scholarly journals PENGARUH PEMBERIAN EKSTRAK RUMPUT LAUT COKELAT (Sargassum duplicatum) TERHADAP PENINGKATAN KADAR HEMOGLOBIN PADA DARAH TIKUS JANTAN (Rattus norvegicus) GALUR WISTAR ANEMIA YANG DI INDUKSI NaNO2

2021 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Emy Noviana Sandy ◽  
Liliawanti Liliawanti ◽  
Wachjudi Kurnia
Keyword(s):  
Medical Condition ◽  
Brown Seaweed ◽  
Hemoglobin Level ◽  
Male Rats ◽  
Deficiency Anemia ◽  
Control Group ◽  
Control Group Design ◽  
White Rats ◽  
Blood Hemoglobin ◽  
Average Hemoglobin

<p><strong>ABSTRACT</strong></p><p><strong>Background: </strong>In Indonesia, the prevalence of iron deficiency anemia reaches 25,2 percent, it indicates that anemia is a medical condition in society that needs attention. Brown seaweed (<em>Sargassum duplicatum</em>) is a  group of algae that contains minerals such as iron and vitamin B12. So that the content in <em>Sargassum duplicatum </em>can be used for anemia therapy that serves as the main forming hemoglobin.</p><p><strong>Objective: </strong>The purpose of this experimental research was to determine the administration of <em>Sargassum duplicatum</em> affects the increase in blood haemoglobin levels of rats that are anemia induced NaNO2..</p><p><strong>Methods: </strong>This research used the Post-test only control group design, the samples were 30 male rats divided into 3 treatment groups (K<sub>0</sub>, K<sub>1</sub>, and K<sub>2</sub>). The process of treating anemia in rats using sodium nitrite (NaNO2) at a dose of 125 mg / KgBB. K<sub>0</sub> group is a group that is not treated. K<sub>1</sub> group is a group that was given NaNO2 for 18 days without dieting <em>Sargassum duplicatum</em>. The K<sub>2</sub> group was the group that was given NaNO2 for 18 days and received the <em>Sargassum duplicatum</em> diet at a dose of 2.45 g/kgBB for 14 days.</p><p><strong>Result: </strong>From this research it can be seen that K<sub>0</sub> has an average hemoglobin level of 12,71 g/dL, K<sub>1</sub> has an average hemoglobin level of 11.96 g / dL, and K<sub>2</sub> has an average hemoglobin level of 12,99 g/dL which shows that descriptively there is a difference between groups K<sub>1</sub> and K<sub>2</sub>. Based on the Kruskal-Wallis statistical test, a value of 0,290 was obtained so that p &gt; 0.05 showed that H0 was accepted, which means there was no difference in the administration of <em>Sargassum duplicatum</em> in increasing blood hemoglobin levels in anemic rats.</p><p><strong>Conclusion: </strong>From the results of this research, the conclusion in descriptively there was an increase in the blood hemoglobin level of white rats in the group receiving <em>Sargassum duplicatum</em> extract therapy but it was not statistically significant.</p>Keywords: <em>Sargassum duplicatum, haemoglobin, NaNO<sub>2</sub>, anemia</em>

scholarly journals PENINGKATAN KADAR HEMOGLOBIN (Hb) PADA IBU HAMIL DENGAN ANEMIA DENGAN KONSUMSI JUS JAMBU BIJI (PSIDIUM GUAJAVA. L )

2021 ◽  
Vol 7 (1) ◽  
pp. 109-115
Author(s):  
Neneng Siti Lathifah ◽  
Zarma H ◽  
Nurul Isnaini
Keyword(s):  
Pregnant Women ◽  
Health Center ◽  
Psidium Guajava ◽  
Hemoglobin Level ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Equivalent Control ◽  
Average Hemoglobin

IMPROVEMENT OF HEMOGLOBIN (Hb) LEVELS IN PREGNANT WOMEN WITH ANEMIA WITH THE CONSUMPTION OF JAMBU SEEDS (PSIDIUM GUAJAVA. L) ABSTRACT Background Anemia in pregnancy is a national problem because it reflects the socio-economic condition of the community and its influence is very large on the quality of human resources. The incidence of anemia in pregnant women 2018 in Pesisir Barat Regency is 29.9%. The incidence of anemia in pregnant women at Krui Health Center is 67.5%. The purpose of this study is to know the effect of giving guava juice (Psidium Guajava. L) to the increase of hemoglobin (Hb) levels in pregnant women with anemia in Krui health center in 2019.Methods Quantitative Research Type, the research design is a quasi-experimental method with a Non-equivalent Control Group Design approach. The population in this study were as many as 60 second trimester pregnant women and third trimester who had anemia, a sample of 30 pregnant women. 15 people were given treatment with guava fruit juice and Fe tablets, and 15 people were given treatment with Fe tablets, with inclusion criteria Willing to be respondents, Willing to consume guava juice, Pregnant women with mild and moderate anemia with hemoglobin levels (Hb 7.9 - 10 g / dl). With purposive sampling sampling technique. Analyze data with T-test (univariat and bivariat).The results showed an average hemoglobin level before consumption of guava juice and Fe tablets of 9.72 gr / dl, the average hemoglobin level after consumption of guava juice and Fe tablets was 11.13 gr / dl, the average hemoglobin level before consumption of Fe tablets of 9.80 gr / dl, the average hemoglobin level after consumption of FE tablets was 10.60 gr / dl. Conclusion It was known that there was an effect of giving guava juice (Psidium Guajava. L) to Hb levels in pregnant women with anemia in Krui Public Health Center, West Coast District in 2019. The results of the t test were p value 0,000 <α (0.05).Suggestion  It is recommended for health workers, especially midwives, to encourage pregnant women to consume guava juice as a companion to Fe because it can raise hemoglobin levels in pregnant women. Keywords              : Guava Juice, Tablets Fe, Hemoglobin Level ABSTRAK Latar Belakang Anemia pada kehamilan merupakan masalah nasional karena mencerminkan keadaan sosial ekonomi masyarakat dan pengaruhnya sangat besar terhadap kualitas sumber daya manusia. Angka kejadian anemia pada ibu hamil tahun 2018 di Kabupaten Pesisir Barat adalah sebesar 29,9%. Angka kejadian anemia pada ibu hamil di Puskesmas Krui sebesar 67,5%.Tujuan dari penelitian ini adalah diketahui Pengaruh Pemberian Jus Jambu Biji (Psidium Guajava. L) Terhadap Peningkatan Kadar Hemoglobin (Hb) pada Ibu Hamil dengan Anemia di Puskesmas Krui Tahun 2019.Metode Jenis Penelitian Kuantitatif, rancangan penelitian metode quasi eksperimen dengan pendekatan Non-equivalent Control Group Design. Populasi dalam penelitian ini adalah sebanyak 60 orang ibu hamil trimester II dan trimester III yang mengalami anemia, Sampel sebanyak 30 ibu hamil. 15 orang diberikan perlakuan dengan jus jambu biji dan tablet Fe, dan 15 orang diberikan perlakun dengan tablet Fe, dengan kriteria inklusi Bersedia menjadi responden, Bersedia mengkonsumsi jus jambu biji, Ibu hamil dengan anemia ringan dan sedang dengan kadar hemoglobin (Hb 7,9 – 10 g/dl). Dengan teknik sampling purposive sampling. Analisa data dengan uji T-test (univariat dan bivariat).Hasil penelitian menunjukan rata-rata kadar hemoglobin sebelum konsumsi jus jambu biji dan tablet Fe sebesar 9,72 gr/dl, rata-rata kadar hemoglobin setelah konsumsi jus jambu biji dan tablet Fe sebesar 11,13 gr/dl, rata-rata kadar hemoglobin sebelum konsumsi tablet Fe sebesar 9,80 gr/dl, rata-rata kadar hemoglobin setelah konsumsi tablet Fe sebesar 10,60 gr/dl.Kesimpulan Diketahui Ada Pengaruh Pemberian Jus Jambu Biji (Psidium Guajava. L) Terhadap Kadar Hb pada Ibu Hamil dengan Anemia di Puskesmas Krui Kabupaten Pesisir Barat Tahun 2019. Hasil uji t didapat p value 0,000 < α (0,05).Saran bagi tenaga kesehatan khususnya bidan agar menganjurkan kepada ibu hamil untuk mengkonsumsi jus jambu biji sebagai pendamping Fe karena dapat menaikkan kadar hemoglobin pada ibu hamil. Kata Kunci            : Jus Jambu Biji, Tablet Fe, Kadar hemoglobin

scholarly journals Pengaruh pemberian rumput laut sargassum sp terhadap kadar hemoglobin dan feritin serum

2016 ◽  
Vol 5 (1) ◽  
pp. 7-13
Author(s):  
Anita Yuniarti ◽  
Soeharyo Hadisaputro ◽  
Nyoman Suci W
Keyword(s):  
Serum Ferritin ◽  
Ferritin Level ◽  
Wistar Rat ◽  
Hemoglobin Level ◽  
Male Rats ◽  
Control Group ◽  
Iron Level ◽  
Tropical Country ◽  
Control Group Design ◽  
Marine Plants

Background : Anemia is a global phenomenon involving developing countries. Fifty percent of anemia cases is caused by iron deficiency. Indonesia is a tropical country that is rich in various kinds of marine plants and still not used optimally.Sargassum sp is one of high iron contains seaweed but still less utilized. Objectives: the aim of this study was to analyze the influence of Sargassum sp on hemoglobin and serum ferritin level. Methods : a simple randomized with pre and posttest control group design was used in this study. Sixteen Wistar male rats were divided into 2 groups (1) control (2) treatment and fed with Sargassum sp 0,49 g for 14 days. During the treatment pre and post hemoglobin and serum ferritin was measured. Results : : iron level in Sargassum sp was 122,37mg/g and Pb level was 0,00009%. In the treatment group hemoglobin level was significantly increased 5,24 mg/dl (p<0,05) and serum ferritin was increased 4,20 µg/ml (p>0,05). Conclusion : sargassum sp increased hemoglobin level on anemic wistar rat but not in serum ferritin significantly. 

scholarly journals Effect of Giving Mahkota Dewa Fruits (Phaleria Macrocarpa) Extract to Epithelialization In Incision Wound of White Rats (Rattus Norvegicus)

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Idola Perdana Sulistyoning Suharto
Keyword(s):  
Treatment Group ◽  
Rattus Norvegicus ◽  
Male Rats ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
White Rats ◽  
Significant Difference ◽  
Phaleria Macrocarpa ◽  
Incision Wound

The research purpose was to analysis effect of giving mahkota dewa fruits (Phaleria macrocarpa) extract to epithelialization in incision wound of white rats (Rattus norvegicus). The method was randomized posted-only control group design. There were 30 male rats (Rattus norvegicus) grouped on control and treatment group. Control group divided into three groups (KK1, KK2, KK3) and also treatment group divided into three groups (KP1, KP2, KP3). Control group just given CMC 1% peroral without mahkota dewa fruits extract, the treatment group given mahkota dewa fruits extract 22.5 mg/kg body weight. The data was analyzed by Kruskall Wallis. Based on Kruskall Wallis test, obtained result that there was a significant difference (p<0.05) epithelialization variable with p value p = 0.000 between control and treatment group. And based on One-way Anova test, obtained result that there was a significant difference (p<0.05) with p value p =0.000 between control and treatment group. The conclusion of this research was giving mahkota dewa fruits (Phaleria macrocarpa) extract can increase epithelialization in incision wound of white rats (Rattus norvegicus). Keywords : Mahkota Dewa Fruits (Phaleria Macrocarpa) Extract, Epithelialization, Incision Wound 

scholarly journals Pengaruh suplementasi tablet fe mingguan dan harian terhadap kepatuhan minum tablet Fe dan perubahan kadar hemoglobin pada ibu hamil di Kabupaten Bantul Yogyakarta

2005 ◽  
Vol 2 (2) ◽  
pp. 45
Author(s):  
Dwi Susetyo ◽  
Mohammad Hakimi ◽  
Hamam Hadi
Keyword(s):  
Pregnant Women ◽  
Iron Status ◽  
Multiple Logistic Regression Analysis ◽  
Hemoglobin Level ◽  
Deficiency Anemia ◽  
Control Group ◽  
Folate Supplementation ◽  
Control Group Design ◽  
Significant Difference ◽  
Weekly Group

Background: In Indonesia, in 1995, 50.9% pregnant women suffer from Iron Deficiency Anemia (IDA).Objective: To compare the effect of weekly iron/folate vs standard daily iron/folate supplementation in pregnant women on compliance and hemoglobin level.Methods: The study was a quasi-experimental, non-equivalent control group design. Pregnant women with 20-28 week gestation were enrolled in this study in Bantul District. They were divided into two groups. One group (n=70), in Pajangan and Sewon Sub District, was given 120 mg iron/0,50 mg folate once a week, and the second group (n=65), in Bambang Lipuro and Pundong Sub District, received 60 mg iron/0,25 mg folate per day. Compliance with supplementation was assessed by the women self-reporting, pill count, and stool test. To measure hemoglobin level, the cyanmethemoglobin method was conducted.Results: Compliance was significantly higher in the weekly group (84.69% compared with 71.94%, p=0,004). A multiple logistic regression analysis indicated odds ratio 6.605, it means that in the weekly group compliance was 6,6 times higher than in the daily group. Hemoglobin level increased in both groups. There was no significant difference between groups for changes in hemoglobin. Initial haemoglobin values for the weekly (m=11.61 g/dl) and daily (m=11.27 g/dl) groups as well as final hemoglobin values (11.99 g/dl and 11.83 g/dl, respectively) did not differ significantly between the two groups.Conclusion: Supplementation on a weekly basis is as effective as daily supplementation in improving iron status in pregnant women. In the weekly group, compliance can be ensured.

scholarly journals Pengaruh Pemberian Ekstrak Rumput Laut Cokelat (Sargassum duplicatum) terhadap Peningkatan Kadar Hematokrit pada Darah Tikus Putih Jantan Galur Wistar (Rattus norvegicus) Anemia yang di Induksi NaNO2

2020 ◽  
Vol 3 (2) ◽  
pp. 38
Author(s):  
Ayu Mayang A. P. ◽  
Liliawanti Liliawanti ◽  
Wachjudi Kurnia
Keyword(s):  
Rattus Norvegicus ◽  
White Male ◽  
Brown Seaweed ◽  
Negative Control ◽  
Laboratory Method ◽  
The Body ◽  
Male Rats ◽  
Control Group ◽  
Control Group Design ◽  
Significant Difference

<p>Anemia is still a high prevalence disease in Indonesia, caused by a lack of iron in the body. The components from brown seaweed such as cobalamin (vitamin B12), pyridoxine (vitamin B6), chlorophyll and iron (Fe) can increase red blood cells in the body. The purpose of this research was to determine the effect of brown seaweed (<em>Sargassum duplicatum</em>) which can increase hematocrit levels in the blood of white male wistar strain rat (<em>Rattus norvegicus</em>) suffered from anemia in induction NaNO<sub>2</sub>.</p><p>            This research uses an experimental laboratory method with a post test only control group design. The samples were 30 male rats divided into 3 treatment groups, the negative control group (K<sub>0</sub>) without treatment, the positive control (K<sub>1</sub>) be treated anemia given NaNO<sub>2</sub> for 18 days without <em>Sargassum duplicatum </em>extract and treatment group (K<sub>2</sub>) treated with anemia given NaNO<sub>2</sub> for 18 days without <em>Sargassum duplicatum </em>extract at a dose of 2,45gr / kgBB. On the 40<sup>th</sup> day, a blood sample was taken, then measured the hematocrit level.</p><p>            The results showed that the mean number of blood hematocrit levels in K<sub>2</sub> was higher than K<sub>1</sub>, it showed a significant difference descriptively. Based on the Kruskal-Wallis test, a value of 0.260 was obtained that p &gt; 0,05 showed that there were no statistically significant differences between groups of experimental animals.</p><p>            From the results of this research, the conclusion is the administration of brown seaweed extract (<em>Sargassum duplicatum</em>) descriptively increased, but not statistically significant.</p><p> </p><p><strong>Keywords :</strong> Anemia, hematocrit, <em>Sargassum duplicatum</em>, NaNO<sub>2</sub></p>

scholarly journals THE EFFECTIVENESS OF CORIANDER (Coriandrum sativum L.) EXTRACTS ON REDUCING THE BLOOD SUGAR LEVELS OF ALLOXAN INDUCED WISTAR MALE RATS (Rattus norvegicus L.)

2020 ◽  
Vol 6 (1) ◽  
pp. 36-44
Author(s):  
Kalvin Dersing
Keyword(s):  
Blood Sugar ◽  
Rattus Norvegicus ◽  
Water Extract ◽  
Coriandrum Sativum ◽  
Male Rats ◽  
Control Group ◽  
Control Group Design ◽  
White Rats ◽  
Wistar Strain ◽  
Sugar Levels

AbstractBackground : Diabetes mellitus is the most common metabolic syndrome in the whole world with an incidence of 1-8%. This disease arises when insufficient insulin is produced or insulin cannot function properly.The ability of coriander juice water extract is expected to reduce blood glucose levels because the action is similar to insulin and can stimulate insulin release. Purpose : Knowing effectiveness coriander extract (Coriandrum sativum L.)to decline blood sugar levels in male white rats (Rattus norvegicus L.) wistar strain induced by alloxan. Method : This is a pure experimental study (true-experiment) using a pre and post test design with control group design using subjects namely white rats (Rattus norvegicus L.) male Wistar strain aged 10-12 weeks with a weight of 150-200 grams. By looking at changes in blood sugar levels during administration of alloxan and administration of coriander extract. Results : There were significant changes in some groups induced alloxan (p <0.05), but the effect of coriander extract was not very significant (p> 0.05). Conclusion : Coriander extract can control blood sugar levels to be stable or normal, but it takes longer and more research.  Keywords : coriander extract, blood sugar levels, alloxan

scholarly journals EFEKTIVITAS PEMBERIAN TABLET TAMBAH DARAH DAN VITAMIN C TERHADAP KADAR HEMOGLOBIN IBU HAMIL DI WILAYAH KERJA UPT BLUD PUSKESMAS MENINTING

2020 ◽  
Vol 8 (2) ◽  
pp. 162-170
Author(s):  
Annisa Dwi Zulqaidah ◽  
Baiq Iin Rumintang
Keyword(s):  
Vitamin C ◽  
Pregnant Women ◽  
Hemoglobin Level ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Equivalent Control ◽  
And Control ◽  
Prevalence Of Anemia ◽  
Average Hemoglobin

Background:Based on the results of Basic Health Research in 2013, the prevalence of anemia in pregnant women in Indonesia 37.1%. Prevalence of anemia in pregnant women in the working area of ​​UPT BLUD Meninting Health Center in 2017 amounted to 28.18 %. To increase the absorption of hemoglobin levels, iron supplementation needs to be combined with other micronutrients such as vitamin C Objective:To know the effectiveness of giving tablets added blood and vitamin C to the hemoglobin level of pregnant women Method:This research used Quasi Experiment with Non Equivalent Control Group design with 30 samples divided into intervention and control group Results:The characteristics of pregnant women found that most of them were 20-35 years old (83,3%), high school education (56,7%), respondents who did not work or housewives (96,7%), respondents multiparas (70%), the distance of pregnancy >5 years (61,9%). The average hemoglobin levels of pregnant women who only get tablets added blood 0.36 gr/dL. The average hemoglobin levels of pregnant women who get tablets added blood and vitamin C amounted to 1.2 gr/dL. Statistical test results independent t test obtained p value of 0.006 Conclusion:There is effectiveness of giving tablets added blood and vitamin C to pregnant woman's hemoglobin level

scholarly journals Tamarillo Juice (Solanum betaceum Cav) as An Alternative to Increase Hemoglobin Levels for Pregnant Women with Anemia

2021 ◽  
Vol 2 (3) ◽  
pp. 106-119
Author(s):  
Juana Linda Simbolon ◽  
Emilia Silvana Sitompul
Keyword(s):  
Treatment Group ◽  
Pregnant Women ◽  
Hemoglobin Level ◽  
World Health ◽  
Control Group ◽  
Control Group Design ◽  
Test Analysis ◽  
Post Test ◽  
Quasi Experimental ◽  
Average Hemoglobin

Introduction: World Health Organizations recommends pregnant women to consume 120-240 mg of iron (in the form of Ferrum) per day and increase the dose by 400 mg 3 times a day if the Anemia is severe. One of the herbal therapies that can increase hemoglobin levels is Tamarillo (Solanum Betacum Cav) with a vitamin C level of 25 mg, Fe 2,765 ppm. The research objective was to analyze the effect of Tamarillo juice consumption in increasing hemoglobin (HB) levels of pregnant women with Anemia. Methods: Quasi-experimental research with pre and post-test along with control group design was used to compare the HB levels of ≥ 32 weeks pregnant women who were given Tamarillo fruit juice. Subjects in this study were 34 pregnant women as the treatment group who received Tamarillo juice and blood supplement and the control group of pregnant women who only receive blood supplements. Results: The results of the T-test analysis showed that in the treatment group there was an increase in the average hemoglobin level of 0.91 g/dL in the first week and 1.75 g/dL in the second week, while in the control group there was an increase in the average hemoglobin level of 0.43 g/dL in the first week and an increase of 0.89 g/dL in the second week. Conclusion: The administration of Tamarillo juice as an alternative companion to blood supplement in the prevention and management of care for pregnant women with Anemia.

Efektivitas Lidah Buaya (Aloe Vera) Dan Daunsirih (Piper Betle Linn) Terhadap Kesembuhan Luka Bakar Derajat Ii Pada Tikus Putih (Rattus Norvegicus Strain Wistar) Di Peternakan Tikus Sidomulyo Kediri

1970 ◽  
Vol 5 (1) ◽  
pp. 114
Author(s):  
Putri Kristyaningsih
Keyword(s):  
Burn Injury ◽  
Wound Care ◽  
Aloe Vera ◽  
Male Rats ◽  
Control Group ◽  
P Value ◽  
Piper Betle ◽  
Control Group Design ◽  
White Rats ◽  
Grade Ii

Background: Second grade burn injuryis burns which includes the destruction of epidermis and upper layers of the dermis and injury in the deeper dermis. Smear use aloe vera and betel leafs, it is an non-pharmacological methods that can accelerate the burn injury healing. Objectives: Determine the effectiveness of aloe vera and betel leafs to the healing of grade II burn injury on white rat in Kediri Sidomulyo livestock. Methods: This research uses a True Experimental, with post test only control group design. The sample in this study were 18 male rats, selected using Sample Random Sampling. Theburns injury made by inducing an iron plate (1x1 cm2) that already heated with boiling water for 5 minutes then stick it on the backs of rat for 30 seconds (area of ​​the epidermis). Data collected using observation sheet, ofusing burn injury woundcare observational sheet. Results: Using ANOVA The results of this study showed that the p value = 0.000, which means that H1 is accepted. Conclusions and Suggestion: There are differences in healing burns secondgrade by using a smear of betel leaf and aloe vera on white rats. This study can be recommended as the development of science in medical-surgical nursing for wound care is more effective and faster in accelerating the healing of burn injury.;Key Words :Grade II Of Burn Injury, Aloe Vera, Betel Leafs, White Rats

scholarly journals Efek anthiperkolesterol snack bars beras ketan hitam (Oryza sativa var. glutinosa) labu kuning (Cucurbita moschata) pada tikus Sprague dawley

2021 ◽  
Vol 26 (1) ◽  
pp. 37
Author(s):  
Akhmad Mustofa ◽  
Nanik Suhartatik ◽  
Ratna Dewi Nugraheni
Keyword(s):  
Total Cholesterol ◽  
White Male ◽  
Male Rats ◽  
Blood Cholesterol ◽  
Control Group ◽  
Sprague Dawley ◽  
Control Group Design ◽  
White Rats ◽  
Glutinous Rice ◽  
Pumpkin Powder

Snack bars from black glutinous rice and yellow pumpkin powder has been developed. The aim of the research was to evaluate the effect of the snack bars to the lipid profile of white male rats Sprague dawley. The experimental design of the research was Pre-Post Test Randomized Control Group Design using 25 male white rats. The rats were divided randomly into 5 groups, which was Group 1 as negative control (standard feed), Group 2 as positive control (feed with lard for hyper cholesterolemia condition, Group 3 was treated with simvastatin (0.18 mg / 200gBB), Group 4 treated with snack bars A (450mg / kgBB) and Group 5 was treated with snack bars B (450mg / kg BB). The differences between snack bar A and B were the proportion of black glutinous rice and yellow pumpkin powder. The snack bar was given orally. Total cholesterol, HDL, LDL, and triglycerides after 14 days of the treatment. According to the statistical analysis (p<0.05), the results showed that group with simvastatin has no significant differences with group with snack bars A.  Group with simvastatin, snack bars A, and snack bars B significantly influence blood cholesterol levels, total cholesterol, triglyceride levels, and LDL levels.  Mainly, snack bars A could decline blood cholesterol as good as simvastatin. Snack bars A have a higher portion of black glutinous rice than snack bars B.

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