The duration of labor activity of workers in the production of phthalic anhydride and the imbalance of cellular immunity indicators

2021 ◽  
Vol 61 (2) ◽  
pp. 97-102
Author(s):  
Dina G. Dianova ◽  
Oleg V. Dolgikh
Keyword(s):  
Phthalic Anhydride ◽  
Work Experience ◽  
Dynamic Monitoring ◽  
Production Factor ◽  
Observation Group ◽  
Chemical Production ◽  
Associated Production ◽  
Production Factors ◽  
Study Results ◽  
Professional Contact

Introduction. The phthalic anhydride, which widely used in chemical industry in conditions of chronic ingestion, chronically leads to a disadaptation of immunity, which is a risk factor in the formation of associated production related pathology. The aim of the work is to study the subpopulation profile of lymphocytes and cytokine status in workers engaged in the production of phthalic anhydride with their work experience. Materials and methods. The observation group, totally 68 men, consisted of employees working at the main phthalic anhydride production facility. The workers of the observation group were divided into two subgroups with their work experience at the enterprise: 44 persons with 0 to 10 years of work experience and 24 persons with more than 10 years of work experience. The comparison group - 40 men who had no professional contact with harmful production factors. The chemical-analytical, cytofluorimetric, immunoenzyme methods use during the study. Results. The workers being exposed to phthalic anhydride with up to 10 and more than 10 years of work experience at the enterprise have a phthalic acid content in their blood that is 2.3 and 3.3 times higher, respectively than related to persons who are not in contact with the analyzed harmful production factor (p=0.002-0.033). It was found that longtime workers, engaged in the production of phthalic anhydride, manifested the immune response cellular link dysfunction. Workers employed in the main production of phthalic anhydride with more than 10 years of work experience revealed a prevalence of activation processes (according to CD25+ criterion), inhibition of cytotoxic cell-mediated response (according to CD3+CD16+CD56+ criterion), gyperexpression of Th2-cytokines (according to criterion IL4) relative to values obtained from workers of the production with less than 10 years of work experience in hazardous production conditions (p=0.002-0.033). Conclusions. The duration of employment of the workers, contacting with excessive concentrations of phthalic anhydride in workplace air, contributes to negative dynamics in the imbalance between T-cells and cytokine products. The dynamic monitoring of immunoregulatory indicators in workers occupied in the production of phthalic anhydride will contribute to just-in-time revealing of the immune system violations in order to reduce the risks of formation of associated production-related pathology induced by the chemical production factors.

Changes in biochemical parameters in workers exposed to chemical production factors (heptane and hexane)

2021 ◽  
Vol 61 (6) ◽  
pp. 379-384
Author(s):  
Marina A. Zemlyanova ◽  
Juliya V. Koldibekova ◽  
Ekaterina V. Peskova ◽  
Victor M. Ukhabov
Keyword(s):  
Blood Serum ◽  
Blood Plasma ◽  
Biochemical Parameters ◽  
Comparison Group ◽  
Processing Plant ◽  
Observation Group ◽  
Chemical Production ◽  
Production Factors ◽  
Nasal Secretions

Introduction. Long-term constant exposure to certain representatives of aliphatic hydrocarbons during the extraction and processing of potash ore can lead to pathological changes on critical organs and systems in production workers. The study aims to evaluate the change in biochemical parameters in workers exposed to chemical production factors (heptane and hexane). Materials and methods. The study of the content of hexane, heptane in the air of the working area and the urine of workers, the establishment of changes in several biochemical (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, glutamyltransferase, epinephrine, and norepinephrine) and general clinical (eosinophils, neutrophils and the eosinophilia index) indicators, modeling of cause-and-effect relationships. Results. Specialists found in the observation group relative to the comparison group: increased levels of heptane and hexane in the urine up to 1.7 times; increased levels of adrenaline and norepinephrine in the blood plasma up to 1.8 times, up to 1.4 times ALAT and γ-GT in the blood serum, up to 1.9 times neutrophils in the nasal secretions associated with increased concentrations of heptane and hexane in the urine; an increase of up to 4.4 times in the frequency of diseases of the nervous system, respiratory organs, and digestion. Conclusions. In the air of the working area of the workers of the flotation shop of the sylvinite processing plant, the concentrations of the studied limit hydrocarbons were below the detection limit; there is an increased concentration of heptane and hexane in the urine. In the workers of the studied production, an increase of 1.4-1.8 times in the level of adrenaline and norepinephrine in blood plasma, 1.2-1.4 times in ALAT and γ-GT in blood serum, 1.9 times in the content of neutrophils in nasal secretions, which characterizes adverse effects from the respiratory, digestive and nervous systems. We proved the dependence of the increased frequency of diseases of the listed organs and systems on the increased concentration of heptane in the urine (R2=0.26-0.43; p=0.0001-0.028).

Arterial hypertension and cardiovascular risk factors in employees of underground mining ore minerals

2019 ◽  
pp. 945-949 ◽  
Author(s):  
A. S. Baydina ◽  
N. V. Zaitseva ◽  
V. G. Kostarev ◽  
O. Yu. Ustinova
Keyword(s):  
Risk Factors ◽  
Arterial Hypertension ◽  
Clinical Features ◽  
Work Experience ◽  
Comparison Group ◽  
Underground Mining ◽  
Observation Group ◽  
Permanent Disability ◽  
Production Factors ◽  
The Impact

Introduction. The wide spread of mining in Russia determines the high relevance of the preservation of labor resources in this industry, the prevention of occupational and production-related morbidity, reducing cases of temporary and permanent disability. Mine mining is characterized by the impact on workers of several nonspecific harmful (dangerous) factors: industrial noise, general and local vibration, the severity of labor, heating or cooling microclimate, low light. The impact of these factors predisposes to the development of pathology of the cardiovascular system.The aim of the study was to study the prevalence of hypertension among underground miners, clinical features and changes in the complex of biochemical risk factors for cardiovascular complications.Materials and methods. The observation group consisted of 98 employees of underground chrome ore mining. The comparison group (working in conditions outside the influence of the studied production factors) consisted of 75 employees of this enterprise. All employees surveyed are male. To study the impact of working conditions on the health of workers, workplaces with a characteristic set of harmful production factors (chrome, dust, noise, vibration, labor severity, labor intensity, cooling microclimate) and the same working modes (sliding three-shift schedule with a shift duration of eight hours) were selected. The study of laboratory parameters (markers of risk of cardiovascular disease) was performed by unified General clinical, biochemical and enzyme immunoassay methods.Results. In the group of underground miners, the prevalence of arterial hypertension was established (in 31.3% in the observation group and in 17.2% of the surveyed in the comparison group, p=0.042), which becomes statistically significant when the work experience is more than 10 years. The study established the clinical features of the anamnesis and objective status of employees of the mine for the extraction of chrome ore. The laboratory study in the group of miners revealed the presence of a number of paraclinic syndromes: systemic inflammation and immune activation syndrome, dyslipidemia syndrome, oxidative stress syndrome, hormonal profile disorder, renal dysfunction syndrome.Conclusions. Employees of underground mining of chrome ore are characterized by a high incidence of hypertension with experience of more than 10 years. The clinical and instrumental changes revealed in the work in the observation group give grounds for the development of directed preventive programs in this category of ore mine workers.

Oil Prices: Limits to Growth and the Depth of Falling

2006 ◽  
pp. 28-41 ◽  
Author(s):  
I. Bashmakov
Keyword(s):  
Energy Demand ◽  
Negative Relationship ◽  
Oil Prices ◽  
Production Factor ◽  
Energy Costs ◽  
Purchasing Power ◽  
Limits To Growth ◽  
Technological Basis ◽  
Production Factors ◽  
Output Ratio

This article deals with the determination of future oil prices. The approach used is based on the evaluation of purchasing power limits and allows to put the limits to monopolistic price setting. Several important findings are formulated: going beyond the upper thresholds of purchasing power stipulates negative relationship between energy costs and GDP growth rates, and this brings the dynamics to energy demand to price elasticity. This approach is also based on what the author calls the economics of constants and variables, i.e. on the existence of very stable macroeconomic proportions, which may be observed throughout the whole period of statistical observations (over 200 years). It provides grounds for two conclusions. First, the upper limit of energy costs to the gross output ratio is determined by the least acceptable profitability. Second, the theoretical postulate on substantial production factors substitution used in the production functions theory may be incorrect. In reality, the change of the economy technological basis leads to the substitution of low quality production factor by the same factor with a higher quality. Application of this approach brings the basis for predicting oil prices for 2006-2008.

Assessment of cellular immunity in oil production operators with an imbalance of lipid metabolism

2020 ◽  
Vol 60 (11) ◽  
pp. 717-719
Author(s):  
Inga N. Alikina ◽  
Olga A. Kazakova
Keyword(s):  
Lipid Metabolism ◽  
Humoral Immunity ◽  
Cellular Immunity ◽  
Comparison Group ◽  
Oil Production ◽  
Observation Group ◽  
Immunological Parameters ◽  
Production Factors ◽  
Cellular And Humoral Immunity ◽  
Atherosclerotic Process

Introduction. Studies indicate the high pathogenetic significance of the immune component in the development of atherosclerosis. The aim of the study is a comparative assessment of immunological parameters in workers of petrochemical production with varying degrees of imbalance in lipid metabolism and the development of the atherosclerotic process. Materials and methods. Men working at an oil production enterprise in the Perm Region were examined. The observation group consisted of oil production operators with a diagnosis of atherosclerosis, the comparison group - with dyslipidemia syndrome. To determine the parameters of lipid metabolism, the results of a biochemical blood test were used. CD-immunogram parameters were identified by flow cytometry. Specific antibodies to benzene were determined by the allergosorbent method. Results. The results of a comparative study of fat metabolism confirmed violations of the physiological ratio of lipids in the blood of oil production workers, which were expressed in a significant imbalance in the levels of lipidogram. There was an increased level of specific IgG antibodies to benzene in the observation group in relation to the comparison group. An imbalance of cellular immunity was found, which was characterized by signs of indicators activation of cellular differentiation clusters. Conclusions. Studies of immune system compartments demonstrate excessive activation of cellular and humoral immunity in oil production workers under the influence of a combination of harmful production factors. The simultaneously formed imbalance of lipid metabolism is associated with various degrees of clinical manifestation of atherosclerotic disorders, with the influence of harmful production factors, aggressiveness of cellular and humoral immunity, and smoking.

Features of the long-term dynamics of heart rate variability among workers of a potash ore processing enterprise

2021 ◽  
Vol 61 (7) ◽  
pp. 442-450
Author(s):  
Alexandr E. Nosov ◽  
Nina V. Zaitseva ◽  
Vitalii G. Kostarev ◽  
Julia A. Ivashova ◽  
Maksim A. Savinkov ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Significant Relationship ◽  
Work Experience ◽  
Fine Particles ◽  
Comparison Group ◽  
Stress Index ◽  
Observation Group ◽  
Ore Processing ◽  
Processing Enterprise

Introduction. Currently, the violation of heart rate variability as one of the main pathogenetic mechanisms of the damaging effect of pollutants, associated effects on the cardiovascular system. The study aims to explore the dynamics of the influence of the autonomic nervous system (ANS) on heart rate variability (HRV) in workers of a potassium ore processing enterprise exposed to industrial pollutants (fine fractions of potassium chloride dust, formaldehyde, hexane, heptane) with an assessment of changes in dependence from work experience, establishment of cause-and-effect relationships of violations of heart rate variability with exposure to chemical compounds. Materials and methods. The object of the study was 140 employees of a potash ore processing enterprise, assigned to the observation group, and 76 employees of the administrative and technical apparatus, who made up the comparison group. Samples were taken from the air of the working medium for the content of saturated hydrocarbons (hexane, heptane), the vapors of formhehyde were considered, and the presence of fine particles PM2.5 and PM10 was established. Investigation of biological media (blood, urine) of workers at the enterprise determination of formaldehyde in blood, hexane and heptane in urine. Evaluation of heart rate variability was carried out on a computer electrocardiograph "Poli-Spectr-8/EX" using a cardiorhythmographic program using the method of time analysis, variation pulsometry and spectral analysis. Results. The concentration of fine particles in the air at the workplaces of the observation group was 12-111 times higher for PM2.5, and 5.6-74.6 times higher for PM10 than for the work places of the comparison group. The concentration of formaldehyde, hexane and heptane in the air did not exceed hygienic standards. In the observation group relative to the comparison group, formaldehyde blood was 1.5 times (p<0.001), in the urine of hexane - 1.2 times (p=0.011), heptane - 1.3 times (p=0.046). It was found that with an experience of up to 10 years, formaldehyde in the blood of workers in the observation group was 1.4 times higher than that in the comparison group (p=0.011), with an experience of more than 10 years - 1.7 times (p=0.005). In the urine of workers in the observation group with work experience of up to 10 years, an excess of 1.3 (p=0.026) relative to the comparison group of hexane was found. HRV data analysis. With damage to the length of service in the observation group, there was a significant decrease in the temporal analysis indicators (SDNN, ms, RMSSD, ms, pNN50, %, CV, %), while in the comparison group, only the CV, % decrease was statistically significant; the values of IN conventional units, AMo, % significantly increased (p=0.03 and p=0.003, respectively). A statistically significant relationship was established between the likelihood of an increase depending on the content of heptane in urine (b0=0.22; b1=10.6; F=21.5; R2=0.09; p=0.0001) and formaldehyde in the blood (b0=0.02; b1=6.55; F=69.6; R2=0.25; p=0.0001) in the surveyed workers. Conclusions. Activation of central ergotropic and humoral-metabolic mechanisms, a tendency towards a decrease in parasympathetic influences. The method of logistic regression analysis established a statistically significant relationship between the probability of an increase in the stress index depending on the heptane content in the blood of the surveyed suppliers.

scholarly journals Monitoring and Analysis of Dynamic Characteristics of Super High-rise Buildings using GB-RAR: A Case Study of the WGC under Construction, China

2020 ◽  
Vol 10 (3) ◽  
pp. 808 ◽  
Author(s):  
Lv Zhou ◽  
Jiming Guo ◽  
Xuelin Wen ◽  
Jun Ma ◽  
Fei Yang ◽  
...  
Keyword(s):  
Wavelet Analysis ◽  
Dynamic Characteristics ◽  
Horizontal Displacement ◽  
Dynamic Monitoring ◽  
High Rise ◽  
The North ◽  
Study Results ◽  
Under Construction ◽  
East West

Accurate dynamic characteristics of super high-rise buildings serve as a guide in their construction and operation. Ground-based real aperture radar (GB-RAR) techniques have been applied in monitoring and analyzing the dynamic characteristics of different buildings, but only few studies have utilized them to derive the dynamic characteristics of super high-rise buildings, especially those higher than 400 m and under construction. In this study, we proposed a set of technical methods for monitoring and analyzing the dynamic characteristics of super high-rise buildings based on GB-RAR and wavelet analysis. A case study was conducted on the monitoring and analysis of the dynamic characteristics of the Wuhan Greenland Center (WGC) under construction (5–7 July 2017) with a 636 m design height. Displacement time series was accurately derived through GB-RAR and wavelet analysis, and the accuracy reached the submillimeter level. The maximum horizontal displacement amplitudes at the top of the building in the north–south and east–west directions were 18.84 and 15.94 mm, respectively. The roof displacement trajectory of the WGC was clearly identified. A certain negative correlation between the temperature and displacement changes at the roof of the building was identified. Study results demonstrate that the proposed method is effective for the dynamic monitoring and analysis of super high-rise buildings with noninvasive and nondestructive characteristics.

scholarly journals ANALISIS PENDAPATAN DAN FAKTOR PENENTU PRODUKSI KAKAO HASIL SAMBUNG SAMPING DI KABUPATEN KONAWE

2018 ◽  
Vol 7 (2) ◽  
pp. 72
Author(s):  
Rusdin Rusdin ◽  
Zainal Abidin
Keyword(s):  
Organic Fertilizer ◽  
Land Area ◽  
Average Productivity ◽  
Production Factors ◽  
Study Results ◽  
Cocoa Production ◽  
Cultivation Technology ◽  
Npk Fertilizer ◽  
Low Levels ◽  
Factors Of Production

Extensive cocoa plantations in Southeast Sulawesi at 2013 were approximately 245 624 ha, which consists of 177 996 ha of productive plants, 38.970 ha and 28.658 ha unproductive unproductive plants. Cocoa productivity in Southeast Sulawesi as a whole is 0.754 t/ha. The low productivity of cocoa was due to several factors, namely: the use of random seed, still high PBK pest attack, low levels of cultivation technology, as well as the age old cocoa plants. The study was conducted in March - June 2014 Andomesinggu village, district. Besulutu, Konawe. The study results showed that the average productivity of the cocoa plant side grafting 2-3 years amounted to 380 kg/ha, profit of Rp. 7.160.900, -. with the value of RC ratio  of 4.22, meaning farming in the district Konawe economically feasible to be developed. Variables land area is very significant in improving cocoa production and is positive. Similarly, production factors KCl fertilizer, organic fertilizer real berpengatuh to increase cocoa production. While the factors of production of NPK fertilizer, Urea, ZA and pesticides did not significantly decline in production (negative values).

scholarly journals The INFLUENCE OF PRODUCTION FACTORS TOWARD ECONOMIC GROWTH IN INDONESIA

2019 ◽  
Vol 4 (1) ◽  
pp. 44-46
Author(s):  
Wilson Bangun
Keyword(s):  
Economic Growth ◽  
Secondary Data ◽  
Least Square ◽  
Production Factor ◽  
Domestic Investment ◽  
Ordinary Least Square ◽  
Production Factors ◽  
The People ◽  
Data Production ◽  
Using Data

Economic growth as a mesurement and reflect of the people prosperity. Employee production factor have a better contribution if  to compare with capital and technology production factors on Indonesian economic growth. However, Indonesian workforce quality is lowest in ASEAN-5. The research methodology is using the Cobb-Douglas production function with the Ordinary Least Square (OLS), the using equation formulation: lnY = ln a + bi  +e. This research using data is secondary data: production factors using data of progressing of FDI and domestic investment, source of  the World Bank, 2004-2016; Employment is using data of progressing of Indonesia workforce,  sourced from the Biro Pusat Statistik Republik Indonesia, 2004-2016. The research results show that influence of the production factors toward Indonesia economic growth is strongly. This researchs aim to knowledge a large the contribution of production factors on Indonesian Economic growth.

scholarly journals Analisis Efisiensi dan Skala Ekonomis Pada Industri Kerajinan Anyaman Bambu Kecamatan Susut Kabupaten Bangli

2019 ◽  
Vol 8 (1) ◽  
pp. 1-14
Author(s):  
Taranitha Putri Wilanda ◽  
Surya Dewi Rustariyuni
Keyword(s):  
Work Experience ◽  
Sampling Method ◽  
Economies Of Scale ◽  
Secondary Data ◽  
Analysis Techniques ◽  
Production Factors ◽  
Scale Test ◽  
Secondary Data Sources ◽  
Craft Industry

This study aims to analyze; 1) simultaneously, and analyze the partial effect of the use of production factors labor, work experience and capital for various products of the bamboo weaved craft industry, 2) to investigate the economies of scale and 3) analyze the efficiency of production factors in the bamboo weaved handicraft industry in Kecamatan Susut, Kabupaten Bangli. The type of data in this study is quantitative and qualitative data with primary and secondary data sources. Respondents in this study amounted to 93 peoples, a sample of 1277 craftsmen and calculated using the Slovin's formula. The determination of the sample size in each village was determined by the disproportional stratified random sampling method. Data analysis techniques used in this research is the analysis techniques of Cobb-Douglass, economies of scale, and economic efficiency. The results showed that the variable labor (X1), work experience (X2), and capital (X3) simultaneously and partially had a positive and significant impact on the amount of production (Y) to the bamboo weaved craft industry in Susut District, Bangli Regency. Economies of scale test in a state of increasing return to scale, but partially still in a decreasing return to scale condition. The efficiency of the use of production factors has not been efficient.

scholarly journals EFISIENSI PENGGUNAAN FAKTOR PRODUKSI DAN PENDAPATAN USAHATANI TUMPANGSARI STROBERI-BAWANG DAUN DI DESA SERANG KECAMATAN KARANGREJA KABUPATEN PURBALINGGA

2021 ◽  
Vol 14 (1) ◽  
pp. 57
Author(s):  
Savira Kusumadewi ◽  
Djeimy Kusnaman ◽  
Irene Kartika Eka Wijayanti
Keyword(s):  
Function Analysis ◽  
Economic Value ◽  
Simple Random Sampling ◽  
Production Factor ◽  
Farm Income ◽  
Land Area ◽  
Production Factors ◽  
A Value ◽  
C Value ◽  
Seed Area

Strawberry (Fragaria sp.)  is a type of fruit that has high economic value. An to increase the income of strawberry farmers is by intercropping with leek. To understand the efficiency of the farming the by using production input. This research aims to 1) analyze the effect of the use of production factors, 2) analyze the level of efficiency in the use of production factors, and 3) to analyze the profit level of intercropping strawberries-leek in Serang Village, Karangreja District, Purbalingga Regency. There are 35 samples obtained using simple random sampling. The analysis was performed using the Cobb Douglass production function analysis, the NPM / BKM ratio and farm income analysis. The results of this research were the use of production factors, seed; area; labor; and insecticides partially affected the production of intercropping strawberries, while the production factors of chicken-husk fertilizer; NPK-Phonska fertilizer; other fertilizers; and fungicides had no effect on the production of intercropping strawberries. The production factors for seeds; labor; and insecticides have an NPM-BKM ratio value greater than one where the use of these inputs is not efficient. Meanwhile, the production factor for land area has an NPM-BKM ratio value of less than one where the use of these inputs is not efficient. R / C for cash costs was 4.61 and R / C for total costs was 1.09. The R / C value for both cash costs and total costs has a value greater than one, so the strawberry and leek intercropping farming in Serang Village can be said to be profitable.

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