PREGELATINIZED RICE BRAN FLOUR AS STABILIZER FOR GUAVA NECTAR

Rice bran flour is a byproduct of rice processing and can be used as food. The objective of the current study was to use pregelatinized rice bran flour along with hydrocolloids to stabilize guava nectar, as well as to evaluate the stability of bioactive compounds during a storage period of 180 days. For this purpose, the guava fruits were processed in the form of pulp, following the elaboration of the nectars. Four formulations were prepared: one control (pulp, water, and sugar) and three by the addition of xanthan, guar gum, and pregelatinized rice flour. The sedimentation stability, the content of bioactive compounds, and the physicochemical parameters were evaluated at every 45 days of storage. The formulations with guar and pregelatinized rice bran flour gave better results than the others for all the evaluated parameters, indicating that they could be a good option for stabilization of the guava nectar. Moreover, the rice flour seems to be a cost-effective option and is easy to obtain in contrast to the other commonly used hydrocolloids that are generally used in food industry.

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Implementation Study of Patient-Ready Syringes Containing 25 mg/mL Methotrexate Solution for Use in Treating Ectopic Pregnancy

BioMed Research International ◽

10.1155/2014/689308 ◽

2014 ◽

Vol 2014 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

R. Respaud ◽

A. S. Gaudy ◽

C. Arlicot ◽

J. F. Tournamille ◽

M. C. Viaud-Massuard ◽

...

Keyword(s):

Ectopic Pregnancy ◽

Storage Period ◽

Cost Effective ◽

First Trimester ◽

Storage Conditions ◽

Treatment Delays ◽

Effective Delivery ◽

First Trimester Of Pregnancy ◽

The Stability ◽

Physical And Chemical

Background.Ectopic pregnancy (EP) is a significant cause of morbidity and mortality during the first trimester of pregnancy. Small unruptured tubal pregnancies can be treated medically with a single dose of methotrexate (MTX).Objective.The aim of this study was to evaluate the stability of a 25 mg/mL solution of MTX to devise a secure delivery circuit for the preparation and use of this medication in the management of EP.Method.MTX solutions were packaged in polypropylene syringes, stored over an 84-day period, and protected from light either at +2 to +8°C or at 23°C. We assessed the physical and chemical stability of the solutions at various time points over the storage period. A pharmaceutical delivery circuit was implemented that involved the batch preparation of MTX syringes.Results.We show that 25 mg/mL MTX solutions remain stable over an 84-day period under the storage conditions tested. Standard doses were prepared, ranging from 50 mg to 100 mg. The results of this study suggest that MTX syringes can be prepared in advance by the pharmacy, ready to be dispensed at any time that a diagnosis of EP is made.Conclusion.The high stability of a 25 mg/mL MTX solution in polypropylene syringes makes it possible to implement a flexible and cost-effective delivery circuit for ready-to-use preparations of this drug, providing 24-hour access and preventing treatment delays.

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Effect of storage temperature on the crispness, colour and bioactive compounds of an orange snack obtained by freeze-drying

British Food Journal ◽

10.1108/bfj-11-2020-1061 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Marilú Andrea Silva-Espinoza ◽

María del Mar Camacho ◽

Nuria Martínez-Navarrete

Keyword(s):

Vitamin C ◽

Water Content ◽

Bioactive Compounds ◽

Storage Temperature ◽

Storage Period ◽

Point Of View ◽

Total Phenolic ◽

Content Type ◽

Freeze Dried ◽

The Stability

PurposeA healthy and easy-to-use orange snack obtained from the freeze-dried orange pulp puree is proposed. Once the commercial packaging of the snack has been opened, the effect of conventional home storage temperature on its physicochemical properties and on the content of bioactive compounds has been studied. This research aims to recommend the consumer, and therefore the manufacturer, the best conditions for home storage of this product, keeping its nutritional quality and antioxidant capacity, as well as maintaining its colour and crispness.Design/methodology/approachThe water content, water activity, hygroscopicity, crispness, colour, vitamin C, β-carotene, total phenolic compounds and antioxidant activity were characterised both when the orange snack was newly obtained and after one, two and six months of storage inside zipper bags, at 4 and 20 ºC.FindingsThe results indicated that, in these conditions, the orange snack increased its water content, causing a loss in both its porosity and its characteristic crispness. Nevertheless, the bioactive compounds remained stable throughout the storage period, with the exception of β-carotene, the content of which decreased markedly when the orange snack was stored at 20 ºC.Originality/valueFew studies have evaluated the stability of food products during home storage. The findings showed that the maximum storage time to ensure a proper texture of the orange snack studied is between two and six months, both at 4 and 20 ºC. However, from the point of view of the conservation of both vitamin C and, especially, of β-carotene, it is recommended that this product be stored in refrigeration.

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Natural Bioactive Compound Loaded Eggshell Membrane from Waste Food Industry: Preparation and Characterization

Current Nutraceuticals ◽

10.2174/2665978601999200727103101 ◽

2020 ◽

Vol 01 ◽

Author(s):

Merve Deniz Köse ◽

Oguz Bayraktar

Keyword(s):

Bioactive Compounds ◽

Vascular Graft ◽

Food Industry ◽

Bioactive Compound ◽

Eggshell Membrane ◽

Characterization Methods ◽

Eggshell Membranes ◽

The Stability ◽

Adsorptive Properties ◽

Waste Food

Objective: Eggshell membrane (ESM), the protein and collagen-rich membrane between the eggshell and egg white, has usually been regarded as waste and overlooked. However, its potential is now being highlighted in many industrial and technological applications. In the literature natural bioactive compounds (NBCs) have been used together with various proteins. Methods: Preparation and characterization methods of the eggshell and eggshell membrane is summarised. Results: Various studies showed how to utilize eggshell membranes as an adsorbent, scaffold, wound dressing, and vascular graft. Due to the chemical composition of the eggshell membrane, its superior binding and adsorptive properties increase the stability of the bioactive compounds. Conclusion: This review focuses on the potential utilization of eggshell membranes as functional food and nutraceutical.

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Predicting Postpartum Depressive Symptoms from Pregnancy Biopsychosocial Factors: A Longitudinal Investigation Using Structural Equation Modeling

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17228445 ◽

2020 ◽

Vol 17 (22) ◽

pp. 8445

Author(s):

Verónica Martínez-Borba ◽

Carlos Suso-Ribera ◽

Jorge Osma ◽

Laura Andreu-Pejó

Keyword(s):

Structural Equation Modeling ◽

Negative Affect ◽

Structural Equation ◽

Cost Effective ◽

Equation Modeling ◽

Use Of Technology ◽

Effective Option ◽

Biopsychosocial Perspective ◽

The Stability ◽

Affective Ambivalence

The prediction of postpartum depression (PPD) should be conceptualized from a biopsychosocial perspective. This study aims at exploring the longitudinal contribution of a set of biopsychosocial factors for PPD in perinatal women. A longitudinal study was conducted, assessment was made with a website and included biopsychosocial factors that were measured during pregnancy (n = 266, weeks 16–36), including age, affective ambivalence, personality characteristics, social support and depression. Depression was measured again at postpartum (n = 101, weeks 2–4). The analyses included bivariate associations and structural equation modeling (SEM). Age, affective ambivalence, neuroticism, positive, and negative affect at pregnancy were associated with concurrent depression during pregnancy (all p < 0.01). Age, affective ambivalence, positive affect, and depression at pregnancy correlated with PPD (all p < 0.05). Affective ambivalence (β = 1.97; p = 0.003) and positive (β = −0.29; p < 0.001) and negative affect (β = 0.22; p = 0.024) at pregnancy remained significant predictors of concurrent depression in the SEM, whereas only age (β = 0.27; p = 0.010) and depression (β = 0.37; p = 0.002) at pregnancy predicted PPD. Biopsychosocial factors are clearly associated with concurrent depression at pregnancy, but the stability of depression across time limits the prospective contribution of biopsychosocial factors. Depression should be screened early during pregnancy, as this is likely to persist after birth. The use of technology, as in the present investigation, might be a cost-effective option for this purpose.

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Colorimetric parameters as a stability indicative of banana alcoholic extract submitted to storage

Research Society and Development ◽

10.33448/rsd-v9i9.8227 ◽

2020 ◽

Vol 9 (9) ◽

pp. e884998227

Author(s):

Josef Gastl Filho ◽

Millena Almeida Resende ◽

Flávio Caldeira Silva

Keyword(s):

Food Industry ◽

Room Temperature ◽

Storage Time ◽

Storage Period ◽

Raw Material ◽

Banana Peel ◽

Alcoholic Extract ◽

The Stability ◽

Plot Design

Studying the stability of the raw material as a function of the storage time is fundamental to establish the characteristics performance and to determine the period that it should be stored. The objective of the present study was to evaluate the stability of the alcoholic extract for 28 days of storage. It was performed in a completely randomized and split-plot design (3x5) with 3 repetitions and using the following formulation: 500 g of banana components (peel, pulp or peel plus pulp), 1000 mL of cereal alcohol 96 ºGL and maceration process for fifteen days. Filtered alcoholic extracts were stored in a dark place at room temperature for analysis of colorimetric parameters Luminosity, hue, chroma, chromaticity a* and chromaticity b*. Results showed that storage period for 28 days significantly affected stability, promoting notable reduction in Luminosity, hue, chromaticity b* and chroma and also increased the chromaticity value chromaticity a*. It was observed that the banana pulp alcoholic extract showed the highest values for Luminosity and hue, and the banana peel alcoholic extract stood out in relation to the chromaticity chroma, chromaticity a* and chromaticity b*. The information obtained through colorimetric parameters can be used by the food industry to establish procedures that mitigate the effects of the storage period in the raw material, since the characteristics inherent to the raw material are significantly changed over time and result in changes in the quality of the final product.

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Insights into Potent Therapeutical Antileukemic Agent L-glutaminase Enzyme Under Solid-state Fermentation: A Review

Current Drug Metabolism ◽

10.2174/1389200221666200421122147 ◽

2020 ◽

Vol 21 (3) ◽

pp. 211-220 ◽

Cited By ~ 1

Author(s):

Chandrasai Potla Durthi ◽

Madhuri Pola ◽

Satish Babu Rajulapati ◽

Anand Kishore Kola

Keyword(s):

Solid State ◽

Solid State Fermentation ◽

Food Industry ◽

Energy Requirement ◽

Production Studies ◽

Wide Range ◽

Hybridoma Technology ◽

Bacteria And Fungi ◽

The Stability ◽

Glutaminase Activity

Aim & objective: To review the applications and production studies of reported antileukemic drug L-glutaminase under Solid-state Fermentation (SSF). Overview: An amidohydrolase that gained economic importance because of its wide range of applications in the pharmaceutical industry, as well as the food industry, is L-glutaminase. The medical applications utilized it as an anti-tumor agent as well as an antiretroviral agent. L-glutaminase is employed in the food industry as an acrylamide degradation agent, as a flavor enhancer and for the synthesis of theanine. Another application includes its use in hybridoma technology as a biosensing agent. Because of its diverse applications, scientists are now focusing on enhancing the production and optimization of L-glutaminase from various sources by both Solid-state Fermentation (SSF) and submerged fermentation studies. Of both types of fermentation processes, SSF has gained importance because of its minimal cost and energy requirement. L-glutaminase can be produced by SSF from both bacteria and fungi. Single-factor studies, as well as multi-level optimization studies, were employed to enhance L-glutaminase production. It was concluded that L-glutaminase activity achieved by SSF was 1690 U/g using wheat bran and Bengal gram husk by applying feed-forward artificial neural network and genetic algorithm. The highest L-glutaminase activity achieved under SSF was 3300 U/gds from Bacillus sp., by mixture design. Purification and kinetics studies were also reported to find the molecular weight as well as the stability of L-glutaminase. Conclusion: The current review is focused on the production of L-glutaminase by SSF from both bacteria and fungi. It was concluded from reported literature that optimization studies enhanced L-glutaminase production. Researchers have also confirmed antileukemic and anti-tumor properties of the purified L-glutaminase on various cell lines.

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Flavones and Their Analogues as Bioactive Compounds – An Overview

Mini-Reviews in Organic Chemistry ◽

10.2174/1570193x15666180418154510 ◽

2019 ◽

Vol 16 (4) ◽

pp. 377-391 ◽

Cited By ~ 1

Author(s):

B.S. Jayashree ◽

H. Venkatachalam ◽

Sanchari Basu Mallik

Keyword(s):

Biological Activity ◽

Free Radical ◽

Bioactive Compounds ◽

Antioxidant Properties ◽

Radical Scavenging ◽

Cost Effective ◽

Free Radical Scavenging ◽

Polyphenolic Compounds ◽

Pharmacological Activities ◽

Poor Solubility

Flavonoids constitute a large group of polyphenolic compounds that are known to have antioxidant properties, through their free radical scavenging abilities. They possess a chromone (γ- benzopyrone) moiety, responsible for eliciting many pharmacological activities. Even though, natural flavonoids are highly potent, owing to their poor solubility, they are less used. Therefore, attempts have been made to improve their stability, solubility, efficacy and kinetics by introducing various substituents on the flavone ring. For nearly the last two decades, flavones were synthesized in our laboratory by simple, convenient and cost-effective methods, with the knowledge of both synthetic and semi-synthetic chemistry. In this direction, it was considered worthwhile to present an overview on the synthesized flavonoids. This review creates a platform for highlighting various modifications done on the flavone system along with their biological activity.

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Melatonin Treatment to Pomegranate Trees Enhances Fruit Bioactive Compounds and Quality Traits at Harvest and during Postharvest Storage

Antioxidants ◽

10.3390/antiox10060820 ◽

2021 ◽

Vol 10 (6) ◽

pp. 820

Author(s):

José M. Lorente-Mento ◽

Fabián Guillén ◽

Salvador Castillo ◽

Domingo Martínez-Romero ◽

Juan M. Valverde ◽

...

Keyword(s):

Antioxidant Activity ◽

Bioactive Compounds ◽

Fruit Quality ◽

Storage Period ◽

Soluble Solids ◽

First Year ◽

Quality Traits ◽

Postharvest Storage ◽

Melatonin Treatment ◽

Total Soluble Solids

The effect of melatonin pomegranate tree treatments on fruit quality and bioactive compounds with antioxidant activity at harvest and during storage at 10 °C for 60 days was assayed in two consecutive years, 2019 and 2020. In the first year, trees were treated with 0.1, 0.3 and 0.5 mM of melatonin along the developmental fruit growth cycle, and results showed that bioactive compounds (total phenolics and total and individual anthocyanins) and antioxidant activity at harvest were higher in fruits from melatonin-treated trees than in controls. Other fruit quality parameters, such as firmness, total soluble solids and aril red colour, were also increased as a consequence of melatonin treatment. In fruit from control tress, firmness and acidity levels decreased during storage, while increases occurred on total soluble solids, leading to fruit quality reductions. These changes were delayed, and even maintenance of total acidity was observed, in fruit from melatonin-treated trees with respect to controls, resulting in a fruit shelf-life increase. Moreover, concentration of phenolics and anthocyanins and antioxidant activity were maintained at higher levels in treated than in control fruits during the whole storage period. In general, all the mentioned effects were found at the highest level with the 0.1 mM melatonin dose, and then it was selected for repeating the experiment in the second year and results of the first year were confirmed. Thus, 0.1 mM melatonin treatment could be a useful tool to enhance aril content on bioactive compounds with antioxidant activity and health beneficial effects and to improve quality traits of pomegranate fruit, at harvest and during postharvest storage.

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Anthocyanins Recovered from Agri-Food By-Products Using Innovative Processes: Trends, Challenges, and Perspectives for Their Application in Food Systems

Molecules ◽

10.3390/molecules26092632 ◽

2021 ◽

Vol 26 (9) ◽

pp. 2632

Author(s):

Henrique Silvano Arruda ◽

Eric Keven Silva ◽

Nayara Macêdo Peixoto Araujo ◽

Gustavo Araujo Pereira ◽

Glaucia Maria Pastore ◽

...

Keyword(s):

Food Systems ◽

Food Industry ◽

Biological Properties ◽

Extraction Techniques ◽

Naturally Occurring ◽

Current Review ◽

Natural Colorants ◽

Conventional Extraction ◽

The Stability ◽

By Products

Anthocyanins are naturally occurring phytochemicals that have attracted growing interest from consumers and the food industry due to their multiple biological properties and technological applications. Nevertheless, conventional extraction techniques based on thermal technologies can compromise both the recovery and stability of anthocyanins, reducing their global yield and/or limiting their application in food systems. The current review provides an overview of the main innovative processes (e.g., pulsed electric field, microwave, and ultrasound) used to recover anthocyanins from agri-food waste/by-products and the mechanisms involved in anthocyanin extraction and their impacts on the stability of these compounds. Moreover, trends and perspectives of anthocyanins’ applications in food systems, such as antioxidants, natural colorants, preservatives, and active and smart packaging components, are addressed. Challenges behind anthocyanin implementation in food systems are displayed and potential solutions to overcome these drawbacks are proposed.

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Electrochemical Biosensors in Food Safety: Challenges and Perspectives

Molecules ◽

10.3390/molecules26102940 ◽

2021 ◽

Vol 26 (10) ◽

pp. 2940

Author(s):

Antonella Curulli

Keyword(s):

Food Industry ◽

Electrochemical Sensors ◽

Cost Effective ◽

Electrochemical Biosensors ◽

Food Chains ◽

Sensing Systems ◽

Highly Sensitive ◽

Skilled Personnel ◽

Recent Developments ◽

Key Issues

Safety and quality are key issues for the food industry. Consequently, there is growing demand to preserve the food chain and products against substances toxic, harmful to human health, such as contaminants, allergens, toxins, or pathogens. For this reason, it is mandatory to develop highly sensitive, reliable, rapid, and cost-effective sensing systems/devices, such as electrochemical sensors/biosensors. Generally, conventional techniques are limited by long analyses, expensive and complex procedures, and skilled personnel. Therefore, developing performant electrochemical biosensors can significantly support the screening of food chains and products. Here, we report some of the recent developments in this area and analyze the contributions produced by electrochemical biosensors in food screening and their challenges.

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