scholarly journals Emotional Processing In Patients with Ischemic Heart Diseases

2018 ◽  
Vol 6 (9) ◽  
pp. 1627-1632
Author(s):  
Shirali Kharamin ◽  
Mohammad Malekzadeh ◽  
Arash Aria ◽  
Hamide Ashraf ◽  
Hamid Reza Ghafarian Shirazi
Keyword(s):  
Cardiovascular Disease ◽  
Emotional Processing ◽  
Heart Diseases ◽  
Public Health Problem ◽  
Ischemic Heart ◽  
Control Group ◽  
Stress Appraisal ◽  
Processing Styles ◽  
Significant Difference ◽  
Key Factor

BACKGROUND: Cardiovascular disease is the most prevalent public health problem on a worldwide scale, and ischemic heart disease accounts for approximately one-half of these events in high-income countries. One of the most important risk factors for this disease is mental and psychological especially stressful experiences. AIM: This research was established to compare emotional processing, as a key factor in stress appraisal, between IHD patients and people with no cardiovascular disease. METHODS: Using simple sampling, fifty patients were selected from people who diagnosed as IHD in the hospital and referred for treatment after discharging care and treatment. Control group participants were selected as control group peoples, using neighbourhood controls selection. The Emotional Processing Scale was filled by all members of the two groups. RESULTS: There were significant differences between the two groups on the EPS-25 total scores, as well as on emotional processing dimensions of signs of unprocessed emotion, unregulated emotion; avoidance and impoverished. Also, there was no significant difference between the two groups in the dimension of Suppression. The final step of regression revealed a β of 10.15 and 1.05 for AVO and IEE subscales respectively. CONCLUSION: The result showed that patients with IHD are using more negative emotional processing styles.

Homeopathy: statistical significance versus the sample size in experiments with Toxoplasma gondii

2021 ◽  
Vol 10 (36) ◽  
pp. 115-118
Author(s):  
Érika Cristina Ferreira ◽  
Paula Fernanda Massini ◽  
Caroline Felicio Braga ◽  
Ricardo Nascimento Drozino ◽  
Neide Martins Moreira ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Sample Size ◽  
Biological Effects ◽  
Statistical Significance ◽  
Rare Event ◽  
Public Health Problem ◽  
Control Group ◽  
Bootstrap Analysis ◽  
Significant Difference ◽  
The World

Introduction: Toxoplasmosis is a zoonosis that represents a serious public health problem, caused by Toxoplasma gondii, which affects 20-90% of the world human population [1,2]. It is a serious problem especially when considering the congenital transmission due to congenital sequels. Treatment with highly diluted substances is one of the alternative/complementary medicines most employed in the world [3,4]. The current ethical rules regarding the number of animals used in animal experimental protocols with the use of more conservative statistical methods [5] can not enhance the biological effects of highly diluted substances observed by the experience of the researcher. Aim: To evaluate the minimum number of animals per group to achieve a significant difference among the groups of animals treated with biotherapic T. gondii and infected with the protozoan regarding the number of cysts observed in the brain. Material and methods: A blind randomized controlled trial was performed using eleven Swiss male mice, aged 57 days, divided into two groups: BIOT-200DH - treated with biotherapic (n=6) and CONTROL - treated with hydroalcoholic solution 7% (n=7).The animals of the group BIOT-200DH were treated for 3 consecutive days in a single dose 0.1ml/dose/day. The animals of BIOT – 200DH group were orally infected with 20 cysts of ME49-T. gondii. The animals of the control group were treated with cereal alcohol 7% (n=7) for 3 consecutive days and then were infected with 20 cysts of ME49 -T. gondii orally. The biotherapic 200DH T. gondii was prepared with homogenized mouse brain, with 20 cysts of T. gondii / 100μL according to the Brazilian Homeopathic Pharmacopoeia [6] in laminar flow. After 60 days post-infection the animals were killed in a chamber saturated with halothane, the brains were homogenized and resuspended in 1 ml of saline solution. Cysts were counted in 25 ml of this suspension, covered with a 24x24 mm coverglass, examined in its full length. This study was approved by the Ethics Committee for animal experimentation of the UEM - Protocol 036/2009. The data were compared using the tests Mann Whitney and Bootstrap [7] with the statistical software BioStat 5.0. Results and discussion: There was no significant difference when analyzed with the Mann-Whitney, even multiplying the "n" ten times (p=0.0618). The number of cysts observed in BIOT 200DH group was 4.5 ± 3.3 and 12.8 ± 9.7 in the CONTROL group. Table 1 shows the results obtained using the bootstrap analysis for each data changed from 2n until 2n+5, and their respective p-values. With the inclusion of more elements in the different groups, tested one by one, randomly, increasing gradually the samples, we observed the sample size needed to statistically confirm the results seen experimentally. Using 17 mice in group BIOT 200DH and 19 in the CONTROL group we have already observed statistical significance. This result suggests that experiments involving highly diluted substances and infection of mice with T. gondii should work with experimental groups with 17 animals at least. Despite the current and relevant ethical discussions about the number of animals used for experimental procedures the number of animals involved in each experiment must meet the characteristics of each item to be studied. In the case of experiments involving highly diluted substances, experimental animal models are still rudimentary and the biological effects observed appear to be also individualized, as described in literature for homeopathy [8]. The fact that the statistical significance was achieved by increasing the sample observed in this trial, tell us about a rare event, with a strong individual behavior, difficult to demonstrate in a result set, treated simply with a comparison of means or medians. Conclusion: Bootstrap seems to be an interesting methodology for the analysis of data obtained from experiments with highly diluted substances. Experiments involving highly diluted substances and infection of mice with T. gondii should be better work with experimental groups using 17 animals at least.

scholarly journals The Effect of Educational Intervention on Efficacy of 1% Permethrin Shampoo and 4% Dimeticone Lotion to Treat Head Lice Infestation Using Propensity Score Matching (PSM)

2021 ◽  
Author(s):  
Eslam Moradi Asl ◽  
Abedin Saghafipour ◽  
Amir Hamta ◽  
Zahra Taheri-Kharameh ◽  
Malek Abazari ◽  
...  
Keyword(s):  
Successful Treatment ◽  
Intervention Group ◽  
Public Health Problem ◽  
Estimating Equation ◽  
Control Group ◽  
Head Lice ◽  
Significant Difference ◽  
Quasi Experimental ◽  
East Azerbaijan ◽  
Head Lice Infestation

Abstract Background Head lice are a main public health problem and the most important human ectoparasites and the use of pediculicides is the most common way to control it. One of the possible causes of treatment failure is the lack of improper application of pediculicide. The aim of this study was to assess the effect of education on efficacy of 1% permethrin or 4% dimeticone lotion to treat head lice infestation. Methods This quasi-experimental study was performed on 100 people infected with head lice in comprehensive urban health centers of Ardabil (intervention group) and 400 people of East Azerbaijan and West Azerbaijan (control group) provinces from April to March 2019. The data collection tool included demographic questionnaire and examination evidence recording sheet in terms of presence of hits or adult lice. Results The outcome of treatment included elimination of head lice infestation on days 7, and in the case of recurrence, it was considered on days 14 and 30 after treatment. Data were analyzed using R software and Generalized Estimating Equation method. GEE analysis showed there is significant difference in evaluating head lice over time. Conclusion Participants who received the training intervention (OR = 3.29; CI 95%: 2.21–4.88) were more likely to have a successful treatment than control group. In the case of providing proper training on the use of pediculicides and observing hygiene tips to patients with pediculosis, could help to successful treatment of pediculosis.

scholarly journals STUDI KOMPARASI: EFEKTIFITAS PSIKOEDUKASI TERHADAP ADAPTASI PASIEN FRAKTUR DI RSUD JOMBANG

2018 ◽  
Vol 1 (2) ◽  
pp. 74-80
Author(s):  
Zuhrotul Umaroh ◽  
Elsye Maria Rosa
Keyword(s):  
Intervention Group ◽  
Public Health Problem ◽  
Test Sample ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Major Public Health Problem ◽  
Control Group Design ◽  
Significant Difference ◽  
Before And After

Background: The injury is still a major public health problem throughout the country, where two-thirds occur in developing countries, including Indonesia. In Indonesia, recorded injury cases in 2013 reached 84,277 people (8.2%). The negative impacts caused by the fracture appears, which includes; psychological, social, and spiritual. The Department of Health reported that 15% of patients experiencing psychological stress fractures to depression. Psychoeducation efficient in the treatment process and decrease the symptoms of depression that is a component in the psychological response on the existence of a disability condition. Aim: the research aimed todetermine the effectiveness of psychoeducation to the physical adaptation among fracture patients in public hospital of Jombang Method: this is a quasi-experiment research with pre-test and post-test control group design. There were 16 respondents in control group and another 16 respondents for intervention group which was gathered with consecutive sampling. The data were analyzed with parametric analysis using paired sample t-test dan independent t-test. For testing the data normality distribution, Shapiro-wilk analysis was operated. Result: Paired t test sample stated that there was significant difference in the physical adaptation among fracture patients before and after the intervention of psychoeducation (p value = 0,000 ; CI 95% <alpha = 0,05). In the unpaired t test was obtained p value = 0.000; CI 95% <alpha = 0.05, which indicates a significant difference of fracture patients’ adaptation who has given psychoeducation intervention and who has not. Conclusion: the psychoeducation intervention  increasedphysical adaptation among fracture patients. Nurses must continue to develop and apply the procedures for implementing psychoeducation fractures primarily in patients with the aim to improve the adaptability of fracture patients.

scholarly journals The impact of using BASNEF model on self-control behaviors among Patients with hypertension

2018 ◽  
Vol 3 (3) ◽  
pp. 112
Author(s):  
Moradali Zareipour ◽  
Mousa Ghelichi Ghojogh ◽  
Masoumeh Mahdi-akhgar ◽  
Sarvin Abbasi ◽  
Nooshin Yoshany ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Intervention Group ◽  
Public Health Problem ◽  
Developed Countries ◽  
Self Control ◽  
Control Group ◽  
Validity And Reliability ◽  
Important Public Health Problem ◽  
Significant Difference ◽  
The Impact

Background: High blood pressure is the most important public health problem in developed countries. It is one reason for early mortality and risk factors for cardiovascular diseases like stroke and kidney failure. This study aimed to determine the effect of educational intervention based on BASNEF in blood pressure control in 1395.Methods and Materials: This study was a quasi-experimental study on 160 patients in two groups (each n = 80) suffering from hypertension in urban health centers of Urmia. Data collection questionnaire included: demographic questions, knowledge base questions, self-control behaviors questions and structures of  BASNEF model. Validity and reliability were respectively 80% and 79%. Intervention group had taken three 45 minutes sessions using speeches, questions and answers, posters, booklets, pamphlets and whiteboard. Before training, information collected through questionnaires and after training questionnaires were completed again after 3 months. The data were analyzed in SPSS software with chi-square tests, Fisher, independent and paired sample t-test.Results: The average age of case and control group were  99.11 ± 01.56 and 75.12 ± 66.53 years. That there was no statistically significant difference (p=0.1). After intervention average systolic blood pressure significantly decreased in the intervention group from 43.157 to 24.147 mm Hg and diastolic blood pressure significantly decreased from 21.93 to 52.87 mm Hg (P <0.05)Conclusion:  The training program using BASNEF model has provided better results in controlling blood pressure than conventional trainings.

scholarly journals Myonecrosis in Aortic Valvular Heart Diseases

2009 ◽  
Vol 13 (Number 2) ◽  
pp. 9-12
Author(s):  
Md. Khalequzzaman ◽  
M A Islam ◽  
Md. O Hoque ◽  
M Ferdous ◽  
A H K Chowdhury ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Left Ventricular ◽  
Definitive Treatment ◽  
Control Group ◽  
Cross Sectional ◽  
Valvular Heart Diseases ◽  
Significant Difference ◽  
Venous Sample

This cross sectional study was done among 20 patients with aortic stenosis and 20 healthy controls to evaluate the association of cardiac specific troponin 1 (ant) and sonic valvular heart diseases. The study was conducted in °militant, department in National laminae of Cardiovascular Diseases (N1CVD.)A structured queslionilaire and checklist was used to collect data through face to face interview. Color dapple, echocarchiognsphy was done and 5 ml of venous sample was dmwo from each subjects and laboratory estimation of an, was done. The arid in control group and sonic stenosis patients showed significant difference in mean (<0.001). ant level in aortic stenosis patients increases in the absence of heart failure indicating that it can expose the cardiotnyocnes to injury prior to development of oven left ventricular dysftinction. So. serial monitoring of aid may help clinicians to give definitive treatment (reface development af complications.

scholarly journals COMPARISON OF THE EFFECTIVENESS OF PHYSICAL TRAINING AND EXTRACT OF SOURSOP LEAF TO HISTOPATHOLOGY OF ABDOMINAL AORTA FOAM CELLS IN HIPERCOLESTEROLEMIA-DIABETES RAT

2020 ◽  
Vol 3 (1) ◽  
pp. 37-50
Author(s):  
Tika Hamidah Apriliana Nai ◽  
Retno Yulianti ◽  
Wahyunia Likhayati Septiana ◽  
Yuni Setyaningsih
Keyword(s):  
Diabetes Mellitus ◽  
Physical Training ◽  
Public Health Problem ◽  
Foam Cells ◽  
Atherogenic Diet ◽  
Control Group ◽  
Standard Diet ◽  
Control Group Design ◽  
Significant Difference ◽  
Post Test

Background: Diabetes mellitus has become a public health problem globally. Type 2 diabetes mellitus, caused by lifestyle and high lipid diet, is the most common form. Hypercholesterolemia-diabetes is able to create endothelial injury that results in formation of atherosclerosis, starting with formation of foam cells. Objective: This research aimed to see the effectiveness of physical training and soursop (Annona muricata) leaves extract in lowering the amount of foam cells.Methods: This research was an experimental study which used the post test-only control group design with 35 Wistar strain rats which were randomly divided into 7 groups, each consisting of 5 rats. K1 was given standard diet, K2 was given atherogenic diet and alloxan, while K3, K4, K5, K6, and K7 were given atherogenic diet, alloxan, and different treatments based on designed group. K3 was given simvastatin, K4 was given metformin, K5 was given physical training, K6 was given soursop leaves extract (SLE), and K7 was given both physical training and SLE. The rats were euthanized after three weeks and aorta was taken to be made into histology slides for foam cells observation.Results: The result of Kruskal-Wallis and Mann-Whitney Post-Hoc Test showed significant difference (p<0,05) between K2 and K5, K6, K7 while it no significant difference (p>0,05) between K3, K4 and K5, K6, K7.Conclusion: Physical training, SLE, and the combination of both have a role in lowering formation of foam cells in atherosclerosis.

138 LIVER RECEPTOR HOMOLOG 1 INFLUENCES BLASTOCYST HATCHING IN PORCINE

2016 ◽  
Vol 28 (2) ◽  
pp. 199
Author(s):  
J. Guo ◽  
T. Kim ◽  
N.-H. Kim ◽  
X.-S. Cui
Keyword(s):  
Messenger Rna ◽  
Mrna Level ◽  
Embryonic Stem ◽  
Control Group ◽  
Hatching Rate ◽  
Orphan Nuclear Receptor ◽  
Treatment Groups ◽  
Oct4 Expression ◽  
Significant Difference ◽  
Key Factor

Liver receptor homolog 1 (LRH1, NR5A2) belongs to the orphan nuclear receptor superfamily and has diverse functions in development, differentiation, metabolism, and cell death. The LRH1 gene is expressed in embryonic stem cells and regulates the expression of OCT4, which is the key factor required to maintain pluripotency. However, the function of LRH1 in early porcine embryo development is still unknown. In the present study, we examined the localization and mRNA level of LRH1 in porcine parthenotes by immunofluorescence and real-time RT-qPCR. To explore the function of LRH1, the embryos were treated with the specific antagonist of LRH1, 505601, which is a cell-permeable pyrazolylbiphenylethanone compound that targets LRH-1/NR5A2 ligand binding domain (LBD) via direct affinity interaction, preventing LRH-1 from assuming an active conformation. Every group contained 20 embryos. The results showed that the immunofluorescence signal of LRH1 was only observed in nuclei of blastocyst cells. Inhibition of LRH1 by antagonist significantly (P < 0.05) reduced the blastocyst rate in the 50 µM (37.30 ± 3.67%) and 100 µM (38.02 ± 5.12%) treatment groups compared with the control group (53.43 ± 3.67%). The hatching rate of blastocysts was also reduced (P < 0.01) by 50 µM (12.66 ± 3.13%) and 100 µM (20.10 ± 2.81%) antagonist compared with control (40.59 ± 0.59%), which resulted from the decreased (P < 0.05) expression of hatching-related genes, such as FN1, ITGA5, and COX2. Inhibition of LRH1 also increased (P < 0.05) the number of apoptotic cells in blastocysts. Moreover, inhibition enhanced expression of apoptotic genes, BAX and CASP3, and reduced the anti-apoptosis gene BCL2 (P < 0.05). Messenger RNA and protein level of OCT4 were sharply decreased in blastocysts after LRH1 inhibition. All data were analysed with a one-way ANOVA, and differences between treatment groups were assessed by the least significant difference (LSD) test using SPSS software (SPSS Inc., Chicago, IL, USA). In conclusion, LRH1 affects blastocyst formation and hatching by regulating OCT4 expression and cell apoptosis.

scholarly journals EFFECTIVENESS OF DIABETIC FOOT EXERCISES USING SPONGES AND NEWSPAPERS ON FOOT SENSITIVITY IN PATIENTS WITH DIABETES MELLITUS

2019 ◽  
Vol 5 (6) ◽  
pp. 234-238
Author(s):  
Siti Fadlilah ◽  
Adi Sucipto ◽  
Nazwar Hamdani Rahil
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Community Health Centers ◽  
Public Health Problem ◽  
Sampling Technique ◽  
Total Sample ◽  
Control Group ◽  
Significant Difference ◽  
Patients With Diabetes

Background: Diabetes mellitus is a critical public health problem, and its prevalence in Indonesia remains high. Diabetes mellitus may cause complications, one of which is neuropathy that can impair foot sensitivity. This requires a treatment by doing diabetic foot exercises using sponges and paper.Objective: To examine the effectiveness of diabetic foot exercise using sponges and newspapers on foot sensitivity in patients with diabetes mellitus.Methods: This is a quasi-experimental study with pretest posttest with a control group research design, which was conducted at Public Health Center Depok III, Sleman Regency, Yogyakarta, Indonesia. An accidental sampling technique was used to select participants, with a total sample of 108 respondents consisting of 36 respondents in a control group, 36 respondents in a sponge group, and 36 respondents in a newspaper group. Data were analyzed using Wilcoxon and Mann-Whitney test.Results: Among the three groups, only those who received foot exercises using sponges and newspapers had a significant effect on foot sensitivity (p <.05). However, there was no significant difference on the effect of foot exercise on foot sensitivity between sponges and newspapers group (p >.05).Conclusion: The use of sponges and newspapers in foot exercise could significantly improve foot sensitivity in patients with type 2 diabetes mellitus. It is therefore recommended for nurses to provide the foot exercise as a part of nursing practice in both hospitals and community health centers.

scholarly journals Tera Gymnastic Effective For Patient With Hypertension

2019 ◽  
Vol 7 (3) ◽  
Author(s):  
Hesti Platini ◽  
Sandra Pebrianti ◽  
Indra Maulana
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Intervention Group ◽  
Management Plan ◽  
Control Group ◽  
Body Parts ◽  
Blood Pressure Targets ◽  
Significant Difference ◽  
Before And After

Hypertension is a cardiovascular disease globally. Hypertension is remains silent killer, the clinical strategy to focusing on new and improved treatments is exercise. Tera  gymnastics is a physical and mental exercise, combining the movement of body parts with breathing techniques and rhythms through the concentration of thought that is carried out regularly, harmoniously, correctly and continuously, Physical activity can reduce high blood pressure. Some study showed Regular physical activity is an effective intervention with respect to these factor, decreasing mortality rate for cardiovascular disease and all cause of disease in hypertensive patient. Gymnastic Tera exercise can help to control metabolic variable related to hypertension. The study was use quasy experimental design with one group pretest-posttest. The study was conducted in Puskesmas Pasundan Garut. Sampling in this study is subjects  that is criteria patients has hipertension with 8 weeks treatment so will take methode of  concecutive sampling with 15 respondents for intervention group and 15 for control group.  The sample were age 30-55 years. The Intervention was gymnastic tera exercise. The Blood pressure function was evaluated before and after the training period. The data were analyzed by using t-test paired. The result showed a significant difference before and after tera gymnastic exercise in patient with hypertension I (p=000.0). Result of systolic blood presure when in mean SD pretest is 146.00 higher than post test is 136.00 in intervention group. The tera gymnastic exercise conditioning program achieved effect in this population. The reduction of blood pressure after exercise is of great clinical relevance.  The increased riskof physical inactivity in controlling hypertension in our study suggest that general practitioners must be in the habit of prescribing practice of physical exercise. Physical activity has been shown to have beneficial effect on blood pressure. patients are followed up regularly to confirm that they are adhering to the management plan and the blood pressure targets.

scholarly journals EFFECTIVENESS OF CARDIAC HEALTH AWARENESS PROGRAM ON PRACTICES REGARDING PREVENTION OF CARDIOVASCULAR DISEASE (CVD) AMONG PREMENOPAUSAL WOMEN IN SELECTED AREAS OF BENGALURU

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Mr. Ummed Ram ram ◽  
Dr. Darling B. Bibiana bibiana
Keyword(s):  
Cardiovascular Disease ◽  
Premenopausal Women ◽  
Control Group ◽  
Health Awareness ◽  
Cardiac Health ◽  
Awareness Program ◽  
Significant Difference ◽  
And Control ◽  
Experimental Group ◽  
Prevention Of Cardiovascular Disease

This study was aimed to assess effectiveness of cardiac health awareness program on practices regarding prevention of cardiovascular disease (CVD) among premenopausal women in selected areas of Bengaluru. Methodology: Quasi experimental pretest posttest control group design was used. Non-probability purposive sampling technique to select 100 in each experimental and control group who met the inclusion and exclusion criteria. Pre-test was administered using self-reported checklist for control and experimental group. Cardiac health awareness program was administered to the experimental group. After seven days and three months of administration of Cardiac health awareness program post-test was conducted using the same self-reported checklist for both groups. Results: The findings of the study revealed that regarding pretest among experimental group during pretest 51 had poor level of practice, 49 had average level of practice and none had good level of knowledge on practice which was improved after intervention with majority posttest I and posttest II with majority 71 and 72 of the subjects had average level of practice, 29 and 25 has good level of practice and none in posttest I and 3 in posttest II had poor level of practice respectively. Among control group during pretest almost 54 had poor level of practices and there was no improvement found in posttest I and II. Calculated F value within experimental group was 131.985 whereas within control group was 1.2384. Unpaired t test between experimental and control group showed significant difference with t value 11.62 (p<0.0001) and 11.01 (p<0.0001) in posttestI and posttest II respectively revealing that there was significant difference between experimental group and control group. Thus, it proves that Cardiac health awareness program was effective. Conclusion: Cardiac health awareness program was effective in improving the practices among premenopausal women.

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