scholarly journals PENGARUH EKSTRAK ASHITABA TERHADAP KADAR SERUM GLUTAMIC OXALOACETIC TRANSAMINASE DAN SERUM GLUTAMIC PYRUVIC TRANSAMINASE PADA TIKUS DENGAN LUKA BAKAR

2021 ◽  
Vol 5 (2) ◽  
pp. 85-95
Author(s):  
Andrew - Johan ◽  
Regina Oktavia ◽  
Lusiana Batubara ◽  
Dwi Ngestiningsih ◽  
Innawati Jusup
Keyword(s):  
Burn Injury ◽  
Wilcoxon Test ◽  
Control Group ◽  
Glutamic Pyruvic Transaminase ◽  
Glutamic Oxaloacetic Transaminase ◽  
Serum Glutamic Pyruvic Transaminase ◽  
Control Group Design ◽  
Serum Glutamic Oxaloacetic Transaminase ◽  
Treatment Groups ◽  
Significant Difference

Background: Serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) are increased in tissue damage. Ashitaba contains many compounds that can reduce serum SGOT and SGPT levels. Objective: This study was proposed to prove that giving Ashitaba extract could reduce serum SGOT and SGPT levels in rats exposed to burn injury. Methods: This study used a posttest only control group design with 20 rats as samples. All research samples were treated with second-degree burns and were divided into 2 different groups, the treatment group (given Ashitaba extract 300 mg /kg BW) and the control group. The blood serum was analyzed for SGOT and SGPT test on the 2nd, 8th, and 14th days. For statistical analysis, the Wilcoxon test used to analyze the levels of serum SGOT and SGPT. Results: There was no significant difference in serum SGOT and SGPT levels between the control and treatment groups on the 2nd, 8th, and 14th days Conclusion: Ashitaba extract could not reduce serum SGOT and SGPT levels in rats exposed to burn injury.

scholarly journals Efek Hepatoprotektor Ekstrak Terpurifikasi Batang Galing (Cayratia trifolia L.Domin) Pada Tikus Putih Wistar Jantan (Rattus noervegicus)

2018 ◽  
Vol 4 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Muhammad Ilyas Yusuf ◽  
Selfyana Austin Tee ◽  
Karmila Karmila ◽  
Asriullah Jabbar
Keyword(s):  
Control Group ◽  
Glutamic Pyruvic Transaminase ◽  
Glutamic Oxaloacetic Transaminase ◽  
Serum Glutamic Pyruvic Transaminase ◽  
Control Group Design ◽  
Serum Glutamic Oxaloacetic Transaminase ◽  
Group Design ◽  
Post Test ◽  
Cayratia Trifolia ◽  
Test Control

Hepatoprotektor adalah suatu senyawa yang dapat memberikan perlindungan pada hati dari kerusakan hati. Salah satu cara untuk mengetahui fungsi hati dengan mengukur aktivitas enzim Serum Glutamic Oxaloacetic Transaminase (SGOT) dan Serum Glutamic Pyruvic Transaminase (SGPT). Salah satu bahan alam yang berpotensi memiliki efek hepatoprotektor adalah tumbuhan Galing dan telah dilakukan penelitian bahwa tumbuhan galing mengandung senyawa flavonoid yang berpotensi sebagai antioksidan. Tujuan penelitian untuk mengetahui efek hepatoprotektor dari ekstrak terpurifikasi batang galing dosis 400 mg/ kgBB pada tikus wistar jantan setelah diinduksi Paracetamol dosis toksik. Jenis penelitian adalah eksperimental laboratorium, dengan desain pre  and  post  test  control  group  design  dan menggunakan 12 ekor tikus putih yang dibagi dalam  3 kelompok perlakuan dengan empat kali pengulangan yang diinduksi dengan paracetamol dosis toksik setelah pemberian ekstrak. Berdasarkan hasil penelitian menunjukkan bahwa pemberian ekstrak terpurifikasi batang galing dengan dosis 400 mg/kgBB, memberikan efek hepatoprotektor yang efektif terhadap peningkatan kadar SGPT setelah diinduksi paracetamol dosis toksik

DIFFERENCES IN THE NUMBER OF CANDIDA ALBICANS COLONIES ON ACRYLIC RESIN AND THERMOPLASTIC NYLON IN SOURSOP LEAF EXTRACT IMMERSION

2021 ◽  
Vol 17 (2) ◽  
pp. 123-131
Author(s):  
Ria Koesomawati ◽  
Keyword(s):  
Candida Albicans ◽  
Leaf Extract ◽  
Acrylic Resin ◽  
Wilcoxon Test ◽  
Control Group ◽  
Control Group Design ◽  
Test Analysis ◽  
Denture Stomatitis ◽  
Treatment Groups ◽  
Significant Difference

Introduction: Denture stomatitis is a chronic inflammation caused by wearing dentures, mainly caused by Candida albicans. Heat-polymerized acrylic resins are often used as denture bases, but lack the ability to absorb liquids due to their porosity and surface roughness. The basis of the latest dentures is thermoplastic nylon because it is more aesthetically, hypoallergenic and more flexible. Soursop leaf extract contains alkaloids, tannins, flavonoids, and saponins as antifungal. The purpose of this study was to examinate whether there were differences in the number of Candida albicans colonies on heat-polymerized acrylic resin plates and thermoplastic nylon in soursop leaf extract immersion. Materials and Methods: The research design was an experimental pre-post test with control group design, n = 50 plates were divided into 2 groups, heat-polymerized acrylic resin (n=25) and thermoplastic nylon (n=25), divided into 5 groups, 3 treatment groups using 10%,15%,25% soursop leaf extract, Fittident®and aquadest in the control groups. Samples were contaminated with Candida albicans suspension and incubated, counted before immersion for 8 hours, then put in Saboroud’s bath and counted again. Results and Discussions: Wilcoxon test analysis showed significant differences in all groups, except the aquadest group. The Mann-Whitney test showed significant differences between the treatment groups, except between the 25% extract and the Fittident®control group. Also, showed a significant difference in the 15% concentration group between heat-polymerized acrylic resin and thermoplastic nylon. Conclusion:There was a difference in the decrease in the number of Candida albicans colonies on heat-polymerized acrylic resin plates and thermoplastic nylon in soursop leaf extract at a concentration of 15%, while at concentrations of 10% and 25% there was no difference

Effectiveness Of Toilet Training Education On Mother's Behavior And Toddler Age Toilet Training Ability (18-36 Months)

2020 ◽  
Vol 5 (2) ◽  
pp. 49-55
Author(s):  
Hafiko Andresni ◽  
Zahtamal Zahtamal ◽  
Winda Septiani ◽  
Mitra Mitra ◽  
Lita Lita
Keyword(s):  
Sampling Technique ◽  
T Test ◽  
The Body ◽  
Toilet Training ◽  
Wilcoxon Test ◽  
Control Group ◽  
Maternal Knowledge ◽  
Control Group Design ◽  
Significant Difference

ABSTRACT Toilet training is an effort to train children to be able to control and urinate (BAK) and defecate (BAB). Toilet training is one of the main tasks of children at toddler age. Toilet training is one of the main tasks of children in toddler age which is very important to be done to create independence in children in controlling BAK and BAB and children know the parts of the body and their functions. Data in 2012 shows that ± 60% of parents do not teach toilet training to children from an early age. The aim of the study was to find out the effectiveness of toilet training education on maternal behavior and toilet skills in toddler age training (18-36 months). The study was conducted in July-August 2018. This type of quantitative research used the design of the Quasy pretest and posttest experiment with non-equivalent control group design. Samples were 36 mothers and 36 children with purposive sampling technique. Data analysis used Paired t test, Wilcoxon test, Man-Whitney test an Independent t test. The results showed that toilet training education through lecture methods, modules and maze games was more effective than toilet training education through lecture and leaflet methods on children's knowledge and abilities. Conversely, for the role of mothers in supervision there is no significant difference in effectiveness. Health education is recommended in health promotion programs to increase maternal knowledge, the role of mothers and the ability of toilet training children independently. Keywords: Toilet training, Lecture method, Module, Maze game, Leaflet, Knowledge, Role of mother, Children's ability.

Particular Matter of Motor Vehicle Exposure and High-Fat Diet Effects on Kidney Histopathology, Creatinine, and Malondialdehyde (MDA) Levels in Wistar Rats

2021 ◽  
Vol 5 (3) ◽  
pp. 124-128
Author(s):  
Rizka Veni ◽  
Awal Prasetyo ◽  
Muflihatul Muniroh
Keyword(s):  
High Fat Diet ◽  
Wistar Rats ◽  
Motor Vehicle ◽  
Histopathological Change ◽  
Normal Diet ◽  
Control Group ◽  
High Fat ◽  
Control Group Design ◽  
Treatment Groups ◽  
Significant Difference

This study aims to analyze the effect of combination of motor vehicle particular matter exposure and high-fat diet in kidney histopathology, creatinine levels, and MDA levels in Wistar rats. This study used a posttest-only control group design. Eighteen healthy male Wistar rats were divided into three groups. The intervention groups received motor vehicle fume exposure for 100 s with normal diet (X1) or high-fat diet (X2), and the control group received no exposure (C). Data analysis was processed with a SPSS 25.0 computer program by using the one-way ANOVA test followed by post hoc LSD. The degree of kidney histopathological damage showed significant differences between the X1 and X2 groups when compared with the control group (p < 0.05). The results of the creatinine level examination found a significant difference between the X2 and C groups (p < 0.05) and the treatment groups X1 and X2 (p < 0.05). The results of kidney MDA level examination showed a significant difference between the treatment groups (X1 and X2) and the control group (p < 0.05). The combination of particular matter of motor vehicle fumes exposure and high-fat diet could induce kidney damage through histopathological change and increased creatinine levels and kidney MDA levels in Wistar rats.

The effect of patience training on university students’ patience and life satisfaction levels

2021 ◽  
Vol 9 (3) ◽  
pp. 712-719
Author(s):  
Ayşe Eliüşük Bülbül ◽  
Keyword(s):  
Life Satisfaction ◽  
University Students ◽  
Wilcoxon Test ◽  
Control Group ◽  
Control Group Design ◽  
Satisfaction Scale ◽  
Significant Difference ◽  
Post Test ◽  
And Control ◽  
Experimental Group

The purpose of this study is to determine the effect of the "patience training program" on the patience and life satisfaction levels of university students. The study was organized as a pre-test, post-test experiment and control group design. For a total of 30 students from which were 17 in the control group and 17 in the experimental group, patience training was given for 5 weeks. The "Patient Scale" developed by Schnitker (2010) and adapted to Turkish by Eliüşük and Arslan (2016) and the "Life Satisfaction Scale" developed by Diener, Emmons, Larsen and Griffin (1985) and adapted to Turkish by Dağlı and Baysal (2016) were used as a data collection tool in the study. The "Wilcoxon" test was used for the comparison of in-group differences in the analysis of obtained data and the "Mann-Whitney U" test was used in examining the differences between the two groups. As a result of the study, it was observed that the patience and life satisfaction average scores of students in the experimental group receiving "patience training" increased significantly, while there was no significant difference in the patience and life satisfaction averages scores of the control group students.

scholarly journals penyuluhan menggunakan media lembar balik terhadap pengetahuan dan sikap ibu balita mengenai Kadarzi

2019 ◽  
Vol 11 (1) ◽  
pp. 58
Author(s):  
Ulfah Sofindra Syahidatunnisa ◽  
Holil M Par'i ◽  
Fred Agung Suprihartono ◽  
Fred Agung Suprihartono ◽  
Rr. Nur Fauziyah ◽  
...  
Keyword(s):  
Total Sample ◽  
Wilcoxon Test ◽  
Control Group ◽  
Control Group Design ◽  
Knowledge And Attitudes ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Knowledge And Attitude ◽  
Attitudinal Changes ◽  
Experimental Group

One of the factors that influence Kadarzi's achievement is the knowledge and attitudes of the toddler's mother. This study aims to determine the effect of counseling using backsheet media on the knowledge and attitudes of toddlers' mothers about Kadarzi in the Cipeundeuy Health Center District of West Bandung Regency. The research design used was quasi-experimental with a pre-post test control group design model with a total sample of 28 people each for the experimental group and the control group. The experimental group was given an intervention in the form of counseling using flipchart media, while the control group was given an intervention in the form of counseling using leaflet media. The results obtained from the Wilcoxon test in the experimental group and the t-dependent test in the control group were changes in the increase in knowledge and attitude scores in the experimental group and the control group after intervention (p <0.005). The results of the Mann-Whitney test showed no significant difference between knowledge and attitude scores in the experimental group and the control group (p> 0.005). It is better to do further research related to Kadarzi's behavior so that the application of the Kadarzi indicator can be monitored so that it can describe the results of attitudinal changes, and to increase Kadarzi's knowledge and attitudes to toddler mothers.

scholarly journals Pengaruh Terapi AIUEO terhadap Kemampuan Bicara Pasien Stroke yang Mengalami Afasia Motorik

2019 ◽  
Vol 1 (2) ◽  
pp. 226-235
Author(s):  
Afnijar Wahyu ◽  
Liza Wati ◽  
Murad Fajri
Keyword(s):  
Wilcoxon Test ◽  
Control Group ◽  
Stroke Patients ◽  
Control Groups ◽  
Control Group Design ◽  
Treatment Groups ◽  
Group Design ◽  
Motor Aphasia ◽  
A Value ◽  
And Control

The purpose of this study was to determine the effect of AIUEO therapy on the speech ability of stroke patients who have motor aphasia in Raja Ahmad Thabib Hospital Tanjungpinang. The research design used was quasi experiment with the Nonequivalent Control Group Design approach to 9 respondents who were divided into 9 treatment groups and 9 control groups. The results showed that there were significant differences in the functional ability of communication between the control and treatment groups with a value of p <0.05 (p = 0.007 at a = 0.05) using the Wilcoxon Test statistical test. Conclusion, the influence of AIUEO therapy on the speech ability of stroke patients with motor aphasia in the treatment and control groups at Ahmad Thabib Hospital Tanjungpinang.   Keywords: Speech Ability, Motor Aphasia Stroke, AIUEO Therapy

scholarly journals PENGARUH AKTIFITAS FISIK CONTINUOUS RUNNING DAN INTERVAL RUNNING TERHADAP SERUM GLUTAMIC OXALOACETIC TRANSAMINASE (SGOT) DAN SERUM GLUTAMIC PYRUVIC TRANSAMINASE (SGPT)

2019 ◽  
Vol 3 (1) ◽  
pp. 12
Author(s):  
Novita Sari Harahap ◽  
Riski Pranata
Keyword(s):  
Glutamic Pyruvic Transaminase ◽  
Glutamic Oxaloacetic Transaminase ◽  
Serum Glutamic Pyruvic Transaminase ◽  
Serum Glutamic Oxaloacetic Transaminase ◽  
Group Design ◽  
Continuous Running

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh aktifitas fisik continuous running dan interval running terhadap SGOT dan SGPT pada mahasiswa Ikor Unimed Tahun 2017. Penelitian dilakukan di Stadion Universitas Negeri Medan, Laboratorium Fisik FIK, dan Laboratorium Kesehatan Daerah Dinas Kesehatan Provinsi Sumatera Utara. Metode penelitian yang digunakan dalam penelitian ini adalah metode eksperimen. Sampel penelitian menggunakan mahasiswa Ikor Unimed  sebanyak 14 orang. Desain penelitian menggunakan Pretest-Posttest Group Design. Aktifitas fisik continuous Running dan interval running dilakukan dengan menggunakan Treadmill selama 12 menit dengan intensitas 60-70 %. Pemeriksaan kadar SGOT dan SGPT dilakukan di awal dan di akhir perlakuan. Teknik analisis data pada penelitian ini menggunakan uji t.  Hasil penelitian menunjukkan  bahwa peningkatan rerata kadar SGOT setelah aktifitas fisik continuous running sebesar 88,00 U/L yang sebelumnya sebesar 60,89 U/L dan setelah aktifitas fisik interval running sebesar 81,61 U/L yang sebelumnya 60,41 U/L. Hasil uji analisis diperoleh nilai p=0,662, yang menunnjukkan bahwa ada peningkatan namun tidak terdapat perbedaan yang bermakna p>0,05. Begitu juga dengan rerata kadar SGPT setelah aktifitas fisik continuous running sebesar 82,21 U/L yang sebelumnya sebesar 57,16 U/L dan setelah aktifitas fisik interval running sebesar 81,80 U/L yang sebelumnya 59,59 U/L. Hasil uji analisis diperoleh nilai p=0,655, yang menunnjukkan bahwa ada peningkatan namun tidak terdapat perbedaan yang bermakna p>0,05. Penelitian ini menyimpulkan bahwa bahwa tidak terdapat perbedaan yang bermakna antara aktifitas fisik continuous running dan aktifitas fisik interval running terhadap peningkatan SGOT dan SGPT pada mahasiswa IKOR UNIMED tahun 2017.Kata kunci: Continuous Running, Interval Running, SGOT dan SGPT

scholarly journals Anti-Inflammatory Effect of Musa acuminata Stem

2020 ◽  
Vol 14 (02) ◽  
pp. 294-298
Author(s):  
Maharani Laillyza Apriasari ◽  
Selviana Rizky Pramitha ◽  
Dewi Puspitasari ◽  
Diah Savitri Ernawati
Keyword(s):  
Treatment Group ◽  
Musa Acuminata ◽  
Control Group ◽  
Control Group Design ◽  
Treatment Groups ◽  
Tnf Α ◽  
Significant Difference ◽  
Anti Inflammatory ◽  
Mucosal Wound ◽  
Inflammatory Effect

Abstract Objective This study was designed to assess the anti-inflammatory effect of Musa acuminata through the expression of tumor necrosis factor-α (TNF-α) and nuclear factor kappa β (NF-κB) after 3 days of application of Musa acuminata stem extract (MASE) gel on oral mucosal wound. Materials and Methods An experimental study with post-test only control group design was conducted. Twenty male Rattus norvegicus (Wistar) were injured on their left buccal mucosa and treated three times a day with MASE gel of varying concentrations: 0% (as control), MASE 25%, MASE 37.5%, and MASE 50%. On day 3, a biopsy was performed on each mucosal wound for later immunohistochemical analysis for the expressions of TNF-α and NF-κB. Results The highest expression of TNF-α was observed in the control group (13.20 ± 1.79), while the lowest was in the treatment group using 50% MASE (6.40 ± 1.14). Meanwhile the comparison between treatment groups did not highlight any significant difference (p > 0.05). The highest expression of NF-κB was observed in the control group (13.20 ± 1.30), whereas the lowest was in the treatment group using MASE 50% (6.40 ± 1.14). NF-κB was significantly lower in the treatment group using MASE 50% when compared with other treatment groups (p < 0.05). Conclusion Application of MASE on mucosal wound reduces the expression of TNF-α and NF-κB at all concentrations. The anti-inflammatory effect of MASE 50% was the strongest one.

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