P-080: The clinical significance of the study of the hemostatic system in the planning of pregnancies in women taking hormonal contraceptives for a long time

2017 ◽  
Vol 151 ◽  
pp. S134
Author(s):  
N. Khamani ◽  
V. Bitsadze ◽  
D. Kapanadze
Keyword(s):  
Clinical Significance ◽  
Hormonal Contraceptives ◽  
Hemostatic System ◽  
Long Time

scholarly journals No Evidence That Hormonal Contraceptives Affect Chemosensory Perception

i-Perception ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 204166952098333
Author(s):  
Martin Schaefer ◽  
Behzad Iravani ◽  
Artin Arshamian ◽  
Johan N. Lundström
Keyword(s):  
Potential Effect ◽  
Bayes Factors ◽  
Taste Perception ◽  
Hormonal Contraceptives ◽  
Trigeminal System ◽  
Odor Perception ◽  
Chemosensory Perception ◽  
Long Time ◽  
Taste Detection ◽  
Taste Thresholds

The use of oral contraceptives (OC) in the form of a hormonal pill has been widespread for decades. Despite its popularity and long-time use, there is still much ambiguity and anecdotal reports about a range of potential side effects. Here, we addressed the potential effect of OC use on chemosensory perception. Previous research has almost exclusively focused on olfaction, but we expanded this to the trigeminal system and the sense of taste. We used Bayesian statistics to compare the olfactory, trigeminal, and taste detection abilities between a group of 34 normal cycling women and a group of 26 women using OC. Our results indicated that odor, trigeminal, and taste thresholds were not affected by the use of OC. Moreover, neither odor perception, nor taste perception was affected; all with Bayes factors consistently favoring the null hypothesis. The only exception to these results was odor identification where Bayes factors indicated inconclusive evidence. We conclude that effects of OC use on chemosensory perception are unlikely, and if present, likely are of no to little behavioral relevance.

Identifizierung von Risikogenen für den Herzinfarkt durch genomweite Assoziationsstudien

2010 ◽  
Vol 30 (04) ◽  
pp. 230-235 ◽  
Author(s):  
P. Linsel-Nitschke ◽  
J. Erdmann ◽  
H. Schunkert
Keyword(s):  
Genetic Variants ◽  
Scientific Discovery ◽  
Association Studies ◽  
Genome Wide Association Studies ◽  
Dna Array ◽  
Genomweite Assoziationsstudien ◽  
Hemostatic System ◽  
Genome Wide ◽  
Array Technology ◽  
Long Time

SummaryMyocardial infarction (MI) shows a strong heritability. For a long time the identification of responsible genes has been rather unsuccessful. However, with the advent of genome wide association studies (GWAS) using DNA-array technology a number of significant loci for MI have been identified which were widely replicated. Interestingly, only a small fraction of the hitherto identified genes is also associated with classical risk factors for MI such as hypercholesterolemia or diabetes. Therefore it can be concluded that the MI risk mediated by the newly identified genes involves a number of novel pathophysiological mechanisms.This review summarizes the present state of knowledge in the field and tries to give a perspective on how these findings can be translated into clinical practice and further scientific discovery. Special consideration is given to the association of MI risk with genetic variants in the hemostatic system.

PENGARUH LAMA PEMAKAIAN ALAT KONTRASEPSI SUNTIK DMPA TERHADAP DISFUNGSI SEKSUAL DI WILAYAH KERJA PUSKESMAS KAMANDRE

2018 ◽  
Vol 8 (01) ◽  
pp. 703-709
Author(s):  
Ny Patmahwati
Keyword(s):  
Sexual Dysfunction ◽  
Health Center ◽  
Time Use ◽  
Sampling Technique ◽  
Hormonal Contraceptives ◽  
P Value ◽  
Cross Sectional ◽  
Injectable Contraceptive ◽  
Long Time ◽  
Over Time

Injectable contraceptive Depot Medroxy progesterone Acetate (DMPA) is one of the hormonal contraceptives that is widespread and increases over time. According to WHO, today almost 380 million couples run family planning and 66 - 75 million of them, especially in developing countries, using hormonal contraceptives. The use of contraceptive DMPA injections for a long time will cause sexual dysfunction in the form of decreased libido. This research is a research to find out the influence of long time use of DMPA injection tool to decrease libido in working area of Kamandre Health Center. The data collection time approach in this study is cross sectional. Population in this research is all mother of KB acceptor, who visited at Kamandre Health Center of Luwu Regency at. The sample in this research is all of the DM acceptors of DMPA acceptor who visited at Kamandre Public Health Center during October - November 2017 with Sampling technique of Pourposive Sampling. The result of the study showed 38 respondents old use Kb injection <24 months 11% which decreased libido and 39% did not decrease libido. While the duration of use Kb injection> 24 months 47% decreased libido and 3% did not decrease libido, so that the result of computerized statistic test obtained p value is 0.000 (p <0,005) means Ho rejected and Ha received. From the results of the study can be concluded that there is Influence between the long use of DMPA Injecting with Sexual Dysfunction in the Working Area of Kamandre Puskesmas Luwu District. Keywords : Duration of DMPA Injection Usage, Decreased Libido

scholarly journals Disturbances in the hemostatic system of patients with endogenous hypercorticism and metabolic syndrome

2010 ◽  
Vol 56 (4) ◽  
pp. 34-38 ◽  
Author(s):  
Iu V Khodakova ◽  
S D Arapova ◽  
G A Sukhanova ◽  
L D Chirkova ◽  
L Ia Rozhinskaia
Keyword(s):  
Metabolic Syndrome ◽  
High Risk ◽  
General Population ◽  
Metabolic Regulation ◽  
Active Phase ◽  
Vascular Wall ◽  
Thromboembolic Complications ◽  
Hemostatic System ◽  
Long Time

Long-standing hypercortisolemia is accompanied by multiple defects of metabolic regulation. Glucocorticoids are known to affect not only metabolic processes but also the vascular wall directly influencing its remodeling and angiogenesis. Syndrome of endogenous hypercorticism is characterized by various disturbances in the hemostatic system and a tendency toward the development of hypercoagulation. Altered metabolic and hemostatic parameters in the active phase of the disease persist during a long time after the achievement of remission. It accounts for the high risk of atherosclerosis, atherothrombosis, and thromboembolic complications which necessitates correction with medicinal preparations throughout the follow-up period. According to foreign authors, thromboembolic complications are the main cause of mortality among the patients with this clinical condition and occur 4 times as frequently as in the general population.

200kv superconducting cryo electron microscope

1987 ◽  
Vol 45 ◽  
pp. 642-643
Author(s):  
M. Iwatsuki ◽  
Y. Kokubo ◽  
Y. Harada ◽  
J. Lehman
Keyword(s):  
Electron Microscope ◽  
Structure Analysis ◽  
Organic Materials ◽  
Strong Interactions ◽  
Specimen Preparation ◽  
Great Effort ◽  
Electron Microscopic ◽  
Crystal Fields ◽  
Special Skill ◽  
Long Time

In recent years, the electron microscope has been significantly improved in resolution and we can obtain routinely atomic-level high resolution images without any special skill. With this improvement, the structure analysis of organic materials has become one of the interesting targets in the biological and polymer crystal fields.Up to now, X-ray structure analysis has been mainly used for such materials. With this method, however, great effort and a long time are required for specimen preparation because of the need for larger crystals. This method can analyze average crystal structure but is insufficient for interpreting it on the atomic or molecular level. The electron microscopic method for organic materials has not only the advantage of specimen preparation but also the capability of providing various information from extremely small specimen regions, using strong interactions between electrons and the substance. On the other hand, however, this strong interaction has a big disadvantage in high radiation damage.

A Stationary Solution of High-Energy Electron Reflection (HEER) for An Arbitrary Surface

1990 ◽  
Vol 48 (2) ◽  
pp. 374-375
Author(s):  
YIQUN MA
Keyword(s):  
Stationary Solution ◽  
High Energy ◽  
Bloch Wave ◽  
Dynamical Theory ◽  
High Energy Electron ◽  
Bulk Materials ◽  
Periodic Surface ◽  
Electron Transmission ◽  
Electron Reflection ◽  
Long Time

For a long time, the development of dynamical theory for HEER has been stagnated for several reasons. Although the Bloch wave method is powerful for the understanding of physical insights of electron diffraction, particularly electron transmission diffraction, it is not readily available for the simulation of various surface imperfection in electron reflection diffraction since it is basically a method for bulk materials and perfect surface. When the multislice method due to Cowley & Moodie is used for electron reflection, the “edge effects” stand firmly in the way of reaching a stationary solution for HEER. The multislice method due to Maksym & Beeby is valid only for an 2-D periodic surface.Now, a method for solving stationary solution of HEER for an arbitrary surface is available, which is called the Edge Patching method in Multislice-Only mode (the EPMO method). The analytical basis for this method can be attributed to two important characters of HEER: 1) 2-D dependence of the wave fields and 2) the Picard iteractionlike character of multislice calculation due to Cowley and Moodie in the Bragg case.

Direct imaging of charge transfer

1996 ◽  
Vol 54 ◽  
pp. 680-681
Author(s):  
Yimei Zhu ◽  
J. Tafto
Keyword(s):  
Charge Transfer ◽  
Electron Diffraction ◽  
Scattering Amplitude ◽  
High Temperature Superconductors ◽  
Charge Carriers ◽  
Image Charge ◽  
Net Charge ◽  
Long Time ◽  
Electron Holes ◽  
First Time

The electron holes confined to the CuO2-plane are the charge carriers in high-temperature superconductors, and thus, the distribution of charge plays a key role in determining their superconducting properties. While it has been known for a long time that in principle, electron diffraction at low angles is very sensitive to charge transfer, we, for the first time, show that under a proper TEM imaging condition, it is possible to directly image charge in crystals with a large unit cell. We apply this new way of studying charge distribution to the technologically important Bi2Sr2Ca1Cu2O8+δ superconductors.Charged particles interact with the electrostatic potential, and thus, for small scattering angles, the incident particle sees a nuclei that is screened by the electron cloud. Hence, the scattering amplitude mainly is determined by the net charge of the ion. Comparing with the high Z neutral Bi atom, we note that the scattering amplitude of the hole or an electron is larger at small scattering angles. This is in stark contrast to the displacements which contribute negligibly to the electron diffraction pattern at small angles because of the short g-vectors.

Microstructural characterization of plasma-processed Ti-Al metal matrix composites

1989 ◽  
Vol 47 ◽  
pp. 552-553
Author(s):  
M. G. Burke ◽  
M. N. Gungor ◽  
M. A. Burke
Keyword(s):  
High Temperature ◽  
Titanium Aluminide ◽  
Plasma Processing ◽  
Microstructural Characterization ◽  
High Temperature Strength ◽  
Matrix Composites ◽  
Intermetallic Matrix ◽  
Long Time ◽  
Strength And Stiffness ◽  
Intermetallic Matrix Composites

Intermetallic matrix composites are candidates for ultrahigh temperature service when light weight and high temperature strength and stiffness are required. Recent efforts to produce intermetallic matrix composites have focused on the titanium aluminide (TiAl) system with various ceramic reinforcements. In order to optimize the composition and processing of these composites it is necessary to evaluate the range of structures that can be produced in these materials and to identify the characteristics of the optimum structures. Normally, TiAl materials are difficult to process and, thus, examination of a suitable range of structures would not be feasible. However, plasma processing offers a novel method for producing composites from difficult to process component materials. By melting one or more of the component materials in a plasma and controlling deposition onto a cooled substrate, a range of structures can be produced and the method is highly suited to examining experimental composite systems. Moreover, because plasma processing involves rapid melting and very rapid cooling can be induced in the deposited composite, it is expected that processing method can avoid some of the problems, such as interfacial degradation, that are associated with the relatively long time, high temperature exposures that are induced by conventional processing methods.

Gum arabic helps prepare better lacey polymer films for specimen support in electron microscopy

1993 ◽  
Vol 51 ◽  
pp. 240-241
Author(s):  
Shailesh R. Sheth ◽  
Jayesh R. Bellare
Keyword(s):  
Electron Microscopy ◽  
Polymer Films ◽  
Gum Arabic ◽  
Complete Removal ◽  
Ammonium Bromide ◽  
Release Agent ◽  
Astigmatism Correction ◽  
Long Time ◽  
Micro Holes ◽  
Cetyl Trimethyl Ammonium

Specimen support and astigmatism correction in Electron Microscopy are at least two areas in which lacey polymer films find extensive applications. Although their preparation has been studied for a very long time, present techniques still suffer from incomplete release of the film from its substrate and presence of a large number of pseudo holes in the film. Our method ensures complete removal of the entire lacey film from the substrate and fewer pseudo holes by pre-treating the substrate with Gum Arabic, which acts as a film release agent.The method is based on the classical condensation technique for preparing lacey films which is essentially deposition of minute water or ice droplets on the substrate and laying the polymer film over it, so that micro holes are formed corresponding to the droplets. A microscope glass slide (the substrate) is immersed in 2.0% (w/v) aq. CTAB (cetyl trimethyl ammonium bromide)-0.22% (w/v) aq.

On-line image readout in CTEM

1994 ◽  
Vol 52 ◽  
pp. 400-401
Author(s):  
K.-H. Herrmann ◽  
W. D. Rau ◽  
R. Sikeler
Keyword(s):  
Primary Electron ◽  
Digital Information ◽  
Electron Hole ◽  
Detection Technology ◽  
Long Time ◽  
On Line ◽  
Electron Image ◽  
Optical Transfer ◽  
Detection Quantum Efficiency ◽  
Technical Solutions

Quantitative recording of electron patterns and their rapid conversion into digital information is an outstanding goal which the photoplate fails to solve satisfactorily. For a long time, LLL-TV cameras have been used for EM adjustment but due to their inferior pixel number they were never a real alternative to the photoplate. This situation has changed with the availability of scientific grade slow-scan charged coupled devices (CCD) with pixel numbers exceeding 106, photometric accuracy and, by Peltier cooling, both excellent storage and noise figures previously inaccessible in image detection technology. Again the electron image is converted into a photon image fed to the CCD by some light optical transfer link. Subsequently, some technical solutions are discussed using the detection quantum efficiency (DQE), resolution, pixel number and exposure range as figures of merit.A key quantity is the number of electron-hole pairs released in the CCD sensor by a single primary electron (PE) which can be estimated from the energy deposit ΔE in the scintillator,

Sign in / Sign up

Export Citation Format

Share Document