scholarly journals The Influence of β-1,3-1,6-Glucans on Rabies Vaccination Titers in Cats

2020 ◽  
Vol 7 (3) ◽  
pp. 118
Author(s):  
John Byrne ◽  
Darryn Knobel ◽  
Susan M. Moore ◽  
Stephanie Gatrell ◽  
Patrick Butaye

β-glucans have been shown to stimulate the immune system in several animal species. The aim of this study was to evaluate the immune stimulation capacity of a fully formulated diet with β-1,3-1,6-glucans in cats, by assessing the rabies antibody titer after vaccination. Thirty-five healthy cats were recruited. The cats were placed into two groups and fed a standard diet in accordance with body weight. One group had the β-glucans incorporated into the diet; the other group served as the control group. After two weeks of dietary adjustment; the rabies vaccine (Imrab® 3 TF; Merial) was administered on days 0 and 21. Blood samples were taken on days 0, 21, and 42. Titers were determined with the rapid fluorescent foci inhibition test (RFFIT). Titers at days 21 and 42 were compared between the two groups in a linear mixed effects model. This study showed that the animals receiving the non-supplemented feed had higher post-vaccination rabies antibody titers. This indicates that, in contrast to other animal species, the β-glucan supplemented diet did not have the expected positive effect on the rabies antibody titers in cats.

Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2238
Author(s):  
Denise Innosa ◽  
Andrea Ianni ◽  
Michele Faccia ◽  
Camillo Martino ◽  
Lisa Grotta ◽  
...  

The aim of this study is to evaluate the physical, nutritional, and sensory properties of cheese obtained from goats fed a dietary supplementation with olive leaves (OL). Thirty Saanen goats were randomly allocated into two groups of 15 goats each, (1) a control group fed with a standard diet (CG), and (2) an experimental group (EG) fed an OL-enriched diet. The trial lasted for 30 days. The milk of each group was then collected and used to produce Caciotta cheese, which was analyzed at the beginning and at the end of the ripening period (60 days). The results showed a positive effect of dietary OL supplementation in improving the fatty acid profiles due to the significant increase of unsaturated fatty acids, mostly α-linolenic acid (C18:3 n-3), with the consequent reduction of the ω-6/ω-3 ratio, a condition commonly associated with an increased health functionality of food products. Moreover, improved oxidative stability was observed in cheese during ripening, a presumable consequence of the transfer into the milk of dietary bioactive compounds, mainly polyphenols of high biological value, and credited as a marked antioxidant potential. Furthermore, reduced lipolytic action was observed in 60-day ripened cheese, even if no significant changes in sensory properties were evidenced.


2021 ◽  
Vol 37 ◽  
pp. 00143
Author(s):  
Irina Funk ◽  
Nikolay Vladimirov ◽  
Alexander Yashkin ◽  
Lyudmila Pautova ◽  
Vitaly Gorshkov

The work aims to study the effect of different doses of the experimental probiotic preparation “Plantarum” when fed to pregnant animals on their reproductive qualities, as well as on the growth and development of young animals. To obtain young animals, four groups of goats were formed in the type of the Saanen breed, 20 heads each. In the first (control) group, the animals received a standard diet, in the diet of the animals of the second, third and fourth groups in the second half of pregnancy, the probiotic preparation “Plantarum” was additionally introduced, containing Lactobacillus Plantarum, Propiobacterium freudenreihii, in dosages from 0.4 to 0.8 ml/kg of body weight per day. From the offspring of the goats of the experimental groups, four groups of 12 goats were formed. The highest percentage of preservation (94%) and the highest business output of kids per 100 queens (150%) were observed in the fourth experimental group (0.8 ml). The goats of the second, third and fourth groups exceeded the body weight of their contemporaries from the control group by 3%, 6.3%, and 8.8%. The highest indices of the absolute increase in body weight by age periods were noted in the fourth group of goats. There were no significant differences in body build indices during the experiment between the goats of the control and experimental groups. Thus, the maximum positive effect was observed with the introduction of a probiotic preparation into the diet of pregnant goats at a dose of 0.8 ml/kg of body weight per day.


2021 ◽  
Vol 1 (5) ◽  
pp. 57-62
Author(s):  
R. F. Ivannikova ◽  
◽  
N. V. Pimenov ◽  

The article presents the results of studies on the use of synbiotic feed additives based on live spore-forming bacteria of the genus Bacillus, lysates of lactic acid bacteria and yeast to lambs of 10-day-old Volgograd breed in various doses. The use of the feed additive did not have a negative effect on the morphological parameters of the lambs ' blood. Physiological parameters for the entire observation period were within the reference values characteristic of this animal species. The positive effect of synbiotic feed additive was manifested by higher growth rates – an increase in the live weight of the lambs of the experimental groups compared to the control group.


2021 ◽  
Vol 3 (1) ◽  
pp. 1-4
Author(s):  
Getas I Wayan ◽  
Danuyanti I Gusti Ayu Nyoman ◽  
Yuniarni Annisa

The occurrence of human rabies in Indonesia approximately amounted to 168 cases. The countermeasures taken were vaccination, quick treatment for individuals, KIE (Komunikasi, Informasi, dan Edukasi; Communication, Information, and Education), surveillance, selective dog elimination and post-exposure management. Vaccination was one of the effective countermeasures against the distribution of rabies. It might be conducted either before or after the virus exposure. Despite its effectiveness, it could end in failure due to several factors, one of which was the nutritional status of patient. However, the failure could be overcome by enhancing the immune system (immunostimulator) with the administration of wild horse milk. The milk contained lactoferrin known as protein inducing antibody. Sample consisted of 15 rabbits. They were divided into three groups. Each group consisted of five rabbits. Group t1 for titer testing in immunoglobulin after anti-rabies vaccination; while Group t2 and t0 for titer testing in immunoglobulin after rabies-vaccination and administration of wild horse milk and for the control group without any treatment respectively. The results showed a titer increase in Ig G after vaccination by 40% in Group t2 and t2 (p>0.05). Besides, the administration of wild horse milk could increase titer in IgG after vaccination for two weeks (p<0.05). In Conclusion, Administration of wild horse milk could increase titer in IgG after vaccination.


2019 ◽  
pp. 33-37
Author(s):  
M.A. Verotchenko

Цель исследования изучение биохимического статуса организма телят 1 3месячного возраста при применении вермикулита. Опыт на животных проводили в течение 60 дней. Для опыта были отобраны, по принципу аналогов, 3 группы телят молочного периода выращивания по 9 голов в каждой. Телята контрольной группы получали стандартный рацион, телятам 1й опытной группы к основному рациону добавляли 2 на голову в сутки вермикулита, 2й опытной группе 3 на голову в сутки. Использовали вермикулит (ГОСТ 1286567), выпускаемый ОАО Ковдорслюда . Для изучения состояния обменных процессов в организме подопытных животных отбирали кровь из яремной вены после утреннего кормления два раза: в начале опыта и через месяц после его окончания. Исследования показали, что использование вермикулита в кормлении молочных телят, благодаря многогранным буферным, ионообменным и сорбционным свойствам положительно сказалось на белковоминеральном обмене животных и интенсивности их роста. В опытных группах уровень общего белка вырос в 1,04 1,06 раза, достоверно повысился к концу исследований уровень альбуминов. Целесообразно для нормализации обменных процессов в организме молочных телят использовать добавку вермикулита в количестве 2 и 3 к сухому веществу рациона.The purpose of the research is to study the biochemical status of the organism of calves 13 months of age with the use of vermiculite. The animal experiment was carried out for 60 days. 3 groups of calves of the dairy period of growing of 9 animals in each were selected for the experiment according to the principle of analogues. The calves of the control group received a standard diet, 2 per head per day of vermiculite was added to the main diet of the calves of the 1st experimental group, and the 2nd experimental group 3 per head per day. We used vermiculite (GOST 1286567) manufactured by OAO Kovdorslyuda. To study the state of metabolic processes in the body of experimental animals blood was taken from the jugular vein after morning feeding two times: at the beginning of the experiment and one month after its completion. Researches have shown that the use of vermiculite in the feeding of dairy calves due to its multifaceted buffering, ionexchange and sorption properties has a positive effect on the proteinmineral metabolism of animals and their growth rate. In the experimental groups the level of total protein increased in 1.04 1.06 times and the level of albumen significantly increased by the end of the research. It is advisable to normalize the metabolic processes in the body of dairy calves to use the additive of vermiculite in an amount of 2 and 3 to the dry matter of the diet.


2018 ◽  
pp. 1637-1640
Author(s):  
Gusti Ayu Yuniati Kencana ◽  
Nyoman Suartha ◽  
I Made Kardena ◽  
Gusti Ayu Mayani Kristina Dewi ◽  
Arini Nurhandayani ◽  
...  

Aim: The study was aimed to prepare and examine the potential and safety concerns of egg drop syndrome (EDS) vaccine candidate seed. The potential and safety trials of EDS Medan isolate vaccine need to be done before commercial scale of EDS vaccines are made. Materials and Methods: The safety test of EDS candidate vaccine was tested on 4-week-old specified pathogen-free chickens in an experimentally isolated enclosure. Results: The result of the safety test obtained 27.3 hemagglutination inhibition (HI) unit of geometric mean titer antibody post-vaccination. However, the potency test of the EDS candidate vaccine was conducted on 17-week-old laying hens. Test results of the EDS potency vaccine in layer obtained antibody titer increased in every week of blood taking with average titer of antibody: Before vaccinated was 22.9 HI unit, 1 week after vaccination was 23.7 HI unit, 2 weeks post-vaccination was 25 HI unit, and 3 weeks after vaccination was 27.3 HI units. In contrast, decreasing trend was observed in control group (unvaccinated chicken). Conclusion: Serologically, the seed vaccine of EDS virus isolates from Medan was able to produce protective antibody titers starting in the 2nd and 3rd weeks post-vaccination.


Author(s):  
E. L. Kuznetsova ◽  
L. A. Dultsev ◽  
E. V. Safin

Goal of research - the study aims to examine the osteopathic profi le of children with dysarthria and to develop recommendations for osteopathic correction of somatic dysfunctions in 2-3 year old children presenting this pathology.Materials and methods. 30 2-3 year old children with the symptoms of dysarthria took part in the research. All the children were divided into 2 groups: the control group of 15 children received standard treatment, and the experimental group of 15 children received both standard and osteopathic treatment. The dysarthria severity and the osteopathic profi le were evaluated with account of the number of somatic dysfunctions at global, regional, and local levels.Results. The osteopathic correction was shown to have a positive effect on dysarthria severity. The study established a correlation between the dysarthria severity in children and the number of somatic dysfunctions at the local level.Conclusion. The study suggests using osteopathic correction of somatic dysfunctions in the complex therapy of dysarthria in children.


2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.


2020 ◽  
Vol 4 (1) ◽  
pp. 62-95
Author(s):  
Daniele Artoni ◽  
Valentina Benigni ◽  
Elena Nuzzo

Over the last three decades, a growing number of studies have investigated the effects of instruction on the acquisition of pragmatic features in L2. The bulk of this research has focused mainly on the teaching of English as a second/foreign language. However, instructional pragmatic studies in L2-Russian are lacking. The main purpose of our study is to contribute towards filling this gap by analysing the effects of pragmatic instruction on the acquisition of two speech acts by Italian learners of Russian. Furthermore, we aim to explore whether the Multimodal Russian Corpus (MURCO), a multimedia subcorpus of the Russian National Corpus, can be an effective tool for teaching speech acts in L2-Russian. Our research was composed of one experimental group (n = 18) and one control group (n = 11); each was composed of two intact classes of Italian university students at an intermediate level of L2-Russian, who were pre- and post-tested using a written discourse completion task. The experimental group was subjected to a programme of pragmatic instruction – eight thirty-minute MURCO-based lessons devoted to requests and advice, while the control group was taught according to the standard syllabus, that is, with no pragmatic instruction. The results revealed that the use of the target pragmatic features varied significantly in the experimental group, but not in the control group, thus showing a general positive effect of the instructional treatment based on the MURCO corpus. However, some limitations were identified with regard to the usability of this tool by teachers and learners.


2020 ◽  
Vol 19 (2) ◽  
pp. 217-221
Author(s):  
Maria Jesús Lisbona-González ◽  
Candela Reyes-Botella ◽  
Esther Muñoz-Soto ◽  
Maria Victoria Olmedo-Gaya, ◽  
Jorge Moreno-Fernandez ◽  
...  

Adipose tissue is an endocrine organ and has central role in interaction with other organs or tissues while propolis can induce lipolysis. Therefore, the aim of this study is to provide detailed information about adipose tissue homeostasis modifications and body composition during propolis supplement consumption. Twenty male Wistar albino rats (8 weeks) were divided into two groups of 10 animals each and fed for 90 days with two different types of diets: standard for the control group (diet C) and standard diet + 2% propolis (diet P). Thyroid hormones did not show differences, while ghrelin and adiponectin decreased in the group that was fed propolis. Insulin, leptin, and non-esterified fatty acids also increased along with reduced body weight and fat, in addition to increased lean mass when propolis was in the diet. We conclude that propolis could decrease ghrelin and adiponectin but increase non-esterified fatty acids and insulin secretion, which improves body composition.


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