scholarly journals PLANT-BASED REMEDIES FOR THE MANAGEMENT OF DIABETES

2017 ◽  
Vol 8 ◽  
pp. 34 ◽  
Author(s):  
Sumiksha Gupta ◽  
M.C. Sidhu ◽  
A.S. Ahluwalia

<p>The knowledge related to medicinal plants have been described in Indian Ayurveda System and survived till today through the prevalent socio-cultural practices. Present study is an attempt to document anti-diabetic plants from Una district of Himachal Pradesh. A thorough survey was conducted from 500 respondents using a semi-structured questionnaire and informal discussions. A total of 84 anti-diabetic plant species have been recorded. These plants include wild (32) or cultivated (41) species. Fabaceae was the dominant family with 10 species. The phytoremedies were prepared using different plant parts or sometimes even the whole plant or in combination with other species. There are only few reports on anti-diabetic use of some wild species from the study area. Further studies of bioactive compounds in these species can depict their hypoglycemic potential. Present study has suggested a strong link between traditional herbal medicines, their documentation and proper chemical characterization to harness their therapeutic potential to the maximum.  </p><p><strong>KEY WORDS: </strong>Diabetes, bioactive compounds, traditional medicines, phytoremedies, angiosperms, Una, Himachal Pradesh</p>

2019 ◽  
Vol 12 (04) ◽  
pp. 1923-1935
Author(s):  
Ananta Swargiary ◽  
Mritunjoy Kumar Roy ◽  
Manita Daimari

Ethnobotanical knowledge has been the backbone of rural healthcare since ancient times. Many diseases including helminthiasis are cured by traditional medicine in many parts of the world. The present study aims at exploring the ethnobotanicals used as anthelmintic medicines by the tribal communities of Chirang district of Assam. The present study was conducted in different villages under Chirang district of Assam, India. A face-to-face interview was carried out during survey work along with readymade questionnaire. In our survey work, 20 neighbouring villages were taken as a single cluster and one sample informant was collected. Information regarding the plant and plant parts used, methodology of use as well as informant demography such as age, sex, education was also collected. A total of 20 villages were surveyed and information was gathered from 27 informants, 23 kaviraja and 4 elderly people, 15 male and 12 female. The information collected revealed 43 medicinal plants belonging to 27 families. Lamiaceae was found to be most common family followed by Cucurbitaceae, Fabaceae, Zutaceae and Zingiberaceae. The most highly cited plants were Ananas comosus, Andrographis paniculata, Asparagus racemosus, Alstonia scholaris and Leucas aspera. Leaves, fruits and tubers were found to be the most commonly used plant parts. Except few, most of the herbal medicines were prepared as raw materials and are consumed orally. Documentation of important ethnomedicinal information from the remote areas of Assam will help scientific investigators to look into its scientific aspect leading to the development of new medicines against helminthiasis and many other diseases.


Author(s):  
Priyanka Goyal ◽  
Rohit Chhabra ◽  
Lavanya Vij

Murraya koenigii, also widely known as curry leaves and curry patta, is a noticeably significant plant recognized all around the world for its tremendous therapeutic, medicinal worth and characteristic aromatic properties. It is one of the major export commodities originated from east and southern part of India bringing good foreign revenue. This review article is designed to assess and compile all the currently available literature on ethnobotanical aspects and phytochemical, pharmacological potentials of M. koenigii. Morphologically, it is a semi deciduous small shrub or aromatic shrub having slender but strong woody stem with branches covered with grey bark. The whole plant of M. koenigii viz., as stem, leaf, fruits, root and seeds have been accounted to have anti-oxidant, anti-fungal, anti-candidal, anti-bacterial, anti-hypersensitive and various biological properties. It is also additionally used in hormonal therapy in traditional medicines as a dysenteric, blood purifier, diuretic, febrifuge, hair tonic, anti-inflammatory, analgesic, antipyretic and anti-diarrheal. M. koenigii oil is said to have massive impact in the pharmaceuticals and in aromatherapy enterprises as a powerful ingredient. Many researchers have worked on all parts of M. koenigii, from roots, stem, leaves up its bark. This review is an attempt to summarize all the diverse literature available so as to compile a reliable review article on M. koenigii providing detailed information on therapeutic potential, health benefits and pharmacological applications of the plant.


2021 ◽  
Vol 25 (7) ◽  
pp. 183-190
Author(s):  
Mansi Srivastva ◽  
Gargi Singh ◽  
Laxmi Parwani ◽  
Jaspreet Singh

Plant-derived medicines are long being used for the prevention and treatment of various human ailments. For the last few decades, plants are widely being explored for their active ingredients due to their immense potential in the treatment of critical illnesses. Thus, in recent years, exponential growth can be seen in the field of herbal medicines. Medicinal plants are a unique source of valuable phytochemicals. Their use in different medicine systems is gradually increasing due to their cost-effectiveness, easy availability and natural origin with fewer or no side effects. Acacia nilotica (L.) is a member of the family Fabaceae, commonly found in tropical and sub-tropical regions and the plant is widely known for its enormous medicinal values. Every plant part of A. nilotica is a source of many bioactive important secondary metabolites that are widely useful for the cure of various human diseases and the development of new drugs. An exhaustive literature survey revealed that tannins, flavonoids, alkaloids, polyphenols, fatty acids and carbohydrates are present as major classes of phytochemicals in different plant parts of A. nilotica. These phytochemicals exhibit significant antioxidant, anti-inflammatory, antibacterial, antifungal, antidiarrheal, antihypertensive, antispasmodic, anthelmintic, antiplatelet aggregation, anticancer and antiviral activities. The present review is aimed to organize the comprehensive information available on phytochemical composition and medicinal properties of different plant parts of A. nilotica viz. leaves, bark, flowers, seeds, pods, gum and roots. The study is useful to explore the therapeutic potential of different plant parts of A. nilotica which will further help in the development of new promising, safe, cost-effective drugs with a high therapeutic index from the different parts of the Acacia plant.


Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 636
Author(s):  
Fatima Ez-Zahra Amrati ◽  
Mohammed Bourhia ◽  
Hamza Saghrouchni ◽  
Meryem Slighoua ◽  
Andriy Grafov ◽  
...  

Caralluma europaea (Guss.) N.E.Br.: (C. europaea) is a wild medicinal plant belonging to the family Apocynaceae. It is commonly used in traditional medicines for treating several diseases. The present work aims to evaluate the anti-inflammatory, antibacterial, and antifungal potentials of C. europaea fractions including hydro ethanol (ET CE), n-butanol (But CE), and polyphenol (Poly CE). The chemical composition of hydroethanol, n-butanol, and polyphenol-rich fractions from C. europaea were determined using GC-MS after silylation. The anti-inflammatory effect of hydroethanol, n-butanol, and polyphenol-rich fractions was studied by carrageenan-induced paw edema. Antibacterial and antifungal activities of hydroethanol, n-butanol, and polyphenol-rich fractions against Gram-positive bacteria, Gram-negative bacteria, and yeasts were assessed using the disc diffusion and micro-dilution assays. The findings of the chemical characterization affirmed the presence of interesting bioactive compounds in C. europaea fractions. The polyphenol-rich fraction was the best inhibitor of edema by75.68% after 6 h of treatment. The hydroethanol fraction was the most active against both bacteria and yeasts. This study contributes to society as it provides potential bioactive compounds in C. europaea extract, which may help in fighting nosocomial antibiotic-resistant microbes.


2021 ◽  
Vol 11 (2) ◽  
pp. 108-112
Author(s):  
Ved Prakash ◽  
Anand Sagar

Plant products have served as a major source of useful drugs for centuries and about half of the pharmaceuticals in use today are derived from these natural products. The efficacy and safety of herbal medicines have attracted the attention of scientists towards medicinal plants research. The present study was designed to investigate the whole plant extracts of Achyranthes aspera L. for their anti-enzyme (α-amylae and urease) activity. All the extracts of A. aspera were reported to show good alpha-amylase and urease inhibitory activity of greater than 50% in all the solvents used at a concentration of 1 mg/mL. α- amylase inhibition ranged from 17.66±0.10-69.90±0.50% whereas urease inhibitory activity ranged from 18.60±0.50 to 79.90±0.50% suggesting a strong α- amylase and urease inhibitory effects of this plant. Thus the study provided scientific evidence to the traditional uses of this plant in the treatment of obesity, diabetes, ulcers, kidney stones intestinal infections etc. Therefore, the whole plant extracts of A. aspera can be selected for further investigation to find their therapeutic potential. Keywords: Achyranthes aspera, plant extracts, α-Amylase, Urease


2021 ◽  
Vol 12 (2) ◽  
pp. 1521-1528
Author(s):  
Alfred Maroyi

Ehretia cymosa Thonn. is a deciduous medium-sized to large tree which occurs naturally from Sierra Leone in West Africa to Eritrea and Kenya in East Africa, and Zimbabwe in southern Africa. This study aims to provide a comprehensive review of medicinal uses, phytochemistry and biological activities of E. cymosa. This review examines the existing literature on the medicinal uses, phytochemistry and biological activities of E. cymosa. This study revealed that the bark, leaf juice, leaves, roots, seeds, stems, twigs and whole plant parts of E. cymosa are mainly used as aphrodisiac, laxative and ethnoveterinary medicines and as traditional medicines for gastro-intestinal problems, wounds, malaria, fever, typhoid, convulsions, epilepsy, toothache and respiratory infections. Phytochemical research revealed that the species is characterized by alkaloids, anthraquinones, essential oils, fatty acids, flavonoids, glycosides, phenolics, proanthocyanidins, pseudotannins, reducing sugars, saponins, steroids, tannins and terpenes. Ethnopharmacological research revealed that the extracts of E. cymosa and phytochemical compounds isolated from the species showed antibacterial, antidiabetic, antihyperglycaemic and antioxidant activities. Ehretia cymosa  should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.


2020 ◽  
Vol 13 (2) ◽  
pp. 242-249
Author(s):  
Tri Cahyanto ◽  
Afriansyah Fadillah ◽  
Risda Arba Ulfa ◽  
Rizal Maulana Hasby ◽  
Ida Kinasih

AbstrakPemanfaatan pucuk daun mangga (Mangifera indica L.) oleh masyarakat menjadi lalapan dan dipercaya berkhasiat sebagai obat tradisional. Hal ini merupakan suatu proses kearifan lokal berdasarkan pengalaman empiris orang-orang terdahulu yang kemudian dijadikan kajian studi ilmiah, yaitu etnobotani. Kajian studi etnobotani termasuk pemanfaatan pucuk daun mangga sebagai lalapan masih jarang dilakukan. Penelitian ini bertujuan untuk mengetahui senyawa bioaktif termasuk mangiferin yang terkandung dalam lima kultivar mangga. Sampel kultivar mangga yang digunakan dalam penelitian antara lain Manalagi, Arum manis, Cengkir, Gedong apel dan Golek. Metode penelitian yang digunakan yaitu skrining fitokimia dan pengukuran kadar senyawa mangiferin dengan HPLC. Hasil penelitian menunjukkan sampel positif mengandung senyawa bioaktif alkaloid, flavonoid, saponin dan tanin. Kadar senyawa mangiferin paling tinggi secara berurutan terdapat pada kultivar Arum manis (20,83%), Manalagi (20,56%), Gedong apel (18,54%), Cengkir (15,10%), dan Golek (5,05%). Kultivar mangga Arum manis memiliki kadar mangiferin paling tinggi, untuk selanjutnya dapat dikaji pemanfaatannya sebagai obat herbal tradisional. Abstract Utilization young leaf of mango (Mangifera indica L.) by the community as lalapan and it is believed to be efficacious as traditional medicines. This process through of local wisdom based on empirical experience of conservative people used as a scientific study, namely ethnobotany. Ethnobotany studies include the use of mango leaf shoots as fresh vegetables are still rarely performed.This study aims to determine bioactive compounds including mangiferin contained in five cultivars of mango. Mango cultivar samples used in this study include Manalagi, Arum manis, Cengkir, Gedong apel and Golek. The research method used was phytochemical screening and measurement of mangiferin compounds by HPLC. The results showed a positive sample containing bioactive compounds, alkaloids, flavonoids, saponins and tannins. The highest levels of mangiferin compounds were found in Arum manis (20.83%), Manalagi (20.56%), Gedong apel (18.54%), Cengkir (15.10%) and Golek (5.05%). Arum manis cultivars has highest value of mangiferin levels, which can be explored for their use as traditional herbal medicines.


2021 ◽  
Vol 23 (1) ◽  
pp. 161-194
Author(s):  
C.J. Ugwah-Oguejiofor ◽  
I.M. Adebisi

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak was first reported in Wuhan, a city in Hubei Province of China in December, 2019 and is known to be responsible for the novel coronavirus disease (COVID-19). COVID-19 was declared a pandemic in March, 2020 and since then, it has caused a number of deaths in over 200 countries around the world. Extensive researches have continued in the search of effective vaccines or drug compounds against SARS-CoV-2 and a total of 64 vaccines are currently in clinical trials with 12 currently approved for use by different regulatory bodies, depending on the country. Since the outbreak of SARS-CoV-2, many countries have utilised traditional herbal medicines alongside conventional drugs for the treatment of infected patients. In this review, traditional medicines used to prevent or treat SARS-CoV-2 infection are listed along with the plant parts as used by the traditional healers. Additionally, the possible mechanisms responsible for this preventive or therapeutic outcome are also identified and listed. Our literature search was conducted using Google Scholar, PubMed, Scopus and WHO website. Unpublished reports such asdissertations and theses are not included. Plant parts including roots, leaves, flowers, seeds and so on have been used in the treatment of COVID-19. These traditional medicinal herbs may exert their anti-COVID-19 activity by direct inhibition of the virus replication or entry. Some may act by blocking the ACE-2 receptor, SARS-CoV helicase, Type II Transmembrane Serine Protease (TMPRSS2) and which are required by SARS-CoV-2 in order to infect human cells. Others act by inhibiting the SARSCoV-2 life-cycle related proteins, namely chymotrypsin-like cysteine protease (3CL-pro) and Papain-like protease (PL-pro). Medicinal plants are promising alternative medicines for the treatment or prevention of SARS-CoV-2 infection. Further researches, are needed to decipher their active components and structures which may suggest clues for the development of drugs against this novel coronavirus. Keywords: Severe Acute Respiratory Syndrome (SARS-CoV-2), COVID-19, medicinal plants, plant parts, mechanism of action, pandemic,


Author(s):  
O. P. Choko ◽  
A. A. Aiyeloja ◽  
A. T. Oladele ◽  
J. N. Onwuteaka

Objective: This study was aimed at conducting a pilot survey of the ethno-medicinal plants in Finima Nature Park (FNP), Bonny, Nigeria, to elicit common medicinal plants and their uses.  Method: A set of structured questionnaire was used to obtain information from three key informants (Traditional Medicine Practitioners-TMPs) and 62 household heads on the local medicinal utilization of plants in FNP. Plant utilization and preferences, perceived conservation status and use values were documented. Results: Eighty-three (83) plant species belonging to 45 Botanical families were frequently collected from FNP for local medicinal purposes. Rubiaceae was the most abundant (8%) plant family while the plant forms showed trees (46%), herbs (23%), shrubs (21%) and ferns (3%). Plant parts used for local medicine included leaves (44%), stem/barks (21%), roots (16%), whole plant (5%), fruits (5%), seeds (6%), tubers (2%) and flowers (1%). Infectious diseases were the most treated (30%), urogenital and endocrine diseases - such as thyroid (15%) and abdominal diseases (11%). Oral (62%) and dermal (30%) constitutes the main modes of administration. Rauvolfia vomitoria Afzel. had the highest use value (3.5 - 4) while Ocimum gratissimum Linn., Vernonia amygdalina Delile and Alchornea cordifolia Schumach. & Thonn had the least (1). Perceived conservation status of medicinal plants by respondents revealed scarce (9%), threatened (31%) and abundance (60%). Conclusion: Finima Nature Park (FNP) is a repository of medicinal genetic resource and as such, its conservation should be upheld.


2016 ◽  
Vol 5 (12) ◽  
pp. 1475
Author(s):  
Ram Chand ◽  
Rupinder Kaur ◽  
Amandeep Kaur ◽  
Viney Kumar ◽  
C. Nirmala ◽  
...  

The present study was conducted to explore ethnobotanical diversity and importance of local plants harnessing for medicinal purposes by the local people of Una and Hamirpur district which lies at Shivalik hills or outer Himalayas in Himachal Pradesh, India. We recorded total 159 plant species of 138 genera belonging to 68 families which were used to cure more than 33 different types of ailments. Across family-wise distribution, most important useful plants were recorded from ten families: Asteraceae, Euphorbaceae, Fabaceae, Acanthaceae, Ceaselpiniaceae, Moraceae, Solanaceae followed by Anonaceae, Convolvulaceae and Liliaceae. Therefore, these families accounted 43.7% plants of the total and exhibited most acclamatized plants within local environmental conditions. Further, fifty percent of the total recorded plants revealed as herbs contributed the major proportion followed by trees (29%), shrubs (11%), climber (9%), creeper and khumb (<1% each). It was observed that most utilized plant parts were leaves recorded from 55 plant species to cure different ailments followed by other components viz: whole plant (43), bark and seed (34 species each), root and fruits (32 each), flower (18) and other remaining were stem shoot, bulb, rhizome and tubers, respectively. People living to the adjoining area of the forests have the direct influence to utilize those local plants for different ailments; therefore, they have good practices and vast information of traditional knowledge. Thus, aim of the present study was to collect information about ethno-medicinal plants which were not clearly documented earlier in the literature as well as to investigate the plant-human interactions to understand the socio-ecological relationships.


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