scholarly journals Hubungan tingkat pengetahuan dengan perilaku pencegahan kekambuhan luka diabetik

2018 ◽  
Vol 5 (3) ◽  
pp. 233-240
Author(s):  
Agus Priyanto
Keyword(s):  
Rank Test ◽  
Diabetic Patients ◽  
Diabetic Wound ◽  
Spearman Rank ◽  
Wound Recurrence ◽  
Coefficient Corrélation ◽  
Prevention Behavior ◽  
Level Of Knowledge ◽  
Behavioral Prevention ◽  
Diabetic Wounds

ABSTRACTLuka pada pasien diabetes mellitus yang sudah membusuk dan bisa melebar, ditandai dengan jaringan yang mati berwarna kehitaman dan berbau busuk, dan bila tidak tertangani dapat menyebabkan kematian jaringan dan bisa mengakibatkan kematian.Dalam keadan lanjut, amputasi menjadi terapi akhir untuk mencegah pelebaran luka. Penanganan luka pasca operasi dan pengetahuan tentang pencegahan terjadinya luka menjadi hal penting untuk mencegah kekambuhan ulang. Tanpa pengetahuan yang baik tentang perawatan , luka diabetik akan muncul berulang dan mengakibatkan hilangnya bagian tubuh karena kematian jaringan. Tujuan penelitian ini adalah menganalisis hubungan tingkat pengetahuan dengan perilaku pencegahan kekambuhan luka diabetik di Di Ruang Penyakit Dalam RSUD Gambiran Kediri.Desain yang digunakan dalam penelitian ini adalah korelasional. Populasinya pasien Diabed di ruang penyakit Dalam RSUD Gambiran . Sampel diambil dengan teknik consecutive samping sejumlah 29 responden.Variabel independennya adalah tingkat pengetahuan pasien tentang pencegahan luka diabetik dan variable dependennya adalah perilaku pencegahan kekambuhan luka diabetik. Data diambil dengan questioner dan dianalisis dengan Uji Spearman Rank.Hasil penelitian menunjukkan bahwa pengetahuan pasien tentang pencegahan luka diabetik adalah baik sebanyak 24 responden (82,75 %). Perilaku pencegahan luka diabetik sebagian besar adalah cukup 15 orng (51,726 %). Uji Spearman Rank menunjukkan Ada hubungan tingkat pengetahuan dengan perilaku pencegahan luka diabetik di Di Ruang RSUD Gambiran Kota Kediri (spearman rank dengan p = 0,003 < 0,05, artinya H0 ditolak dan H1diterima). Coefficient correlation = 0,404, menunjukkan adanya hubungan ke arah positif artinya semakin baik tingkat pengetahuan maka perilaku pencegahan luka diabetik juga semakin baik. Sebagai tindak lanjut dalam meningkatkan perilaku pencegahan kekambuhan luka dibetik pada pasien yang pernah menderita luka diabetik maupun yang belum pernah, perlu upaya untuk meningkatkan pengetahuan pasien dan kelarga tentang cara perawatan pasien Diabet terutama dalam menjaga kestabilan gula darah dalam batas normal,melalui pola diet dan cara pemeliharaan integritas kulit agar tidak terjadi luka dibetik. Kata Kunci : Pengetahuan, Perilaku, luka Diabetik, kekambuhanABSTRACTWound on diabetic patient signed by blacknumb tissue and badsmell, ifits not hand ledthet issue will numband tousebedie. In advanced circumstances, amputation becomes a final therapy to prevent widening of the wound.Treatment postoperative wounds and knowledge of prevention of injury are important to prevent recurrence. Without good knowledge about treatment, diabetic wounds will recur and cause loss of body parts due to necrotic tissue . The purpose of this study was to analyze the relationship between the level of knowledge with behavioral prevention of diabetic wound recurrence in the Internist Room, Gambiran Kediri Hospital. The design used in this study is correlational. The population is internist patients of Gambiran Hospital. Samples were taken by consecutive techniques totaling 29 respondents. The independent variable is the level of patient knowledge about the prevention of diabetic wounds and the dependent variable is the behavior of diabetic wound recurrence prevention. The data was taken with a questionnaire and analyzed by the Spearman Rank Test. The results showed that the patient's knowledge of the prevention of diabetic wounds was good as many as 24 respondents (82.75%). Preventive behavior of diabetic wounds is mostly 15 people (51.72%). The Spearman Rank test shows that there is a relationship between the level of knowledge with the behavioral prevention of diabetic wounds in the internist room of Gambiran Hospital (spearman rank with p = 0.003 <0.05, meaning that H0 is rejected and H1 is accepted). Coefficient correlation = 0.404, indicating a positive relationship means that the better the level of knowledge, the better the prevention behavior of diabetic wounds. As a follow-up in improving the prevention behavior of randomized wound recurrence in patients who have suffered from diabetic wounds or who have never before, it is necessary to increase the knowledge of patients and family members on how to treat diabetic patients, especially in maintaining blood sugar stability within normal limits, through diet and methods. maintenance of the integrity of the skin so that no wounds occur.Keywords: Knowledge, Behavior, Diabetic wounds, recurrence

Updates in Diabetic Wound Healing, Inflammation, and Scarring

2021 ◽  
Author(s):  
Nina Dasari ◽  
Austin Jiang ◽  
Anna Skochdopole ◽  
Jayer Chung ◽  
Edward Reece ◽  
...  
Keyword(s):  
Wound Healing ◽  
Disease Process ◽  
Wound Dehiscence ◽  
Diabetic Patients ◽  
Wound Infections ◽  
Diabetic Wound ◽  
Complex Process ◽  
Diabetic Wound Healing ◽  
Almost All ◽  
Diabetic Wounds

AbstractDiabetic patients can sustain wounds either as a sequelae of their disease process or postoperatively. Wound healing is a complex process that proceeds through phases of inflammation, proliferation, and remodeling. Diabetes results in several pathological changes that impair almost all of these healing processes. Diabetic wounds are often characterized by excessive inflammation and reduced angiogenesis. Due to these changes, diabetic patients are at a higher risk for postoperative wound healing complications. There is significant evidence in the literature that diabetic patients are at a higher risk for increased wound infections, wound dehiscence, and pathological scarring. Factors such as nutritional status and glycemic control also significantly influence diabetic wound outcomes. There are a variety of treatments available for addressing diabetic wounds.

A dual functional collagen scaffold coordinates angiogenesis and inflammation for diabetic wound healing

2020 ◽  
Vol 8 (22) ◽  
pp. 6337-6349
Author(s):  
Ge Long ◽  
Dingyang Liu ◽  
Xi He ◽  
Yeyu Shen ◽  
Yannan Zhao ◽  
...  
Keyword(s):  
Wound Healing ◽  
Collagen Scaffold ◽  
Diabetic Patients ◽  
Diabetic Wound ◽  
Dual Functional ◽  
Persistent Inflammation ◽  
Diabetic Wound Healing ◽  
Diabetic Wounds ◽  
Impaired Angiogenesis

Chronic diabetic wounds, which are associated with persistent inflammation and impaired angiogenesis, occur frequently in diabetic patients.

scholarly journals Mathematical Model Predicts that Acceleration of Diabetic Wound Healing is Dependent on Spatial Distribution of VEGF-A mRNA (AZD8601)

2021 ◽  
Author(s):  
S. Michaela Rikard ◽  
Paul J. Myers ◽  
Joachim Almquist ◽  
Peter Gennemark ◽  
Anthony C. Bruce ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Wound Healing ◽  
Spatial Distribution ◽  
Surrounding Tissue ◽  
Diabetic Patients ◽  
Model Parameters ◽  
Diabetic Wound ◽  
Diabetic Wound Healing ◽  
Diabetic Wounds ◽  
The Impact

Abstract Introduction Pharmacologic approaches for promoting angiogenesis have been utilized to accelerate healing of chronic wounds in diabetic patients with varying degrees of success. We hypothesize that the distribution of proangiogenic drugs in the wound area critically impacts the rate of closure of diabetic wounds. To evaluate this hypothesis, we developed a mathematical model that predicts how spatial distribution of VEGF-A produced by delivery of a modified mRNA (AZD8601) accelerates diabetic wound healing. Methods We modified a previously published model of cutaneous wound healing based on coupled partial differential equations that describe the density of sprouting capillary tips, chemoattractant concentration, and density of blood vessels in a circular wound. Key model parameters identified by a sensitivity analysis were fit to data obtained from an in vivo wound healing study performed in the dorsum of diabetic mice, and a pharmacokinetic model was used to simulate mRNA and VEGF-A distribution following injections with AZD8601. Due to the limited availability of data regarding the spatial distribution of AZD8601 in the wound bed, we performed simulations with perturbations to the location of injections and diffusion coefficient of mRNA to understand the impact of these spatial parameters on wound healing. Results When simulating injections delivered at the wound border, the model predicted that injections delivered on day 0 were more effective in accelerating wound healing than injections delivered at later time points. When the location of the injection was varied throughout the wound space, the model predicted that healing could be accelerated by delivering injections a distance of 1–2 mm inside the wound bed when compared to injections delivered on the same day at the wound border. Perturbations to the diffusivity of mRNA predicted that restricting diffusion of mRNA delayed wound healing by creating an accumulation of VEGF-A at the wound border. Alternatively, a high mRNA diffusivity had no effect on wound healing compared to a simulation with vehicle injection due to the rapid loss of mRNA at the wound border to surrounding tissue. Conclusions These findings highlight the critical need to consider the location of drug delivery and diffusivity of the drug, parameters not typically explored in pre-clinical experiments, when designing and testing drugs for treating diabetic wounds.

scholarly journals Diabetic wound infection: A review on microbial population and infection control

2020 ◽  
pp. 36-43
Author(s):  
Nur Amiera Syuhada Rozman ◽  
Woei Yenn Tong ◽  
Chean Ring Leong ◽  
Wen-Nee Tan ◽  
Syarifah Ab Rashid
Keyword(s):  
Wound Infection ◽  
Wound Dressing ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Single Species ◽  
Bacterial Biofilm ◽  
Diabetic Patients ◽  
Diabetic Wound ◽  
Quality Life ◽  
Diabetic Wounds

A diabetic foot ulcer is one of the major complications of diabetes and it leads to lower extremity amputation in patients. This review explores the current research on microbial populations on diabetic wounds, and also treatment alternatives to combat the infection on chronic diabetic wounds. The microbial communities exist in diabetic wound infection are diverse. Microbes rarely survived in single species of planktonic cells. They usually exist in a complex polymicrobial biofilm population which consists of different types of microorganisms. Furthermore, the development of bacterial biofilm on the wound that usually consists of multidrug-resistant pathogens also delayed the wound healing. To overcome this problem, many types of modern wound dressing were developed including hydrocolloid, hydrogel, alginate and collagen wound dressing. Besides, modern biotechnological advancements such as cell therapy, bioengineered skin, dermal scaffolds, tissue-engineered artificial skin and growth factors were also employed to promote the recovery of the wound. In conclusion, diabetes mellitus is a major health care challenge worldwide. Diabetic patients are at risk for developing foot ulcer which ultimately leads to amputation; hence a safe and effective alternative treatment is required to improve diabetic patients’ quality life.

scholarly journals Healing Effects of Photobiomodulation on Diabetic Wounds

2019 ◽  
Vol 9 (23) ◽  
pp. 5114
Author(s):  
Nicolette Houreld
Keyword(s):  
Wound Healing ◽  
Wound Repair ◽  
Chronic Wounds ◽  
Diabetic Patients ◽  
Diabetic Wound ◽  
Recurrence Rates ◽  
Speed Up ◽  
Diabetic Wound Healing ◽  
Underlying Mechanisms ◽  
Diabetic Wounds

Diabetic patients frequently develop chronic ulcers of the lower extremities, which are a frequent cause for hospitalization and amputation, placing strain on patients, their families, and healthcare systems. Present therapies remain a challenge, with high recurrence rates. Photobiomodulation (PBM), which is the non-invasive application of light at specific wavelengths, has been shown to speed up healing of chronic wounds, including diabetic foot ulcers (DFUs). PBM produces photophysical and photochemical changes within cells without eliciting thermal damage. It has been shown to promote tissue regeneration and speed up wound repair by reducing inflammation and oxidative stress, accelerating cell migration and proliferation, and promoting extracellular matrix production and release of essential growth factors. The shortage of rigorous, well-designed clinical trials makes it challenging to assess the scientific impact of PBM on DFUs, and lack of understanding of the underlying mechanisms also hinders the conventional use of this therapy. This review gives a glimpse into diabetic wound healing and PBM, and the effects of PBM on diabetic wound healing.

scholarly journals The Degree of Diabetic Wounds Affects Kidney Function Damage

2019 ◽  
Vol 9 (2) ◽  
pp. 159-166
Author(s):  
Emyk Windartik ◽  
Ima Rahmawati ◽  
Ita Ainun Jariyah ◽  
Raras Merbawani ◽  
Indah Lestari ◽  
...  
Keyword(s):  
Kidney Function ◽  
Circulatory System ◽  
Sampling Technique ◽  
Diabetic Patients ◽  
Diabetic Wound ◽  
Cross Sectional ◽  
High Sugar ◽  
Sugar Levels ◽  
Diabetic Wounds ◽  
The Relationship

Background: The peripheral neuropathy is the cause of hospitalization for patients with diabetes mellitus (DM) and damages kidney function due to the circulatory system with high sugar levels. High sugar levels in DM patients with diabetic wounds can trigger glomerular damage resulting in the decrease of kidney function.Purpose: This study aims to analyze the relationship between the degree of diabetic wounds and kidney functions in patients with DM.Methods: A cross-sectional study was conducted on 723 DM patients who experienced diabetic wounds in a hospital in Mojokerto, East Java, Indonesia. A purposive sampling technique was used to recruit the samples. The data of this study were medical records of diabetic patients. A simple linear regression test was employed to analyze the data.Results: The result showed that the degree of diabetic wound was significantly related to kidney function damage (p=0.000). The relationship between the degree of diabetic wounds and the decline in kidney function was shown by an R-squared value of 0.768, meaning that the degree of diabetic wound affected the decline of kidney function by 76.8%, while the 23.2% was affected by other factors.Conclusion:The degree of diabetic injury affects the decline of kidney function in DM patients by 76.8%. Nurses should do health promotion about controlling blood sugar levels in DM patients with the prevention of four pillars of diabetes, including education, nutrition, physical activity, and stress. 

scholarly journals Sustained Oxygenation Accelerates Diabetic Wound Healing by Simultaneously Promoting Epithelialization and Angiogenesis, and Decreasing Tissue Inflammation

2021 ◽  
Author(s):  
Ya Guan ◽  
Hong Niu ◽  
Zhongting Liu ◽  
Yu Dang ◽  
Jie Shen ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
Dermal Fibroblasts ◽  
Diabetic Patients ◽  
Diabetic Wound ◽  
Oxygen Release ◽  
Ros Scavenging ◽  
M1 Macrophage ◽  
Diabetic Wound Healing ◽  
Diabetic Wounds

Non-healing diabetic wound is one of the most common complications for diabetic patients. Chronic hypoxia is among the prominent factors that delay the wound healing process. Therefore, sustained oxygenation to alleviate hypoxia is hypothesized to promote diabetic wound healing. Yet it cannot be achieved by current clinical approaches including hyperbaric oxygen therapy. Herein, we developed a sustained oxygenation system consisting of oxygen-release microspheres and a reactive oxygen species (ROS)-scavenging hydrogel. The hydrogel was used to capture the ROS that is elevated in the diabetic wounds, and that may be generated due to oxygen release. The sustainedly released oxygen augmented survival and migration of keratinocytes and dermal fibroblasts; promoted angiogenic growth factor expression, and angiogenesis in the diabetic wounds; and decreased M1 macrophage density. These effects led to a significant increase of wound closure rate. These findings reveal that sustained oxygenation alone without using drugs is capable of healing diabetic wounds.

scholarly journals COMMITMENT MOTHER AND BEHAVIORAL PREVENTION OF PICKY EATING ON TODDLER

2020 ◽  
Vol 9 (2) ◽  
pp. 80-86
Author(s):  
Dona Muji Fitriana ◽  
Yuni Sufyanti Arief ◽  
Ilya Krisnana
Keyword(s):  
Child Growth ◽  
Validity And Reliability ◽  
Cross Sectional ◽  
Picky Eating ◽  
The Public ◽  
Central Java ◽  
Coefficient Corrélation ◽  
Prevention Behavior ◽  
Cross Sectional Design ◽  
Behavioral Prevention

Background: Picky eating is a picky behavior that can be interpreted as a rejection of certain types of food or fear of trying new foods. Picky eating can make some problems inadequacy of nutrition and impact on child growth if it's not properly handled and left prolongObjectives: The purpose of this study was determined to describe the relationship between commitment mothers and behavioral prevention of picky eating on toddler.Methods: The research used correlational analytic study with cross-sectional design. The Independent variable in this study is mother’s commitment and the dependent variable is behavioral prevention of picky eating. The population was mothers with toddler age children in the working area at the Public Health Center of Kedawung 1, Sragen, Central Java. A sample of 120 mothers were selected by purposive sampling. Data were collected using questionnaires demographic of the respondent, mother’s commitment, and behavioral prevention of picky eating that compiled by the researcher. This questionnaire has been tested for validity and reliability, and then analyzed used Spearman-rank test.Results: The results of this study showed that the mother's commitment to picky eating prevention behavior had a significant relationship (p <0.05) and have a coefficient correlation with positive value (r=0.535).Conclusion: The good mother’s commitment can make a good behavioral prevention of picky eating in toddlers. There needs to be more research on the factors that influence the behavioral prevention of picky eating. Keywords: Commitment, Mother, Picky Eating

scholarly journals PENGETAHUAN DAN KEPATUHAN PENDERITA DIABETES MELLITUS DALAM MELAKUKAN LATIHAN FISIK

2015 ◽  
Vol 1 (1) ◽  
pp. 33
Author(s):  
Susanti Susanti
Keyword(s):  
Diabetes Mellitus ◽  
Physical Exercise ◽  
Rank Correlation ◽  
Sampling Technique ◽  
Rank Test ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Spearman Rank ◽  
Purposive Sampling ◽  
Patients With Diabetes

Patients with Diabetes Mellitus is necessary therapeutic regimen for prevention or treatment, care to help patients to prevent complications. One is by providing information to physical activity to increase knowledge about the effects of Diabetes Mellitus patients and physical exercise. The purpose of this study was to determine the relationship of knowledge with diabetic patient compliance in physical exercise. The research method is a correlation with cross sectional approach, the research sample are 39 people with purposive sampling technique. The tools used assess knowledge and compliance of respondents using a questionnaire. Data collection is done coding, scoring, and tabulation and correlation test by Spearman Rank Test. The results showed that the results of the statistical test of Spearman rank correlation significance value (<0.05), it shows there is a relationship then H1 accepted which means that there is a relationship between knowledge and compliance of patients with Diabetes Mellitus in physical exercise. Results of this study can assist clients in improving the quality of life program Diabetes Mellitus patients through regular physical exercise. Suggested to the nurse to use the results of this study as a reference for improving services in diabetic patients leading to the needs of the patient in physical exercise. Penderita Diabetes Mellitus membutuhkan tindakan terapeutik untuk pencegahan atau penatalaksanaan, dan tindakan lain untuk mencegah komplikasi. Hal tersebut dapat dilakukan denga menambah informasi tentang aktifitas fisik untuk meningkatkan pengetahuan pasien Diabetes Mellitus. Tujuan penelitian ini untuk mengidentifikasi hubungan antara pengetahuan dengan kepatuhan penderita Diabetes Mellitus dalam melakukan latihan fisik. Metode penelitian menggunakan korelasi dengan pendekatan potong lintang. Sampel terdiri dari 39 responden dan menggunakan teknik purposive sampling. Pengukuran pengetahuan dan kepatuhan penderita Diabetes mellitus dalam melakukan latihan fisik menggunakan kuesioner. Data diolah menggunakan Spearman rank test. Hasil menunjukkan signifikan (<0,05). Hal ini menunjukkan terdapat hubungan antara pengetahuan dan kepatuhan penderita Diabetes Mellitus dalam melakukan latihan fisik. Hasil ini dapat menunjang penderita Diabetes Mellitus untuk meningkatkan kualitas hidup dan dapat digunakan sebagai sumber pustaka bagi perawat dalam meningkatkan pelayanan bagi penderita Diabetes Mellitus dalam melakukan latihan fisik. DOWNLOAD FULL TEXT PDF >>

HUBUNGAN TINGKAT PENGETAHUAN BIDAN TENTANG INISIASI MENYUSU DINI DENGAN PENATALAKSANAAN INISIASI MENYUSU DINI DI RUMAH SAKIT BHAYANGKARA PALEMBANG TAHUN 2017

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Juliana Widyastuti Wahyuningsih Juliana Widyastuti Wahyuningsih
Keyword(s):  
Data Analysis ◽  
Correlation Study ◽  
Early Initiation ◽  
Rank Test ◽  
P Value ◽  
Breastfeeding Initiation ◽  
Knowledge Level ◽  
Spearman Rank ◽  
Correlational Design ◽  
Level Of Knowledge

ABSTRAK   Inisiasi Menyusu Dini (early initiation) atau permulaan menyusu dini adalah membiarkan bayi baru lahir untuk merangkak ke arah payudara ibunya, menemukan puting susu, kemudian menyusu sendiri setidaknya selama satu jam.Tujuan penelitian ini untuk mengetahui hubungan tingkat pengetahuan bidan tentang inisiasi menyusu dini dengan pelaksanaan Inisiasi Menyusu Dini di Rumah Sakit Bhayangkara Palembang Tahun 2017. Desain penelitian bersifat Correlation Study. Penelitian dilakukan di Rumah Sakit Bhayangkara Palembang bulan Februari 2017 sampai dengan Mei 2017. Jumlah sampel yang digunakan sebanyak 11 orang. Subjek penelitian adalah bidan di Rumah Sakit Bhayangkara Palembang. Analisis penelitian dengan menggunakan Spearman Rank. Hasil penelitian menunjukkan pengetahuan bidan tentang inisiasi menyusu dini dalam kategori baik sebanyak 7 orang (63,3%), cukup 3 orang (27,3%), dan kurang sebanyak 1 orang (9,1%). Sedangkan untuk pelaksanaan inisiasi menyusu dini dalam kategori baik sebanyak 4 orang (36,4%), cukup sebanyak 5 orang (45,4%), dan kurang sebanyak 2 orang (18,2%). Analisis dihasilkan nilai p-value 0,010. Nilai rhoxy sebesar 0,736. Kesimpulannya ada hubungan antara tingkat pengetahuan bidan tentang inisiasi menyusu dini dengan pelaksanaan inisiasi menyusu dini di Rumah Sakit Bhayangkara Palembang Tahun 2017.   ABSTRACT Early initiation or early breastfeeding is to allow newborns to crawl toward their mother's breasts, find their nipples, and then nursed themselves for at least one hour. The purpose of this study is to know the correlation between midwife knowledge level of early breastfeeding initiation and implementation Early Breastfeeding Initiation at Bhayangkara Palembang Hospital 2017. This study used correlational design. This study was conducted at Bhayangkara Palembang Hospital in February 2017 sampai dengan May 2017. The samples were 11 people. The study subjects were the midwives at Bhayangkara Palembang Hospital. The data analysis used Spearman Rank test. The results of study indicated that the midwives with good level of knowledge about early breastfeeding initiation were seven people (63.3%), with sufficient level of knowledge were three people (27.3%), and with poor level of knowledge was 1 person (9.1%). The midwives with the implementation of early breastfeeding initiation in good category were 4 people (36.4%), in sufficient category were 5 people (45.4%), and in poor category were 2 people (18.2%). The results of analysis obtained the p-value 0.010. The results of analysis obtained the p-value 0.010. The rhoxy value of 0.736. The conclusion was that there was a correlation between the midwives’ levels of knowledge about early breastfeeding initiation to its implementation at Bhayangkara Palembang Hospital.  

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