Norovirus: A Growing Cause of Gastroenteritis in Catalonia (Spain)?

2013 ◽  
Vol 76 (10) ◽  
pp. 1810-1816 ◽  
Author(s):  
A. MARTÍNEZ ◽  
N. TORNER ◽  
S. BRONER ◽  
R. BARTOLOMÉ ◽  
S. GUIX ◽  
...  
Keyword(s):  
Incidence Rates ◽  
Chi Square ◽  
Term Care ◽  
Major Health Problem ◽  
Common Cause ◽  
Salmonella Infections ◽  
Chi Square Test ◽  
Common Etiology ◽  
Foodborne Outbreaks ◽  
Private Homes

Infectious acute gastroenteritis (AGE) is a major health problem worldwide. Salmonella is a leading cause of AGE outbreaks, but viruses may be responsible for up to 80% of cases. We compared the frequency and characteristics of AGE outbreaks in Catalonia due to norovirus and Salmonella and the changes in these outbreaks from 2000 through 2010. In 2006 through 2010, we also investigated the distribution by season, setting, and implicated food, the incidence rates of cases associated, and the hospitalization rates. Differences in proportions were estimated by Pearson's chi-square test, and the odds ratio (OR) and 95% confidence interval (CI) were calculated. In 2000 through 2010, the number of AGE outbreaks caused by Salmonella decreased and those caused by norovirus significantly increased. From 2006 onward, norovirus was the most common etiology in AGE outbreaks, but in foodborne outbreaks, Salmonella was the more common cause until 2010. The incidence rate per 105 inhabitants was greater for norovirus (20.81 versus 3.97, P < 0.001), and the hospitalization rate was lower for norovirus (0.84 versus 4.69, P < 0.001). Salmonella infections occurred more frequently in the warmer months, and norovirus infections were more common in the colder months, both in terms of total outbreaks (OR = 4.50; 95% CI, 2.85 to 7.11; P < 0.001) and foodborne outbreaks (OR = 4.38; 95% CI, 2.42 to 7.95; P < 0.001). Norovirus infections were less common in private homes (OR = 0.08; 95% CI, 0.04 to 0.14; P < 0.001) and more common in nursing homes (P < 0.001) and hospitals or long-term care facilities (OR = 14.09; 95% CI, 3.35 to 59.33; P < 0.001). Foods most frequently implicated in norovirus infection outbreaks were seafood (22%; OR = 7.89; 95% CI, 2.59 to 24.3; P < 0.001), and those most common in Salmonella infection outbreaks were mayonnaise and similar items (30.2%; OR = 0.05; 95% CI, 0.01 to 0.22; P < 0.001). Foodborne outbreaks in which the vehicle was not identified were more frequent in cases of norovirus infection (OR = 4.59; 95% CI, 2.54 to 8.30; P < 0.001). Our results indicate that norovirus rather than Salmonella is the most common cause of AGE outbreaks in Catalonia. Foodborne AGE outbreaks were more commonly caused by norovirus than by Salmonella only in 2010, the last year of the study.

scholarly journals Association of cervical carcinogenesis risk with HPV16 E6 and E7 variants in the Taizhou area, China

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mei-Zhen Dai ◽  
Yi Qiu ◽  
Xing-Hong Di ◽  
Wei-Wu Shi ◽  
Hui-Hui Xu
Keyword(s):  
Cervical Cancer ◽  
Cervical Carcinogenesis ◽  
Chi Square ◽  
Major Health Problem ◽  
Hpv16 E6 ◽  
Exact Test ◽  
Chi Square Test ◽  
E6 And E7

Abstract Background Human papillomavirus (HPV) type 16 accounts for a larger share of cervical cancer and has been a major health problem worldwide for decades. The progression of initial infection to cervical cancer has been linked to viral sequence properties; however, the role of HPV16 variants in the risk of cervical carcinogenesis, especially with longitudinal follow-up, is not fully understood in China. Methods We aimed to investigate the genetic variability of HPV16 E6 and E7 oncogenes in isolates from cervical exfoliated cells. Between December 2012 and December 2014, a total of 310 single HPV16-positive samples were selected from women living in the Taizhou area, China. Sequences of all E6 and E7 oncogenes were analysed by PCR-sequencing assay. Detailed sequence comparison, genetic heterogeneity analyses and maximum-likelihood phylogenetic tree construction were performed with BioEdit Sequence Alignment Editor and MEGA X software. Data for cytology tests and histological diagnoses were obtained from our Taizhou Area Study with longitudinal follow-up for at least 5 years. The relationship between HPV16 variants and cervical carcinogenesis risk was analysed by the chi-square test or Fisher’s exact test. Results In this study, we obtained 64 distinct variation patterns with the accession GenBank numbers MT681266-MT681329. Phylogenetic analysis revealed that 98.3% of HPV16 variants belong to lineage A, in which the A4 (Asian) sublineage was dominant (64.8%), followed by A2 (12.1%), A1 (11.4%), and A3 (10.0%). The A4 (Asian) sublineage had a higher risk of CIN2+ than the A1–3 (European) sublineages (OR = 2.69, 95% CI = 1.04–6.97, P < 0.05). Furthermore, nucleotide variation in HPV16 E6 T178G is associated with the development of cervical cancer. Conclusion These data could provide novel insights into the role of HPV16 variants in cervical carcinogenesis risk in China.

scholarly journals SPECTRUM OF OPTIC NEUROPATHIES PRESENTING IN NEUROOPHTHALMOLOGY CLINIC AT AFIO

2021 ◽  
Vol 71 (1) ◽  
pp. 112-16
Author(s):  
Umer Ijaz ◽  
Asad Habib ◽  
Hassan Sajjad Rathore ◽  
Muhammad Imran Sarwar
Keyword(s):  
Optic Neuropathy ◽  
Armed Forces ◽  
Descriptive Study ◽  
Ischemic Optic Neuropathy ◽  
Hospital Record ◽  
Chi Square ◽  
Common Cause ◽  
Common Presentation ◽  
Chi Square Test ◽  
Common Association

Objective: To study the spectrum of optic neuropathies in patient’s presenting at AFIO Rawalpindi. Study Design: Descriptive study/retrospective study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Jan 2017 to Dec 2017. Methodology: Retrospective analysis of hospital record of patients coming to neuro-ophthalmic clinic of ArmedForces Institute of Ophthalmology (AFIO), Rawalpindi, from Jan to Dec 2017 was done. Only patients with clearfinal diagnosis of neurophthalmic disease were included. Those with vague diagnosis were excluded. Data wasentered in SPSS version 22 and grouped into variables before analysis. Chi-square test was used for statisticalanalysis. The p<0.05 was considered significant. Results: Forty-five patients were included in study including 33 (73.3%) males and 12 (26.6%) females. Mean age of patients was 41.64 ± 17.74 years. Patients were grouped into ischemic optic neuropathy 20%, toxic optic neuropathies 20%, compressive optic neuropathies 17.7%, inflammatory optic neuropathies 11%, neuroretinitis 6.7%, hereditary optic neuropathies 6.7%, multiple sclerosis (MS) related 4.4%, neuromylitis optics spectrum (NMO-SD) related 4.4%, traumatic optic neuropathies 4.4% and nutritional optic neuropathies 4.4%. Deficiency of vitamin B12 and vitamin D was strongly associated with nutritional optic neuropathies while raised TLC was most common association with inflammatory optic neuropathies (57.14%) and of neuroretinitis (66%). Anti-tuberculosis drugs were most common cause of toxic optic neuropathies (88.88%). Chi square test was used for statistical analysis and p<0.05 was considered significant. Conclusion: Ischemic optic neuropathy is the most common presentation in our population according to ourstudy. However...........

scholarly journals Hubungan antara Jenis Kelamin dan Kejadian Kematian Mendadak di RSUP Prof. Dr. R. D Kandou Manado

e-CliniC ◽  
2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Gerrit J. Pangemanan ◽  
Djemi Tomuka ◽  
Nola T.S. Mallo
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Sudden Death ◽  
Analytical Study ◽  
Sampling Method ◽  
P Value ◽  
Chi Square ◽  
Common Cause ◽  
Chi Square Test ◽  
The Relationship

Abstract: Sudden death could occur in anyone regardless of gender either male or female. This study was aimed to determine the relationship between gender and the incidence of sudden death at Prof. Dr. R. D. Kandou Hospital Manado. This was a descriptive analytical study with across sectional design using total sampling method. The results showed 345 cases of sudden deaths consisted of 209 males and 136 females. The age ranges were 0-1 years (7 cases), 1-18 years (7 cases), 18-40 years (38 cases), 40-60 years (138 cases), and >60 years (155 cases). Coronary heart disease was the leading cause of sudden deaths (40 cases). Data analyzed by using Chi-square test showed a P value of 0.838. Conclusion: There was no relationship between gender and the incidence of sudden death. Sudden deaths were most common among males, age >60 years, with coronary heart disease as the most common cause of sudden death.Keywords: gender, sudden death Abstrak: Kematian mendadak dapat terjadi pada siapa saja, tidak memandang jenis kelamin baik laki-laki maupun perempuan. Penelitian ini bertujuan untuk mengetahui hubungan antara jenis kelamin dan kejadian kematian mendadak di RSUP Prof. Dr. R. D Kandou Manado. Jenis penelitian ialah deskriptif analitik dengan desain potong lintang menggunakan metode total sampling. Hasil penelitian mendapatkan 345 kasus kematian mendadak terdiri dari 209 laki-laki dan 136 perempuan. Rentang usia 0-1 tahun berjumlah 7 kasus, usia 1-18 tahun berjumlah 7 kasus, usia 18-40 tahun berjumlah 38 kasus, usia 40-60 tahun berjumlah 138 kasus, dan usia >60 tahun berjumlah 155 kasus. Penyakit jantung koroner merupakan penyebab kematian mendadak terbanyak dengan jumlah 40 kasus. Analisis data menggunakan uji chi-kuadrat mendapatkan P=0,838. Simpulan: Tidak terdapat hubungan antara jenis kelamin dengan kejadian kematian mendadak. Sebagian besar kematian mendadak ditemukan pada laki-laki, kelompok usia >60 tahun, dengan penyebab penyakit jantung koroner.Kata kunci: jenis kelamin, kematian mendadak

scholarly journals Hubungan Diare dengan Status Gizi Balita di Kelurahan Lubuk Buaya Kecamatan Koto Tangah Kota Padang

2013 ◽  
Vol 2 (3) ◽  
pp. 11
Author(s):  
Alania Rosari ◽  
Eka Agustia Rini ◽  
Masrul Masrul
Keyword(s):  
Infectious Disease ◽  
Nutritional Status ◽  
Random Sampling ◽  
Univariate Analysis ◽  
Bivariate Analysis ◽  
Chi Square ◽  
Cross Sectional ◽  
Major Health Problem ◽  
Chi Square Test ◽  
Nutritional Status Of Children

AbstrakMalnutrisi pada anak masih menjadi masalah kesehatan utama di dunia. Data dari WHO pada tahun 2010 menunjukkan sebanyak 18% anak usia di bawah lima tahun di negara berkembang mengalami underweight. Keadaan kurang gizi dapat meningkatkan risiko terkena penyakit infeksi karena daya tahan tubuh yang menurun. Sebaliknya, penyakit infeksi juga dapat memengaruhi status gizi karena asupan makanan menurun, malabsorpsi, dan katabolisme tubuh meningkat. Penelitian ini bertujuan untuk menentukan apakah terdapat hubungan antara diare dengan status gizi balita. Jenis penelitian ini adalah studi observasional dengan desain cross sectional. Populasi penelitian adalah ibu dan balita usia 12-60 bulan yang bertempat tinggal di Kelurahan Lubuk Buaya. Sampel yang diambil sebanyak 145 orang dengan metode proportionate random sampling. Data dikumpulkan dengan kuesioner untuk mengetahui riwayat diare dalam sebulan terakhir dan penimbangan berat badan. Data diolah dengan uji statistik chi square menggunakan program SPSS 17.0. Hasil analisis univariat menunjukkan terdapat balita berstatus gizi baik (84,1%), status gizi kurang (13,8%), dan status gizi buruk (2,1%). Terdapat 25,5% balita yang pernah mengalami diare dengan rerata durasi diare 3,0 hari. Hasil analisis bivariat menunjukkan tidak terdapat hubungan bermakna antara diare dengan status gizi (BB/U) balita di Kelurahan Lubuk Buaya (p=0,742). Penelitian ini memperlihatkan bahwa tidak terdapat hubungan antara diare dengan status gizi balita di Kelurahan Lubuk Buaya Kecamatan Koto Tangah Kota Padang.Kata kunci: status gizi balita, diareAbstractMalnutrition in children is still a major health problem in the world. Data from WHO in 2010 showed 18% of children under five years old in developing countries are underweight. Malnutrition may increase the risk of infectious disease because the immune system is decreased. Otherwise, infectious disease can also affect the nutritional status because of decreased food intake, malabsorption, and increased body catabolism. This study aimed to determine association between diarrhea and nutritional status of children. The study was an observational study with cross sectional design. The population is mother and children aged 12- 60 months residing in Lubuk Buaya Village. There are 145 samples taken with proportionate random sampling method. Data were collected with questionnaire to determine the history of diarrhea in the last month and weighing. The data were processed with chi square test by using SPSS 17.0 program. Results of univariate analysis showed that there are children with good nutritional status (84,1%), underweight (13,8%), and poor nutritional status (2,1%). There are 25,5% children had diarrhea with average duration of illness 3,0 days. Results of bivariate analysis showed no significant association between diarrhea and nutritional status (weight/age) of children in Lubuk Buaya Village (p = 0,742). This study showed no association between diarrhea and nutritional status of children in Lubuk Buaya Village, Koto Tangah Subdistrict, Padang City.Keywords: nutritional status of children, diarrhea

Trends in the incidence of work-related traumatic limb amputations in South Korea from 2004 to 2013

2019 ◽  
Vol 43 (4) ◽  
pp. 409-417 ◽  
Author(s):  
Inpyo Jeon ◽  
Ja-Ho Leigh ◽  
Jun-Soo Ro ◽  
Young Sun Ro ◽  
Seung Hak Lee ◽  
...  
Keyword(s):  
South Korea ◽  
Incidence Rate ◽  
Epidemiological Data ◽  
Incidence Rates ◽  
Chi Square ◽  
Establishment Size ◽  
Work Related ◽  
Incidence Trends ◽  
Chi Square Test ◽  
Compensation Claims

Background:Epidemiological data for work-related traumatic limb amputations are limited worldwide, particularly incidence trends related to workplace characteristics.Objectives:To investigate nationwide incidence rates and trends for amputations according to industry and establishment size.Study design:Retrospective cohort study.Methods:Incidence rates were calculated using workers’ compensation claims in South Korea from 2004 to 2013. Age–sex standardization was conducted, and trends related to workplace characteristics were statistically analyzed using the chi-square test.Results:The overall incidence rate was 38.8 claims per 100,000 workers. Decreasing trends over time in age–sex standardized incidence were observed. Most claims occurred in manufacturing and construction industries. Incidence within the manufacturing decreased significantly ( p < 0.001), but not in the construction ( p = 0.130) industry. Small-sized establishments (<50 employees) accounted for 77.8% of claims. Incidence in small establishments significantly decreased between 2004 and 2013 ( p < 0.001).Conclusion:A decreasing incidence rate for traumatic amputations in manufacturing and small establishments may imply that preventive measures have been successful in South Korea. If so, these strategies may be useful for other fast-growing Asian economies. Further research is needed to identify the causes of traumatic amputations according to industry and establishment size.Clinical relevanceTrends in the incidence rate of work-related traumatic limb amputations related to workplace characteristics can provide useful information for policy makers to improve prevention strategies.

scholarly journals Risk of surgical site infection in patients undergoing orthopedic surgery

2011 ◽  
Vol 19 (6) ◽  
pp. 1362-1368 ◽  
Author(s):  
Flávia Falci Ercole ◽  
Lúcia Maciel Castro Franco ◽  
Tamara Gonçalves Rezende Macieira ◽  
Luísa Cristina Crespo Wenceslau ◽  
Helena Isabel Nascimento de Resende ◽  
...  
Keyword(s):  
Risk Factors ◽  
Surgical Site Infection ◽  
Descriptive Analysis ◽  
Surgical Site Infections ◽  
Incidence Rates ◽  
Site Infection ◽  
Chi Square ◽  
Historical Cohort ◽  
Surgical Site Infection Incidence ◽  
Chi Square Test

This study aimed to identify risk factors associated with surgical site infections in orthopedic surgical patients at a public hospital in Minas Gerais, Brazil, between 2005 and 2007. A historical cohort of 3,543 patients submitted to orthopedic surgical procedures. A descriptive analysis was conducted and surgical site infection incidence rates were estimated. To verify the association between infection and risk factors, the Chi-square Test was used. The strength of association of the event with the independent variables was estimated using Relative Risk, with a 95% confidence interval and p<0.05. The incidence of surgical site infection was 1.8%. Potential surgical wound contamination, clinical conditions, time and type of surgical procedure were statistically associated with infection. Identifying the association between surgical site infection and these risk factors is important and contributes to nurses’ clinical practice.

scholarly journals factors related to the event of gastritis disease in kelurahan tanjung pinang, jambi city in 2018

2019 ◽  
Vol 4 (1) ◽  
pp. 99
Author(s):  
Melda Yenni ◽  
Sugiarto Sugiarto ◽  
Rumiati Rumiati
Keyword(s):  
Coffee Consumption ◽  
Sampling Technique ◽  
Total Sample ◽  
World Health ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Major Health Problem ◽  
The World ◽  
Chi Square Test

Non-communicable diseases are a major health problem in developing countries that are experiencing a demographic transition and a decline in lifestyle in their communities. The WHO 2013 World Health Research Agency, conducted a review of several countries in the world, obtained a percentage of gastritis in the world, including Britain 22%, China 31%, Japan 14.5%, Canada 35%, and France 29.5%. Based on data from the Jambi City Health Office from 20 puskesmas the number of gastritis cases was 83.21% and the highest number of gastritis events was at tanjung pinang health center, which was 5.91%. This study was conducted to determine the factors associated with the incidence of gastritis in Tanjung Pinang Village, Jambi City. The research design used was quantitative with a cross sectional approach. The population in this study was the productive age community in the area of Tanjung Pinang which numbered 9,489 people. The sampling technique uses Random Sampling techniques with a total sample of 95 respondents. This research was conducted on September 28, October 16, 2018. Data obtained were analyzed by univariate and bivariate using the Chi-Square test. The results showed that there was a relationship between eating patterns with the incidence of gastritis p-value 0,000 (P-Value <0.05), coffee consumption with the incidence of gastritis p-value 0.027 (P-Value <0.05) and the relationship of stress levels with Gastritis incidence p-value 0,000 (P-Value <0.05). It is expected that respondents and the community will always maintain a regular diet, reduce or limit coffee consumption in a day, and exercise for one hour and relax regularly, recreation/refreshing, share or manage work time properly

scholarly journals Association of thrombocytopenia with splenomegaly in malaria patients in East Kalimantan: A cross-sectional, retrospective study

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1832
Author(s):  
Loly R.D. Siagian ◽  
Vera M. Lumbantoruan ◽  
Nurul Hasanah ◽  
Fransiska A. Sihotang ◽  
Carta Gunawan
Keyword(s):  
Retrospective Study ◽  
Laboratory Data ◽  
Public Hospitals ◽  
Common Finding ◽  
Severe Thrombocytopenia ◽  
Chi Square ◽  
Cross Sectional ◽  
Major Health Problem ◽  
East Kalimantan ◽  
Chi Square Test

Background: Malaria still presents as a major health problem in Indonesia and specifically in East Kalimantan. One common finding in malaria is thrombocytopenia, the mechanism of which is still unclear. Several studies have suggested some mechanisms, one of which is splenomegaly. This study aimed to discover the association between thrombocytopenia and splenomegaly of malaria patients in East Kalimantan. Methods: This study was a descriptive retrospective study with clinical and laboratory data obtained from the medical records of malaria patients in four major public hospitals from January 2015 to July 2018. The association between thrombocytopenia with splenomegaly was analysed using Chi-Square test. Results: A total of 215 patients were included; 189 male (87.9%) and 26 female (12.1%). The most common aetiology were Plasmodium vivax (43.2%), P. falciparum (42.8%), and mixed infection (P. falciparum and P. vivax) (4.6%). The distribution of thrombocyte count were normal in 28 patients (13%) and decreased in 187 patients (87%). Among patients with thrombocytopenia, the percentage of mild, moderate and severe thrombocytopenia was 18.2%, 43.8% and 33%, respectively. Splenomegaly was found in only 11 patients (5.1%). We found no association between thrombocytopenia with splenomegaly (p=0.61). Conclusions: We conclude that thrombocytopenia is not associated with splenomegaly in these malaria patients.

scholarly journals Pengaruh pemberian Air Susu Ibu eksklusif terhadap kejadian Infeksi Saluran Pernapasan Atas pada balita di wilayahkerja Puskesmas Kopelma Darussalam

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Novita Andayani ◽  
Iflan Nauval ◽  
Trinita Sukma Zega
Keyword(s):  
Community Health ◽  
Health Center ◽  
Exclusive Breastfeeding ◽  
Respiratory Infections ◽  
Community Health Center ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Major Health Problem ◽  
Chi Square Test

Abstrak. Infeksi Saluran Pernapasan Atas (ISPA) merupakan penyakit infeksi yang masih menjadi masalah kesehatan utama di Indonesia yang dapat disebabkan oleh berbagai macam virus yang menginfeksi tubuh balita dengan kekebalan tubuh yang masih lemah. Salah satu faktor yang dapat menyebabkan ISPA pada balita ialah pemberian ASI ekslusif. ASI ekslusif memiliki kandungan gizi dan sistem kekebalan yang melindungi balita dari infeksi. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian ASI eksklusif terhadap kejadian ISPA pada balita di Wilayah Kerja Puskesmas Kopelma Darussalam.  Variabel dalam penelitian ini diukur dengan menggunakan kuisioner pemberian ASI ekslusif pada balita. Metode penelitian ini adalah analitik observasional dengan rancangan cross sectional. Jumlah sampel sebanyak 63 balita diambil dengan teknik Non Random (Non Probability) Sampling dengan metode Accidental sampling. Analisis statistik yang digunakan adalah uji Chi-Square. Data penelitian menunjukkan balita yang diberikan ASI ekslusif sebesar 30,2% dan balita yang mengalami kejadian ISPA sebesar 82,5%. Hasil penelitian ini didapatkan bahwa p-value =0,008 yang menunjukkan adanya pengaruh pemberian ASI eksklusif terhadap kejadian ISPA pada balita di Wilayah Kerja Puskesmas Kopelma Darussalam. Balita yang tidak mendapatkan ASI ekslusif lebih banyak mengalami kejadian ISPA.Kata kunci: Air Susu Ibu (ASI) esklusif, ISPA, balitaAbsrtact. Acute Respiratory Infections (ARI) is an infectious disease that still a major health problem in Indonesia which can be caused by various viruses that infect the bodies of infants with weak immune bodies. One factor that can cause ARI in infants is exclusive breastfeeding. Exclusive breastfeeding has nutritional and immune systems that protect infants from infection. This research aims to determine the effect of exclusive breastfeeding on the incidence of ARI in infants in the Community Health Center Kopelma Darussalam. These variables measured by exclusive breastfeeding questionnaire in infants respectively . The type of the research is analytical observational study with cross sectional  design. The samples is 63 infants who are taken by Accidental sampling. The statistical analysis of the research were analyzed using Chi-Square test. The result of the research showed that 30.2% infants who were given exclusive breastfeeding and 82,5% infants who experienced ARI events. The conclusion of this study shows p-value=0,008 that the influence of exclusive breastfeeding on the incidence of ARI in infants in the Community Health Center Kopelma Darussalam . The Infants who do not get exclusive ASI experience more ARI events. Key words: exclusive breastfeeding, ARI, infants

scholarly journals Incidence, Age-Specific, and Regional Distribution of Myocardial Infarction in Zanjan Province, Iran, during 2014-2019

2021 ◽  
Keyword(s):  
Myocardial Infarction ◽  
Incidence Rate ◽  
Regional Distribution ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Incidence Rates ◽  
Current Status ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

Background: Myocardial Infarction (MI) is one of the most important cardiovascular diseases and the leading cause of 39% of deaths in Iran. Due to the different geographical diversity in Zanjan province, Iran, this study aimed to investigate the incidence, age-specific, and regional distribution of myocardial infarction in Zanjan province, Iran. Methods: This cross-sectional study was conducted at Zanjan University of Medical Sciences (ZUMS), Zanjan, Iran, in 2020. Data were collected from nine hospital information systems. The incidence rate, age-specific, and regional distribution of MI were calculated for each county. Chi-square test, independent sample t-test, and binary logistic regression methods were used to investigate significant relationships between variables. All statistical analyses were performed using RStudio and R software. Results: In total, 3,723 MI patients were hospitalized in ZUMS hospitals during 2014-2019. The overall incidence rate of MI was 348 cases (95% CI, 337-359) per 100,000 population. Moreover, the prevalence of this condition was higher in males compared to females and at age 80 and over. The incidence rates of MI increased by 84% from 49 cases (95% CI: 47-55) in 2014 to 90 cases (95% CI: 88-99) in 2019 (P<0001). Moreover, the highest incidence rate of MI was observed in Khorramdareh and Ijrood counties. Conclusion: This study provided an overview of the current status of MI incidence in Zanjan province, Iran. The highest incidence of MI was observed in males and at the southeast of the studied area. This study can help health authorities and policymakers prioritize resource allocation and employ prevention programs to reduce the incidence rate of MI.

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