Combined Therapy ◽  
Combined Treatment ◽  
Low Frequency ◽  
Main Group ◽  
Dry Eye Syndrome ◽  
Control Group ◽  
Treatment Technology ◽  
Complex Preparation

Purpose. Optimization of medical care for women in menopause with dry eye syndrome from the standpoint of experimental and clinical substantiation of combined technologies. Material and methods. The studies were carried out on a group of 72 patients (144 eyes) in the postmenopausal period with dry eye syndrome. The average age of women was 54.4±3.3 years. All patients, depending on the therapy, were divided into two groups. The first group (control) consisted of 34 women (68 eyes) who received only local daily monotherapy for 20 days – instillation of low-viscosity «artificial tear» preparations HyloComod. Patients of the main group were divided into 2 subgroups and used a combined treatment technology. The first subgroup consisted of 21 patients (42 eyes), who, in addition to local daily therapy of the above drug, received a suis-organ complex preparation of estrogen-like orientation Ovarium compositum once every 3 months. The second subgroup included 17 patients (34 eyes) who received a treatment technology that included local daily therapy with artificial tears in combination with courses (once every 3 months) of exposure to the head area by a pulsed low-frequency electromagnetic field in combination with suis-organ complex preparation of estrogen-like orientation Ovarium compositum. Results. The combined treatment technology was well tolerated in all examined women. There were no complications or side effects. A significant increase in the main tear production in women of the main group made it possible to achieve a significantly more pronounced decrease in symptoms of subjective discomfort than in women in the control group. The achieved results of treatment of women in the main group persisted for 2.5–3 months, which determined the frequency of the courses of combination therapy with a frequency of twice every 6 months during the subsequent observation period. Conclusion. The course of combined therapy makes it possible to achieve significant relief of subjective manifestations of dry eye syndrome in postmenopausal women. The implementation of the therapeutic effect occurs, apparently, due to the synergism of the natural factors used, which makes it possible to significantly activate the compensatory and adaptive processes in the meibomian glands. Key words: dry eye syndrome of climacteric origin, combined treatment technology, estrogen deficiency, sex hormones.

Features of the Clinical Course and Treatment of Dry Eye Syndrome in the Setting of Chronic Conjunctivitis in the South Aral Sea Region

The Eye ◽  
2021 ◽  
Vol 23 (3) ◽  
pp. 39-45
Author(s):  
F. A. Bakhritdinova ◽  
A. K. Matkarimov ◽  
S. Sh. Mirrakhimova ◽  
Z. R. Maksudova
Keyword(s):  
Dry Eye ◽  
Main Group ◽  
Dry Eye Syndrome ◽  
Aral Sea ◽  
Control Group ◽  
Eye Drops ◽  
Long Term Effects ◽  
The South ◽  
Artificial Tear ◽  
Chronic Conjunctivitis

Background. Currently, the health status of the population in the Aral Sea region should be considered with reference to long-term effects of environmental pollution – air, soil and drinking water containing toxic salts. As per results of the analysis of primary eye diseases in the Southern Aral Sea region, it was revealed that the main cause of conjunctivitis were chemical and physical exogenous irritation factors, such as dust, smoke and exposure to salt and sand storms that create a favorable environment for infection and development of secondary Dry Eye Syndrome. Purpose. To optimize treatment of secondary Dry Eye Syndrome (DES) in patients with chronic conjunctivitis in the South Aral Sea region. Materials and Methods. The research included 62 patients (120 eyes) with chronic conjunctivitis, aged 35–62 years, who had been observed in an outpatient clinic for the last 3 years, with signs of DES. All studied patients were divided into 2 groups by random sampling after preliminary adequate antibacterial and anti-inflammatory therapy. The control group (20 patients, 40 eyes) was instilled with Tsinosol antiseptic (composition: zinc sulphate, boric acid, Aseptic) – 2 drops 3 times a day, during 30 days. Patients of the main group (42 patients, 80 eyes) were instilled with Tsinosol antiseptic (2 drops 3 times a day) and Keratrop artificial tear (AT) eye drops (composition: sodium carmellose, glycerin, levocarnitine, erythrol, firma Aseptica) – 2 drops 3 times a day, during a month. All patients underwent standard ophthalmological tests, and special tests were carried out to verify DES, including Schirmer, Norn and Jones tests. Lower lacrimal meniscus height and the severity of the conjunctival fold were also determined. Results. Studies have shown that in the main group, both subjective and objective signs of the disease significantly decreased compared with the baseline and with the respective parameters of the control group, and a significant improvement in the stability of the tear film was noted. Conclusion. To optimize the therapy of secondary DES, it is necessary to include artificial tear eye drops in the treatment regimen in general, and consider using Keratrop eye drops in particular.

Effectiveness of complex treatment of «dry eye» syndrome on the background of chronic peripheral uveitis

2021 ◽  
pp. 45-48
Author(s):  
E.B. Tatarnikova ◽  
◽  
O.I. Krivosheina ◽  
Keyword(s):  
Dry Eye ◽  
Comparison Group ◽  
Combined Treatment ◽  
Treatment Method ◽  
Main Group ◽  
Dry Eye Syndrome ◽  
Laser Coagulation ◽  
Complex Method ◽  
Comprehensive Method ◽  
Tear Production

Purpose to evaluate the effectiveness of a comprehensive method of treating dry eye syndrome against the background of chronic peripheral uveitis. Material and methods. The study was performed among 98 patients (196 eyes), who made up 2 observation groups: the main group (78 people) and comparison group (20 people). The main group was treated with a new method, the comparison group was prescribed local anti-inflammatory and tear replacement therapy. Results. Application of the combined treatment showed a significant decrease in OSDI and occurrence of changes in ocular surface (up to 100%), characteristic for the syndrome of «dry eye». The indicators of total tear production became higher up to 2 times from the initial level after the therapy. Conclusion: The use of a new complex method of treatment significantly reduces the subjective and objective manifestations of the "dry eye" syndrome, contributes to an increase in total tear production against the background of relief of inflammation on the extreme periphery of the fundus compared to traditional pharmacotherapy. Key words: dry eye syndrome, chronic peripheral uveitis, combined treatment method, laser coagulation of the extreme periphery of the retina.

scholarly journals Trehalose efficacy in dry eye syndrome treatment after phacoemulsification

2016 ◽  
Vol 9 (4) ◽  
pp. 79-89 ◽  
Author(s):  
Sergey Yu Astakhov ◽  
Natalia V Tkachenko
Keyword(s):  
Dry Eye ◽  
Main Group ◽  
Dry Eye Syndrome ◽  
Control Group ◽  
Conjunctival Hyperemia ◽  
Special Investigation ◽  
Postoperative Therapy ◽  
Treatment Tolerance ◽  
Confocal Tomography ◽  
Test Result

Purpose to estimate the efficacy of “artificial tear” preparation on the trehalose base in dry eye syndrome treatment in cataract patients after phacoemulsification.Materials and methods: in 40 patients with incipient cataract phacoemulsification with IOL implantation was performed. During 1 week, all patients received eye gel with dexpanthenol in addition to postoperative therapy. Then, all patients were divided into two groups (randomization using envelopes): in the main group, the gel was replaced by Thealoz®, in the control group, the gel was discontinued. Special investigation tests (OSDI score, TBUT test, conjunctival hyperemia, corneal confocal tomography) were performed before surgery, in one week and one month after it. Statistical analysis was performed using SAS 9.4 program.Results: all investigated parameters had significant differences with time and between groups (р < 0.001). TBUT test result decreased in one week after surgery from 7.4 ± 2.1 to 4.6 ± 1.9 sec in the main group and from 7.5 ± 2.3 to 4.4 ± 2 sec in the control group. Return to baseline results in the control group was slowed down and made 6.4 ± 2.8 sec (compared with 7.9 ± 2.4 sec in the main one). In the trehalose group, OSDI score ameliorated from 35.1 ± 8.7 (in one week) to 14.2 ± 5.3 (in one month), in the control group, from 40.1 ± 11.5 to 24.8 ± 9. Conjunctival hyperemia was also less pronounced in the main group in one month after surgery: 0.45 ± 0.6 (1.6 ± 0.7 in one week), in the control group, these indices were equal to 1.7 ± 0.5 (in one week) and 1.3 ± 0.7 (in one month).Conclusions: Thealoz® use as a part of combined postoperative therapy helps to effectively fight against dry eye syndrome main signs and enhances treatment tolerance.

Dry Eye Syndrome-Related Quality of Life in Glaucoma Patients

2009 ◽  
Vol 19 (4) ◽  
pp. 572-579 ◽  
Author(s):  
Gemma Caterina Maria Rossi ◽  
Carmine Tinelli ◽  
Gian Maria Pasinetti ◽  
Giovanni Milano ◽  
Paolo Emilio Bianchi
Keyword(s):  
Quality Of Life ◽  
Dry Eye ◽  
Ocular Surface ◽  
Cross Sectional Study ◽  
Dry Eye Syndrome ◽  
Control Group ◽  
Ocular Surface Disease Index ◽  
Symptom Scale ◽  
Cross Sectional

Purpose To verify the presence of dry eye syndrome (DES) in treated patients with glaucoma and to analyze DES's impact on the patients' quality of life (QOL) versus the control group. Methods In this observational cross-sectional study, 61 patients were enrolled at a clinical practice. Patients were divided into three groups by number of glaucoma drops instilled per day (G1=1 drop/day, G2=2 drops/day, G3=3 drops/day). A control group of 20 subjects was also selected (G0). All subjects were submitted to a complete ocular examination (including tear function and ocular surface status) and completed the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ), Glaucoma Symptom Scale (GSS) questionnaire, and Ocular Surface Disease Index (OSDI). DES was defined as presence of punctate keratitis and decreased break-up time. Statistical analysis was performed applying the Kruskal-Wallis analysis of variance and Mann-Whitney U tests (to compare median values between groups) as well as the χ2 and Fisher test (to verify significant differences). Results A total of 40% of G3 and 39% of G2 patients presented DES versus 11% of G1 and 5% of G0 (p=0.01). QOL was significantly influenced and altered (NEI-VFQ 25 total mean and GSS total mean and symptoms average: p=0.0085, p=0.006, and p=0.03, respectively). OSDI pointed out differences by group: 26% of G2 and 15% of G3 presented moderate OSDI and 15% of G3 and 8.7% of G2 severe OSDI (p>0.05). Conclusions Patients with topically treated glaucoma present DES more often than a similar control group (p=0.01). The presence of DES negatively influences the patient's QOL. The patients with glaucoma's ocular surface status should be evaluated regularly to ensure the timely detection and treatment of pathologic signs on the ocular surface.

scholarly journals Optimization of training of graduates of medical universities for primary accreditation with participation of the student-tutor

2020 ◽  
Vol 23 (4) ◽  
pp. 49-54
Author(s):  
Olga Yu. Kuznetsova ◽  
Anna V. Turusheva ◽  
Zakhar V. Lopatin ◽  
Maria O. Bogdanova ◽  
Olga I. Frolova ◽  
...  
Keyword(s):  
Medical Care ◽  
Main Group ◽  
Educational Process ◽  
Control Group ◽  
Teaching Staff ◽  
Practical Skills ◽  
Training Scheme ◽  
Level Of Knowledge ◽  
Student Mentor

The article is devoted to the study of the effectiveness of training graduates of medical universities when a trained student is included in the educational process, able to fulfill the role of a mentor. All over the world, the number of students is increasing in medical universities every year, but there is no equivalent increase in the teaching staff. One of the potential methods of overcoming the above problems is the use of trained mentors from among peer students. This method was used when students practiced practical skills in a simulation center in anticipation of primary accreditation. The purpose of the study is to optimize the preparation of students for a practical exam in a simulation environment with the help of a student mentor. Of the 468 students of the medical faculty of the North-Western State Medical University named after I.I. Mechnikov, studying in the VI year, was chosen by their colleague, who was trained at the center of simulation technology. A sample of 100 graduates was randomly generated, which were randomized into two groups of 50 people each (the main group in which the training was conducted with the participation of a mentor student and a control group trained under the guidance of teachers from one of the university departments). The most difficult for students was the station simulating the provision of emergency medical care (EMF). The evaluation checklist for checking the quality of the tasks at this station includes 233 points that must be implemented when providing EMF in 13 different situations requiring this type of medical care. To improve the quality of mastering practical skills, a training scheme was developed that allows you to learn the algorithm of actions when providing EMF. A basic assessment of students knowledge and skills revealed a low level of knowledge of diagnostic techniques and emergency assistance. Using the developed training scheme with the help of a student mentor has significantly increased the level of knowledge and practical skills in the provision of EMF. The quality of training in the main group did not significantly differ in most of the assessed parameters from the control group in which classes were held with the teacher. Statistical analysis of the data was performed using the SPSS 20.0 program (SPSS Inc., Chicago, IL, USA).

scholarly journals Usage of 0.4% sodium hyaluronate in complex treatment of pediatric patients with dry eye syndrome against the background of allergic diseases of the organ of vision

2021 ◽  
Vol 9 (2) ◽  
pp. 21-24
Author(s):  
L.S. Vasilyeva ◽  
O.V. Nesterenko ◽  
K.A. Rylkova
Keyword(s):  
Anterior Chamber ◽  
Dry Eye ◽  
Pediatric Patients ◽  
Sodium Hyaluronate ◽  
Allergic Diseases ◽  
Dry Eye Syndrome ◽  
Control Group ◽  
Film Rupture ◽  
Topical Glucocorticoids

Background. In recent years, the prevalence of allergic diseases of the anterior chamber of the eye has increased. They are often accompanied by the development of dry eye syndrome, which can complicate their course. Therefore, it is important to take a comprehensive approach to their diagnosis and treatment. The purpose was to study the effectiveness of 0.4% sodium hyaluronate (Gilays) in children with dry eye syndrome on the background of allergic diseases of the conjunctiva. Materials and methods. The study involved 42 patients (84 eyes) aged 3 to 18 years, who were examined and treated on the basis of Regional Eye Clinic. Patients were treated with local H-1 histamine blockers twice a day for 14 days, f necessary — with topical glucocorticoids by the scheme for 12 days. In the first group (21 patients, 42 eyes), the main treatment was added with the drugs containing 0.2% sodium hyaluronate, used topically 4 times a day for 14 days. In the second group (21 patients/42 eyes), 0.4% sodium hyaluronate (Gilays) was added to the treatment regimen. H-1 histamine blockers were not used systemically. Before starting therapy and 2 weeks later, the following values were evaluated: the changes in the anterior chamber of the eye using biomicroscopy, determination of lacrimal film rupture time, Schirmer 1 test, questionnaire. Conclusions. The use of sodium hyaluronate in the complex therapy of dry eye syndrome in allergic eye diseases is quite effective. The use of 0.4% sodium hyaluronate was more effective compared to the control group. It is advisable to use a questionnaire to communicate with the child, but it is necessary to refine the form of questions to eliminate as much as possible the subjectivity of the data.

scholarly journals Blood antioxidant capacity change in patients with the «dry» form of age-related macular degeneration treated with polarized polychromatic non-coherent light and dynamic electromyostimulation

2012 ◽  
Vol 93 (6) ◽  
pp. 994-996
Author(s):  
F R Saifullina ◽  
R Z Sharafieva ◽  
V I Pogorel’tsev ◽  
F M Fayzrahmanova ◽  
E A Abdulaeva
Keyword(s):  
Visual Acuity ◽  
Antioxidant Capacity ◽  
Macular Degeneration ◽  
Combined Treatment ◽  
Mean Value ◽  
Main Group ◽  
Age Related Macular Degeneration ◽  
Control Group ◽  
Coherent Light ◽  
Age Related

Aim. To assess the antioxidant capacity in patients with the «dry» form of age-related macular degeneration before and after combined treatment with polarized polychromatic non-coherent light and dynamic electromyostimulation. Methods. Two groups of patients with the «dry» form of age-related macular degeneration were examined. 40 patients (80 eyes) from the main group were treated using combined treatment and 39 patients (78 eyes) in the group of control who were treated conventionally. The integral blood antioxidant capacity was measured by galvanometry. Results. Blood antioxidant capacity in healthy subjects is 26.0 kC/l. In patients of the main group blood antioxidant capacity before the treatment was equal to 22.81±0.27 kC/l, compared to 22.17±0.20 kC/l in control group (total mean value 22.49±0.27 kC/l). There was a relevant elevation of the blood antioxidant capacity at the late stages after the treatment - up to 12 months, compared to only 2 months in the control group. Visual acuity in patients of the main group before the treatment was 0.87±0.02, after the treatment was finished - 0.96±0,01 (p 0.001), 2 months after the treatment - 0.95±0.01 (p 0.001), 6 months after the treatment - 0.96±0.01 (p 0.001), 12 months after the treatment - 0.95±0.01 (p 0.001). Visual acuity in patients of the control group before the treatment was 0.91±0.02, after the treatment was finished - 0.95±0.02 (p 0.05), 2 months after the treatment - 0.94±0.02 (p 0.05), 6 months after the treatment - 0.92±0.02 (p 0.05). 12 months after the treatment the visual acuity deteriorated compared to the treatment start and was measured as 0.89±0.02. Conclusion. There is a decrease of blood antioxidant capacity (22.49±0.27 kC/l) in patients with the «dry» form of age-related macular degeneration; a relevant increase of blood antioxidant capacity and visual acuity can be observed up to 12 months after the treatment with polarized polychromatic non-coherent light and dynamic electromyostimulation.

scholarly journals Combined treatment of oligoasthenospermia by postoperative Speroton therapy in patients with varicocele

2020 ◽  
Vol 21 (2) ◽  
pp. 64-69
Author(s):  
E. A. Povelitsa ◽  
V. E. Leanovich ◽  
N. I. Dosta ◽  
O. V. Parhomenko ◽  
A. M. Shesternya
Keyword(s):  
Spermatic Cord ◽  
Varicose Veins ◽  
Combined Therapy ◽  
Combined Treatment ◽  
Sperm Concentration ◽  
Study Groups ◽  
Reproductive Age ◽  
Control Group ◽  
Study Objective ◽  
Before And After

The study objective is to evaluate the effectiveness of the Speroton complex therapy in combined treatment of oligoasthenospermia in patients with varicocele after microsurgical phlebectomy of varicose veins of the spermatic cord.Materials and methods. Microsurgical phlebectomy of the spermatic cord was performed in 40 men (mean age 33.0 ± 2.3 years) with oligoasthenospermia and varicocele. The patients were divided into 2 groups: the main group included 20 men who were treated with the Speroton complex for 3 months in the postoperative period, and the control group included 20 men who did not take Speroton. The spermogram parameters were evaluated before and after the operation.Results. Three months after the start of treatment, a statistically significant improvement in spermogram indicators was noted in all study groups. It was determined that combined therapy that included the Speroton complex administration for 3 months, statistically significantly led to the more considerable increase in sperm parameters than in control group: the sperm concentration increased to 38.6 and 28.9 mln/ml, respectively, the percentage of progressive motile sperm – to 49.2 and 39.4 %, the percentage of motile forms – to 72.2 and 43.8 %, viable forms – to 67.8 and 58.1 %, and the percentage of sperm with DNA fragmentation decreased to 12.1 and 17.2 %, respectively, in the main and control groups.Conclusion. Combined treatment with postoperative Speroton therapy for men of reproductive age with infertility and varicocele determines the more significant improvement in the parameters of sperm than performing only surgical correction of varicocele.

scholarly journals Using bioresonance therapy in treatment of patients with hypothyroidism

2016 ◽  
Vol 97 (4) ◽  
pp. 545-550
Author(s):  
V V Kiryanova ◽  
N V Vorokhobina ◽  
Z H Makhramov
Keyword(s):  
Placebo Group ◽  
Targeted Therapy ◽  
Hormone Replacement ◽  
Combined Treatment ◽  
Thyroid Stimulating Hormone ◽  
Main Group ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Bioresonance Therapy ◽  
Basic Treatment

Aim. To evaluate the effectiveness of using bioresonance therapy in the treatment of patients with hypothyroidism.Methods. Three matched groups of patients with acquired hypothyroidism consisting of 50 people aged 20 to 60 years (mean age 45.6 years) were included in a study. All patients were treated by the same conventional scheme of treatment of hypothyroidism: thyroid hormone replacement drugs. The main group, in addition to replacement therapy received bioresonance therapy. The second group (control) received only pharmacotherapy, the third group (placebo) received pharmacotherapy and simulation of bioresonance therapy procedures. Patients of the main group received 12 daily bioresonance therapy procedures using «Det Professional» device, consisting of two stages: the basic treatment stage and targeted therapy stage. 5 procedures of basic treatment and 7 procedures of targeted therapy were performed.Results. After bioresonance therapy, free thyroxine fraction value in the main group significantly increased in comparison with the control group and the placebo group. Values of thyroid-stimulating hormone after the conducted therapy in the main group significantly decreased compared with the control group and the placebo group. The lipidogram results indicate that the content of high-density lipoproteins in the study group significantly increased compared with the control group and the placebo group. The concentrations of low-density lipoproteins, cholesterol and triglycerides in the main group became significantly lower than in the control group and the placebo group.Conclusion. The obtained results give the evidence of the effectiveness of using bioresonance therapy in combined treatment of patients with hypothyroidism and in achieving stable remission of hypothyroidism.

scholarly journals Non-Conservative Therapy in the Prevention of Subepithelial Fibroplasia after LASEK Hypermetropia Correction

2018 ◽  
Vol 15 (2) ◽  
pp. 200-206
Author(s):  
S. A. Korotkikh ◽  
A. E. Bogachev ◽  
A. S. Shamkin
Keyword(s):  
Dry Eye ◽  
Postoperative Period ◽  
Sodium Hyaluronate ◽  
Early Postoperative Period ◽  
Diagnostic Methods ◽  
Dry Eye Syndrome ◽  
Control Group ◽  
Study Group ◽  
Postoperative Therapy ◽  
Significant Difference

The results of observation of patients who underwent vision eximerlaser correction by the LASEK method regarding medium degree of hyperopia were analyzed.Purpose:to investigate the severity of the «dry eye» syndrome and corneal subepithelial fibroplasia in patients after laser correction of  hyperopia by the LASEK method, and their prevention by reducing  the preservative action on the eye surface.Patients and methods.The study included 40 patients (76 eyes), aged 21–46 years (32.98 ± 1.79) who underwent LASEK surgery for  moderate hyperopia (4.03 ± 0.38 D). Patients were divided into two  groups: 1) control group (20 patients, 37 eyes) — postoperative  therapy included the corneoprotector “Stilavit®” and the preparation  of hyaluronic acid “Oksial®”, containing preservatives;  2) the study group (20 patients, 39 eyes) — postoperative therapy  included the corneoprotector “Hilozar-comod®” and the artificial tear  preparation “Hilo-comod®”, which did not contain reservatives. Ophthalmic examination included, in addition to standard diagnostic  methods, the Norn test, the Schirmer test, the staining of the eye  surface with lissamine green. In addition, a questionnaire was  conducted on a modified OSDI questionnaire; there a section  characterizing the quality of vision (section B) was removed.Results.The analysis of the obtained data showed that in the study group there was less pronounced “dry eye” syndrome at 3,6,12  months after the operation. The maximum difference in the  indicators of the “dry eye” syndrome between the groups was at 3  and 6 months of the postoperative period. When evaluating corneal  subepithelial fibroplasia, maximum attention was paid to the  frequency and the intensity index. It was shown a significant  difference in the intensity of the haze between the study group and the control group by 26.1 % at 3 months, by 62.2 % at 6  months and by 65.3 % 12 months after the operation. Conclusion.Nonconservative therapy with sodium hyaluronate and  dexapanthenol in the early postoperative period and only sodium  hydrolurate allows to reduce the severity of the dry eye syndrome  after laser correction of hypermetropia and, as a result, to reduce  the intensity of haze development by 65.3 %, and its frequency on 11,5 %.

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