Adiponectin and leptin levels in migraineurs: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

2020 ◽  
Vol 3 ◽  
pp. 251581632096696
Author(s):  
Alessandra C Goulart ◽  
Bianca de Almeida-Pititto ◽  
Paulo A Lotufo ◽  
Itamar S Santos ◽  
Sandra RG Ferreira ◽  
...  

Background: Relationships of adipokines (ADP) with migraine are not well-established. We examined the relationship of adiponectin and leptin with migraine by aura symptoms. Methods: In a baseline cross-sectional data of Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), associations of ADP levels and migraine were assessed in a sample of 257 nondiabetic subjects, free from cardiovascular disease. Associations of ADP tertiles (dependent variable) and migraine status were tested using logistic regression models. Categories of migraine were created as follows: no headache (reference), migraine with aura (MA), and migraine without aura (MO) in all sample and by sex. Odds ratio (OR) with respective 95% confidence interval (CI) adjusted for age, sex, body mass index, and metabolic syndrome. Results: Among participants (46 years ± SD: 4.8), 47.5% were women and 36.2% had migraine (16.7% MA). Median values of leptin (ng/mL) increased gradually across subgroup: no headache: 9.5 (interquartile range (IQR): 5.5–15.7) versus MO: 17.0 (IQR: 10.9–34.2) versus MA: 20.9 (IQR: 11.7–29.3), overall p value <0.0001, but not for adiponectin levels. After full adjustment, the third of leptin was positively associated with MA (OR 2.89 (1.00–8.4)) and the second of adiponectin was associated with MO (OR 2.76; 95% CI: 1.09–6.96, p = 0.03). Positive associations with MA, second (OR 3.81; 95% CI: 1.07–13.59; p = 0.04) and third tertile of leptin (6.54; 95% CI: 1.74–24.57, p = 0.005), were also observed in women, but not in men. Conclusions: Positive associations between ADP and migraine, particularly between MA and leptin levels in women, raise the possibility of adipocytokines and play a role in migraine pathophysiology.

2018 ◽  
Vol 3 (3) ◽  
pp. 500
Author(s):  
Desmariyenti Desmariyenti ◽  
Nelfi Sarlis ◽  
Rima Fitriani

<p><em>Good weaning time is done at the age of the child reaches 2 years. Weaning at less</em><em> </em><em>than 2 years of age can cause problems in children such as incidence of infectious diseases, especially increased diarrhea, nutritional effects that lead to malnutrition in children and cause the relationship of children and mothers is reduced </em><em>closeness </em><em>because bounding attachment process is disrupted. This study aims to determine the relationship between knowledge  and  attitude  of  the  mother  with  the  decision  of  weaning  time  in</em><em> </em><em>Tangkerang Timur Work Area Puskesmas Tenayan Raya. This research was conducted in </em><em>Mei</em><em>-</em><em>J</em><em>uni 2017 and this research using research type is quantitative data with research design  using  cross  sectional.  Sampling  technique  using  Stratified  random  sampling, population in this study amounted to 368 people and samples 18</em><em>4</em><em> p</em><em>e</em><em>ople in East Tangkerang Village. The analysis used is univariate and bivariate. The result of this research is can be concluded that there is significant relation between knowledge with time weaning (p-value 0,000 &lt;0,05), there is significant relation between attitude with time weaning (p-value 0,000 &lt;0,05). Mothers exclusively breastfeed to their babies until 6 months of age and and continue with breastfeeding until 24 months of age.</em><em></em></p><p> </p><p>Waktu penyapihan yang baik dilakukan pada usia anak mencapai 2 tahun. Penyapihan yang dilakukan pada usia kurang dari 2 tahun dapat menyebabkan masalah pada anak seperti insiden penyakit infeksi terutama diare meningkat, pengaruh gizi yang mengakibatkan malnutrisi  pada  anak  dan  menyebabkan  hubungan  anak  dan  ibu  berkurang  keeratannya karena proses bounding attachment terganggu. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan dan sikap ibu dengan keputusan waktu penyapihan di Keluraan Tangkerang Timur Wilayah Kerja Puskesmas Tenayan Raya. Penelitian ini dilakukan pada bulan Mei-Juni tahum 2017 dan penelitian ini menggunakan jenis penelitian adalah data kuantitatif dengan  desain penelitian menggunakan  cross sectional. Teknik sampling menggunakan Stratified random sampling, Populasi dalam penelitian ini berjumlah 368 orang dan sampel 184 orang di Kelurahan Tangkerang Timur. Analisa yang diunakan adalah univariat dan bivariat. Hasil penelitian didapatkan bahwa ada hubungan bermakna antara pengetahuan dengan waktu penyapihan (p-value 0,000&lt; 0,05), ada   hubungan   bermakna   antara   sikap   dengan   waktu   penyapihan   (p-value   0,000   &lt;0,05). Diharapkan ibu memberikan ASI eksklusif pada bayinya sampai usia 6 bulan dan dan dilanjutkan dengan MPASI sampai usia 24 bulan.</p>


Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1461
Author(s):  
Andrea Polanco ◽  
Brenda McCowan ◽  
Lee Niel ◽  
David L. Pearl ◽  
Georgia Mason

Laboratory monkey ethograms currently include subcategories of abnormal behaviours that are based on superficial morphological similarity. Yet, such ethograms may be misclassifying behaviour, with potential welfare implications as different abnormal behaviours are likely to have distinct risk factors and treatments. We therefore investigated the convergent validity of four hypothesized subcategories of abnormal behaviours (‘motor’, e.g., pacing; ‘self-stimulation’, e.g., self-sucking; ‘postural’, e.g., hanging; and ‘self-abuse’, e.g., self-biting). This hypothesis predicts positive relationships between the behaviours within each subcategory. Rhesus macaque (Macaca mulatta) data on 19 abnormal behaviours were obtained from indoor-housed animals (n = 1183). Logistic regression models, controlling for sex, age, and the number of observations, revealed that only 1/6 ‘motor’ behaviours positively predicted pacing, while 2/3 ‘self-abuse’ behaviours positively predicted self-biting (one-tailed p-value < 0.05). Furthermore, ‘self-stimulation’ behaviours did not predict self-sucking, and none of the ‘postural’ behaviours predicted hanging. Thus, none of the subcategories fully met convergent validity. Subsequently, we created four new valid subcategories formed of comorbid behaviours. The first consisted of self-biting, self-hitting, self-injurious behaviour, floating limb, leg-lifting, and self-clasping. The second comprised twirling, bouncing, rocking, swinging, and hanging. The third comprised pacing and head-twisting, while the final subcategory consisted of flipping and eye-poking. Self-sucking, hair-plucking, threat-biting, and withdrawn remained as individual behaviours. We encourage laboratories to replicate the validation of these subcategories first, and for scientists working with other species to validate their ethograms before using them in welfare assessments.


2020 ◽  
Vol 5 (1) ◽  
pp. 36-42
Author(s):  
Yeviza Puspitasari

Hyperbilirubinemia is one of the clinical phenomena most often found in neonates occurring in the first week of life, which is also one of the factors causing infant death is influenced by the immature liver function of the baby to process erythrocytes (red blood cells), resulting in the accumulation of bilirubin. The purpose of this study was to determine the relationship of birth weight of infants with the incidence of hyperbilirubinemia in RSUD dr. Ibnu Soetowo Baturaja Ogan Komering Ulu Regency in 2019. This study uses analytic methods with a cross-sectional approach. The study population was all infants aged 0-7 days in the neonatal room at RSUD dr. Ibnu Soetowo Baturaja Ogan Komering Ulu Regency in 2019, with a random sampling. Data analysis uses univariate analysis and bivariate analysis using distribution tables and Chi-Square statistical tests, with a 95% confidence level. In the univariate analysis, of 203 respondents found 26.5% had hyperbilirubinemia and those without hyperbilirubinemia 72.5%, 24.6% of infants with LBW and non-LBW infants 75.4%. Bivariate analysis showed that there was an LBW relationship with the incidence of hyperbilirubinemia (p-value 0,000).


2018 ◽  
Vol 7 (1) ◽  
pp. 68
Author(s):  
Aris Winandar

HUBUNGAN PENGETAHUAN, PERSEPSI, DAN SIKAP DENGAN INTENSITAS PERILAKU MEROKOK PADA MAHASISWA AKADEMI FARMASI DAN MAKANAN (AKAFARMA) YAYASAN HARAPAN BANGSA BANDA ACEH TAHUN 2016     Aris Winandar 1.Fakultas Kesehatan Masyarakat Universitas Serambi Mekkah Banda Aceh Email korespondensi : ( [email protected])   Abstrak   Latar Belakang : Intensitas perilaku merokok juga menimbulkan dampak negatif bagi perokok pasif. Berdasarkan studi pendahuluan yang penulis lakukan di Akademi Farmasi dan Makanan (Akafarma) Yayasan Harapan Bangsa Banda Aceh tahub 2016 jumlah mahasiswa sebanyak 150 orang, sebagian mahasiswa terutama laki-laki mengkonsumsi rokok dalam kesehariannya, penyebab mahasiswa mengkonsumsi rokok karena ingin tampil gaya, alasan mereka jika merokok membuat pikaran jadi lebih tenang, selain itu sikap mahasiswa yang tidak mengetahui bahwa jika merokok membuat mereka mudah terkena penyakit, selain itu kurangnya pengetahuan tentang rokok juga merupakan salah satu penyebab mahasiswa tidak memperdulikan keesehatannya..(Tujuan) untuk mengetahui hubungan pengetahuan, persepsi, dan sikap dengan intensitas perilaku merokokpada remaja putra di Akademi Farmasi dan Makanan (Akafarma) Yayasan Harapan Bangsa Banda Aceh Tahun 2016. Metode : bersifat deskriptif analitik dengan pendekatan crossectional study.Hasil : ada hubungan yang bermakna antara pengetahuan dengan intensitas perilaku merokokdengan p value=0,000 (p<0,05), persepsi p value=0,004 (p<0,05), dan sikap dengan p value=0,002 (p<0,05) dengan intensitas perilaku merokok pada mahasiswa di Akademi Farmasi dan Makanan (Akafarma) Yayasan Harapan Bangsa Banda Aceh.Kesimpulan : Pengetahuan, Persepsi, Dan Sikap ada hubungan yang sangat bermakna dengan intensitas perilaku merokok pada mahasiswa di Akademi Farmasi dan Makanan (Akafarma) Yayasan Harapan Bangsa Banda Aceh   Kata kunci: Perilaku Merokok, remaja   Abstract   Background: The intensity of smoking behavior also has a negative impact on passive smoking. Based on preliminary study which the author did at Academy of Food and Pharmacy (Akafarma) Harapan Bangsa Foundation Banda Aceh in 2016 the number of students as many as 150 people, some students, especially men consume cigarettes in their daily life, the cause of students consuming cigarettes because they want to look stylish, their reasons if smoking makes the plateau so calm, besides the attitude of students who do not know that if smoking makes them susceptible to disease, other than that the lack of knowledge about cigarettes is also one cause the students do not care about his health ..(Goal) to know the relationship of knowledge, and attitudes with the intensity of smoking behavior in young men at the Akademi Academy of Pharmacy and Food (Akafarma) Harapan Bangsa Foundation Banda Aceh Year 2016. Method: analytical descriptive with cross-sectional approach. Result: there is a significant correlation between knowledge and intensity of smoking behavior with p value = 0,000 (p <0,05), perception p value = 0,004 (p <0,05), and attitude p value = 0,002 (p <0,05) with intensity of smoking behavior among students at Akademi Academy of Pharmacy and Food (Akafarma) Harapan Bangsa Foundation Banda Aceh. Conclusion: Knowledge, Perception, And Attitude There is a very meaningful relation with intensity of smoking behavior in students at the Akpararma Akademarma dan Food (Akafarma) Foundation of Harapan Bangsa Banda Aceh   Keywords: Smoking Behavior, adolescents


2018 ◽  
Vol 2 (1) ◽  
pp. 117
Author(s):  
Rendika Baharudin Abror ◽  
Cholik Harun Rosjidi ◽  
Rika Maya Sari

AbstractEach child has a task that must be passed well, especially at the age of the child (12-36 months). One of the developmental tasks in toddlers is toilet training. Long-term use of diapers can cause toilet effects. This study aims to determine the relationship between diapers with the ability of toileting in children.The design of this research is Correlation with cross sectional approach. Large sample of 70 respondents. Sampling of the study using total sampling, data collection using questionnaires and calculations using Chi-square Correlation test using SPSS 16.0 error α 0.05.The results of the research variables The use of diapers in children interpreted most of the 47 children of respondents (67.1%) Did not use and almost half of the 23 respondents (32.9%) use. The ability of toileting in children is interpreted by most of the 42 respondents (60.0%) fulfilled, and almost half of 28 respondents (40.0%) are not met.Based on the calculation of Chi-square SPSS statistic shows that p value 0,000 <0,05) means that there is relationship of diaper usage with the ability of toileting in children with the closeness of cc relationship of 0.479 enough category.The results of this study concluded that almost half of them use diapers, and almost half of them do not meet the ability of toileting, the researcher suggests in the research place to put a picture or leaflet about the effect of Diaper Usage on Toileting Ability so that the wise mother in using Diapers.Keywords: diapers, toileting, children AbstrakSetiap anak mempunyai tugas perkembangan yang harus dilewati dengan baik, terlebih pada usia toddler (12-36 bulan). Salah satu tugas perkembangan pada anak usia toddler adalah toilet training. Pemakaian diapers dalam jangka panjang dapat menimbulkan efek yang berbahaya serta bisa menghambat kemampuan toilet training anak. Penelitian ini bertujuan untuk mengetahui Hubungan Penggunaan diapers dengan kemampuan toileting pada anakDesain penelitian ini adalah Korelasi dengan pendekatan cross sectional. Besar sampel 70 responden. Sampling penelitian menggunakan Total sampling, pengumpulan data menggunakan kuesioner dan perhitungan menggunakan uji Korelasi Chi-square dengan menggunakan SPSS 16.0 kesalahan α 0,05.Hasil penelitian variabel Penggunaan diapers pada anak diinterpretasikan sebagian besar 47 anak responden (67,1%) Tidak menggunakan dan hampir setengahnya 23 responden (32,9%) menggunakan. Pada kemampuan toileting pada anak diinterpretasikan sebagian besar 42 responden (60,0%) tercapai, dan hampir setengahnya 28 responden (40,0%) belum tercapai.Berdasarkan perhitungan uji statistik Chi-square SPSS menunjukkan p value 0,000< 0,05) artinya ada hubungan penggunaan diapers dengan kemampuan toileting pada anak dengan keeratan hubungan cc sebesar 0,479 kategori cukupHasil penelitian disimpulkan hampir setengahnya menggunakan diapers, dan hampir setengahnya belum tercapai kemampuan toileting maka peneliti menyarankan pada tempat penelitian untuk memasang gambar atau leaflet tentang dampak Penggunaan Diapers Terhadap Kemampuan Toileting, sehingga ibu bijak dalam menggunakan Diapers.Kata kunci: Diapers, Toileting, Anak.


2020 ◽  
Vol 11 (1) ◽  
pp. 110-119
Author(s):  
Julianto Julianto ◽  
Izma Daud ◽  
Sari Milyati

Abstrak  Latar Belakang :Access block adalah situasi dimana pasien yang mengalami lama rawat di IGD 6 karena kurangnya akses ke ruang rawat inap dan kepadatan jumlah pasien yang tidak terkendali, dampaknya ditemukan bahwa semakin lama access block  semakin tinggi pula perburukan pasien dalam 24 jam.Tujuan : ini bertujuan untuk mengetahui hubungan access block dengan perburukan kondisi pasien di Instalasi Gawat Darurat RSUD Ulin Banjarmasin.Metode :Penelitian menggunakan desain analitik dengan pendekatan cross sectional. Jumlah sampel yang diambil berjumlah 40 orang dengan teknik pengambilan accidental sampling. Analisis data melalui uji spearman rank.Hasil : Hasil uji dipapatkan nilai p hitung 0,000 (0,05) ada hubungan antara access block dengan perburukan kondisi pasien di instalasi gawat darurat RSUD Ulin Banjarmasi.Simpulan: Berdasarka hasil penelitian Ada hubungan antara access block dengan perburukan kondisi pasien di Instalasi Gawat Darurat RSUD Ulin Banjarmasin dengan nilai P= 0,000 nilai α = 0,05 dengan nilai koefisien korelasi 0,588 Kata kunci: Access Block, Perburukan Pasien. Abstract Background :Access block is a situation where patients who experience length of stay in the ED 6 due to lack of access to the inpatient room and uncontrolled density of patients, it is found that the longer the access block the higher the deterioration of patients in 24 hours.Purpose: This study aims to determine the relationship of access block with deteriorating condition of patients in Emergency Installation Ulin Hospital Banjarmasin.Method : The research method uses an analytical design with a cross sectional approach. The number of samples taken is 40 people using the accidental sampling technique. Data analysis through spearman rank test.Result: The test results obtained p value calculated 0,000 (0.05) there is a relationship between the access block and deterioration of the patient's condition at the Ulin Banjarmasin Hospital emergency department.Conclusion: Based on the results of the study, there is a relationship between the access block and the worsening of the patient's condition at the Emergency Department of RSUD Ulin Banjarmasin with a value of P = 0.000 value α = 0.05 with a correlation coefficient value of 0.588. Keywords: Access Block, Patient worsening 


2020 ◽  
Vol 2 (1) ◽  
pp. 31-36
Author(s):  
Wa Ode Hajrah ◽  
Niken Purbowati ◽  
Novia Nuraini

erineal rupture needs attention because it can cause dysfunction of the female reproductive organs, as a source of bleeding, a source, or a way in and out of infection, then it can cause death due to bleeding or sepsis. About 85% of Women who delivery vaginally experience perineal rupture, in the age group 25-30 years 24%, while in maternal age 32-39 years by 62%. In Asia, perineal rupture is also a problem in society, 50 % of the world's occurrence is in Asia. The study aims to determine the relationship of maternal factors to the position of the second stage labor and perineal rupture occurrence. This research applied a descriptive-analytic method using a cross-sectional research design. The research sample was 102 respondents, accidental random sampling, which was all labor with perineal rupture in July to November 2018. Statistical tests used chi-square. The results of perineal rupture with maternal age was p-value 0.042 (p <0.05), perineal rupture with maternal parity was p-value 0.01 (p <0.05). Suggestions for various maternal positions in maternity and ANC classes to prevent perineal rupture.


2020 ◽  
Vol 9 (2) ◽  
pp. 102
Author(s):  
Idayati Idayati ◽  
Diny Vellyana ◽  
Sondang Sondang

AbstractHaving treatment in a hospital (hospitalization) is an unpleasant and threatening experience for everyone, especially for children who are still in the process of growth and development. One way to resolve this problem is to use therapeutic communication effectively which will and will be carried out nursing actions. To communicate with children, special approaches or techniques are needed so that the relationship can run well according to the child's growth and development. One of the predisposing factors according to Lawrencen Green's theory is knowledge, when a nurse has good knowledge, her ability in therapeutic communication will be good too. The aim of study is to determine the relationship of knowledge with the therapeutic communication skills of nurses in pediatric patients. This research uses survey analytic methode with crosssectional. Sample in the study were 66 nurses in inpatient rooms of Graha Husada Hospital,technique purposive samplingfor sampling.Data analysis using the Spearman Rank (Rho) correlation test with a significance level (α = 0.05)  is obtained p value 0.025 (p <0.05). There is relationship of knowledge with therapeutic communication ability of nurses in pediatric patients treated at Graha Husada Hospital  Bandar Lampung. Nurses are expected to be able to improve services in providing nursing care to pediatric patients, especially preschool age pediatric patients. AbstrakBerobat di rumah sakit (hospitalisasi) merupakan pengalaman yang tidakmenyenangkan dan mengancam bagi setiaporang,terutama bagi anak – anak yang masih dalam proses tumbuh kembang. Salah satu cara untuk mengatasi masalah tersebut adalah dengan menggunakan komunikasi terapeutik secara efektif yang akan dilakukan tindakan keperawatan. Untuk berkomunikasi dengan anak diperlukan pendekatan atau teknik khusus agar hubungan dapat berjalan dengan baik sesuai dengan tumbuh kembang anak. Salah satu faktor predisposisi menurut teori Lawrence Green adalah pengetahuan, bila perawat memiliki pengetahuan yang baik maka kemampuannya dalam komunikasi terapeutik juga akan baik. Tujuan penelitian ini untuk mengetahui hubungan pengetahuan dengan keterampilan komunikasi terapeutik perawat pada pasien anak. Penelitian ini menggunakan metode survey analitik dengan pendekatan cross sectional. Sampel dalam penelitian ini adalah 66 perawat ruang rawat inap Rumah Sakit Graha Husada dengan teknik pengambilan sampel purposive sampling. Analisis data menggunakan uji korelasi Spearman Rank (Rho) dengan tingkat signifikansi (α = 0.05) diperoleh dari niai p 0.025 (p<0.05). Ada hubungan pengetahuan dengan kemampuan komunikasi terapeutik perawat pada pasien anak yang di rawat di RS Graha Husada Bandar almpung. Perawat diharapkan mampu meningkatkan pelayanan dalam memberikan asuhan keperawatan kepada pasien anak khususnya pasien anak usia prasekolah.


Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Sharrelle Barber ◽  
Joanna Guimarães ◽  
Cardoso Leticia ◽  
Devlin Amie ◽  
Janeway Granche ◽  
...  

Introduction: The prevalence of type-2 diabetes is increasing globally with the sharpest increases occurring in low and middle-income countries. Residential segregation results in increased exposure to adverse neighborhood environments that may inhibit the successful management of diabetes. Moreover, due to historical and contemporary forms of structural racism, marginalized racial groups are more likely to live in these environments. Using a spatial measure of neighborhood-level economic residential segregation (hereafter, segregation) we examined the association between segregation and uncontrolled diabetes in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Methods: The sample included 828 Black, Brown/Mixed-Race, and White participants ages 35-74 with diagnosed diabetes and complete, geocoded information from the baseline examination of ELSA-Brasil (2008-2010). Residential segregation was based on data from the 2010 IBGE demographic census and calculated for study-defined neighborhoods using the local G i * statistic— a spatially weighted z-score that represents how much a neighborhood’s income composition deviates from the larger metropolitan area. Uncontrolled diabetes was based on 2017 ADA criteria and defined as HbA1c ≥ 7%. Multivariable logistic regression models were used to test cross-sectional associations between segregation and uncontrolled diabetes. Results: Black and Brown participants were more likely than Whites to live in highly segregated neighborhoods. The prevalence of uncontrolled diabetes increased across low, medium, and high levels of segregation (23.1% vs. 37.8% vs. 47.7%, respectively). In multivariable models adjusting for age, gender, race, education, income, and study site, segregation was positively associated with uncontrolled diabetes (OR: 1.20, 95% CI: 1.07-1.56). The association was attenuated but remained statistically significant in models adjusting for neighborhood characteristics, behavioral risk factors and time since diabetes diagnosis. (OR: 1.16; 95% CI: 1.05-1.28). In models that included segregation as a categorical variable, individuals living in highly segregated neighborhoods had a 2-fold higher risk of uncontrolled diabetes compared to individuals living in less segregated neighborhoods (High Segregation, OR: 2.20, 95% CI: 1.35-3.58; Medium Segregation, OR: 1.65, 95% CI: 1.08-2.51). Conclusions: Residential segregation may lead to disparate diabetes-related morbidity among urban-dwelling adults in Brazil. Moreover, the disproportionate clustering of Blacks and Browns within segregated neighborhoods implicates segregation as a potential driver of racial inequalities in these outcomes. Policies and/or structural interventions designed to improve neighborhood conditions may be viable strategies to improve the management of diabetes in this setting.


2018 ◽  
Vol 18 (1) ◽  
pp. 73-82
Author(s):  
Firman Edigan ◽  
Deny Pratama Putra

[ID] PT PLN Rayon Tembilahan adalah perusahaan yang bergerak di bidang penyediaan tenaga listrik, pada penelitian awal terdapat pekerja pada shift siang masih banyak pekerja yang tidak menggunakan APD dengan lengkap sesuai dengan bagian pekerjaanya. Tujuan penelitian ini untuk mengetahui hubungan pengetahuan pekerja, kondisi lingkungan, ketersediaan sarana, pengawasan terhadap penggunaan APD pada pekerja teknisi mesin di PT PLN Rayon Tembilahan. Metode penelitian yang digunakan adalah penelitian kuantitatif dengan desain penelitian Cross Sectional. Sampel dalam penelitian ini menggunakan total sampling dimana pekerja teknisi mesin di PT PLN Rayon Tembilahan yang berjumlah 35 orang. Analisis data secara univariat dan bivariat dengan uji-square. Hasil penelitian yang diperoleh tidak ada hubungan pengetahuan dengan penggunaan APD dengan nilai p=0,899, adanya hubungan kondisi lingkungan dengan penggunaan APD dengan nilai p=0,022 dan diperoleh nilai OR=8,500, adanya hubungan sarana prasarana  dengan penggunaan APD dengan nilai p=0,031 dan diperoleh nilai OR=6,857, tidak ada hubungan pengawasan dengan penggunaan APD dengan nilai p=0,854 dan diperoleh nilai OR=1,429. Diharapkan kepada pihak PLN Rayon Tembilahan agar memperihatikan kondisi lingkungan kerja  dan bisa melengkapi sarana prasarana untuk pekerja agar dapat mengurangi resiko terhindar dari kecelakaan kerja. [EN] PT PLN Rayon Tembilahan is a company in the provision of electric power, In the initial study there are workers in the afternoon shift there are still many workers who do not use the complete PPE related with their work, the purpose of this study to determine the relationship of worker knowledge, environmental conditions, the availability of facilities, supervision of the use of PPE on workers in the engine technician PT PLN Rayon Tembilahan. The research method used is quantitative research with Cross Sectional research design. The sample in this research use total sampling where machine technician workers in PT PLN Rayon Tembilahan which amounted to 35 person. Univariate and bivariate data analysis with square test. The result of this research is no correlation with the use of PPE with p = 0,899, there is relation of environmental condition with PPE usage with p value = 0,022 and obtained value OR = 8,500, there is correlation of facility of infrastructure by using PPE with p value = 0,031 and Value OR = 6.857, there is no relationship of supervision with the use of PPE with the value p = 0.854 and obtained the value OR = 1.429. It is expected to PLN Rayon Tembilahan to envisage the condition of the work environment and can equip the infrastructure for workers to reduce the risk of avoidance of work accident.  


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