scholarly journals Perbedaan kadar caffeic acid phenethyl ester pada propolis ekstrak etanol dan propolis ekstrak air

2013 ◽  
Vol 11 (2) ◽  
pp. 43-47
Author(s):  
RIANI DWI HASTUTI ◽  
DIDING PRASETYO ◽  
SRI HARTATI HADINOTO

Hastuti RD, Prasetyo D, Hadinoto SH. 2013. The difference of caffeic acid phenethyl ester level in ethanol extract propolis and water extract propolis. Biofarmasi 11: 43-47. Propolis is a natural product derived from plant resin collected by honeybeen and its composition has wide range of biological activity. CAPE is the ester of caffeic acid, a derivative of phenolic acid, a flavonoid-like compound, one of the major components of propolis. CAPE is reported can protect nephrotoxicity due to cisplatin induction, inhibiting the growth of various types of abnormal cells, having an anti-inflammation activity, antioxidant activity, cyclooxygenase activity, vasodilatation activity in rat aorta, potential inhibitor of nitric oxidant, inhibitor oxidative process, and effectively suppress the growth of cataract in rat. Propolis can not be used as raw material, and it must be purified by extraction with solvent. Different solvents may extract different compounds, influencing its activity. The purpose of this research was to determine the difference levels of CAPE in ethanol extract propolis and water extract propolis. This research was a pure experimental research using the post-test only design. The sample of this research was raw propolis taken from bees farming in Gejen RT. 03 RW. 02, Kerjo, Karanganyar. Sampling was performed by a purposive sampling. Sample was extracted with a maserasion method with the solvents of ethanol and water. In each extract propolis was made five samples. The determination of the level of CAPE on propolis was performed by using UV-Vis spectrophotometry with Prussian Blue method. The data of the level of CAPE was analyzed by the statistical test of independent t-test. The results showed that the average of CAPE level in ethanol extract propolis was 12.268±0.658 μg/mL and the average of CAPE level in water extract propolis was 5.564±0.332 μg/mL, with p=0.125 (p>0.05). There was no significant difference between extract ethanol propolis and water extract propolis.

2010 ◽  
Vol 150-151 ◽  
pp. 1063-1067
Author(s):  
Fei Fei Zhu ◽  
Zhi Li Zhong ◽  
Zong Fu Guo

The three composite boards which were made of continuous basalt fiber (CBF) and polypropylene fiber (PP) in different fiber ratios were researched on this paper. The manufacturing forming process included blending, carding, web formation, laminating and compression molding orderly. The tension and bending properties were investigated experimentally, and then dual variance analysis was used to show the significant difference of the mechanical property in the transverse and longitudinal orientation as well the appreciable impact of different fiber ratios to the mechanical property. The results show that the difference of the tension and blending strength in the same direction, among composite boards in different fiber proportions, is about 1~10Mpa; the difference in the same fiber proportion, between transverse and longitudinal, vary within a wide range from 10Mpa to 30Mpa. The results of variance analysis have also proved the conclusion, the difference between transverse and longitudinal is more significant than the difference among different fiber proportions. In the similar study, the significance hadn’t been seen sufficiently, so this paper provides reference to the actual application of the composite board.


2017 ◽  
Vol 13 (10) ◽  
pp. 124 ◽  
Author(s):  
Norhayati Che Hat ◽  
Mohd Fauzi Abdul Hamid ◽  
Shaferul Hafes Sha'ari ◽  
Safawati Basirah Zaid

Implementation of animation as an Arabic language teaching aid is an innovation in creating an atmosphere that can influence student achievement. This study aimed to identify the effectiveness of the use of animation in Arabic language teaching and learning among diploma students at Universiti Sultan Zainal Abidin (UniSZA), Terengganu, Malaysia. A total of 66 diploma students were randomly selected and divided into experimental group (n = 33) and control group (n = 33). The results obtained from the data collected from pre-and post-test for each group were analyzed using t-test in SPSS version 17.0. The results showed a significant difference of (t = 8789, df = 64, p <0.05) between the achievement of the experimental group and the control group in the post test. The difference in mean score of the experimental group and the control group was 33.03. This shows that there is significant improvement in Arabic language according to the groups. The difference prove that the use of animation in learning sessions contribute to the achievement of students in the Arabic language. This study advocate the idea that animation applications can be integrated as part of language teaching aid to positively improve student achievement, classroom learning environment and student motivation. 


2020 ◽  
Vol 5 (3) ◽  
pp. 200
Author(s):  
Andi An-Nisaa Arfin ◽  
Kamaluddin Kamaluddin ◽  
Wa Ode Fatmawati

The purpose of conducting this research is to examine the difference NGain scores between students who learn vocabulary with Blindfold Game and students who learn vocabulary without Blindfold Game at the first year students of SMP Negeri 13 Kendari. The samples of this research are the first grade four (VII-4) and the first grade three (VII-3) which consists of 27 students for each class. This research is conducted in comparison research design that consists of experimental class (VII-4) and controll class (VII-3). The data of this research are collected by giving pre-test and post-test in two classes (VII-4 & VII-3). The result shows that there is an improvement of the students’ vocabulary achievement. Independent samples t-test shows that, there is a significant difference in the Ngain scores for experimental class ( M = 60.08,  SD = 9.36 ) and controll class ( M = 20.41, SD = 14.56 ), t (52) = 11.904, p (0.000) < 0.05. Therefore, it can be concluded that the value of Sig (2 tailed) is lower than the significance α value (0.000 < 0.05). In other words, alternative hypothesis (H1) is accepted and the null hypothesis (H0) is rejected. It means that the Blindfold game can enrich students’ vocabulary achievement for Junior High School Student.


2019 ◽  
Vol 2 (2) ◽  
pp. 189-200
Author(s):  
Yestiani Norita Joni ◽  
Busjra M Nur ◽  
Fitrian Rayasari

The purpose of this study is to know the effectiveness of intradialysis exercise using barbells and Range of Motion (ROM) on the adequacy of hemodialysis in patients with chronic kidney disease in the hemodialysis room of RSIJ Sukapura in 2018. The design of this study uses a design with non-probability pre and post test two groups without control design . The result of the difference in the effectiveness of the adequacy values between the two intervention groups after the intervention was given was the barbell intervention obtained 1,33 with a standard deviation of 0.485, an error standard of 0.114. Whereas in the ROM intervention group 1.67 the standard deviation was 0.485, the standard error was 0.114 and the p-value was 0.047 (> 0.05). Conclusion, there was no significant difference in the value of hemodialysis adequacy between the barbellROM intervention groups after the intervention.   Keywords: Hemodialysis Adequacy, Barbell, Exercise Effectiveness, Intradialysis, Range Of Motion (ROM)


2017 ◽  
Vol 30 (4) ◽  
pp. 439-444 ◽  
Author(s):  
Ester Del Duca ◽  
Francesca Farnetani ◽  
Nathalie De Carvalho ◽  
Ugo Bottoni ◽  
Giovanni Pellacani ◽  
...  

Psoriasis is a chronic inflammatory skin disease affecting 2%–3% of the population. The wide range of drugs currently available for its treatment could be associated, in the long term, with organ toxicity and adverse events, thus, clinical monitoring throughout treatment is required. This investigator-initiated trial (IIT) evaluated the efficacy and the safety of a vitamin B12-containing ointment in comparison with glycerol-petrolatum-based emollient cream used twice a day to treat mild-to-moderate plaque psoriasis for a period over 12 weeks followed by a wash-out observation period of 4 weeks. This study was conducted as a randomized, controlled, single-blind, intra-patient left- to right-side trial comparing the efficacy and safety of vitamin B12-containing ointment (M-treatment) with a glycerol-petrolatum-based emollient cream (C-treatment). The Psoriasis Area Severity Index (PASI) was determined at baseline (T0), at time points T2 (14 days), T4 (4 weeks), T8 (8 weeks), T12 (12 weeks) and 4 weeks after the end of the wash-out period (F1). In total, 24 patients with plaque psoriasis were randomized to receive left- or right-side treatment with B12 ointment. From time point T2 to time point F1, there was a statistically significant difference in PASI reduction between M-treatment side and C-treatment side. At time point T 12, the difference between the mean reductions from baseline PASI scores by 5.92 ± 2.49 (87, 6%) in the M-treatment side versus 1.08 ± 1.02 (23, 1%) C-treatment side was statistically highly significant ( PWex < 0.001). On the contemporary panorama in the treatment of psoriasis, we conclude that vitamin B12 ointment will represent a new concrete therapy option and should be considered in the update of therapeutic algorithm for the treatment of psoriasis


Cosmetics ◽  
2018 ◽  
Vol 5 (3) ◽  
pp. 51 ◽  
Author(s):  
Maria Bastianini ◽  
Caterina Faffa ◽  
Michele Sisani ◽  
Annarita Petracci

Bioactive ingredients from natural sources possess well-known positive effects in cosmetic applications. Among them, phenolic acids have emerged with very interesting potential. Caffeic acid (CAF) is one of the most promising active compounds because it possess antioxidant, anti-inflammatory, antitumoral and anti-wrinkle effects. In order to increase its local bioavailability in topical applications, the vehiculation of caffeic acid can lead to a new raw material of cosmetic interest. For this purpose, clay minerals possess excellent properties, such as low or null toxicity and good biocompatibility. Clays are able to host a wide range of active ingredients in the interlayer region, using a green process known as intercalation reaction. The hosting of cosmetic actives into the layered structure of anionic clays allows the preparation of new materials with enhanced stability towards oxidation and photodegradation, better local bioavailability, and easier workability. In this paper, the successful vehiculation of caffeic acid into anionic clay is presented. The obtained hybrid is very promising for the cosmetic market because of its higher bioavailability and prolonged antioxidant activity.


2021 ◽  
Vol 5 (2) ◽  
pp. 95
Author(s):  
Gunawan Setiawan ◽  
Syamsuramel Syamsuramel ◽  
Silvi Aryanti

This study aims to develop a small game-based basic motion learning model at Elementary School Number 65 Rejang Lebong. The research method used is research and development (R&D) using ten stages from Borg and Gall. The research instruments used were locomotor, non-locomotor tests, and manipulative basic movement skills tests. The treatment in this study was in the form of a basic motion learning model based on small games given for 4 weeks. The subjects in this study were students in grades 4 and 5 of Elementary School Number 65 Rejang Lebong. Subjects in this study were 30 people. The validation results obtained in small-scale trials regarding the quality of the learning model have entered into the validation criteria filled by the validator with a percentage of 63% and the results of large group trials are declared valid with a percentage of 81.25% which means very feasible. Furthermore, the effectiveness test was carried out using the t-test. In the significance test of the difference using the SPSS tool, the mean value = 0.8666 which shows the difference between the pre-test and post-test results, the results of T-count = 13.730, df = 29, and P-Value = 0.000 <0.05, which means that there are There is a significant difference between before and after being treated with the small game-based learning model of throwing basic motion learning. Where the post-test results have positive results with a significant difference compared to the pre-test results. So that the learning model of the basic motion of throwing based on small games can be used in learning physical education and health in elementary schools. The implication of this research is that the basic motion learning model of throwing based on small games can be used as a form of learning the basic motion of throwing in elementary school children.


Author(s):  
Sukma Adelina Ray ◽  
Abdurahman Adisaputera ◽  
Isda Pramuniati

The aims of this study to find out the quality of E-learning based on learning media using Moodle LMS on text of observation. This type of research is development research in the field of education known as Research and Development (R&D). Development research (development research) is research that is used to produce certain products and test the effectiveness of these products (Tegeh and I.M, 2013). The result of this study show that The quality of e-learning based learning media using LMS Moodle which was developed as a learning media on the observation report text material is stated to be a useful and effective contribution in improving the quality of learning outcomes of 10th grade TJA1 Vocational School Telkom Shandy Putra Medan. This is because there is a significant difference in the learning outcomes of the average value of students before using e-learning based learning media (pre-test) ie 57.0 or only about 52% are able to exceed KKM and after using e-based learning media learning using LMS Moodle (post-test) the average value of students increased to 77.0% or can be interpreted as 100% of students able to exceed the KKM. Based on these data the difference is increased by 20% or can be interpreted student learning outcomes increased by 58%.


Jurnal NERS ◽  
2017 ◽  
Vol 9 (1) ◽  
pp. 26 ◽  
Author(s):  
Joko Setyono ◽  
Dwi Adi Nugroho ◽  
Mustofa Mustofa ◽  
Saryono Saryono

Introduction: Obesity prevalence is estimated increases, reached 19.1% of the population aged 15 years and over. This study aimed to determine the differences of the anti- obesity effect of orlistat, an extract of green coffee beans (Coffea canephora robusta), and its combination to the adiponectin levels and lipid profi le. Method: This research was true experimental post -test only with control group design with completely randomized design (CRD). Experimental animals (Rattus novergicus) were divided into 6 group, group 1 ( negative control ), group 2 ( positive control ), group 3 was group of obese rats fed orlistat dose of 15.9 mg/kg, group 4 was the group of obese rats were fed ethanol extract of green coffee beans dose of 400 mg/kg, group 5 was the group of obese rats were given water extract of green coffee beans dose of 400 mg/kg, and group 6 was group of obese rats were fed a combination of orlistat dose of 15.9 mg/kgand ethanol extract of green coffee beans at a dose of 400 mg/kg. Lipid profi les and adiponectin levels were measured with a spectrophotometer at 500nm absorbance. The data were analyzed by one-way ANOVA, and then post hoc Least Significant Difference (LSD) with α = 0.05. Result: Ethanol extract of green coffee is more effi cient in lowering LDL cholesterol, increasing HDL cholesterol, and lowering the total cholesterol levels on HFD diet-induced mice, but there was no difference in lowering triglycerides . The combination of ethanol extract of green coffee with orlistat showedthe increasing of adiponectin levels were highest than the other treatment groups. Discussion: The ethanol extract of green coffee readily diffuses through the digestive tract epithelium. Green coffee contains chlorogenic acid active compounds that can increase the body’s metabolism, increase fatty acid oxidation, reduce levels of triglycerides in the liver, and working to inhibit lipase and amylase pancreaticenzymes. In addition to chlorogenic acid, polyphenol content in coffee is also potentially reduce visceral fat accumulation. Preparations extract by ethanol allows the absorption process is done effi ciently and quickly.Keywords: obesity, orlistat, greencoffee, lipid profi le, adiponectin


Author(s):  
Dang Thi Thu Huong ◽  

The current study determines the effectiveness of using task-based language instructions in teaching writing at a high school in Thai Nguyen province. The participants consist of 92 grade 10 students from Bing Yen high school, Dinh Hoa district. The study employs a mix method research design (MMR) as the plan for the research. The results of the study reveals that the results of writing performance were reported at a low level (M=3.72). The results also confirmed that the intervention worked well for the experimental group. The mean score of the pre-test (the baseline for both groups) was M=3.72. The intervention focused on TBLT instructions. After first five weeks, the means of post-test1 were M=4.96 and M=3.83 for experimental group and control group respectively. There was a significant difference between the mean of pre-test and post-test1 for the experimental group (M=3.72 compared to M=4.96), while the control group showed a little improvement (M=3.72 compared to M=3.83) the difference was not significant. After another five weeks, the difference in the mean scores of the experimental group were far more than the mean scores of the control group, M=5.56 and M=4.45 respectively. By the end of the fifteenth week of the intervention, the mean of post-test 3 of the experimental group reached M=6.41, the mean for control group was M=5.54. The difference of the mean scores in the pre-test and post-test revealed a significant improvement in both groups. However, the experimental group showed a greater improvement, M=6.41 and M=5.54 respectively. It can infer that the uses of TBLT writing instruction improved writing achievement greatly.


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