Growth promoters: reassessing the risk

1991 ◽  
Vol 1991 ◽  
pp. 43-43
Author(s):  
A.R. Peters
Keyword(s):  
Antimicrobial Activity ◽  
Feed Additives ◽  
Growth Promoter ◽  
Therapeutic Action ◽  
Medicinal Products ◽  
Growth Promoters ◽  
Consumer Concerns ◽  
Binding Agents ◽  
Veterinary Medicinal Products

Legislation to control veterinary medicinal products is undergoing continual development in the EEC and UK and therefore the risks are continually reassessed. In the present paper current and future legislation together with consumer concerns both real and imaginary are reviewed.Since the EEC ban on hormonal growth promoter implants in 1986 the remaining legal products are all feed additives. Registration of feed additives in the EEC is controlled under Directive 70/524 and its various amending directives. this directive is concerned with all products added to feed and mainly includes substances used to affect the quality of the feedstuff i.e., emulsifiers, stabilisers, antioxidants, colorants and binding agents and also vitamins and micronutrients. The majority of growth promoters exert their affects by antimicrobial activity and these and certain prophylactic medicinal products such as coccidiostats are also included. All products with a therapeutic action are controlled under the Veterinary Medicine Directives 81/851 and 81/852, quite separate legislation and under the responsibility of a different department within the EEC Coimdssion. However, there is provision under Directive 84/587 amending 70/524 to transfer the medicinal feed additives to 81/851 and 81/852.

scholarly journals VALIDAÇÃO DE MÉTODO ANALÍTICO PARA ANÁLISE DE AMITRAZ EM MEL UTILIZANDO GC/TSD

2018 ◽  
Vol 35 (4) ◽  
pp. 63
Author(s):  
Flavio Soares Silva ◽  
Mary Rosa Rodrigues De Marchi
Keyword(s):  
Limit Of Detection ◽  
Solid Phase ◽  
The European Union ◽  
Medicinal Products ◽  
Analytical System ◽  
Nitrogen Phosphorus Detector ◽  
The City ◽  
Nitrogen Phosphorus ◽  
Veterinary Medicinal Products

This paper describes the validation of method for analysis of the acaricide amitraz in honey using nhexane/acetone extraction, cleanup in cartridge of solid phase extraction (SPE) and analysis by gas chromatography with nitrogen-phosphorus detector (GC -TSD). The method can be used to monitor the presence of the pesticide amitraz in honey because of its good analytical parameters, precision (CV <11%) and accuracy (>80%) in the range of 100-400 ng g-1. The limit set in the European Union, by Committee for Veterinary Medicinal Products, for amitraz in honey  (200 ng g-1) is within this range. The response of the analytical system was linear between 100 and 800 ng mL-1 with correlation coefficient of 0.9996, limit of detection (LD -7 ng g-1) and quantification (LQ -100 ng g-1). The sample was fortified at three concentrations 100 ng g-1, 200 ng g-1 and 400 ng g-1, giving an average recovery of 80, 88 and 92% respectively. The validated method was used to assess the quality of honey sold in the city of Araraquara/SP, in which there were no residues of amitraz.

scholarly journals https://www.anbarjvs.edu.iq/wp-content/uploads/2021/06/1.pdf

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Kifah Odhaib ◽  
Measem Alallawee ◽  
Zainab AL-Mousawi
Keyword(s):  
Animal Feed ◽  
Feed Additives ◽  
Commercial Application ◽  
Growth Promoters ◽  
Animal Product ◽  
Deterioration Process ◽  
Herbal Plants ◽  
Feed Costs ◽  
The Stability

The purpose of this review is to summarize the effectiveness, modes of action and commercial application of herbal plants and their derivatives as growth promoters for animal. As described in literature, the increase in the growth of farming prices and feed costs for small ruminant in general, led to increases difficulties in production of livestock. To dissolve this issue, several studies concentrated on new alternative of feed resource, but others have tried to enrich milk products and meat by rising polyphenol compounds content to their by introductions of herbal plants in sheep and goat feed. Currently, consumers demand safety and the quality of feeding. Since antibiotics can be leave residues in ruminant tissues, that could induce subsequent emergence of resistant strains of microorganisms capable of endangering the health of livestock and human. This scenario has given the impetus to explore alternatives to antibiotics in animal nutrition. Consequently, as replacement for the synthetic growth promoter’s antibiotics, natural products like herbs and spice as natural feed additives come to the attention to enhance physiological functions. So, the use of feeds containing bioactive compounds such as thymol, flavonoids, saponins, limonene, thymoquinone, essential oils and others which concentrated in different parts, such as leaves, roots and seeds that can be used for these purpose in animal feed and responsible for the healthy animal product. Furthermore, one of the hot points in the advanced research is the stability of animal product against the oxidative deterioration process that limits the shelf life.

scholarly journals The Effect of α-Monolaurin and Butyrate Supplementation on Broiler Performance and Gut Health in the Absence and Presence of the Antibiotic Growth Promoter Zinc Bacitracin

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 651
Author(s):  
Bakang R. Letlole ◽  
Ellen P. C. W. Damen ◽  
Christine Jansen van Rensburg
Keyword(s):  
Bacterial Resistance ◽  
Feed Additives ◽  
Growth Promoter ◽  
Gut Health ◽  
Feed Conversion ◽  
Growth Promoters ◽  
Broiler Performance ◽  
Positive Effects ◽  
Zinc Bacitracin ◽  
The Impact

The use of antibiotic growth promoters (AGP) is common practice to improve broiler production and performance. The use of AGP is under discussion as it can induce bacterial resistance. The purpose of this study was to determine the impact of removing AGP from broiler feed and study the effect of feed additives. For those countries where in-feed AGP are still permitted, the effect of the products in the presence of AGP was evaluated. Half the number of male broilers received a diet free of AGP, whereas the other half received a diet supplemented with zinc bacitracin at 0.5 g/kg. Both diets were either without additional additives or combined with a coated sodium butyrate, α-monolaurin or a combination of these additives. Raised under optimal conditions, the incorporation of AGP had no effect on broiler performance, but negatively affected villi height and villi height to crypt depth (VH:CD) ratio in the duodenum. In the absence of AGP, butyric acid and α-monolaurin had a positive effect on villi height. In the presence of AGP, α-monolaurin resulted in the lowest feed conversion ratio and improved VH:CD ratio in the duodenum, jejunum and ileum. Both feed additives had minimal effect on performance parameters but showed small positive effects on gut health in the absence of AGP and could play a role in the strategy to replace AGP.

scholarly journals ВДОСКОНАЛЕННЯ СИСТЕМИ КОНТРОЛЮ ТА ОБІГУ ГМО В УКРАЇНІ

2016 ◽  
Vol 18 (3(71)) ◽  
pp. 63-65
Author(s):  
B.I. Nazar
Keyword(s):  
Genetically Modified Organisms ◽  
Genetically Modified ◽  
The State ◽  
Feed Additives ◽  
Integrated System ◽  
Medicinal Products ◽  
State Monitoring ◽  
State Registration ◽  
The Impact ◽  
Veterinary Medicinal Products

The article briefly presents the main approaches to the state registration and order of the state veterinary and sanitary expertise GMO sources of feed, feed additives and veterinary medicinal products are listed feasibility studies to be carried out at the registration of GMO sources listed safety parameters on which the assessment of GMO sources. There need to conduct clinical studies to determine the impact of GMO sources or feed sources, feed ingredients derived from their use on animals. The order defines the procedure for state registration of genetically modified organisms sources of feed, feed additives and veterinary medicinal products containing genetically modified organisms or derived from their use.The basic components and objectives of the integrated system of state monitoring of GMO sources of feed, feed additives, premixes for livestock and poultry. The basic methodological approaches and criteria for the development and implementation in Ukraine of the State monitoring of feed containing GMO sources including requirements for sampling, setting the frequency of sampling and analysis of risks at all stages of the chain «production – consumption» . Based on the analysis of a draft list of feeds, feed raw materials and premixes that must be controlled on content of genetically modified organisms. 

scholarly journals Use of Bacillus Subtilis Probiotics as Non-Antibiotic Gut Modulator and Growth Promoter in Broiler Chickens

2021 ◽  
Author(s):  
Arbab Sikandar
Keyword(s):  
Bacillus Subtilis ◽  
Immune System ◽  
Broiler Chickens ◽  
Feed Additives ◽  
Growth Enhancement ◽  
Growth Promoter ◽  
Growth Promoters ◽  
Normal Microflora ◽  
Intestinal Pathogens ◽  
Gut Mucosa

Wide range of Antibiotics is being used as feed additives in Animal industry in order to get rid from pathogens and as growth promoters in developing world. But after the suggested prohibition on using antibiotics, products such as probiotics are getting substantial importance in nutrition because of their non-resistant and non-residual possessions. Basic aim of the chapter is to highlight fruitful effects of Bacillus Subtilis as non-antibiotic gut modulator and growth promoter in broiler chickens. Probiotics are the living culture of microorganisms. They flourish in the gut of the host and fortify the growth of valuable commensals in the digestive tract by minimizing the destruction triggered by pathogens, boost up the immune system, supporting the integrity of the gut mucosa and maintain a stability and balance of normal microflora. Probiotics can be used as best substitute to conventional antimicrobial therapy. In addition, it has been observed that probiotics plays a role in growth enhancement by augmenting useful enzymes in the body and promote the growth of other normal commensals such as Lactobacillus and having effect on gut luminal pH. Probiotics are quite active against intestinal pathogens in several ways, viz. including improved immune elimination, competing for mucosal attachment, striving for crucial nutrients, or producing antimicrobial complexes contrary to numerous enteropathogens. It can be concluded that B. Subtilis has the ability to modulate gut and immune system histophysiology and histomorphology and can be used as safe antimicrobial candidate in poultry nutrition. Knowledge of such possessions of the B. Subtilis as probiotics and the mechanisms of action may enable the researchers to manipulate the use of such alternatives for better growth production, and safe and healthy poultry industry.

scholarly journals Dietary Supplementation of Inorganic, Organic, and Fatty Acids in Pig: A Review

Animals ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1740
Author(s):  
Giulia Ferronato ◽  
Aldo Prandini
Keyword(s):  
Fatty Acids ◽  
Gastrointestinal Tract ◽  
Organic Acids ◽  
Pathogenic Bacteria ◽  
Tricarboxylic Acid Cycle ◽  
Antimicrobial Properties ◽  
Feed Additives ◽  
Feed Additive ◽  
Growth Promoter ◽  
Growth Promoters

Reduction of antibiotic use has been a hot topic of research over the past decades. The European ban on growth-promoter use has increased the use of feed additivities that can enhance animal growth performance and health status, particularly during critical and stressful phases of life. Pig farming is characterized by several stressful periods, such as the weaning phase, and studies have suggested that the proper use of feed additives during stress could prevent disease and enhance performance through modulation of the gastrointestinal tract mucosa and microbiome. The types of feed additive include acids, minerals, prebiotics, probiotics, yeast, nucleotides, and phytoproducts. This review focuses on commonly used acids, classified as inorganic, organic, and fatty acids, and their beneficial and potential effects, which are widely reported in the bibliography. Acids have long been used as feed acidifiers and preservatives, and were more recently introduced into feed formulated for young pigs with the goal of stabilizing the stomach pH to offset their reduced digestive capacity. In addition, some organic acids represent intermediary products of the tricarboxylic acid cycle (TCA), and thus could be considered an energy source. Moreover, antimicrobial properties have been exploited to modulate microbiota populations and reduce pathogenic bacteria. Given these potential benefits, organic acids are no longer seen as simple acidifiers, but rather as growth promoters and potential antibiotic substitutes owing to their beneficial action on the gastrointestinal tract (GIT).

scholarly journals Dietary medicinal plants enhance the chemical composition and quality of broiler chicken meat

2020 ◽  
Vol 70 (4) ◽  
pp. 1823 ◽  
Author(s):  
T. TASHLA ◽  
N. PUVAČA ◽  
D. LJUBOJEVIĆ PELIĆ ◽  
R. PRODANOVIĆ ◽  
J. BOŠKOVIĆ ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Meat Quality ◽  
Black Pepper ◽  
Chicken Meat ◽  
Feed Additives ◽  
Piper Nigrum ◽  
Hot Pepper ◽  
Growth Promoter ◽  
Caloric Value

The use of nutritional strategies to improve the quality of meat is a relatively new approach that has emerged at the interface of animal science and food science. The effects of dietary medicinal plants (Allium sativum L., Piper nigrum L., and Capsicum annuum L.) addition to chicken nutrition on quality characteristics of breast and thigh with drumstick meat, as well as caloric value of chicken meat were investigated. Quality measurements included meat sensory (colour, smell, taste, softness, chewiness, juiciness and overall impression), physical (pH, colour-CIE L*a*b* and drip-loss) and chemical (moisture, protein, fat and ash content) characteristics. Herbs showed significant (P < 0.05) influence in altering most examined quality parameters of chicken meat, especially when adding red hot pepper. Caloric value of chicken meat was improved which makes garlic, black pepper and hot red pepper valuable natural feed additives in improvement of meat quality as well as a natural growth promoter. In conclusion, herbs had positive influence on chicken meat quality, however the knowledge of their mode of action is still limited and thus requires further investigation.

scholarly journals Nanotechnology and its Considerations in Poultry Field: An Overview

2019 ◽  
Vol 70 (3) ◽  
pp. 1611 ◽  
Author(s):  
W.A. ABD EL-GHANY
Keyword(s):  
Positive Influence ◽  
Feed Additives ◽  
Growth Promoters ◽  
Science Field ◽  
Beneficial Effects ◽  
To Come ◽  
Chicken Eggs ◽  
Embryonated Chicken ◽  
Poultry Farming

Nanotechnology is an emerging science field that in the years to come could have countless beneficial effects on every aspect of everyday life including animal farming. Recently, research in this sector has shown the potential for many different applications in Veterinary practice. In poultry farming in particular, various nanoparticles have been experimentally used for several purposes such as: alternative to antibiotics as growth promoters, as feed additives to enhance and improve the growth rate, performance, immunity, resistance to pathogens and increase the quality of meat. In laying hens, they can have a positive influence to both quantity and quality of eggs. Moreover, nanomaterials applied in embryonated chicken eggs can improve embryos development. The aim of this overview is to provide a description of potential nanotechnology applications for poultry sector and discuss any challenges or obstacles including the matters of safety of application of these nanomaterials in animals, in humans and of course in the environment.

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