scholarly journals Hyperuricemia versus lifestyle in men and women of the Russian Federation population

2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Sergej A. Maksimov ◽  
Svetlana A. Shalnova ◽  
Yuliya A. Balanova ◽  
Aleksandr D. Deyev ◽  
Svetlana E. Evstifeyeva ◽  
...  

Objective ― Analyzing gender-related specificities of hyperuricemia associations with lifestyle choices in the Russian Federation (RF) population. Material and Methods ― Cross-sectional survey was performed within the guidelines of the Russian national multicenter study ESSE-RF. The final sample size was 20781 people 25-64 years old. The effect of age, body mass index (BMI), diet, smoking status, and alcohol consumption on the incidence of hyperuricemia was evaluated. The analysis was carried out separately for men and women, using logistic regression. To build a model for predicting hyperuricemia, classification trees were used. Results ― Multidirectional associations of hyperuricemia were revealed both in women (with BMI, age, ‘Smart’ dietary pattern, alcohol consumption) and in men (with BMI, ‘smart’ dietary pattern, alcohol consumption, smoking status). The predictive accuracy of hyperuricemia incidence models was 60.4% in women vs. 65.7% in men. In both gender groups, BMI had the highest contribution to predicting the hyperuricemia incidence, while the next predictors, in terms of significance, differed among men and women. In women, the greatest impact, in decreasing order, was exerted by age, dietary patterns and drinking, whereas in men, by smoking status, dietary patterns and drinking. Conclusion ― In the RF population, there are multiple gender-specific associations of hyperuricemia with lifestyle choices, particularly nutrition, smoking and alcohol consumption.

2018 ◽  
Vol 22 (06) ◽  
pp. 1037-1047 ◽  
Author(s):  
MGM Pinho ◽  
JD Mackenbach ◽  
J-M Oppert ◽  
H Charreire ◽  
H Bárdos ◽  
...  

AbstractObjectiveTo explore the associations of absolute and relative measures of exposure to food retailers with dietary patterns, using simpler and more complex measures.DesignCross-sectional survey.SettingUrban regions in Belgium, France, Hungary, the Netherlands and the UK.ParticipantsEuropean adults (n 4942). Supermarkets and local food shops were classified as ‘food retailers providing healthier options’; fast-food/takeaway restaurants, cafés/bars and convenience/liquor stores as ‘food retailers providing less healthy options’. Simpler exposure measures used were density of healthy and density of less healthy food retailers. More complex exposure measures used were: spatial access (combination of density and proximity) to healthy and less healthy food retailers; density of healthier food retailers relative to all food retailers; and a ratio of spatial access scores to healthier and less healthy food retailers. Outcome measures were a healthy or less healthy dietary pattern derived from a principal component analysis (based on consumption of fruits, vegetables, fish, fast foods, sweets and sweetened beverages).ResultsOnly the highest density of less healthy food retailers was significantly associated with the less healthy dietary pattern (β = −129·6; 95 % CI −224·3, −34·8). None of the other absolute density measures nor any of the relative measures of exposures were associated with dietary patterns.ConclusionsMore complex measures of exposure to food retailers did not produce stronger associations with dietary patterns. We had some indication that absolute and relative measures of exposure assess different aspects of the food environment. However, given the lack of significant findings, this needs to be further explored.


2016 ◽  
Vol 12 (6) ◽  
pp. 711-717 ◽  
Author(s):  
G. A. Muromtseva ◽  
A. D. Deev ◽  
V. V. Konstantinov ◽  
A. A. Shalnova ◽  
S. A. Boytsov

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Sidsel Graff-Iversen ◽  
Stephen Hewitt ◽  
Lisa Forsén ◽  
Liv Grøtvedt ◽  
Inger Ariansen

Abstract Background Studies indicate an effect of smoking toward abdominal obesity, but few assess hip and waist circumferences (HC and WC) independently. The present study aimed to assess the associations of smoking status and volume smoked with HC and WC and their ratio in a population with low prevalence of obesity together with high prevalence of smoking. Methods We used cross-sectional survey data from 11 of a total 19 Norwegian counties examined in 1997–99 including 65,875 men and women aged 39–44 years. Analysis of associations were adjusted for confounding by socioeconomic position, health indicators, and additionally for BMI. Results Compared with never-smokers, when adjusting for confounders and in addition for BMI, mean HC remained lower while mean WC and waist-hip-ratio (WHR) were higher in current smokers. The finding of a lower HC and higher WHR level among smokers was consistent by sex and in strata by levels of education and physical activity, while the finding of higher WC by smoking was less consistent. Among current smokers, BMI-adjusted mean HC decreased whereas WC and WHR increased by volume smoked. Compared with current smokers, former smokers had higher BMI-adjusted HC, lower WHR and among women WC was lower. Conclusions The main finding in this study was the consistent negative associations of smoking with HC. In line with the hypothesis that lower percentage gluteofemoral fat is linked with higher cardiovascular risk, our results suggest that smoking impacts cardiovascular risk through mechanisms that reduce the capacity of fat storage in the lower body region.


2019 ◽  
Vol 15 (5) ◽  
pp. 612-621
Author(s):  
S. A. Shalnova ◽  
M. V. Ezhov ◽  
V. A. Metelskaya ◽  
S. E. Evstifeeva ◽  
V. I. Tarasov ◽  
...  

Experimental and clinical data indicate a significant contribution of lipoprotein(a) (Lp[a]) to the atherogenesis. However, the pathophysiological mechanisms of this relationship are not fully understood.Aim. To investigate the distribution of Lp(a) in the population of the regions participating in the Study “Epidemiology of Cardiovascular Diseases in the Regions of the Russian Federation” (ESSE-RF) and to evaluate its associations with cardiovascular risk factors.Material and methods. Representative samples of the male and female population of 7 regions of the Russian Federation, aged from 25 to 64 years, enrolled in the multi-center cross-sectional epidemiological study were analyzed. A total of 10332 people were examined, of whom 3732 were men (36.0%) and 6600 were women (64.0%), the average age was equal in both sexes.Results. The mean value of Lp(a) reached 22.4 mg/dl (standard deviation 21.3 mg/dl) and significantly differed from the median (11.1 mg/dl; interquartile range from 3.9 to 20.2 mg/dl), forming the right-skewed distribution in both male and female population. Lp(a) levels were statistically significantly correlated with the level of low-density lipoproteins cholesterol (LDL-C), ароВ/аpoAI and total cholesterol. Notably, the odds ratios were growing by quintiles, and increased along with increasing lipid values (p<0.0001). Lp(a) levels were also positively associated with high-sensitivity C-reactive protein (hs-CRP) and negatively correlated with blood concentration of glucose and triglycerides (TG). There were no associations with body mass index, waist circumference and smoking status.Conclusion. According to the ESSE-RF data, there are significant positive associations of Lp(a) with the LDL-C level, the ароВ/аpoAI ratio, total cholesterol, and hs-CRP. Negative associations are established with glucose and TG levels. The future studies should be planned with the notion of the Lp(a)’s right-skewed distribution type. 


2019 ◽  
Vol 64 (9) ◽  
pp. 541-545
Author(s):  
I. N. Gorenko

The aim of the study was to determine the levels of thyroid antibodies and their relationship with thyroid hormones and thyroglobulin in euthyroid men and women, residents of the Arctic zone of the Russian Federation. A total of 208 apparently healthy people were enrolled in this study and classified into two groups depending on gender and level of autoantibodies in the blood. Serum hormones of the pituitary-thyroid system, thyroglobulin and antibodies concentration was measured by enzyme immunoassay. The prevalence of positive antibodies among various examined groups was determined and the characteristics of euthyroid subjects with abnormal thyroid antibodies levels were studied. Circulating positive thyroid antibodies were found in 20% of the surveyed residents of the Arctic zone of the Russian Federation. The median serum antibodies against thyroid peroxidase (AntiTPO) or thyroglobulin (AntiTG) levels and the percentage of people in general population with positive antibodies (i.e. AntiTPO ≥ 50 IU / ml and / or AntiTG ≥ 100 IU / ml) were statistically significant higher in women than in men, p < 0.01. Such thyroid antibodies levels were associated with a higher thyroid gland functional activity in women, which was demonstrated by significantly higher thyroxin level and lower thyroglobulin value in the peripheral blood. Part of women positive for AntiTPO increased with age from 18 to 33% (in groups aged 18-44 and 45-59 years, p = 0.04). The findings of the study reveal correlation between thyroid function test and thyroid antibodies levels, elaborating the clinical importance of thyroid antibodies in clinical examination and follow-up of patients with autoimmune thyroid disorders.


2018 ◽  
Vol 148 (10) ◽  
pp. 1598-1604 ◽  
Author(s):  
Esther Vermeulen ◽  
Anika Knüppel ◽  
Martin J Shipley ◽  
Ingeborg A Brouwer ◽  
Marjolein Visser ◽  
...  

Abstract Background The consumption of unhealthy “Western” dietary patterns has been previously associated with depressive symptoms in different populations. Objective We examined whether high-sugar and high-saturated-fat dietary patterns are associated with depressive symptoms over 5 y in a British cohort of men and women. Methods We used data from the Whitehall II study in 5044 individuals (aged 35–55 y). Diet was assessed at phase 7 (2003–2004) using a validated food-frequency questionnaire. Dietary patterns were derived by using reduced rank regression with sugar, saturated fat, and total fat as response variables. The Center for Epidemiological Studies–Depression (CES-D) scale was used to assess depressive symptoms (CES-D sum score ≥16 and/or use of antidepressant medication) at phase 7 and at phase 9 (2008–2009). We applied logistic regression analyses to test the association between dietary patterns and depressive symptoms. All analyses were stratified by sex. Results In total, 398 cases of recurrent and 295 cases of incident depressive symptoms were observed. We identified 2 dietary patterns: a combined high-sugar and high-saturated-fat (HSHF) and a high-sugar dietary pattern. No association was observed between the dietary patterns and either incidence of or recurrent depressive symptoms in men or women. For example, higher consumption of the HSHF dietary pattern was not associated with recurrent depressive symptoms in men (model 3, quartile 4: OR: 0.67; 95% CI: 0.36, 1.23; P-trend = 0.13) or in women (model 3, quartile 4: OR: 1.26; 95% CI: 0.58, 2.77; P-trend = 0.97). Conclusion Among middle-aged men and women living in the United Kingdom, dietary patterns containing high amounts of sugar and saturated fat are not associated with new onset or recurrence of depressive symptoms.


2021 ◽  
pp. 1-30
Author(s):  
Katherine Yorke ◽  
Kate Northstone ◽  
Louise Jones

Abstract Objective To examine the relationship between a posteriori dietary patterns in early childhood and alcohol consumption in adolescence. Design Data was obtained from the Avon Longitudinal Study of Children and Parents (ALSPAC) prospective cohort study. Dietary information was obtained using food frequency questionnaires at ages 3 and 7 years. The association between dietary patterns, derived using Principal Components Analysis (PCA) and the Alcohol Use Disorders Identification Test (AUDIT) scores (to assess harmful intake) and frequency of alcohol consumption at 17 years were examined. Secondary analysis considered sugar intake as a percentage of total energy intake. Setting Women who gave birth between 1 April 1991 and 31 December 1992 in the Avon area in southwest England were eligible for the ALSPAC cohort study. Participants 14,541 pregnancies were enrolled in ALSPAC during its initial recruitment phase. For this analysis, complete data was available for between 3148 and 3520 participants. Results Adherence to the “healthy” dietary pattern at both 3 and 7 years of age was positively associated with consuming more than one alcoholic drink per week at 17 years, whilst adherence to the ‘traditional’ dietary pattern at both ages was protective of harmful alcohol intake at 17. Sugar intake was not associated with either alcohol outcome after adjustment for ethnicity, maternal level of education, parental social class and maternal AUDIT score. Conclusions For the population studied, changes to diet in early childhood are unlikely to have an impact on harmful alcohol use in adolescence given the lack of consistency across the results.


Author(s):  
Irina Savchyenko ◽  
Vladimir Gorbachev

The results of a survey aimed at identifying common and special features in the career attitudes of young men and women studying at the university of the Ministry of Internal Affairs of the Russian Federation and preparing to become police officers are discussed. The authors come to a number of conclusions that are of value for the organization of the educational process in educational institutions that train future police officers.


2021 ◽  
Vol 27 (1) ◽  
pp. 24-32
Author(s):  
Daniil Vladimirovich Surinov ◽  

Today, cardiovascular diseases are the leading cause of death in the world’s population. It is generally known that disease prevention is the best method for maintaining human health. This article discusses the most common risk factors for CVD among young people, older people, as well as men and women, the prevention of which helps to increase the life expectancy of the population


2021 ◽  
pp. 1-12
Author(s):  
Tolassa W Ushula ◽  
Petra H Lahmann ◽  
Abdullah Mamun ◽  
William YS Wang ◽  
Gail M Williams ◽  
...  

Abstract Objective: Previous studies of sociodemographic and lifestyle correlates of dietary patterns among young adults have primarily focused on physical activity and smoking, with inconclusive results. This study aims to examine the associations between a broader range of lifestyles of young adults and their patterns of food consumption. Design: Cross-sectional. Setting: Brisbane, Australia. Participants: The data set are from a long running birth cohort study which commenced in 1981. Details of dietary intake and sociodemographic and lifestyle factors were from the 21-year follow-up of the Mater-University of Queensland Study of Pregnancy (MUSP) birth cohort. The effective cohort (n 2665, 57 % women) is of young adult offspring. Usual dietary intake was assessed using a Food Frequency Questionnaire (FFQ). Data on sociodemographic and lifestyle variables were obtained from self-reports. Results: Western and prudent dietary patterns were identified for the combined cohort of women and men using principal components analysis. Multivariable linear regression models were used to examine the associations between lifestyle variables and dietary patterns adjusting for potential confounders. Results from multivariable adjusted models showed that physical activity, watching TV and smoking were strongly associated with each dietary pattern; alcohol consumption and BMI showed weaker associations (P < 0·05 for all). Conclusions: Our study describes a clustering of unhealthy lifestyles in young adults. Young adults with unhealthy lifestyles less often adhere to a healthy prudent dietary pattern and more often an unhealthy Western pattern. Dietary preferences are enmeshed in a lifestyle matrix which includes physical activity, sedentary activity, smoking and alcohol consumption of young adults.


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