scholarly journals Clinical morphological reasoning of the diagnosis of subclinical cows endometritis

2021 ◽  
Author(s):  
N.A. Slesarenko ◽  
E.O. Shirokova ◽  
A.P. Belyakova
Keyword(s):  
Structural Changes ◽  
Methodological Approach ◽  
Live Weight ◽  
External Genitalia ◽  
The Body ◽  
Reproductive Age ◽  
Digital Data ◽  
Clinical Indicators ◽  
Acute Form ◽  
Subclinical Endometritis

The project presents the results of the clinical and morphological substantiation of the diagnosis of endometritis in cows. The scientific and production part of the experiment was carried out by the method of selection of analog groups, taking into account the reproductive age and live weight, according to generally accepted methods. Two groups of animals were formed. Group one - cows with subclinical endometritis, group two - with no signs of this pathology, which is morphological control. Of these, seven animals were healthy and thirteenth with signs of endometritis. Of these, pathology in an acute form was detected in three animals, in a latent form in ten animals. The formation of a group of animals with a normal course of the postpartum period was carried out on the basis of techniques, including examination of the external genitalia and rectal examinations. General clinical indicators were also taken into account: temperature, pulse and respiration. The studies were carried out on the basis of the Department of Anatomy and Histology of Animals named after Professor A.F. Klimov FGBOU VO MGAVMiB - MBA named after K.I. Scriabin, as well as in ZAO Povadino breeding plant. Hematological studies were carried out on the basis of the Chance Bio laboratory. A comprehensive methodological approach was used in the work, including clinical examination of animals, macroscopic morphometry, anatomical preparation, morphological blood tests, statistical analysis of the obtained digital data. The normative morphological parameters of the uterus in black-white Holsteinized cows were established as the baseline for assessing the nature of structural changes in the organ with subclinical endometritis. Revealed pathognomonic morphological signs of the uterus in subclinical endometritis, expressed in an increase in its cavity and horns, the accumulation of exudate in them, in the swelling and dullness of the endometrium. In the course of the conducted hematological studies, the manifestation of an inflammatory reaction was noted, expressed in an increase in the number of leukocytes, stab and segmented neutrophils and monocytes. The article presents the clinical and morphological substantiation of the diagnosis of subclinical endometritis, based on a comprehensive assessment of changes in the morphometric parameters of the uterus and hematological changes occurring in the body.

scholarly journals MORPHOLOGICAL FEATURES OF THE GENERAL COVER IN SHORT-HAIRED FELINE BREEDS

2021 ◽  
Vol 6 (1) ◽  
pp. 38-44
Author(s):  
Natal'ya Slesarenko ◽  
Polina Zagorec
Keyword(s):  
Morphological Changes ◽  
Methodological Approach ◽  
Reproductive Age ◽  
Digital Data ◽  
Skin Damage ◽  
Skin Change ◽  
Anatomical Dissection ◽  
Damage Repair ◽  
Animal Anatomy

The aim of the research is characterization of the skin change of the feline family, depending on the breed charac-teristics of the animals. Clarification of relations, breed-specific features of skin of representatives of the felines fam-ily in order to establish the predominant for the development of dermatotropic pathologies is one of the urgent tasks of clinical morphology and dermatology. The general regularities and breed features of the skin cover of short-haired cat were established, taking into account its regional anatomical and physiological features. The inverse relationship between the epidermis thickness and the density of the hair cover of the studied animals was revealed, regardless of the breed identity. A specific glomerate collagen morphology of dermis was found typical for all cats of short-haired breeds. The research was carried out at the Department of Animal Anatomy and Histology named after Professor A. F. Klimov, Moscow State Academy of Veterinary Medicine and Biotechnology after Scriabin, MBA. The object of the study involved 27 individuals of short-haired cats of reproductive age (2-5 years), including Siamese (n=5), Russian blue (n=5), Burmese (n=6), British short-haired (n=7), Bengal (n=4). The research material is the skin. A comprehensive methodological approach was used, including anatomical dissection, light microscopy of histologi-cal sections, micro-morphometry, and statistical analysis of the obtained digital data. The results obtained are the basic for assessing the morphological and functional skin state and identifying morphological changes that occur in the conditions of skin damage repair.

scholarly journals STRUCTURAL CHANGES IN PROSTATE OF REPRODUCTIVE AGE RATS UNDER IMMUNOSUPPRESSION

2018 ◽  
Vol 35 (3) ◽  
pp. 79-86
Author(s):  
S A Kaschenko ◽  
A A Zakharov
Keyword(s):  
Epithelial Cells ◽  
Body Mass ◽  
Structural Changes ◽  
Microscopic Level ◽  
The Body ◽  
Reproductive Age ◽  
Cell Nuclei ◽  
Experimental Animals ◽  
White Rats ◽  
Level Height

Aim. To establish the structural changes in the prostate of reproductive experimental animals in conditions of long immunosuppression. Materials and methods. Sixty white rats of reproductive age were studied. The state of immunosuppression was modeled with intramuscular introduction of cyclophosphamide in the dose of 1.5 mg/kg of the body mass during 10 days. Linear sizes and volume of the organ were determined. At the microscopic level, height and width of epithelial cells, their volume as well as large and small diameters and cell nuclei volumes were determined. Results. In response to long immunosuppressive impact, organometric indices of the prostate both in the early (on days 7, 15) and late (on day 30) observation periods decreased owing to indirect cytotoxic impact of cyclophosphamide on the glandular and stromal components of the organ. Conclusions. The decreased values of linear-volumetric micromorphometric indices within the same observation periods confirm the dynamics of organometric parameters of the gland and prove intensive response of the organ at micro-and-submicroscopic level.

Influence of DAFS-25+polizon composition on blood and functional state of liver of steers at fattening

2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  
Keyword(s):  
Functional State ◽  
White Blood Cells ◽  
Live Weight ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Standard Diet ◽  
The Impact ◽  
Experimental Group ◽  
Stimulation Of

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.

HISTOLOGICAL CHANGES IN THE INTESTINES OF POULTRY DURING FODDER INTOXICATION

2020 ◽  
Author(s):  
E.P. Dolgov ◽  
◽  
A.A. Abramov ◽  
E.V. Kuzminova ◽  
E.V. Rogaleva ◽  
...  
Keyword(s):  
Body Weight ◽  
Histological Examination ◽  
Aflatoxin B1 ◽  
Structural Changes ◽  
Clinical Manifestations ◽  
Feed Additives ◽  
The Body ◽  
Histological Changes ◽  
Beet Pulp

The article presents the data on the study of the influence of mycotoxins combination (T-2 toxin at the concentration of 0.095 mg/kg and aflatoxin B1 in the concentration of 0.019 mg/kg) on the body of quails and the results of pharmacocorrection of toxicosis with a complex consisting of beet pulp and lecithin. Structural changes in the intestines of quais at fodder mycotoxicosis are described. The use of antitoxic feed additives in poultry led to a weakening of the action of xenobiotics, which was confirmed by an increase in the safety of poultry and increase in body weight of quails, a decrease in the clinical manifestations of intoxication, as well as in positive changes in the structure of the intestine of the poultry during histological examination.

Factor Related With the Anemia Incidence Of Adolescent Girl in Private High School Santa Lusia Medan, 2019

2020 ◽  
Vol 4 (2) ◽  
pp. 33
Author(s):  
Risda Mariana Manik ◽  
Hetty Gustina Simamora
Keyword(s):  
High School ◽  
Adolescent Girl ◽  
Sampling Technique ◽  
Consumption Patterns ◽  
Reproductive Age ◽  
Digital Data ◽  
Deficiency Anemia ◽  
Consumption Pattern ◽  
Cross Sectional ◽  
Private High School

According to data Basic Healt Research (Riskesdas) in 2016, as many as 22,7% women of reproductive age more than 15 years indicate anemia. Anemia that often occurs is iron deficiency anemia, the incidence reaches 50% of the total anemia. There is a significant relationship between nutritional status and incidence of anemia in adolescent.This study was an observational analytic with a cross sectional approach. This study was conducted in private high school Santa Lusia Medan. The population of this study were adolescent girl with a total sample 74 using total sampling technique. The research material in the form scales and height measurements to measure boddy mass index, quesioner for iron consumption patterns and consumption habits of Fe tablet and hemoglobin levels were examined using haemometer digital. Data analysis used chi square test (α=0,005).The results of the research are variabels related to anemia incidence are body mass index (sig=0,019), iron consumption patterns (sig=0,017), Fe tablet consumption habit (sig=0,045). Conclusion this study is factor causing anemia in adolescent girls is the pattern of iron consumption. Adolescent girl who have irreguler iron consumption pattern have an oppurtunity to experience anemia of 4,250 compared to adolescent girl who have reguler iron consumption patterns.

Local mineral feed additives in the rations of steers of Hereford breed

2020 ◽  
pp. 28-39
Author(s):  
M. Grigoryev ◽  
N. Chernogradskaya
Keyword(s):  
Economic Effect ◽  
Live Weight ◽  
Negative Influence ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Mineral Salts ◽  
Meat Productivity ◽  
Experimental Group ◽  
Mineral Feed Additives

Animals imported to Yakutia from other regions fall into feeding and housing conditions that differ from their usual agro-climatic conditions, which causes the problem of their adaptation. Yakutia is one of the areas where the feed of its own production has a lack of basic minerals, which affects the health and productivity of animals, which has an additional negative influence on the adaptation process of imported cattle. In order to replenish macro- and microelements in the body, it is necessary to introduce various local mineral feed additives, premixes, and use mineral salts into the ration. Under the conditions of Central Yakutia the influence of local mineral feed additives (zeolite of the Khonguruu Deposit in the Suntar district and sapropels of local lakes) containing macro- and microelements that increase the meat productivity of steers has been studied. As a result of the research the influence of local mineral feed additives on meat productivity and physiological condition of Hereford steers has been established. Influence of zeolite and sapropel in a complex with mineral salts on digestibility of nutrients of the ration and use of nitrogen, calcium and phosphorus by experimental animals has been defined. The influence of feed additives on the quality of meat products has been studied. The results have shown that the use of local mineral feed additives in the composition of ration of steers during the fattening period at a dose of 0,7 g zeolite per 1 kg of live weight of the animal and 200 g of sapropel in combination with 10 g of mineral salts contributed to the gain in live weight, carcass weight, carcass yield, yield of edible parts, and economic efficiency of fattening. For the entire period of the experiment the gain in live weight in groups was: in control group 2222,9 kg, in the 1st experimental group 2396,2 kg, in the 2nd experimental group 2471,1 kg. The total economic effect for the 1st experimental group for the period of experiment amounted to 44,3 thousand Rubles, for the 2nd experimental group 78,0 thousand Rubles or per 1 head/day 14,06 and 24,76 Rubles, respectively.

The effectiveness of use of enterosorbent Shelltic Es when rearing of young pigs

2020 ◽  
pp. 3-11
Author(s):  
S. Grikshas ◽  
N. Kulmakova ◽  
K. Spitsyna ◽  
A. Dar’in ◽  
T. Mittelshtein
Keyword(s):  
Average Daily Gain ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Internal Organs ◽  
Feed Digestibility ◽  
Young Pigs ◽  
Carcinogenic Effects ◽  
Experimental Group

Mycotoxins have been formed in feed are secondary metabolites of fungi and are quite stable substances that have teratogenic, mutagenic and carcinogenic effects. An effective way to combat mycotoxins in feed is the use of feed additives that adsorb toxins, prevent their absorption in the gastrointestinal tract of the animal and are excreted from the body. The infl uence of coconut enterosorbent Shelltic Es on fattening and meat qualities of young pigs has been studied. It has been found in the process of fattening that the highest feed digestibility was in pigs of the experimental group, in the diet of which enterosorbent has been added. The results of studies of the chemical composition and technological properties of pork have been provided. The positive eff ect of enterosorbent on precocity, absolute average daily gain of live weight and reduction of feed expenditures per 1 kg of gain has been revealed. In pigs from the experimental group the average thickness of the fat was higher and the area of the “muscle eye” was lower compared with animals of the control group, which indicates that higher rates of carcass yield have been obtained due to faster accumulation of fat tissue. The weight of internal organs of pigs indicates the intensity of metabolic processes in the body. In experimental animals the weight of the lungs was 0,1 kg lower, and the liver and heart were higher by 0,13 and 0,01 kg, respectively. Enterosorbent had no effect on the content of vitamins in the liver of pigs of the compared groups. The content of impurities of organochlorine toxicants and toxic elements in the meat and liver of animals of the experimental group was lower than that of control analogues. Therefore, the use of enterosorbent Shelltic Es promotes more active excretion of them from the body.

Indicators of metabolism and biochemical status of blood in horses of Yakut breed in winter and spring seasons

2020 ◽  
pp. 52-65
Author(s):  
U. Khompodoeva ◽  
R. Ivanov
Keyword(s):  
Classical Method ◽  
Live Weight ◽  
Weather Conditions ◽  
The Body ◽  
Metabolic Energy ◽  
Temperature Changes ◽  
Experimental Animals ◽  
Spring Period ◽  
Biochemical Status ◽  
Adaptive Mechanisms

The results of researches on the peculiarities of metabolism in the body of horses of Yakut breed in the winter and spring periods under the environments of Central Yakutia have been presented in the article. Physiological experiments on the digestibility of the main nutrients of the feed have been carried out in the winter (February) and spring (April) periods under the environments of the physiological yard in the Yakutsk Scientific and Research Institute of Agriculture named after M. G. Safronov with using the classical method. Five mares and five geldings of Yakut breed have been selected for researches. The average live weight of mares was 378–410 kg, geldings 394–403 kg. The experimental animals had average fatness. It has been found a higher intake of energy and the main nutrients of hay as a mono feed in winter compared to the spring period. At the same time pregnant mares in winter have been consumed 103,8±3,12 MJ of metabolic energy per head/day, which was 27,3 % significantly higher than in the spring period – 75,4±2,18 MJ (P ≥ 0,999). Geldings have been consumed in the experiment 67,70±2,85 MJ, which was by 43,7 % higher than in the spring period – 38,05 ± 4,40 MJ of metabolic energy per head/day (P ≥ 0,999). Experimental animals have been housed in stalls; there was no energy expenditure for movement, so the amount of energy consumed in winter indicates the production of heat in the animal’s body. Pregnant mares per 100 kg of live weight have consumed 31,5±4,11 MJ of metabolic energy or 33,3 % more than in the spring period – 21,0±1,98 MJ; geldings have consumed 27,69±1,12, which was 41,78 % significantly higher than in the spring – 16,12 ± 0,75 MJ (P ≥ 0,999). The high intake of metabolic energy into the body of Yakut horses in winter is explained by the manifestation of adaptive mechanisms that affect the effective metabolism for survival, adapted to frequent changes in weather conditions and sharp temperature changes. The established differences in the biochemical parameters of blood serum of horses of Yakut breed are associated with changes in the consumption and digestibility of basic nutrients and energy, depending on the ambient temperature.

Influence of Ascorbic Acid on the Structure and Function of Alpha-2- macroglobulin: Investigations using Spectroscopic and Thermodynamic Techniques

2020 ◽  
Vol 27 (3) ◽  
pp. 201-209
Author(s):  
Syed Saqib Ali ◽  
Mohammad Khalid Zia ◽  
Tooba Siddiqui ◽  
Haseeb Ahsan ◽  
Fahim Halim Khan
Keyword(s):  
Ascorbic Acid ◽  
Conformational Changes ◽  
Structural Changes ◽  
The Body ◽  
Titration Calorimetry ◽  
Spectroscopic Techniques ◽  
Human Beings ◽  
Plasma Ascorbic Acid ◽  
Dietary Antioxidant ◽  
And Function

Background: Ascorbic acid is a classic dietary antioxidant which plays an important role in the body of human beings. It is commonly found in various foods as well as taken as dietary supplement. Objective: The plasma ascorbic acid concentration may range from low, as in chronic or acute oxidative stress to high if delivered intravenously during cancer treatment. Sheep alpha-2- macroglobulin (α2M), a human α2M homologue is a large tetrameric glycoprotein of 630 kDa with antiproteinase activity, found in sheep’s blood. Methods: In the present study, the interaction of ascorbic acid with alpha-2-macroglobulin was explored in the presence of visible light by utilizing various spectroscopic techniques and isothermal titration calorimetry (ITC). Results: UV-vis and fluorescence spectroscopy suggests the formation of a complex between ascorbic acid and α2M apparent by increased absorbance and decreased fluorescence. Secondary structural changes in the α2M were investigated by CD and FT-IR spectroscopy. Our findings suggest the induction of subtle conformational changes in α2M induced by ascorbic acid. Thermodynamics signatures of ascorbic acid and α2M interaction indicate that the binding is an enthalpy-driven process. Conclusion: It is possible that ascorbic acid binds and compromises antiproteinase activity of α2M by inducing changes in the secondary structure of the protein.

Fournier’s gangrene due to Salmonella Typhimurium in a healthy male: a rare aberrant infection

2020 ◽  
Vol 20 ◽  
Author(s):  
Varsha Gupta ◽  
Lipika Singhal ◽  
Kritika Pal ◽  
Mani Bhushan ◽  
Rajeev Sharma ◽  
...  
Keyword(s):  
Salmonella Typhimurium ◽  
Systemic Disease ◽  
External Genitalia ◽  
Fournier’S Gangrene ◽  
The Body ◽  
Healthy Male ◽  
Fournier's Gangrene ◽  
Salmonella Infections ◽  
Chief Complaints ◽  
Human Infections

Introduction: Human Salmonella infections have been classically distinguised into diseases caused by typhoidal and non-typhoidal salmonella (NTS). Typhiodal salmonella includes S. enterica serovars Typhi and Paratyphi that cause the systemic disease but are restricted to human infections, while NTS consists mainly of other serovars that predominantly cause self-limiting gastroenteritis in humans. Localisation of foci with persisting infection occurs due to dissemination of the bacteria throughout the body and can cause a variety of rare clinical syndromes at aberrant sites. Fournier’s gangrene, a rapidly progressive, often fatal, necrotizing fasciitis of the external genitalia and perineum due to Salmonella Typhimurium, is a rare manifestation and has never been reported. Case: A 22-year-old male, apparently healthy patient with no relevant past medical history presented to surgical emergency with chief complaints of swelling of bilateral scrotal area. Infective etiology was considered and a diagnosis of fournier’s gangrene was made. Pure growth of Salmonella Typhimurium was obtained after repeated subculture and was identified biochemically and on serotyping, as Salmonella enterica serotype Typhimurium using specific antisera. Conclusion: In our case report, we describe a case of fournier’s gangrene due to Salmonella Typhimurium in an otherwise healthy male to highlight the unusual presentation of Non typhoidal salmonellae at an aberrant site. We also emphasize the importance of using selective media like Selenite F broth for isolation of Salmonella Typhimurium from a pus sample.

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