Experience of using the drug «Selenopiran» to optimize indicators of reproduction of dairy cows

2020 ◽  
Vol 1 (8) ◽  
pp. 33-37
Author(s):  
M. S. Lodyanoy ◽  
◽  
A. I. Erzutov ◽  
Keyword(s):  
Postpartum Period ◽  
Hematological Parameters ◽  
Live Weight ◽  
Reproductive Organs ◽  
Control Group ◽  
Blood Indices ◽  
Service Period ◽  
Daily Milk Yield ◽  
And Control ◽  
Experimental Group

As a result of research and production experience in the economy of the Nizhny Novgorod region, the effect of three-time administration of the drug «Selenopiran» at a dose of 300 mg during the dry season on the ease of calving, milk productivity and reproductive functions of cows was studied. For this purpose, two groups of cows (n=10) were selected: an experimental group and a control group. Starting from the confirmation of 6-month pregnancy, 25% oil solution of the drug «Selenopiran» at a dose of 30 ml was administered three times at intervals of 5–6 days to animals of the experimental group. 14 days after last injection from experimental and control animals were taken blood samples for haematological study determined the red blood indices: the number of red blood cells and hemoglobin, white blood: white blood cell count and leukocyte formula, and lysozime and bactericidal activity of blood serum. Further, the animals were monitored both during calving and postpartum period, and during subsequent artificial insemination and lactation, the duration of independent and manual separation of the afterbirth, the frequency of occurrence, form, duration of the course and outcome of specific diseases of the postpartum period (endometritis and early mastitis) were recorded. Fruitful insemination was determined based on the results of rectal studies. Based on these observations, the main indicators of herd reproduction were calculated, i.e. the insemination index (the number of inseminations per 36 fruitful), the duration of the period and the interbody period. As a result, the service period in the experimental group decreased by 113,7% relative to the control animals (178,2 days versus 2,3), the insemination index also improved in the experimental group – 3,8, against 1,6 in the control group. The average daily milk yield in the experimental group is 2,9 kg higher, and the live weight of calves at birth is XNUMX kg. A comparative analysis of hematological parameters of experimental and control cows obtained a higher level of markers of nonspecific immunity in the experimental group. Consequently, along with relatively rapid recovery of reproductive organs and shortening of the service period, the cows of the experimental group also had higher indicators of non-specific resistance compared to the cows of the control group.

EFFICIENCY NON-TRADITIONAL FEED IN CATTLE BREEDING IN YAKUTIA

2020 ◽  
Author(s):  
Н.М. ЧЕРНОГРАДСКАЯ ◽  
М.Ф. ГРИГОРЬЕВ ◽  
А.И. ГРИГОРЬЕВА ◽  
А.Н. КЮНДЯЙЦЕВА
Keyword(s):  
Milk Production ◽  
Live Weight ◽  
Feed Additives ◽  
Control Group ◽  
Milk Productivity ◽  
The Difference ◽  
The Republic ◽  
Daily Milk Yield ◽  
And Control ◽  
Experimental Group

Целью исследований являлось определение эффективности производства молока при внедрении местных нетрадиционных кормовых добавок в кормлении первотелок красной степной породы. Научно-производственных опыт был проведен в условиях сельхозкооператива Республики Саха (Якутия). По методу аналогов были сформированы опытная и контрольная группы. В период проведения производственного опыта первотелки контрольной группы потребляли основной рацион. Первотелки опытной группы дополнительно к основному рациону получали на 1 голову цеолит в дозе 1 г на 1 кг живой массы, 300 г сапропеля и 60 г Кемпендяйской соли. При включении местных нетрадиционных кормовых добавок в рацион первотелок отмечено улучшение молочной продуктивности. В опытной группе на производство 1 кг молока было затрачено 1,48 ЭКЕ против 1,67 в контрольной группе. При сравнении среднесуточного удоя отмечена разница в контрольной группе 7,73 кг, в опытной — 8,58 кг молока, при этом валовое производство молока составило 127185 и 141215 кг, соответственно. Включение местных нетрадиционных кормовых добавок в состав рациона первотелок способствовало повышению молочной продуктивности на 10,09%. При изучении экономической эффективности внедрения местных нетрадиционных кормовых добавок в кормлении первотелок было установлено, что в опытной группе животных было дополнительно получено 653,5 тыс. руб. при дополнительных затратах 19,8 тыс. руб. Таким образом, использование местных нетрадиционных кормовых добавок в кормлении первотелок способствует повышению молочной продуктивности. The aim of the research was to determine the efficiency of milk production when introducing local non-traditional feed additives in the feeding of heifers of the red steppe breed. Scientific experience was carried out in the conditions of the Agricultural Production Cooperative "Crosses" of the Suntarsky district of the Republic of Sakha (Yakutia). To conduct the experiment, the experimental and control groups were formed by the method of analogues. During the production experience, the control group first calves consumed the main diet. An experimental group of heifers in addition to the main diet received zeolite per 1 head in a dose of 1 g per 1 kg of live weight, 300 g of sapropel and 60 g of Kempendiai salt. When local non-traditional feed additives were included in the feeding of heifers, there was an improvement in milk productivity, so in the experimental group of animals 1.48 energy feed units were spent on the production of 1 kg of milk compared to 1.67 in the control group. When comparing the average daily milk yield, the difference in the control group was 7.73 kg, and in the experimental group 8.58 kg of milk, while the gross milk production was 127185 and 141215 kg, respectively. The inclusion of local non-traditional feed additives in the diet of heifers contributed to an increase in milk productivity by 10.09%. When studying the economic efficiency of introducing local non-traditional feed additives in the feeding of heifers, it was found that 653.5 thousand rubles were received in the experimental group of animals. at additional costs 19.8 thousand rubles. Thus, the use of local non-traditional feed additives in feeding heifers contributes to an increase in milk productivity.

scholarly journals Impact complexes nanokarboksylativ and drug Kvatronan-Se on hematological parameters of blood of experimental animals

2017 ◽  
Vol 19 (74) ◽  
pp. 123-126
Author(s):  
N. B. Seba ◽  
M. A. Khomenko
Keyword(s):  
Blood Cells ◽  
Hematological Parameters ◽  
Live Weight ◽  
Control Group ◽  
Experimental Animals ◽  
Group I ◽  
Control Research ◽  
Research Experiment ◽  
The Village ◽  
Experimental Group

In this paper present the results of research of influence of the preparation «Kvatronan-Se» and carboxylates of Se, Cu, Mn, Cr, Ge in different combinations on haematological parameters of blood of experimental animals. Study was carried out on the basis of PC Haleks-Agro. It is located in the village Gul'sk of Novograd Volynskiy district of Zhytomyr region. In the farm to bred of Simmental cows. For the experiment was formed four groups. We took into account age, live weight of 650–700 kg and the average milk yield 5000–6000 kg. Animals is located in identical conditions of feeding and maintenance. Research experiment was carried out on animals couples counterparts.  Preparations introduced animals three times at 10–12 days after insemination. The cows first experimental group were injected complex nanokarboksylativ Ge, Cu, Mn and Cr, second – drug Kvatronan–Se and animals third experimental group was administered a complex composed of Se, Cu, Mn, Cr. On 13 day after insemination in experimental animals were taken blood from tail vein and examined the contents of hematological parameters. Established that injection nanokarboksylativ enhance the fertility of cows in the first and third group, the figure rose to 20% in the second by 40% compared with the control. Research hematological parameters blood  animals shows that after entering content drugs of blood cells had minor changes but remained within the physiological norm. The results show that in  concentration monocyte the second group  was at 5.53% (P > 0.01) higher compared to the control group and 2.3% compared to the first and third. The content of lymphocytes in this group decreased by 26.3% (P > 0.05), 22% and 16% relative to the control, the first and third groups. Also, it should be noted that the hemoglobin in the experimental groups decreased in group I by 7.9% in the II – 3.9% and III by 7.3% compared with the control group. Also, these groups distinguished downward trend eosinophils 1.8%, 1.5%, 2.05%. Then, as the number of segment-nuclear neutrophils contrast, in the first group increased by 18.2% in the second and third at 16.9% comparatively control. The number of monocytes in the second group doslfidniy the suspicion was higher by 66.3% and 0.3% higher than the physiological norm – it may indicate a high immune response.

MONIZEN FORTE FOR LAMBS PARASIT-IC DISEASES

2020 ◽  
Vol 2 ◽  
pp. 84-87
Author(s):  
E. S. Engasheva ◽  
◽  
V. I. Kolesnikov ◽  
Keyword(s):  
Clinical Signs ◽  
Live Weight ◽  
Control Group ◽  
Not Given ◽  
The North ◽  
Condi Tions ◽  
High Infection ◽  
Mucous Discharge ◽  
And Control ◽  
Experimental Group

The Monizen Forte test for parasitic sheep diseases was tested under production condi-tions on 460 lambs of the North Caucasian breed, with a live weight of 25-30 kg, with high infection with nematodes, cestodes and larvae of the nasopharyngeal gadfly (Oestrus ovis), which were given orally in a mixture with half the normal rate of concentrated feed, the test drug in a dose of 1 ml per 20 kg of the animal weight. Experienced (20 ani-mals) and control (10 animals) groups of lambs with an average live weight of 28 kg were selected from these lambs according to the principle of analogues. To the lambs of the control group, the drug was not given. 10 days after administration of the drug by clini-cal and coprological studies, it was found that the lambs of the experimental group, the intensity of nematode invasion decreased and the drug’s intensity (IE) was 96.7%, and the extensivity (EE) was 95%. The lambs of the experimental group before the introduction of the drug were 40% invaded with moniesia and 50% dictiocauli, and after using Monizen Forte they were released - the ex-tensibility (EE) was 100%. Lambs of the control (untreated) group, the intensity and extent of infection with nematodes and ces-todes remained at the same level as at the beginning of the experiment. All 10 lambs (50%) of the experimental group, the clinical signs of estrosis (sneezing, snorting, serous-mucous discharge from the nose) disap- peared, and the lambs of the control group have these clinical signs persisted.

scholarly journals The Effect of a Probiotic Preparation on Growth and some Biochemical and Physiological Indicators of Quail

2020 ◽  
pp. 61-65
Author(s):  
И.Ю. Постраш ◽  
И.В. Сучкова ◽  
Е.Г. Скворцова ◽  
О.В. Филинская ◽  
А.В. Мостофина
Keyword(s):  
Comparative Analysis ◽  
Live Weight ◽  
Favorable Effect ◽  
Control Group ◽  
Average Weight ◽  
Control Groups ◽  
Significant Difference ◽  
Probiotic Preparation ◽  
And Control ◽  
Experimental Group

Изучение влияния пробиотического препарата ЭМ-курунга на приросты, анализы крови и помёта птиц проведено на примере цыплят техасских белых перепелов. В качестве объекта исследований использовались цыплята перепелов, начиная с суточного возраста. Средняя масса цыплят на начало эксперимента составила 9,2±0,12 г. Цыплят забивали в возрасте 90 суток. Установлено, что введение в рацион цыплят пробиотического препарата ЭМ-курунга в количестве 0,2 мл на 1 кг живого веса увеличивает сохранность молодняка на 14,8% и приросты птенцов – на 10%. Сравнительный анализ биохимических данных опытной и контрольной групп птицы показал, что введение в рацион опытной группы пробиотика практически не повлияло на белковый обмен. Общий белок у опытной птицы был недостоверно меньше, по сравнению с контролем, на 1,25%, та же картина наблюдалась по уровню альбуминов – меньше на 1,9%, глобулинов – на 1%. Сравнительный анализ показателя кислотности кала птиц опытной и контрольной групп показал достоверное различие. Так, у контрольной группы рН кала имел среднее значение 6,5, у перепелов опытной группы – 7,5. Таким образом, у опытной птицы, в сравнении с контрольной, активная кислотность кишечного содержимого достоверно сдвинулась в слабощелочную сторону, что свидетельствует о благоприятном воздействии пробиотика на микрофлору желудочно-кишечного тракта перепелов, снижая уровень патогенной микрофлоры, активно развивающейся в кислой среде. The study of the effect of the probiotic preparation EM-Kurunga on gains, blood tests and poultry litter was carried out using the example of White Texas quail chickens. Quail chickens starting at daily age were used as the subject of research. The average weight of chickens at the beginning of the experiment was 9.2±0.12 g. Chickens were slaughtered at the age of 90 days. It was established that the introduction of the probiotic preparation EM-Kurunga into the diet of chickens in the amount of 0.2 ml per 1 kg of live weight increases the safety of young animals by 14.8% and the gains of poults – by 10%. A comparative analysis of the biochemical data of the experimental and control groups of poultry showed that the introduction of the probiotic into the diet of the experimental group had practically no effect on protein metabolism. The total protein in the experimental poultry was insignificantly less than in the control by 1.25%, the same pattern was observed in the level of albumin – less by 1.9%, globulins – by 1%. Comparative analysis of the acidity index of poultry feces from the experimental and control groups showed a significant difference. So, in the control group the pH of feces had an average value of 6.5, in the quails of the experimental group – 7.5. Thus, in the experimental poultry in comparison with the control one the active acidity of the intestinal contents significantly shifted to the slightly alkaline side, which indicates a favorable effect of the probiotic on the microbiota of the quail gastrointestinal tract, reducing the level of pathogenic microflora actively developing in an acidic condition.

Cost-effectiveness implementation of the new protocol for prevention of after calving complications in first-calf heifers

2020 ◽  
pp. 91-98
Author(s):  
E. Frolova ◽  
A. Abilov ◽  
S. Erin
Keyword(s):  
Economic Efficiency ◽  
Control Group ◽  
Reproduction Rate ◽  
New Drug ◽  
Service Period ◽  
Gynecological Diseases ◽  
Reproduction Process ◽  
And Control ◽  
Experimental Group

The article is devoted to determination of the new drug Aldiecoseptimol (Patent 2562929) effectiveness for the prevention of the after calving complications of gynecological diseases in first-calf heifers, with the calculation of the values of the service period, its impact on the level of reproduction and economic efficiency in comparison with the control. The work was carried out in highly productive herds of the Moscow region with a daily productivity of 35-40 liters of milk, with completed lactation (305) days of 7200-8000 kg of milk. The effectiveness of prevention was evaluated based on the results of the actual service period in the experimental (n=113) and control (n=102) groups as follows: the service period is less than 85 days — the surplus group, SP-85 days-optimal, SP-86-120 days-deficient, SP-121-135 days or more-acutely deficient in the level of reproduction and output of calves. It was found that after preventive treatments, the number of the first-calf heifers with insemination efficiency of up to 85 days increases and makes up 40% of their total number in the experiment compared to 22% in the control (18% in favor of experience). There was a significant reduction in animals with a service period of more than 121 days: from 60% in the control to 30% in the experiment (acutely deficient group). In the experimental group, compared with the control group, the indicator of the level of reproduction and output of calves increased. The obtained data were processed in accordance with a mathematical model developed by us to optimize the planning of the reproduction process and evaluate the economic efficiency of using a new drug. It was found that the new Protocol for processing first-calf heifers in the of after calving period for the prevention of gynecological diseases contributed to an increase in the number of animals in surplus, in terms of reproduction and output of calves, from 22% in the control to 40% in the experiment. The number of animals with an acute service period decreased from 60% in the control group to 30% in the experimental group. The calculated yield of calves in the experimental group increased on average from 79.4% in the control to 95.4% in the experiment per 100 cows, which was 20.2%. The reproduction rate also increased by 20.2% and amounted to 46 heifers per 100 head of cows in the experimental group instead of 38 heifers per 100 head of cows in the control group. Protocol using the new drug Eldecanato proposed for prevention of after calving complications and gynecological diseases in cows, reduced service period and days's barrenness at 77.6 days, and contributed to the increase of output of calves per 100 cows by 20.2%. All this were permitted to increase economic efficiency in the experimental group by 17.7 thousand rubles per 1 cow per year

scholarly journals The influence of the silage with high acidity on the rumen fermentation of cows

2004 ◽  
Vol 52 (1) ◽  
pp. 91-96
Author(s):  
Petr Doležal
Keyword(s):  
Acid Content ◽  
Rumen Fluid ◽  
Live Weight ◽  
Rumen Fermentation ◽  
Mean Value ◽  
Control Group ◽  
Maize Silage ◽  
Group A ◽  
And Control ◽  
Experimental Group

Twenty dairy cows were used in an experiment at which the influence of silages with different content of acids on the rumen fermentation was studied. Animals were divided into experimental and control group, each of them about 10 individuals. Feeding ratio consisted of maize silage (26 kg), alfalfa silage (13 kg), meadow hay (1 kg) and corn mixture (8.5 kg). The experimental group was fed an inoculated maize silage, with higher contents of fermentation acids. Intake of total acids per 1 kg live weigh was higher in the experimental group than control group (1.98 g/kg; 1.48 g/kg live weight, respectively). The rumen fluid was taken per orally 2-3 hours after feeding. Mean value of pH of rumen fluid was significantly (P<0.05) lower in the experimental group (5.8 ± 0.08) in comparison with control group (6.2 ± 0.06).The most significant increase (P<0.01) of VFA content (125 ± 5.2 mmol/l) and lactic acid content (4.8 ± 0.2 mmol/l) was observed in rumen fluid of experimental group. Significant differences (P<0.05) of propionic acid and butyric acid content were also found out between the groups. Nevertheless, acetic acid content was insignificant (P>0.05) lower in experimental group. A protozoa (infusoria) content was significantly (P<0.01) lower in the experimental group (175.76 ± 12.54 thousand/ml) as compared with the control group (288.1 ± 13.73 thousand/ml).

scholarly journals Influence of parenteral application of beta-carotene on fertility in cows

2008 ◽  
Vol 62 (1-2) ◽  
pp. 53-66
Author(s):  
Miljan Velickovic ◽  
Dragan Vukovic
Keyword(s):  
Beta Carotene ◽  
Physiological Solution ◽  
Control Group ◽  
Reproductive Disorders ◽  
Significant Discrepancy ◽  
Holstein Breed ◽  
Physiological Limits ◽  
Service Period ◽  
And Control ◽  
Experimental Group

Thirty Holstein breed cows from the breeding stock of high yielding dairy cattle were selected for testing. The cows were selected during their high gravidity and fell into two groups. The i.m beta-carotene, Carofertin, of 20 ml (200 mg of beta-carotene) was applied to the experimental group (n=15) two weeks before the expected parturition date. Another injection of the beta-carotene preparation was applied to the experimental group two weeks after parturition. Simultaneously, a physiological solution of 20 ml was injected i.m to the experimental group (n=15). The blood samples for testing of the beta-carotene and vitamin A concentration were taken during high gravidity and in the early puerperium two days after the beta-carotene application and on the day of parturition. Two-of parenteral application of beta-carotene before parturition does not have an impact significantly on the frequency of the occurrence of retained placenta in experimental cows comparing to the cows of the control group (x=33.3 % and x=20.0 %) and length of the service period (x =97.20?31.64 and x=98.8?35.8 days). Based on the results obtained during this research, it can be concluded that the parenteral application of the beta-carotene (Carofertin) as 200 mg per cow, which is meant for protection of the reproductive disorders of cows, does not affect the level of carotinemia when its concentration in the blood serum is within the physiological limits. Therefore, no significant discrepancy in values of the reproduction figures between the cows of the experimental and control group was found. All in all, its usage is advisable only during scarce feeding.

scholarly journals EVALUATION OF EFFICIENCY OF APPLICATION OF FEED ADDITIVE ON BROILER CHICKENS

2020 ◽  
Vol 21 (2) ◽  
pp. 90-95
Author(s):  
T. R. Levytskyі
Keyword(s):  
Broiler Chickens ◽  
Hematological Parameters ◽  
Average Daily Gain ◽  
Live Weight ◽  
Feed Additives ◽  
Poultry Meat ◽  
Feed Additive ◽  
Control Group ◽  
Feed Conversion ◽  
Experimental Group

A study of the effectiveness of the use of feed additive Liaform in relation to its effect on the growth and development of broiler chickens. For research, 2 groups of broiler chickens of 55 heads (control and experimental) from 8 days of age were formed on the principle of analogues. Feeding of the control group was carried out with standard complete feed. Feeding of the experimental group was carried out with standard complete feed, in which the feed additive Liaform was added at the rate of 2 g / kg. During the experiment, the general condition of the bird, the safety of the bird, zootechnical and hematological parameters were monitored. It is established that the studied feed additive has a positive effect on the productivity of broiler chickens, improves feed absorption. As a result of the use of feed additive Liaform live weight of broiler chickens in the experimental group was 4.3 % higher compared to the control. The average daily gain of chickens in the experimental group exceeded this figure of chickens in the control group by 4,1 %. The use of feed additives helped to increase feed conversion. The use of Liaform feed increased the protein level in poultry meat

The correlation of productive and hematological parameters in steers on the background of the use of feed protein additive Biovitel

2020 ◽  
pp. 27-34
Author(s):  
A. Pauli ◽  
E. Vetrovaya ◽  
R. Fatkullin
Keyword(s):  
Hematological Parameters ◽  
Physiological State ◽  
Correlation Coefficients ◽  
Live Weight ◽  
The Body ◽  
Feed Additive ◽  
Control Group ◽  
Feed Protein ◽  
Chelyabinsk Region ◽  
Experimental Group

Among the environmental factors, feeding is the most important in the formation of new traits and properties. The level of feeding influences first of all on the digestive system. Then the nature of feeding affects the organs associated with the utilization of nutrients, and ultimately the body as a whole. The purpose of the researches was to study the correlation between productive and hematological parameters in steers against the background of the use of the feed additive Biovitel. The research has been carried out under the environments of JSC “SHF Dubrovsky” in the Chelyabinsk region on steers of Hereford breed. In order to carry out experiments 2 groups of steers (control and experimental) have been formed with 10 heads in each. The method of pair-analogues has been used taking into account the genotype, age, birth weight and physiological state of animals. The experiment has been conducted from 6- to 15-month-old steers. The control group has been received the main farm ration. The experimental group has been received the basic ration and additional feed additive Biovitel at the rate of 100 g/head/ day for 15 days. The correlation between hematological parameters and productivity of steers against the background of the use of the feed additive Biovitel has been determined. During the study a positive correlation between the total protein and protein fractions with the live weight of steers has been observed. High correlation coefficients have been obtained in steers of both groups at the age of 9 months. The amount of total lipids in all age periods in both groups changed relatively little, but the trend of their increase in steers of the experimental group remained. The concentration of phospholipids in the control group was almost at the same level, and in the experimental group there was an excess of control values by 5,52 %. Activation of redox processes in the animal body has been observed under the action of the feed protein additive Biovitel.

scholarly journals IMMUNO-BIOCHEMICAL STATUS OF SWEETS AT CORRECTION OF REPRODUCTION VIOLATIONS WITH THE APPLICATION OF «E-SELENA» AND «OVARIOVITA» IN THE CONDITIONS OF THE INDUSTRIAL COMPLEX

2018 ◽  
pp. 146-152
Author(s):  
N. V. Shulgin ◽  
V. I. Pleshakova ◽  
V. S. Vlasenko ◽  
A. A. Zhernosenko ◽  
O. I. Nakonechny
Keyword(s):  
Average Daily Gain ◽  
Live Weight ◽  
Absolute Lymphocyte Count ◽  
Lymphoid Cells ◽  
Control Group ◽  
Industrial Complex ◽  
Simultaneous Application ◽  
Blood Indices ◽  
Significant Difference ◽  
Experimental Group

The aim of the authors was to determine the effect of the selenium-containing preparation «E-selenium» and the homeopathic preparation «Ovariovit» on the reproductive indices of sows, as well as the tasks: to study the morpho-biochemical and immunological status of clinically healthy animals; evaluate the performance of the sows under investigation. The experiment on the basis of a large industrial pig complex in the Omsk region using healthy sows selected according to the principle of analogues allowed us to establish that the simultaneous application of the studied complex of drugs allows achieving high productive results. The positive effect of the preparations is indicated by the production parameters of the experimental group with a significant difference from the control group, consisting in a shortening of the farrowing period (P <0.01); an insignificant increase in the number of live-born piglets, the weight of the nest at birth, the average daily gain, and the average live weight of the piglets during weaning. The introduced complex «E-selenium» and «Ovariovit» with the purpose of correction of reproductive functions of sows positively influences blood indices, so on the 30th day after administration of drugs the amount of creatinine in the sows of the experimental group significantly decreased to 320.18 ± 8.69 against 401, 5 ± 13.43 in the control group (P≤0.001); a significant increase in the content of total protein in the blood of the test animals was observed by 9 % (P≤0.05). Immunological studies have confirmed the beneficial effect of selenium-containing and homeopathic preparations, namely on the 30th day after the introduction of the complex it was found that in the sows of the experimental group there was an increase in the number of leukocytes by 50 % and erythrocytes by 25.4 % (P <0.05) with values in the control group of animals. There was also a significant increase in absolute lymphocyte count in the peripheral blood. At the same time, an increase in the number of lymphoid cells was due to all populations. Especially it is necessary to allocate cytotoxic T-lymphocytes, the concentration of which relative to control increased by 2.6 times (P <0.05).

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