scholarly journals ACETOSAL, BUAH MENGKUDU (MORINDA CITRIFOLIA L.) DAN WAKTU PERDARAHAN

2018 ◽  
Vol 18 (2) ◽  
pp. 97
Author(s):  
I Wayan Putu Sutirta Yasa ◽  
Ketut Widyani Astuti ◽  
I Gusti Made Aman
Keyword(s):  
Bleeding Time ◽  
Ethanol Extract ◽  
Morinda Citrifolia ◽  
Control Group ◽  
Fruit Extract ◽  
Control Group Design ◽  
The Third ◽  
Prolonged Bleeding Time ◽  
Study Results ◽  
Post Test

Research regardless the effect of noni fruit for increasing bleeding time have already been carried out widely. The similar activity ofnoni fruit extract and acetosal can be concerned that the fruit extract has a potential activity for prolonged bleeding time. This study aimsto know the present of prolonged of bleeding time as a results of intake of combination of noni fruit extract with acetosal on mice. Thisresearch was carried out at Unit Binatang Percobaan, Departemen Farmakologi Universitas Udayana. This is an experimental study withpre and post-test control group design. Subject was compromised of 3 groups of mice and each group contain of 7 mice. The first groupwas treated with a dose of 40 mg/kg bw acetosal, the second group treated with a dose of 100 mg/kg bw ethanol noni fruit extract, andthe third group treated with combination of 40 mg/kg bw acetosal and 100 mg/kg bw ethanol extract of noni fruit. All groups werefed once per day for a week. Bleeding time was determined on the basis of tail bleeding method. This study results that the first groupexperience bleeding time increased from 61.42±9.43 second to 160.71±19.77 second. Increase bleeding time of the second group is from59.14±7.12 to 138.14±59.91 second. For the third group, the bleeding time increases from 65.00±7.91 to 213.00±20.92 second.One Way ANOVA analysis indicates that there is a significant different among these three groups after treatment p = 0.006 (p<0.05).Bleeding time of the third group which was treated with combination of noni fruit and acetosal results in the highest increase compareto the other two groups. In conclusions, combination of noni fruit and acetosal treatment results in increase of bleeding time on mice.

scholarly journals THE USE OF SNOWBALLING TECHNIQUE TO LEARN APPLYING VOCABULARY AFTER THE PANDEMIC THE USE OF SNOWBALLING TECHNIQUE TO LEARN APPLYING VOCABULARY AFTER THE PANDEMIC

2021 ◽  
Vol 7 (4) ◽  
Author(s):  
Tri Setianingsih ◽  
Siti Syafi’atul Qomariyah ◽  
Bq. Zuhrotun Nafisah
Keyword(s):  
Alternative Hypothesis ◽  
Third Grade ◽  
Control Group ◽  
Control Group Design ◽  
The Third ◽  
Third Grade Students ◽  
Post Test ◽  
Quasi Experimental ◽  
Equivalent Control ◽  
Academic Year

The Use of Snowballing Technique to Learn Applying Vocabulary After the Pandemic. This research is aimed at finding out the effectiveness of using snowballing technique to learn applying vocabulary at the third grade students of SMAN 1 Batulayar in academic year 2020/2021. This research is an experimental research with quasi experimental and category of this research is non-equivalent control group design. The population of this research is the third grade students of SMAN 1 Batulayar consist of 62 students. The instrument that will be used to collect the data is test consists of post-test. The data will be analysed by using statistical formula of t-test.The result of data analysis showed that the value of t-test was 4.39 and t-table 2.00. The value of t-testis higher than t-table in significance level0.05 and degree of freedom 62-2. It meant that t-critical value was significant fot this confidence level. Then, alternative hypothesis (Ha) was accepeted and null hypothesis (Ho) was rejected. It could be concluded that there was an effect of using snowballing technique to teach vocabulary at the third grade students of SMAN 1 Batulayar in Academic year 2021/2022.

scholarly journals Hemostatic Effect of Ethanol Extract of Piper betle, Linn Leaves to Male Mice

Molekul ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. 23
Author(s):  
Sadakata Sinulingga ◽  
Subandrate Subandrate ◽  
Bebbi Arisya Kesumaputri ◽  
Galuh Anggraini
Keyword(s):  
Bleeding Time ◽  
Ethanol Extract ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Piper Betle ◽  
Control Group Design ◽  
Minimum Concentration ◽  
Group Design ◽  
Hemostatic Effect

Hemorrhage occurs in most of the dental care. Untreated hemorrhage could cause excessive blood loss, hypotension, and cyanosis. A Natural resource that reported has an hemostatic effect is ethanol extract of betel leaves (Piper betel, Linn).The aim of this study is to find the minimum concentration of ethanol extract of betel leaves which capable of shortening the bleeding time in mice. The experimental study used pretest-posttest with control group design was conducted on 35 mice that divided into 7 group which are negative control, positive control (feracrylum 1%), the ethanol extract of betel leaves 1%, 5%, 10%, 15%, and 20%. All mice were injected heparin intravenously. Mice’s tail was cut at diameter 3 mm and pretest bleeding time was counted. Mice’s tail was recut at diameter 4 mm, given treatment for 5 seconds and posttest bleeding time was counted. Results of paired t-test showed that reduction of bleeding time between pretest and posttest was significant (p<0,050). The enhancement of ethanol extract of betel leaves concentration leads to better hemostatic effect. Results of ANOVA test showed that comparison of posttest bleeding time among groups was significant (p<0,050). The minimum concentration of ethanol extract of betel leaves which capable of shortening the bleeding time in mice is 5%.

scholarly journals Perbedaan Jumlah Lalat Tertangkap Sticky Trap Antara Menggunakan Umpan Ekstrak Buah Durian Dengan Umpan Ekstrak Kayu Manis

2015 ◽  
Vol 13 (3) ◽  
Author(s):  
Yayan Wijayanti ◽  
Winarko . ◽  
Pratiwi Hermiyanti
Keyword(s):  
Design Research ◽  
Sticky Trap ◽  
Control Group ◽  
Fruit Extract ◽  
Control Group Design ◽  
Sticky Traps ◽  
Cinnamon Extract ◽  
Post Test ◽  
Alcohol Solvent ◽  
Quasi Experimental

Given the fact that flies are attracted by strong odors, flies controlling  can be carried out by using scent lure trap. However, flies’ most preferred scent has not been known. This study aimsto determine difference in the number of flies caught on sticky traps between using lures of durianfruit extract and cinnamon extract lure. Durian fruit extracts contains alcohol while cinnamon contains eugenol.This is a quasi-experimental design research with Only Control Group Design Post-Test. This research was conducted in TPS of Bukit Barisan. This study covers the extraction with alcohol solvent. The extraction result was then dropped into the sticky trap and subsequently used to catchflies. The results shows that there were higher average number of flies caught on sticky trap ofcinnamon extract lure with 12-21 flies / trap than those in durian fruit extract trap which were only 10-14 flies / trap. The results of the data analysis by T test shows that there were difference in thenumber of flies caught on sticky traps between using lures of durian fruit extract and cinnamon extract (P = 0.033 <0.05)It is advisable  to use physical ways of using sticky traps with durian fruit or cinnamon . In addition to their safety and environmentally friendly, they are proven to reduce flies population.

scholarly journals UJI EFEKTIFITAS BIOLARVASIDA EKSTRAK ETANOL BUAH LAMPESU (Baccaurea lanceolata) TERHADAP LARVA INSTAR III Culex quinquefasciatus

2020 ◽  
Vol 3 (3) ◽  
pp. 7
Author(s):  
Dea Alfani Nandjan
Keyword(s):  
Culex Quinquefasciatus ◽  
Ethanol Extract ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Chemical Insecticide ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Infection Disease

Filariasis is chronic infection disease caused by worm and carried by Culex quinquefasciatus mosquito. One of theways to controlling mosquitoes vectors are use biolarvacide or chemical insecticide. Chemical insecticide causingresistance Culex quinquefasciatus larvae and toxic for human. This research aim to determine the biolarvacideeffectiviteness of ethanol extract lampesu fruit (Baccaurea lanceolata) to Culex quinquefasciatus larvae instars III.This study was true experimental with a Post test-only control group design. This study used 700 larvae instars III ofCulex quinquefasciatus divided into 7 groups consentration of 0,2%, 0,4%, 0,6%, 0,8% and 1%, the positive control(abate) and negative control (aquadest). The observation was did after treatment in 3 hours, 6 hours, 12  hours and 24hours. The experiment is replicated four times. At 24 hours exposure concentration of 0,6% the test larvae mortalityreached 38% and at concentration of 1% the test larvae mortality reached 30%. In this stuy the concentration of1,531 % was effective to kill larvae with of 50% mortality(LC50) and concentration of 10,729 % was effective to killlarvae with of 90% mortality(LC90). Ethanol Ekstract of Lampesu Fruit (Baccaurea lanceolata) not effective asbiolarvacide ofCulex quinquefasciatus larvae instars III.

scholarly journals EFEKTIFITAS KAPSUL MENGKUDU (Morinda citrifolia) TERHADAP PENURUNAN KADAR GULA DARAH PADA PASIEN DIABETES MELLITUS DI RS BRAWIJAYA

2017 ◽  
Vol 10 (01) ◽  
Author(s):  
Yuni Irianti ◽  
Ngadiani Ngadiani
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Alternative Hypothesis ◽  
Morinda Citrifolia ◽  
Control Group ◽  
Control Group Design ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
Post Test ◽  
Sugar Levels

We report the supplementation of noni (Morinda citrifolia) to decrease blood sugar levels in patients with diabetes mellitus Brawijaya Hospital Surabaya, and noni problems whether supplementation is effective in reducing blood sugar levels in diabetes patients mellitus.The goal of this study was to determine the effectiveness of capsule morinda to decrease blood sugar levels in patients with Diabetes Mellitus in Brawijaya Hospital Surabaya. This type of research is to ekperimem quasi control group design with pre-test and post test. The population in this study are patients with diabetes mellitus in hospital outpatient Brawijaya. The sampling technique with a number of 60 people who were divided into 30 groups of control (can drug from a doctor) and 30 in the experimental group (can medicine from the doctor and consumption of noni capsules) .Instrumen this study is the laboratory results of random blood sugar levels with the tools glucometer ( gluko Dr). Data analysis was performed using univariate and bivariate (parametric test, Kolmogorov-Smirnov test z and Independent T-Test). From the results, no significant difference the difference in the results of pre-test and post-test in the control group and the experiment is p = 0.020 (<0.05), then the alternative hypothesis (Ha) is accepted (the results are meaningful). It is concluded that supplementation of noni effective in helping to decrease blood sugar levels of patients with diabetes mellitus, it is advisable to consume noni capsules and routine checks of blood sugar levels so that the blood sugar levels under control.

scholarly journals EFEK EKSTRAK ETHANOL DAUN KELOR (MORINGA OLEIFERA) TERHADAP PROTEKSI FUNGSI HATI DAN HISTOPATOLOGI TIKUS PUTIH (RATTUS NORVEGICUS) YANG DIINDUKSI KARBONTETRAKLORIDA (CCL4)

2021 ◽  
Vol 21 (1) ◽  
pp. 177-185
Author(s):  
Siti Hardiyanti Nawir ◽  
Peter Kabo ◽  
Ilhamjaya Pattelongi
Keyword(s):  
Liver Function ◽  
Rattus Norvegicus ◽  
Moringa Oleifera ◽  
Ethanol Extract ◽  
Blood Chemistry ◽  
Control Group ◽  
Control Group Design ◽  
Post Test ◽  
Moringa Oleifera Leaves ◽  
One Way Anova

Abstrak Kerusakan hati menjadi salah satu penyakit dengan prevalensi yang tinggi khususnya di negara berkembang. Penelitian ini bertujuan untuk melihat adanya efek ekstrak ethanol daun kelor (Moringa oleifera) terhadap proteksi fungsi hati dan histopatologi tikus putih (Rattus norvegicus) yang diinduksi karbontetraklorida (ccl4). serta menentukan dosis efektif dari kombinasi tersebut. Penelitian ini dilakukan secara eksperimental laboratorium menggunakan metode eksperimen dengan desain post test only control group pada tikus wistar. Tikus dibagi menjadi 5 kelompok, yaitu kelompok kontrol positif (ekstrak kurkuma), kontrol pembanding (NaCMC 1%) dan 3 kelompok pemberian ekstrak dengan 3 variasi dosis masing-masing 250 mg/kgBB, 500 mg/kgBB dan 750 mg/kgBB. Dilakukan pengamatan terhadap uji profil kimia darah yang meliputi SGOT dan SGPT serta dilanjutkan dengan uji histopatologi. Hasil menunjukkan bahwa adanya perbedaan perubahan hasil pengukuran darah fungsi hati (SGOT dan SGPT) antar kelompok selama 8 hari. Hasil menunjukkan bahwa adanya perbedaan perubahan hasil pengukuran profil kimia darah antar kelompok selama perlakuan. Berdasarkan hasil uji one way ANOVA pada pengukuran SGOT dan SGPT terdapat hasil tes bermakna (P<0,05). Hasil uji histopatologi menunjukkan bahwa terdapat perbaikan fungsi dan struktur hati pada kelompok pemberian ekstrak etanol daun kelor. Dapat disimpulkan bahwa ekstrak etanol daun kelor (Moringa oleifera) memiliki kemampuan sebagai hepatoprotektor terhadap fungsi hati pada dosis 750 mg/kgBB. Abstract Liver damage is one of the diseases with high prevalence especially in developing countries. This study aims to see the effect of ethanol extract of Moringa oleifera leaves on liver function protection and histopathology of white rat (Rattus norvegicus) induced by carbontetrachloride (CCl4). and determine the effective dose of the combination. This research was conducted experimentally using a laboratory experimental method with a post test only control group design in wistar rats. Rats were divided into 5 groups, namely the positive control group (curkuma extract), comparative control (NaCMC 1%) and 3 groups giving extracts with 3 variations of each dose of 250 mg / kgBB, 500 mg / kgBB and 750 mg / kgBB. Observations were made on the blood chemistry profile test which included SGOT and SGPT and continued with histopathological testing. The results showed that there were differences in changes in the results of liver function blood measurements (SGOT and SGPT) between groups for 8 days. The results showed that there were differences in changes in the measurement results of blood chemistry profiles between groups during treatment. Based on the results of the one way ANOVA test on SGOT and SGPT measurements there were significant test results (P <0.05). The results of histopathological tests showed that there was an improvement in liver function and structure in the group given ethanol extract of kelor leaves. It can be concluded that the ethanol extract of Moringa oleifera leaves has the ability as a hepatoprotector of liver function at a dose of 750 mg / kgBB.

scholarly journals The Effect of Co-Administration of Telang Leaves Ethanolic Extract Towards Fluoxetin’s Sedative Effect on Male Balb/C Mice Based on Sleeping Duration Parameter

2017 ◽  
Vol 6 (1) ◽  
pp. 7
Author(s):  
Anif Nur Artanti ◽  
Maria Ulfah
Keyword(s):  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Sedative Effect ◽  
Control Group ◽  
Phytochemical Analysis ◽  
Control Group Design ◽  
Group Design ◽  
Sleep Analysis ◽  
Post Test ◽  
The Mean

One of Telang plant’s advantages is its activity as sedative agent. Previous studies indicate that Telang plant has anticonvulsant activity on mice at certain dose. This study was conducted to find out the sedative effect of Telang plant, particularly its leaf, when being co-administered with fluoxetin. Phytochemical analysis was carried out qualitatively on Telang ethanolic extract leaves (TEE) to find out the content of chemical compound first.This study was an experimental research with post-test only control group design, employing male balb/c mice. The effect of Telang ethanolic extract co-administration with fluoxetin was observed. The parameter being used in the study was the duration of sleep. Analysis was done by comparing mice sleeping duration prior to administration of fluoxetin alone and in combination with Telang ethanolic extract. The data was then analyzed using SPSS 17.0 for Windows.The results showed that TEE contained tannin, saponin, and flavonoid compounds, and co-administration of TEE and fluoxetin at various doses could provide sedative effect on mice. The co-administration of 400 mg/kgBW extract and 15 mg/kgBW fluoxetin could provide the mean sleeping duration 43 minutes longer than positive control.Keywords:  telang leaves ethanol extract, fluoxetin, sleeping duration

scholarly journals The effect of papaya leaf extract (Carica papaya l.) to the bleeding time on mice with trombositopenia

2018 ◽  
Vol 6 (3) ◽  
pp. 133
Author(s):  
Saktya Yudha Ardhi Utama
Keyword(s):  
Treatment Group ◽  
Leaf Extract ◽  
Carica Papaya ◽  
Bleeding Time ◽  
Control Group ◽  
Control Group Design ◽  
Treatment Groups ◽  
Group Design ◽  
Post Test ◽  
Mean Time

<p align="center"><strong>ABSTRAK</strong></p><p><strong>Latar belakang: </strong>Trombositopenia merupakan suatu keadaan jumlah trombosit di bawah 150.000/mm<sup>3</sup>, hal ini dapat menyebabkan perdarahan yang apabila tidak ditangani dengan baik dapat berujung pada kematian. Beberapa tindakan yang dapat dilakukan untuk mengatasi  trombositopenia, salah satunya adalah dengan tanaman daun pepaya.</p><p><strong>Tujuan:</strong> untuk menganalisis pengaruh pemberian ekstrak daun pepaya terhadap <em>bleeding time</em> (waktu perdarahan).</p><p><strong>Metode : </strong>Desain penelitian ini menggunakan <em>true experimental</em> dengan rancangan <em>post test only control group design</em>. Sampel dalam penelitian ini sejumlah 30 ekor mencit jantan (<em>Mus musculus</em>) yang dibagi menjadi lima kelompok. Kelompok pertama sebagai kelompok kontrol negatif (CMC Na 0,5%), kelompok kedua sebagai kontrol positif (CMC Na 0,5%)<a href="file:///D:/peer/VOLUME%206/VOLUME%206%20NOMOR%203/KIRIM%20LINTANG%20VOLUME%206%20ISSUE%203,%202018%20(AKREDITASI)/6.%20Revisi%20Publish%20JGDI%20(1)_Yudha.rtf#_msocom_1">[a1]</a> <a href="file:///D:/peer/VOLUME%206/VOLUME%206%20NOMOR%203/KIRIM%20LINTANG%20VOLUME%206%20ISSUE%203,%202018%20(AKREDITASI)/6.%20Revisi%20Publish%20JGDI%20(1)_Yudha.rtf#_msocom_2">[A2]</a> , kelompok ketiga diberi esktrak etanol 96% daun pepaya dosis 0,5g/kgBB, kelompok keempat diberi esktrak etanol 96% daun pepaya dosis 1g/kgBB, kelompok kelima diberi esktrak etanol 96% daun pepaya dosis 2g/kgBB. Pengumpulan data menggunakan lembar pengukuran <em>bleeding time</em>, yang dianalisa dengan uji ANOVA.</p><p><strong>Hasil: </strong>Hasil penelitian ini menunjukkan bahwa didapatkan nilai <em>p</em>&lt;0.0001 dengan rerata waktu paling cepat antara kelompok perlakuan yaitu kelompok perlakuan dengan dosis 2g/kgBB (2.74±0.14). Hal ini menunjukkan bahwa terdapat perbedaan signifikan antar semua kelompok. <a href="file:///D:/peer/VOLUME%206/VOLUME%206%20NOMOR%203/KIRIM%20LINTANG%20VOLUME%206%20ISSUE%203,%202018%20(AKREDITASI)/6.%20Revisi%20Publish%20JGDI%20(1)_Yudha.rtf#_msocom_3">[a3]</a> <a href="file:///D:/peer/VOLUME%206/VOLUME%206%20NOMOR%203/KIRIM%20LINTANG%20VOLUME%206%20ISSUE%203,%202018%20(AKREDITASI)/6.%20Revisi%20Publish%20JGDI%20(1)_Yudha.rtf#_msocom_4">[A4]</a> </p><p><strong>Kesimpulan: </strong>Kesimpulan dari penelitian ini adalah pemberian ekstrak daun pepaya (<em>Carica papaya L.</em>) dapat mempercepat <em>bleeding time</em> (waktu perdarahan).</p><p><strong>KATA KUNCI: </strong>daun pepaya; <em>bleeding time, </em>trombositopenia<strong></strong></p><p align="center"> </p><p align="center"><strong>ABSTRACT</strong></p><p><strong><em>Background</em></strong><strong>: </strong>Thrombocytopenia is a condition of platelet counts below 150,000/mm<sup>3</sup>, this may cause bleeding which, if not handled properly, may lead to death. Some actions that can be done to overcome thrombocytopenia, one of which is with papaya leaf.</p><p><strong>Objectives:</strong> This study aims to analyze the effect of giving papaya leaf extract to bleeding time.</p><p><strong><em>Methods:</em></strong><strong> </strong>This research design uses true experimental with design of post-test only control group design. The sample in this study were 30 male mice (<em>Mus musculus</em>) divided into five groups. The first group as the negative control group (CMC Na 0.5%), the second group as the positive control (CMC Na 0.5%), the third group was given ethanol 96% extract papaya leaf dose 0.5g/kgBW, the fourth group was given ethanol 96% extract papaya leaf dose 1g/kgBW, the fifth group was given ethanol 96% extract papaya leaf dose 2g/kgBW. Data collection using measurement sheet of  bleeding time which were analyzed by ANOVA test.</p><p><strong><em>Results:</em></strong><strong> </strong>The results of this study showed that p&lt;0.0001 the fastest mean time occur between treatment groups that is treatment group with dose 2g/kgBW (2.74±0.14). In the bleeding time variables p&lt;0.0001 the fastest mean time occur between treatment groups that is treatment group with dose 2g/kgBW (2.74±0.14). This result shows that there are significant differences between every groups.</p><p><strong><em>Conclusion:</em></strong><strong> </strong>The conclusion of this research is giving papaya leaf extract can increase bleeding time.</p><p> </p><p><strong>KEYWORDS: </strong>leaf of papaya, bleeding time, thrombocytopenia.</p><p> </p>

scholarly journals Pengaruh Senam Nifas terhadap Penurunan Tinggi Fundus Uteri pada Ibu Post Partum di RSUP DR. M. Djamil Padang

2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Nurniati Tianastia Rullynil ◽  
Ermawati Ermawati ◽  
Lisma Evareny
Keyword(s):  
Uterine Contraction ◽  
Post Partum ◽  
Intervention Group ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
The Third ◽  
Uterine Involution ◽  
Maternal Morbidity And Mortality ◽  
Post Test

AbstrakPerdarahan merupakan penyebab utama kesakitan dan kematian ibu pada masa nifas, dimana 50%-60% karena kegagalan miometrium berkontraksi secara sempurna. Salah satu asuhan untuk memaksimalkan kontraksi uterus pada masa nifas adalah dengan melaksanakan senam nifas, guna mempercepat proses involusi uteri. Tujuan penelitian ini adalah untuk mengetahui pengaruh senam nifas terhadap penurunan tinggi fundus uteri (TFU) pada ibu post partum. Penelitian ini merupakan studi eksperimental dengan Post Test Only Control Group Design. Alat yang digunakan dalam penelitian berupa kaliper pelvimetri. Diberikan perlakuan senam nifas pada kelompok intervensi dan tidak senam nifas pada kelompok kontrol, kemudian dilakukan pengukuran tinggi fundus uteri hari ke-1, hari ke-3 dan hari ke-6. Data dianalisa menggunakan Uji General Linier Model (GLM). Rerata TFU hari ke-1 pada kelompok intervensi 12,37±0,72 dan 12,42±0,54 pada kelompok kontrol. Rerata TFU hari ke-3 pada kelompok intervensi 9,00±0,94 dan 9,87±0,75 pada kelompok kontrol. Sedangkan rerata TFU hari ke-6 pada kelompok intervensi 5,72±0,88 dan 7,37±0,68 pada kelompok kontrol. Terdapat perbedaan yang signifikan penurunan tinggi fundus uteri antara kedua kelompok pada hari ke-3 (p=0,00) dan hari ke 6 (p=0,00). Dari hasil penelitian dapat disimpulkan bahwa senam nifas berpengaruh terhadap penurunan tinggi fundus uteri. Penurunan tinggi fundus uteri pada kelompok intervensi lebih turun dibanding kelompok kontrol.Kata kunci: senam nifas, tinggi fundus uteri, post partumAbstractHemorrhage is a major cause of maternal morbidity and mortality in the puerperium, about 50%-60% of hemorrhage occurs due to failure of myometrium to contract completely. One care to maximaze uterine contraction during the puerperium is by implementing parturition gymnastics in order to accelarate the process of uterine involution. The purpose of this study was to determine the effect of parturition gymnastics on a decreasing of fundal height of maternal postpartum.This was experimental study with Post Test Only Control Group Design. The tool used in this study was pelvimetry caliper. Parturition gymnastics was given to intervention group but the control group did not treated with parturition gymnastics, then fundal height was measured on the first day, third day, and sixth day. Data were analyzed by using General Linear Model (GLM) test. Mean of fundal height on the first day on the intervention group was 12.37±0.72 and 12.42±0.54 on the control group. Mean of fundal height on the third day was 9.00±0.94 on the intervention group and 9.87±0.75 on the control group. Meanwhile, mean of fundal height on the sixth day on the intervention group was 5.72±0.88 and 7.37±0.68 on the control group. There was significant decrease of fundal height between the two groups on the third day 3 at (p=0.00) and the sixth day at (p=0.00). From the research results, it can be concluded that parturition gymnastic has an effect on the decreasing of fundal height. The decline of fundal height on the intervention group is more decreasing than that of on the control

scholarly journals Uji konsentrasi hambat minimum (KHM) ekstrak buah mengkudu (Morinda citrifolia L.) terhadap pertumbuhan Streptococcus mutans

e-GIGI ◽  
2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Jecklin Makolit ◽  
Olivia A. Waworuntu ◽  
Michael A. Leman
Keyword(s):  
Minimum Inhibitory Concentration ◽  
Streptococcus Mutans ◽  
Inhibitory Concentration ◽  
Morinda Citrifolia ◽  
Control Group ◽  
Dilution Method ◽  
Fruit Extract ◽  
Control Group Design ◽  
Group Design ◽  
Serial Dilution Method

Abstract: Noni fruit (Morinda cittrifolia L.) is an herbal plant that contains antibacterial substances, inter alia acubin, lasperuloside, alizarin, and some antraquinons, that have been proved to inhibit the growth of Streptococcus mutans. This study was aimed to obtain the minimum inhibitory concentration (MIC) of noni fruit extract (Morinda citrifolia L.) against the growth of Streptococcus mutans. This was a true experimental study with a randomized pretest-posttest control group design. This study used a serial dilution method with turbidimetry and spectrophotometry tests. Noni fruit was extracted by using maceration method with 96% ethanol. Streptococcus mutans bacteria were obtained from pure stock of Microbiology Laboratory of Pharmacy Program Study, University of Sam Ratulangi Manado. The results showed that the MIC of noni fruit extract against the growth of Streptococcus mutans was at 50% of concentration. Conclusion: The minimum inhibitory concentration of Morinda citrifolia L. extract against the growth of Streptococcus mutans was 50%.Keywords: noni fruit (Morinda citrifolia L.), Streptococcus mutans, MIC Abstrak: Buah mengkudu (Morinda citrifolia, L) merupakan tanaman herbal dengan kandungan bahan berkhasiat antibakterial seperti acubin, lasperuloside, alizarin, dan beberapa zat antraquinon yang terbukti dapat menghambat pertumbuhan Streptococcus mutans. Penelitian ini bertujuan untuk mengetahui konsentrasi hambat minimum (KHM) dari ekstrak buah mengkudu (Morinda citrifolia L.) terhadap pertumbuhan Streptococcus mutans. Jenis penelitian ialah eksperimental murni dengan randomized pretest-posttest control group design. Metode yang digunakan yaitu metode serial dilusi dengan metode pengujian turbidimetri dan spektrofotometri. Buah mengkudu diekstraksi dengan metode maserasi menggunakan pelarut etanol 96%. Bakteri Streptococcus mutans diambil dari stok bakteri murni Laboratorium Mikrobiologi Program Studi Farmasi Fakultas MIPA Universitas Sam Ratulangi. Hasil penelitian menunjukkan bahwa KHM ekstrak buah mengkudu terhadap pertumbuhan Streptococcus mutans pada konsentrasi 50%. Simpulan: Konsentrasi hambat minimum ekstrak buah mengkudu (Morinda citrifolia L.) terhadap pertumbuhan Streptococcus mutans pada konsentrasi 50%.Kata kunci: buah mengkudu (Morinda citrifolia L.), Streptococcus mutans, KHM

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