Gambaran Daya Terima Minuman Sari Buah Pedada (Sonneratia sp.) dengan Penambahan Gula Stevia (Stevia rebaudiana)

One type of coastal plant in the mangrove forest is the pedada (Sonneratia sp.). This fruit has high nutritional value and has the potential to be processed into food products. This fruit is still rarely used because of its sour taste. One form of food processed from pedada fruit is pedada juice drink. The purpose of this study was to describe the acceptance of the parameters of color, aroma, texture, taste, and overall acceptance in the form of selecting the best formulation, which was analyzed using the exponential method of pedada fruit juice drinks. A descriptive analysis within the experimental design was applied in this research. There were 5 samples in this study, namely A1 positive control (200 g, 70% sucrose sugar), A2 negative control (200 g pedada, 0% stevia sugar), A3 (200 g pedada, 9% stevia sugar), A4 (pedada 200 g, 18% stevia sugar), and A5 (200 g pedada, 36% stevia sugar). The acceptance test used the hedonic method with 40 consumer panelists aged 17-35 years. This research was conducted in May-August 2020. The manufacture of pedada fruit juice drinks and acceptance testing were carried out at home. The results showed that the A4 sample of 200 g of pedada fruit with the addition of 18% stevia sugar obtained the highest score on the acceptability of pedada fruit juice drinks and overall acceptance. The average results of each color, aroma, texture, and taste acceptability parameter were 3.9, 3.9, 4.0, and 4.0, respectively. Keywords: Acceptance; fruit juice; pedada; stevia sugar ABSTRAK Indonesia kaya akan hasil alamnya seperti berbagai jenis hutan yang salah satunya adalah hutan mangrove. Hutan mangrove itu sendiri memiliki berbagai jenis tumbuhan pantai seperti pedada atau Sonneratia sp. Buah ini memiliki nilai gizi yang tinggi dan berpotensi untuk diolah menjadi produk pangan. Buah ini masih jarang digunakan karena rasanya yang asam. Salah satu bentuk pengolahan makanan dari buah pedada adalah minuman sari buah pedada. Adapun tujuan dari penelitian ini yaitu untuk mendeskripsikan penerimaan terhadap parameter warna, aroma, tekstur, dan rasa serta penerimaan secara keseluruhan berupa pemilihan formulasi terbaik yang dianalisis menggunakan metode eksponensial minuman sari buah pedada. Penelitian ini merupakan penelitian eksperimental dengan desain analisis deskriptif murni. Sampel dalam penelitian ini sebanyak 5 sampel yaitu kontrol positif A1 (200 g, gula sukrosa 70%), kontrol negatif A2 (200 g pedada, gula stevia 0%), A3 (200 g pedada, gula stevia 9%), A4 ( pedada 200 g, gula stevia 18%), A5 (200 g pedada, gula stevia 36%). Uji penerimaan menggunakan metode hedonis dengan 40 panelis konsumen berusia 17-35 tahun. Penelitian ini dilakukan pada bulan Mei-Agustus 2020, pembuatan minuman sari buah pedada dan uji daya terima dilakukan di rumah. Akseptabilitas minuman sari buah pedada dan penerimaan keseluruhan yaitu sampel minuman A4 buah pedada 200 g dengan penambahan gula stevia 18%, diperoleh skor rata-rata tertinggi (4,0) dengan hasil rata-rata masing-masing parameter akseptabilitas warna 3.9, aroma 3.9, tekstur 4.0, dan rasa 4.0. Kata Kunci: Daya terima, gula stevia, pedada, sari buah

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Microbiological Sealing Analysis of a Tapered Connection and External Hexagon System

International Journal of Dentistry ◽

10.1155/2017/3849085 ◽

2017 ◽

Vol 2017 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Gardel Nepomuceno Costa ◽

Elizabeth Ferreira Martinez ◽

Aluísio Martins de Oliveira Ruellas ◽

Daiane Cristina Peruzzo ◽

Júlio Cesar Joly ◽

...

Keyword(s):

Descriptive Analysis ◽

In Vitro Study ◽

Positive Control ◽

Negative Control ◽

Microbiological Analysis ◽

Significance Level ◽

Implant Abutment ◽

Bacterial Leakage ◽

Tapered Connection

Considering the variety of implant connection systems available in the market and the contrasting literature regarding tapered connection systems in terms of bacterial leakage, the aim of this in vitro study was to compare the effectiveness of the bacterial seal at the implant/abutment interface between an external hexagon and a tapered connection system. Twelve sets of indexed tapered connection components and twelve sets of external hexagon connection components were used for microbiological analysis. In addition, for each model, an implant with its respective prosthetic abutment was used as a negative control and another as a positive control of microbial contamination. Failure of the abutment/implant interface seal was observed via turbidity or presence of deposits in the culture. Descriptive analysis of the data and relative frequency (percentage) as well as Fisher’s exact test were used at a significance level of 5%. Two of ten (20%) external hexagon specimens showed contamination against 0/10 (0%) tapered connection implants. In conclusion, both implant/abutment connections were able to prevent bacterial leakage in vitro.

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Development and effect of a Lactobacillus plantarum inoculant on quality of maize grain silage

Biotechnology in Animal Husbandry ◽

10.2298/bah2002239d ◽

2020 ◽

Vol 36 (2) ◽

pp. 239-250

Author(s):

Snezana Djordjevic ◽

Violeta Mandic ◽

Nikola Djordjevic

Keyword(s):

Phylogenetic Analysis ◽

Lactic Acid ◽

Nutritional Value ◽

Positive Control ◽

Negative Control ◽

High Moisture ◽

Acid Detergent Fibre ◽

Maize Grain ◽

Competitive Product

The main aim of these studies was the characterisation and identification of lactic acid (LAB) bacteria isolated from untreated silage, and the effect of selected bacteria (inoculant was called Silko for maize) on ensiling of maize high-moisture grain. Four isolates of L(L1, L2, L3 and L4) were characterised by the use of phenotypic assays and identified by phylogenetic analysis of 16S rRNA as L. plantarum. The fresh maize high-moisture grain was ensiled with a Silko for maize inoculant, inoculant available in the market (positive control) and no additive (untreated; negative control). After 60 days of ensiling, the results showed that the chemical composition and fermentation characteristics were better in treated silages with inoculants compared to the negative control. The contents of ash, fat and lactic acid (LA) were significantly higher in the silages treated with inoculants than in negative control. In comparison, the contents of cellulose, acid detergent fibre (ADF), neutral detergent fibre (NDF), NH3-N/total nitrogen and butyric acids (BA) were considerably lower in silage treated with Silko for maize compared to the positive control. The Silko for maize improve nutritional value and fermentation of maize grain silage and is a competitive product on the market.

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Quantitative Descriptive Analysis and Acceptance Testing of Yogurt with no Added Sugar

Journal of Food Research ◽

10.5539/jfr.v9n2p7 ◽

2020 ◽

Vol 9 (2) ◽

pp. 7

Author(s):

Claudia Regina S. Amaral ◽

Priscila Becker Siqueira ◽

Luciane Yuri Yoshiara ◽

Edgar Nascimento ◽

Rozilaine A. P. Gomes de Faria ◽

...

Keyword(s):

Phenolic Compounds ◽

Descriptive Analysis ◽

Starter Cultures ◽

Sensory Profile ◽

Acceptance Testing ◽

Total Phenolic ◽

Acceptance Test ◽

Quantitative Descriptive Analysis ◽

Quantitative Descriptive ◽

Hancornia Speciosa

This study aimed to evaluate the effect of sucralose added in Greek Yogurt flavored with araticum (Annona crassiflora) and mangaba (Hancornia speciosa) through sensory characterization. The Greek yogurt was prepared with skimmed milk, inoculated starter cultures, filtered and it was supplemented with the appropriate amount of sucralose, added sweetened and pasteurized fruit pulp (araticum or mangaba). The total phenolic compounds and texture were performed and sensory analyses were carried out by Quantitative descriptive analysis (QDA) and acceptance test in storage for 7 and 28 days. The QDA results showed that the main attributes were color, lightness, creaminess, presence of particles, fullness, and aroma. Eighty percent and 85% of the panelists were said they would buy the araticum Greek yogurt and the mangaba Greek yogurt after 7 days of storage, respectively. Additionally, 71% and 77% were said they would buy the araticum Greek yogurt and the mangaba Greek yogurt after storage for 28 days at 4ºC, respectively. The sensory profile and acceptance test results of the Greek yogurts developed indicated no perceptions caused by adding sucralose to the yogurt after storage for different times. The highest concentration of phenolic compounds in the araticum Greek yogurt was perceived by the panelists in aroma and flavor attributes. Changing sucrose to sucralose was not imperceptible under the storage and consumption conditions.

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PENGARUH EKSTRAK ETANOL BUAH LABU SIAM (SECHIUM EDULE JACQ.SWARTZ.) TERHADAP KADAR INTERLEUKIN 6 DAN HISTOPATOLOGI PANKREAS MENCIT HIPERGLIKEMIA YANG DIINDUKSI STREPTOZOTOCIN (STZ)

Elisabeth Health Jurnal ◽

10.52317/ehj.v2i1.273 ◽

2017 ◽

Vol 2 (1) ◽

pp. 60-64

Author(s):

Paska Ramawati Situmorang

Keyword(s):

Interleukin 6 ◽

Descriptive Analysis ◽

Ethanol Extract ◽

Negative Control Group ◽

Positive Control ◽

Negative Control ◽

Control Group ◽

Mice Model ◽

Sechium Edule ◽

Size Ofthe

Diabetes mellitus now becomes a global serious theat with continues encreasingly prevalence. Ethanol extract of squash fruit Chayotte (Sechium edule) is a plant that contains flavonoidsareanti-inflammatory. The objective of this study was to determine the effect of ethanol extract of Squash fruit Chayotte (Sechium edule) to Interleukin 6 level and increasedthe size ofthe diameter of the pancreas in STZ-induced hyperglycemic mice model. Goals : This research is experimental research uses Post test randomized controlled group design upon male mice, and divided into 4 groups; negative control group, positive control group is treated with streptozotocin at a dose of 60 mg/kg weight, and groups of therapy (dosage 100 gram/kg weight, 200 gram/kg weight). Methods : The measurement of the level interleleukin 6 (IL-6) used ELISA method and the description of histopatoligy pancreas. The data analysis of level IL-6 level uses One Way ANOVA (α = 0,005) and pancreas histology image used descriptive analysis. Result : The results showed a decrease in the levels of IL-6, although not significant if it’s compared to the positive control. The preparat histopathology pancreas observation increased diameter which showed widening of cell β of pancreas. Conclution : The conclusion of this research was that ethanol extract of squash fruit can reduce levels IL-6 and prevent the hiperglikemia mice pancreas damages

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UJI AKTIVITAS ANTIBAKTERI EKSTRAK BIJI BUAH DUKU Lansium domesticum TERHADAP BAKTERI STAPHYLOCOCUS AUREUS DAN ESCHERICHIA COLI

PHARMACON ◽

10.35799/pha.10.2021.34030 ◽

2021 ◽

Vol 10 (2) ◽

pp. 818

Author(s):

Albrita Pehino ◽

Fatimawali Fatimawali ◽

Elly J. Suoth

Keyword(s):

Escherichia Coli ◽

Staphylococcus Aureus ◽

Antibacterial Activity ◽

Nutritional Value ◽

Positive Control ◽

Negative Control ◽

Diffusion Method ◽

Activity Test ◽

Solution Studies ◽

Lansium Domesticum

ABSTRACT Duku (Lansium domesticum) provides many benefits for the community. Apart from the fruit which has high nutritional value, duku is believed by the community to have benefits. The study aims to learn about the antibacterial extract of my seed against the staphylococus aureus and escherichia coli. This study used the meseration method with ethanol as a solvent. The antibacterial activity test used the well diffusion method with a concentration of 10%, 20%, 30%, 40%. The positive control used was Ciprofloxacin and the negative control used was the CMC solution. Studies show that the suppression of extract is 10%, 20%, 30%, and 40% staphylococus aureus, the average drip zone is 11.3mm, 13.3mm, 13.6mm, 11,3mm, and escherichia coli, on average, 10 mm, 9,3mm, 10,3mm, 12,6 mm. The results suggest that the extract of the duku fruit has antibacterial activity against the growth of the staphylococcus aureus and escherichia coli. Keywords: Duku seed, Antibacterial, Antibacterial activity ABSTRAK Duku (Lansium domesticum) banyak memberikan manfaat bagi masyarakat. Selain buahnya yang mempunyai nilai gizi tinggi, duku dipercaya masyarakat memiliki manfaat untuk kesehatan. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak biji duku terhadap bakteri staphylococus aureus dan Escherichia coli. Penelitian ini menggunakan metode maserasi dengan pelarut etanol. Uji aktivitas antibakteri menggunakan metode difusi sumuran dengan konsentrasi 10%, 20%, 30%, 40%. Kontrol positif yang digunakan adalah Ciprofloxacin dan kontrol negatif yang digunakan adalah larutan CMC. Hasil penelitian menunjukan bahwa daya hambat ekstrak dengan konsentrasi 10%, 20%, 30%, dan 40% Staphylococcus aureus rata-rata zona beningnya 11,3mm, 13,3mm, 13,6mm, 11,3mm, dan Escherichia coli rata-rata zona beningnya 10 mm, 9,3mm, 10,3mm, 12,6 mm. Dari hasil yang didapatkan disimpulkan bahwa ekstrak biji buah duku memiliki aktivitas antibakteri terhadap pertumbuhan bakteri Staphylococcus aureus dan Escherichia coli. Kata Kunci:Biji buah duku, Antibakteri, Aktivitas antibakteri

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Safety of Bioinsecticide Ekstract Sugar Apple Seed’s Granule (Annona squamosa L.) on Histology of White Rat (Rattus norvegicus B.)

International Journal of Recent Technology and Engineering - 2 ◽

10.35940/ijrte.b2137.078219 ◽

2019 ◽

Vol 8 (2) ◽

pp. 1495-1498

Keyword(s):

Rattus Norvegicus ◽

Blood Circulation ◽

Descriptive Analysis ◽

Positive Control ◽

Negative Control ◽

Field Of View ◽

Annona Squamosa ◽

Toxic Compounds ◽

Tubular Cells ◽

Apple Seeds

The granules of sugar apple seeds extract (Annona squamosa L.) have been taken as the natural larvacide an economical in eradicating mosquito flicks of Aedes aegypti L. because of its the content of toxic compounds such as acetogenin, alkaloids, and flavonoids. In its use it is feared to cause toxic in the environment, especially the class of mammals as non-target animals, especially kidney organ. The kidney is an organ that is susceptible to toxic effects, since it receives 25-30% of the blood circulation to be cleaned, so that as a filtration organ there is a possibility of pathological changes. This study aims to determine the effect granules of sugar apple seeds extract (Annona squamosa L.) on the histology of white rat (Rattus norvegicus B.). Kidney histology observed as fat degeneration, hydrophic degeneration, and necrosis of tubular cells occurred in one field of view. The concentration given was 1 mg, 2 mg, 4 mg, and 8 mg while the negative control induced 2 ml aquades and positive control using abate 100 mg for 14 days with sonde method. The analysis used in this research is descriptive analysis with scoring. The results showed that granules of sugar apple seeds ex

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Ingredients of Active Compounds and Anti-Diabetic Test of Water Extract of Lannea coromandelica (Houtt) Merr. On Wistar Rats

Acta Veterinaria Indonesiana ◽

10.29244/avi...116-122 ◽

2021 ◽

pp. 116-122

Author(s):

Nona Rahmaida Puetri ◽

Rita Marleta Dewi ◽

Sahrul ◽

Yasir ◽

Munawir Annasri

Keyword(s):

Blood Glucose ◽

Wistar Rats ◽

Descriptive Analysis ◽

Water Extract ◽

Positive Control ◽

Negative Control ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Lannea Coromandelica ◽

Sugar Levels

Leaves of Lannea coromandelica (Houtt.) Merr. is one of the plants found in Aceh. This study aims to determine the effect of giving water extract of Lannea coromandellica (Houtt.) Merr. against STZ-induced blood sugar levels of wistar rats. The experimental study used a sample of 25 male and 15 female Wistar rats. This research is experimental with a sample of 25 male and 15 female of Wistar rats. The treatments were given, namely negative control (aquades), positive control (metformin), 50 mg EALC, 100 mg EALC, and 150 mg EALC. The data obtained will be analyzed by using the Kruskal Wallis test to obtain the effectiveness of the treatment and also a descriptive analysis for the average reduction in blood glucose levels. Macro and histological observations were also carried out on the liver and pancreas. The results obtained from the Kruskal Wallis test results showed that there was no effect of EALC on changes in the decrease in blood glucose levels of wistar rats for 14 days of treatment. Observation of the macro organs showed pancreas had a changes. While the histological observations pancreas and liver showed changes. The results of this study indicate that the effectiveness of EALC is not proven to have an effect, this is presumably because the extract concentration is too small so it is not enough to work optimally. Phytochemical test shows that EALC contains flavonoids, steroids, phenolics, tannins, saponins and alkaloids.

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Aktivitas Antifungi Air Perasan Bawang Merah (Allium ascalonicum L.) Terhadap Candida albicans Secara In Vitro

Jurnal Ilmu Kedokteran ◽

10.26891/jik.v9i2.2015.71-77 ◽

2017 ◽

Vol 9 (2) ◽

pp. 71

Author(s):

Nurhasanah Nurhasanah ◽

Fauzia Andrini ◽

Yulis Hamidy

Keyword(s):

Candida Albicans ◽

Antifungal Activity ◽

Allium Sativum ◽

Fungicidal Activity ◽

Positive Control ◽

Negative Control ◽

Randomized Design ◽

Significant Difference ◽

Completely Randomized Design

Shallot (Allium ascalonicum L.) has been known as traditional medicine. Shallot which has same genus with garlic(Allium sativum L.) contains allicin that is also found in garlic and has been suspected has fungicidal activity toCandida albicans. It is supported by several researches. Therefore, shallot is suspected has antifungal activity too.The aim of this research was to know antifungal activity of shallot’s water extortion againsts Candida albicans invitro. This was a laboratory experimental research which used completely randomized design, with diffusion method.Shallot’s water extortion was devided into three concentrations, there were 50%, 100% and 200%. Ketoconazole 2%was positive control and aquadest was negative control. The result of this research based on analysis of varians(Anova), there was significant difference between several treatments and was confirmed with Duncan New MultipleRange Test (DNMRT) p<0,05, there was significant difference between 100% shallot’s water extortion with othertreatments, but there was no significant difference between 50% shallot’s water extortion with 200% shallot’s. Theconclusion was shallot’s water extortion had antifungal activity againsts Candida albicans with the best concentration100%, but it was lower than ketoconazole 2%.

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The Comparison of Ostecyte in the Pressure area and Tension area on Tooth Movement Because of Hyperbaric Oxygen Therapy

DENTA ◽

10.30649/denta.v12i1.162 ◽

2018 ◽

Vol 12 (1) ◽

pp. 34

Author(s):

Arya Barahmanta ◽

Muhammad Faizal Winaris ◽

Pambudi Raharjo

Keyword(s):

Hyperbaric Oxygen ◽

Oxygen Therapy ◽

Tooth Movement ◽

Bone Remodelling ◽

Orthodontic Tooth Movement ◽

Negative Control Group ◽

Positive Control ◽

Negative Control ◽

Control Group ◽

Pressure Area

Background: Orthodontic tooth movement is a interaction prosess of resorption and deposition of bone remodeling. Orthodontic tooth movement by mechanical strength causes changes in alveolar bone. Osteocyte is an essential cell to respond bone remodelling. Hyperbaric Oxygen Therapy affects production of osteocyte because it can release Reactive Oxygen Species (ROS) and Nitrid Oxide (NO). Purpose: To determine the difference number of osteocyte in pressure and tension area during tooth movement by adjuvant of Hyperbaric Oxygen 2,4 ATA during 7 days starting on day 8 to day 14. Materials and Methods: This research used Completery Randomized Control Group Post Test Only Design. 36 cavia cobaya (male) were divided into 3 groups randomly : the negative control groups, positive control group, and treatment group. Preparat staining used Hematoxylin Eosin (HE) and calculated on microscop 1000x with 20 field of view. Data analyses used one way ANOVA and LSD test then compared each area by using paired T test. Result: The data showed that the treatment group (P=10,67) tension area has the highest number of osteocyte than negative control group (K-=3,67), positive control (K+=7,42). In the pressure area showed that negative control group (K-=5,00) has the highest than positive control group (K+=3,83) and treatment (P=3,25). Conclusion: Therapy HBO 2,4 ATA 7 days starting on day 8 to day 14 is could increase osteocyte in the tissue to stimulate process of bone remodelling.<pre> </pre>Keywords: Hyperbaric Oxygen, Tooth movement, Bone remodeling, Osteocyte Correspondence: Arya Brahmanta, Department of Orthodonty, Faculty of Dentistry, Hang Tuah University, Arif Rahman Hakim 150, Surabaya, Phone 031-5945864, Email: <a href="mailto:[email protected]">arya.brahmanta@hangtuah.ac.id</a>

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UJI AKTIVITAS HEPATOPROTEKTOR KOMBINASI EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius roxb) DAN KAYU MANIS (Cinnamomum burmanii) TERHADAP KADAR MDA YANG DIINDUKSI PARASETAMOL

Jurnal Kesehatan Kusuma Husada ◽

10.34035/jk.v12i1.580 ◽

2020 ◽

pp. 68-73

Author(s):

Yuni Asri Mulatsih Agami ◽

Eka Wisnu Kusuma

Keyword(s):

Oxidative Stress ◽

Ethanol Extract ◽

Optimal Dose ◽

Experimental Methods ◽

Positive Control ◽

Negative Control ◽

Male Rats ◽

Negative Group ◽

Ic50 Value ◽

Dose Combination

Kasus penyakit hati semakin meningkat seiring penggunaan senyawa hepatotoksin salah satunya karena penggunaan parasetamol dengan dosis berlebih. Hal tersebut dapat meningkatkan produksi radikal bebas sehingga memicu terjadinya stress oksidatif yang dapat menimbulkan kerusakan jaringan yang ditandai dengan peningkatan kadar Malondialdehyde (MDA). Stress oksidatif dapat diatasi dengan antioksidan dari berbagai tanaman. Kulit kayu manis memiliki aktivitas antioksidan dengan nilai IC50 53ppm dan daun pandan wangi 39,7% Penelitian ini bertujuan untuk mengetahui aktivitas kombinasi ekstrak etanol daun pandan wangi dan kayu manis dalam menurunkan kadar MDA. tikus yang diinduksi parasetamol. Penelitian menggunakan metode eksperimental, dilakukan selama 9 hari dengan 30 ekor tikus jantan dibagi menjadi 6 Kelompok, yaitu: Normal diberi aquadest, Kontrol Positif diberi silimarin 100 mg/kgBB, Kontrol Negatif diberi CMC-Na 0,05%, serta 3 kelompok lainnya diberi kombinasi ekstrak daun pandan wangi:kayu manis berturut-turut dosis I (25:75), dosis II (50:50), dosis III (75:25). Semua kelompok diinduksi parasetamol 2,5 g/kgBB pada hari ke-7 setelah 30 menit perlakuan, kecuali kelompok normal. Pada hari ke 9 dilakukan pengukuran kadar MDA dengan metode TBARs menggunakan spektrofotometri. Pemberian kombinasi ekstrak etanol daun pandan wangi dan kayu manis dapat menurunkan kadar MDA dengan kombinasi dosis yang paling optimal adalah 75:25 berdasarkan statistik dengan nilai signifikan 0,000<0,05 dibandingkan dengan kelompok negatif. Cases of liver disease have increased with the use of hepatotoxin compounds, one of which is due to the use of paracetamol with excessive doses. This can increase the production of free radicals so that it triggers oxidative stress which can cause tissue damage which is characterized by increased levels of Malondialdehyde (MDA). Oxidative stress can be overcome with antioxidants from various plants. Cinnamomum burmanii has antioxidant activity with IC50 value of 53ppm and Pandanus amarrylifolius 39.7%. This study aims to determine the combined activity of ethanol extract of Pandanus amarrylifolius and Cinnamomum burmanii in reducing MDA levels. Paracetamol-induced rats. Research using experimental methods, conducted for 9 days with 30 male rats divided into 6 groups, namely: Normal given aquadest, Positive Control were given silimarin 100 mg / kgBB, Negative Control was given CMC-Na 0.05%, and 3 other groups were given a combination of Pandanus amarrylifolius extract: Cinnamomum burmanii dose I (25:75), dose II (50:50), dose III (75:25). All groups induced paracetamol 2.5 g / kgBB on the 7th day after 30 minutes of treatment, except the normal group. On the 9th day MDA levels were measured using the TBARs method using spectrophotometry. Giving a combination of Pandanus amarrylifolius and Cinnamomum burmanii ethanol extract can reduce MDA levels with the most optimal dose combination is 75:25 based on statistics with a significant value of 0,000<0.05 compared with the negative group.

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