scholarly journals The Relationship between Dissolution Behavior and the Toxicity of Silver Nanoparticles on Zebrafish Embryos in Different Ionic Environments

Nanomaterials ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. 652 ◽  
Author(s):  
Wang Lee ◽  
Eungwang Kim ◽  
Hyun-Ju Cho ◽  
Taejoon Kang ◽  
Bongsoo Kim ◽  
...  

A silver nanoparticle is one of the representative engineered nanomaterials with excellent optical, electrical, antibacterial properties. Silver nanoparticles are being increasingly used for medical products, water filters, and cosmetics, etc. However, silver nanoparticles are known to cause adverse effects on the ecosystem and human health. To utilize silver nanoparticles with minimized negative effects, it is important to understand the behavior of silver nanoparticles released to the environment. In this study, we compared toxicity behaviors of citrate-stabilized silver nanoparticles with polyethylene glycol coated silver nanoparticles in two different ionic environments, which are aquatic environments for developing zebrafish embryo. Depending on the composition of the ionic environment, citrate-stabilized silver nanoparticles and polyethylene glycol coated silver nanoparticles exhibited different behaviors in dissolution, aggregation, or precipitation, which governed the toxicity of silver nanoparticles on zebrafish embryos.

2021 ◽  
Vol 13 (1) ◽  
pp. 1-9
Author(s):  
Saba Qureyshi ◽  
Zaman Sajid

Chitosan/ Polyethylene glycol and silver nanoparticles based antibacterial coating has been synthesized and applied to cotton cloth using sonochemical technique. In addition to the synthesis of nanoparticles using Pyrus seed extract (Green synthesis), Chitosan and PEG compound has also been used to develop the coating in this research. The coating obtained with this compound possesses good antibacterial properties and results. The study shows that the coated fabrics and silver nanoparticles show highly potent antibacterial activity towards gram negative and gram-positive bacteria. A comparison of coating with single and multiple components is studied; specifically, a comparison of pure chitosan and polyethylene glycol coating with their blend is studied. Agar plate test is performed against pseudomonas aeruginosa, Acinetobacter baumannii and methicillin-resistant staphylococcus aureus (MRSA), and the proposed process is helpful in healthcare industry and specified applications.


2016 ◽  
Vol 18 (4) ◽  
pp. 110-116 ◽  
Author(s):  
Anna Pachla ◽  
Zofia Lendzion-Bieluń ◽  
Dariusz Moszyński ◽  
Agata Markowska-Szczupak ◽  
Urszula Narkiewicz ◽  
...  

Abstract Superparamagnetic iron oxide nanoparticles were obtained in the polyethylene glycol environment. An effect of precipitation and drying temperatures on the size of the prepared nanoparticles was observed. Superparamagnetic iron oxide Fe3O4, around of 15 nm, was obtained at a precipitation temperature of 80°C and a drying temperature of 60°C. The presence of functional groups characteristic for a polyethylene glycol surfactant on the surface of nanoparticles was confirmed by FTIR and XPS measurements. Silver nanoparticles were introduced by the impregnation. Fe3O4-Ag nanostructure with bactericidal properties against Escherichia coli species was produced. Interesting magnetic properties of these materials may be helpful to separate the bactericidal agent from the solution.


2019 ◽  
pp. 46-64 ◽  
Author(s):  
Vladimir V. Klimanov ◽  
Sofiya М. Kazakova ◽  
Anna A. Mikhaylova

The article examines the impact of various socio-economic and financial indicators on the resilience of Russian regions. For each region, the integral index of resilience is calculated, and its correlation dependence with the selected indicators is revealed. The study confirms the relationship between fiscal resilience and socio-economic resilience of the regions. The analysis of panel data for 75 regions from 2007 to 2016 shows that there are significant differences in the dynamics of indicators in different periods. In particular, the degree of exposure to the negative effects of the crises of 2008—2009 and 2014—2015 in non-resilient regions is higher than in resilient ones.


2017 ◽  
Vol 7 (2) ◽  
pp. 159
Author(s):  
Eva Krisna

“Batombe” is an oral tradition of the Nagari Abai society at Sangir Batanghari Subdistrict, South Solok District, West Sumatra Province. Batombe is exchanging rhymes (berbalas pantun) which is performed as an entertainment on the wedding party (baralek). Batombe is identical with Great House (Rumah Gadang) Nagari Abai which is a unique house because it is a long traditional custom house that has many rooms. It reaches 21 rooms. The rhymes in batombe tends to deliver a feeling of lilting so the singers often drift into the atmosphere of the show. Therefore, as part of community life, batombe often cause a negative effects for the singers soul. This paper describes various things, such as: who batombe singer is; the time to perform this activity; the relationship between batombe and Great House (Rumah Gadang) at Nagari Abai; and the negative effects caused by batombe for the singers. This paper based on the fact that in oral tradition there is a close relationship between text and the speakers and text with context (place, time and atmosphere), a multidisciplinary approach is used in this paper, such as historical, sociological, anthropological, and psychological approach. The method used is descriptive analysis method.AbstrakBatombe adalah tradisi lisan masyarakat Nagari Abai, Kecamatan Sangir Batanghari, Kabupaten Solok Selatan, Provinsi Sumatra Barat. Batombe adalah tradisi berbalas pantun yang dilakukan sebagai hiburan pada pesta pernikahan (baralek). Batombe identik dengan rumah gadang Nagari Abai yang unik, yakni rumah adat dengan ruangan yang sangat panjang hingga 21 ruangan. Pantun-pantun batombe cenderung menyampaikan perasaan yang mendayu-dayu sehingga para pedendangnya sering hanyut ke dalam suasana pertunjukan. Oleh sebab itu, sebagai bagian dari kehidupan masyarakat, seringkali batombe menyebabkan efek negatif bagi (kejiwaan) para pedendangnya. Tulisan ini mendeskripsikan berbagai hal, seperti penutur batombe, waktu untuk melakukan batombe, hubungan batombe dengan rumah gadang di Nagari Abai, dan efek negatif yang ditimbulkan batombe bagi pedendangnya. Tulisan ini bertolak dari kenyataan bahwa pada tradisi lisan terdapat hubungan erat, antara lain seperti teks dengan penutur dan teks dengan konteks (tempat, waktu, dan suasana). Pendekatan multidisipliner digunakan pada tulisan ini, yakni pendekatan historis, sosiologis, antropologis, dan psikologis. Metode yang digunakan adalah metode analisis deskriptif.


2020 ◽  
Vol 26 ◽  
Author(s):  
Jun-Jie Tang ◽  
Shuang Feng ◽  
Xing-Dong Chen ◽  
Hua Huang ◽  
Min Mao ◽  
...  

: Neurological diseases bring great mental and physical torture to the patients, and have long-term and sustained negative effects on families and society. The attention to neurological diseases is increasing, and the improvement of the material level is accompanied by an increase in the demand for mental level. The p75 neurotrophin receptor (p75NTR) is a low-affinity neurotrophin receptor and involved in diverse and pleiotropic effects in the developmental and adult central nervous system (CNS). Since neurological diseases are usually accompanied by the regression of memory, the pathogenesis of p75NTR also activates and inhibits other signaling pathways, which has a serious impact on the learning and memory of patients. The results of studies shown that p75NTR is associated with LTP/LTD-induced synaptic enhancement and inhibition, suggest that p75NTR may be involved in the progression of synaptic plasticity. And its pro-apoptotic effect is associated with activation of proBDNF and inhibition of proNGF, and TrkA/p75NTR imbalance leads to pro-survival or pro-apoptotic phenomena. It can be inferred that p75NTR mediates apoptosis in the hippocampus and amygdale, which may affect learning and memory behavior. This article mainly discusses the relationship between p75NTR and learning memory and associated mechanisms, which may provide some new ideas for the treatment of neurological diseases.


2021 ◽  
Vol 36 (2) ◽  
pp. 93-110
Author(s):  
Princy Philip ◽  
Tomlal Jose ◽  
Sarath KS ◽  
Sunny Kuriakose

Silver nanoparticles with 5–10 nm diameters are synthesised using Couroupita guianensis flower extract. The synthesised silver nanoparticles found to show good antimicrobial activity against gram negative and gram positive bacteria. Poly(methyl methacrylate) nanofibers with pristine, surface roughened and coaxial hollow forms are prepared by electrospinning. The structural and morphological properties of these pure and structurally modified poly(methyl methacrylate) nanofibers are evidenced by various analytical techniques. The antimicrobial studies of poly(methyl methacrylate) nanofibers having different architectures incorporated with silver nanoparticles are carried out. It is found that, all the three forms of poly(methyl methacrylate) nanofibers incorporated with silver nanoparticles show antibacterial properties against both gram positive and gram negative bacteria. Among these, surface roughened poly(methyl methacrylate) nanofibers incorporated with silver nanoparticles show highest antibacterial activity than the other two structural forms. The present study offers an alternative to the existing optical lenses. People especially those who suffer from eye problems can protect their eyes in a better way from infectious agents by wearing optical lens made from C. guianensis stabilised silver nanoparticles incorporated poly(methyl methacrylate) nanofibers than that made from pure poly(methyl methacrylate) nanofibers or films.


Healthcare ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 630
Author(s):  
Satoshi Shimo ◽  
Yuta Sakamoto ◽  
Takashi Amari ◽  
Masaaki Chino ◽  
Rie Sakamoto ◽  
...  

Chronic pain and fatigue have negative effects on the health, ADL, work, and hobbies of the elderly. As the proportion of people 65 years of age and older in the population increases, chronic pain and disability research regarding this group is receiving more consideration. However, little empirical evidence of the association between chronic pain, fatigue, and physical disability between the sexes is available. This study investigated the association between chronic pain, fatigue, and instrumental activities of daily living among community-dwelling elderly people by sex in Japan. Concerning the presence of chronic pain, 61% of males and 78% of females reported chronic pain, indicating that many elderly people living in the community suffer from chronic pain and fatigue on a daily basis. The number of sites of chronic pain was higher in females than in males (p = 0.016), with more chronic pain in the knees (p < 0.001) and upper arms (p = 0.014). Regarding chronic pain, males showed a higher correlation with QuickDASH-DS (rs = 0.433, p = 0.017) and QuickDASH-SM (rs = 0.643, p = 0.018) than females. Furthermore, fatigue also showed a higher correlation with QuickDASH-W (rs = 0.531, p = 0.003) in males than in females. These results indicate that the association between chronic pain, fatigue, and QuickDASH differed between the sexes among community-dwelling elderly people in Japan. A better understanding of the risk factors for elderly chronic pain and fatigue among sexes will facilitate the development of elderly healthcare welfare and policies.


Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 678
Author(s):  
Abdallah S. Abdelsattar ◽  
Rana Nofal ◽  
Salsabil Makky ◽  
Anan Safwat ◽  
Amera Taha ◽  
...  

The emergence and evolution of antibiotic-resistant bacteria is considered a public health concern. Salmonella is one of the most common pathogens that cause high mortality and morbidity rates in humans, animals, and poultry annually. In this work, we developed a combination of silver nanoparticles (AgNPs) with bacteriophage (phage) as an antimicrobial agent to control microbial growth. The synthesized AgNPs with propolis were characterized by testing their color change from transparent to deep brown by transmission electron microscopy (TEM) and Fourier-Transform Infrared Spectroscopy (FTIR). The phage ZCSE2 was found to be stable when combined with AgNPs. Both minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated for AgNPs, phage, and their combination. The results indicated that MIC and MBC values were equal to 23 µg/mL against Salmonella bacteria at a concentration of 107 CFU/mL. The combination of 0.4× MIC from AgNPs and phage with Multiplicity of Infection (MOI) 0.1 showed an inhibitory effect. This combination of AgNPs and phage offers a prospect of nanoparticles with significantly enhanced antibacterial properties and therapeutic performance.


Nanomaterials ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2475
Author(s):  
Amirah Shafilla Mohamad Kasim ◽  
Arbakariya Bin Ariff ◽  
Rosfarizan Mohamad ◽  
Fadzlie Wong Faizal Wong

Silver nanoparticles (AgNPs) have been found to have extensive biomedical and biological applications. They can be synthesised using chemical and biological methods, and coated by polymer to enhance their stability. Hence, the changes in the physico-chemical characteristics of AgNPs must be scrutinised due to their importance for biological activity. The UV-Visible absorption spectra of polyethylene glycol (PEG) -coated AgNPs displayed a distinctive narrow peak compared to uncoated AgNPs. In addition, High-Resolution Transmission Electron Microscopy analysis revealed that the shapes of all AgNPs, were predominantly spherical, triangular, and rod-shaped. Fourier-Transform Infrared Spectroscopy analysis further confirmed the role of PEG molecules in the reduction and stabilisation of the AgNPs. Moreover, dynamic light scattering analysis also revealed that the polydispersity index values of PEG-coated AgNPs were lower than the uncoated AgNPs, implying a more uniform size distribution. Furthermore, the uncoated and PEG-coated biologically synthesised AgNPs demonstrated antagonisms activities towards tested pathogenic bacteria, whereas no antagonism activity was detected for the chemically synthesised AgNPs. Overall, generalisation on the interrelations of synthesis methods, PEG coating, characteristics, and antimicrobial activity of AgNPs were established in this study.


Polymers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1586
Author(s):  
Michelina Catauro ◽  
Pavel Šiler ◽  
Jiří Másilko ◽  
Roberta Risoluti ◽  
Stefano Vecchio Ciprioti

The present study investigated the structure, morphology, thermal behavior, and bacterial growth analysis of novel three-component hybrid materials synthesized by the sol-gel method. The inorganic silica matrix was weakly bonded to the network of two organic components: a well-known polymer such as polyethylene glycol (PEG, average molar mass of about 4000 g/mol), and an antioxidant constituted by chlorogenic acid (CGA). In particular, a first series was made by a 50 wt% PEG-based (CGA-free) silica hybrid along with two 50 wt% PEG-based hybrids containing 10 and 20 wt% of CGA (denoted as SP50, SP50C10 and SP50C20, respectively). A second series contained a fixed amount of CGA (20 wt%) in silica-based hybrids: one was the PEG-free material (SC20) and the other two contained 12 and 50 wt% of PEG, respectively (SP12C20 and SP50C20, respectively), being the latter already included in the first series. The X-ray diffraction (XRD) patterns and scanning electron microscope (SEM) images of freshly prepared materials confirmed that all the materials were amorphous and homogeneous regardless of the content of PEG or CGA. The thermogravimetric (TG) analysis revealed a higher water content was adsorbed into the two component hybrids (SP50 and SC20) because of the availability of a larger number of H-bonds to be formed with water with respect to those of silica/PEG/CGA (SPC), where silica matrix was involved in these bonds with both organic components. Conversely, the PEG-rich materials (SP50C10 and SP50C20, both with 50 wt% of the polymer) retained a lower content of water. Decomposition of PEG and CGA occurred in almost the same temperature interval regardless of the content of each organic component. The antibacterial properties of the SiO2/PEG/CGA hybrid materials were studied in pellets using either Escherichia coli and Enterococcus faecalis, respectively. Excellent antibacterial activity was found against both bacteria regardless of the amount of polymer in the hybrids.


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