scholarly journals Influence of the probiotic preparation Immunoflor on the physiological status of a young chicken of a productive herd of egg cross

2021 ◽  
Vol 935 (1) ◽  
pp. 012043
Author(s):  
V G Semenov ◽  
V V Boronin ◽  
N I Kosyaev ◽  
S S Kozak ◽  
N G Ivanov ◽  
...  
Keyword(s):  
Physiological State ◽  
Research Work ◽  
Hemoglobin Concentration ◽  
The Body ◽  
Physiological Status ◽  
Nonspecific Resistance ◽  
Humoral Factors ◽  
Probiotic Preparation ◽  
Young Chicken ◽  
Stimulation Of

Abstract The article presents the results of studies of the effectiveness of the use of the complex probiotic preparation Immunoflor in young hens of egg cross. In the course of the research work, it was found that the use of the probiotic preparation Immunoflor does not affect the clinical and physiological state of the body of young chickens, but at the same time reduces the incidence, mortality and increases the safety of the chickens by enriching and balancing the poultry diet, reducing the conversion feed, optimization of digestion, stimulation of the development of positive microflora in the gastrointestinal tract. The use of the complex probiotic preparation Immunoflor in the diet of young chickens at a dose of 15 g/t of water and 15 g/t of feed contributes to an increase in the number of erythrocytes, leukocytes and hemoglobin concentration, activation of cellular and humoral factors of nonspecific resistance of the body of chickens, providing a normal physiological state and homeostasis.

scholarly journals PROPHYLACTIC IMMUNODEFICIENCY OF DOGS COMPLEX BIOLOGICAL PREPARATION

2021 ◽  
pp. 66-74
Author(s):  
В.Г. СЕМЕНОВ ◽  
А.А. ИШТУДОВ ◽  
Д.А. НИКИТИН ◽  
В.А. АЛЕКСЕЕВ ◽  
А.С. ТИХОНОВ
Keyword(s):  
Research Work ◽  
Live Weight ◽  
Hemoglobin Concentration ◽  
The Body ◽  
Service Dogs ◽  
Humoral Factors ◽  
Veterinary Clinic ◽  
Biological Preparation ◽  
The Right ◽  
Experimental Group

Цель работы – изучение морфофизиологического профиля и неспецифических защитных сил организма служебных собак в условиях кинологического центра на фоне профилактики иммунодефицита биопрепаратами Dоg-Stim-N-B и Prevention-N-Е. Методология. Исследовательская работа проведена в условиях центра кинологической службы МВД и ветеринарной клиники «Айболит» г. Чебоксары на протяжении 2016-2020 гг. Для проведения научно-исследовательской работы подобрали три группы собак одной породы двухмесячного возраста по 5 особей в каждой (контрольная, 1-я и 2-я опытные). С целью профилактики иммунодефицита организма собакам опытных групп выполнили двукратное внутримышечное инъецирование биопрепаратов Prevention-N-Е (1-я опытная) и Dоg-Stim-N-B (2-я опытная) в дозе 0,1 мл на 1 кг живой массы. Результаты. Двукратная внутримышечная инъекция служебным собакам 1-й и 2-й опытных групп биопрепаратов Dоg-Stim-N-B и Prevention-N-Е на 61-63 и 68-69 сутки после рождения повышала концентрацию гемоглобина в крови по сравнению с контролем на 2,0-5,0 и 4,0-15,0 г/л, количество красных кровяных телец – на 1,09 и 1,10×1012/л, уровень общего белка – на 2,8-5,4 и 2,8-8,2 г/л, в том числе альбуминов – на 2,5-3,4 и 3,3-4,3 г/л, а γ-глобулинов – на 0,8-2,4 и 0,3-2,9 г/л. Кроме того, биопрепараты способствовали активизации клеточного и гуморального звеньев неспецифической устойчивости организма. Заключение. Разработанные биопрепараты Dоg-Stim-N-B и Prevention-N-Е стимулируют гемопоэз, развивают физиологическую эозинофилию, нейтрофилопению со сдвигом ядра вправо и лимфоцитоз, активизируют обмен белка, синтез альбуминов и γ-глобулинов, повышают активность клеточных и гуморальных факторов неспецифической резистентности организма. The purpose of the work – study of morphophysiological profle and non-specifc protective forces of the body of service dogs in the conditions of a canine center against the background of prevention of immunodefciency with biological preparation Dog-Stim-N-B and Prevention-N-E. Methodology. Research work was carried out in the conditions of the center of the canine service of the Ministry of Internal Afairs and the Aibolit veterinary clinic in Cheboksary during 2016-2020. For research work, 3 groups of dogs of one breed were formed at the age of 2 months, 5 heads in each group. In order to prevent immunodefciency of the body, dogs of the 1st experimental group were injected intramuscularly with the biopreparation Prevention-N-E at a dose of 0.1 ml/kg of live weight twice on the 61-63 and 68-69 day after birth, dogs of the 2nd experimental group at the same dose and at the same time injected with the biopreparation Dog-Stim-N-B. Results. Two-fold intramuscular injection to service dogs of the 1st and 2nd experimental groups of DogStim-N-B and Prevention-N-E biologics on the 61-63 and 68-69 day after birth increased blood hemoglobin concentration compared to 2 control.0-5.0 and 4.0-15.0 g/l, number of red blood cells - by 1.09 and 1,10 × 1012/l, the concentration of total protein - on 2.8-5.4 and 2.8-8.2 g/l, including the albumin fraction - on 2,5-3.4 and 3.3-4.3 g/l a γ-globulin - by 0.8-2.4 and 0.3-2.9 g/l. In addition, biologics contributed to an increase in plasma lysozyme activity and bactericidal activity of dog blood serum, which indicates an activation of the humoral link of the body's nonspecifc resistance. Conclusion. Biopreparation Dog-Stim-N-B and Prevention-N-E activate hematopoiesis, cause physiological eosinophilia, neutrophylopenia with neutrophilic nucleus shift to the right and lymphocytosis, stimulate protein exchange, synthesis of albumins and γ-globulins, increases cellular and humoral factors of non-specifc resistance

BIOGENIC AKWA-BIOT-NORM FEED ADDITIVE IN REALIZATION OF BIORESOURCE POTENTIAL OF STURGEON FISHES

2019 ◽  
Vol 1 (4) ◽  
pp. 441-448
Author(s):  
V.G. Tyurin ◽  
◽  
V.G. Semenov ◽  
N.I. Kosyaev ◽  
D.A. Nikitin ◽  
...  
Keyword(s):  
Growth And Development ◽  
Proteolytic Enzyme ◽  
Research Work ◽  
Feed Additive ◽  
General Increase ◽  
Nonspecific Resistance ◽  
General Protein ◽  
Absolute Quantity ◽  
Reliable Increase ◽  
Stimulation Of

Research work on an assessment of efficiency of biogenic Akwa-Biot-Norm feed additive developed by scientists is carried out. It is established that application to Lena sturgeon of biogenic feed additive on the basis of a polysaccharide complex of barmy cages Saccharomyces cerevisiae stimulated growth and development of fishes, promoted reliable increase in concentration of hemoglobin, both due to increase in quantity of erythrocytes, and due to increase of their functional activity that demonstrates activization of a gemopoez, increase in intensity of oxidationreduction processes and metabolism in general. Increase in absolute quantity of leukocytes, with the expressed increase in a share of lymphocytes and decrease in relative quantity of neutrophils, basophiles and eosinophils within physiological norms is revealed. These changes of leukocyte profile of Lena sturgeon testify to high extent of development of a cellular link of immunity. The amount of the general protein has increased in serum of blood of Lena sturgeon, which demonstrates activization of synthetic processes in organism of sturgeons and, as a result, increase the intensity of their growth. Significantly increased the value of such indicators of nonspecific resistance of organism of fishes as bactericidal activity of serum of blood for 4,0 %, phagocytic activity of neutrophils – for 5,5 % and concentration of proteolytic enzyme of lysozyme – for 142,9 % that demonstrates activization of cellular and humoral links of nonspecific resistance of an organism. The conducted researches are confirmed by efficiency of application of biogenic Akwa-Biot-Norm feed additive for stimulation of growth and prevention of incidence of fishes due to activization of nonspecific resistance of an organism in the conditions of ecological and technological pressure.

scholarly journals Physiological state of the broiler chickens organism on the background of combined stress and additive of humic acids and probiotic

2020 ◽  
Vol 22 (97) ◽  
pp. 157-161
Author(s):  
V. G. Stoyanovskyy ◽  
M. O. Shevchuk ◽  
I. A. Kolomiiets
Keyword(s):  
Functional Status ◽  
Humic Acids ◽  
Adaptive Systems ◽  
Broiler Chickens ◽  
Physiological State ◽  
Hemoglobin Concentration ◽  
Cost Effective ◽  
The Body ◽  
Combined Stress ◽  
Protective Function

The cultivation of broiler chickens is cost-effective given the high reproductive quality and growth rate of young growth at an early age. However, the management of the industry involves a number of technological operations that cause excessive stress on the adaptive systems, decrease the immunobiological reactivity of the bird organism, the development of stress and cause a decline in egg and meat productivity. Under these conditions, it is necessary to strengthen and stimulate the resistance of the body of the bird, to determine ways to eliminate the development of stressful states by providing full feeding. Therefore, the purpose of the study was to determine the morpho-functional status of the body of broiler chickens against the background of combined stress when included in the diet of humic acids “Reasil Humic Vet”, “Reasil Humic Health” and probiotics “Laktin”. For the 13th day of life, all livestock in a clinically healthy poultry were subjected to combined stress – revaccination (intranasal against Newcastle disease) + cold stress (for 60 min by conditioning the room and reducing the vivarium temperature by 5 °C). The study material was sampled 3 days after exposure to stress (corresponding to the anxiety stage), at 13, 20, and 26 days after exposure to stress (which accounted for the various stages of resistance stage development). It is established that the morpho-functional status of the body of broiler chickens on the background of combined stress is characterized at the stage of anxiety by reducing the concentration of hemoglobin and hematocrit by an average of 16.6 %, increasing the number of eosinophils and pseudo-eosinophils; at various stages of development of the stage of resistance – decrease in the number of red blood cells and hemoglobin concentration by 3.4–6.5 % against the background of increase of hematocritic value by 37.0 %, increase in the number of leukocytes by 17.2 % with a slight stabilization of respiratory and protective function of blood due to 26 days after stress. Influencing the formation of adaptive reactions of the body of broiler chickens of the experimental groups in the conditions of development of adaptation syndrome positive influence of the use of new biostimulants of natural origin “Reasil Humic Vet”, “Laktin” and “Reasil Humic Health” is shown, which is shown by the increase of hemoglobin concentration on average 13.0 % (P < 0.05), leukocyte count by 25.4 % (P < 0.05) due to lymphocytes 1.1 times (P < 0.05).

scholarly journals COMPARATIVE ASSESSMENT OF MORPHOLOGICAL STATE OF TROUT SEEDING AND COMMODITY SPECIES WHEN USING FORAGE WITH PROBIOTIC ADDITIVES

2020 ◽  
Vol 0 (1) ◽  
pp. 131-137
Author(s):  
Aigerim Aitkaliyeva ◽  
Shokhan Alpeisov ◽  
Asem Ibazhanova
Keyword(s):  
Rainbow Trout ◽  
Comparative Analysis ◽  
Physiological State ◽  
Biological Indicators ◽  
Control Fish ◽  
Physiological Status ◽  
Liver Structure ◽  
Probiotic Preparation ◽  
The Impact ◽  
Made In

The article highlights the experience of using the preparation Biocons and its effects on the physiological status of fish, its liver, gills and muscles. The results of the comparative analysis of muscle tissue showed that muscle reactions in both control fish and experimental fish have a whole spectrum of similar destructions. The use of domestic production feed with and without probiotic Biocons does not have a toxic effect on the liver structure. Therefore, the feed is safe for rearing fish. The purpose of the work is to justify experimentally the effectiveness of using the probiotic preparation Biocons as an additive in feed. The research tasks were set: experimental rearing of rainbow trout fry using various feeds, as well as feed with Biocons; conducting a comparative analysis of the results of rearing trout juveniles on various feeds, as well as feeds with Biocons as applied to farming and biological parameters; identifying the effect of various feeds on the physiological state of rainbow trout juveniles, their liver, muscles and gills. According to the research results based on the comparative analysis of the impact of three types of experimental starting and production artificial feed (feed without probiotic; feed with Biocons probiotic made in Kazakhstan and imported feed by AllerAqua, Dane) on the fish-breeding and biological indicators of trout juveniles and fingerlings it has been found that good results were obtained when using all of the above mentioned feeds.

STUDY OF CIRCADIAN BIOPHYSICAL PROPERTIES OF BIOACTIVE POINTS IN THE BODY

Vestnik ◽  
2021 ◽  
pp. 196-201
Author(s):  
М.С. Кулбаева ◽  
Э.Р. Намаз ◽  
Л.Б. Умбетьярова ◽  
С.Т. Тулеуханов ◽  
А. Ыдырыс ◽  
...  
Keyword(s):  
Electrical Conductivity ◽  
Physiological State ◽  
Research Work ◽  
High Energy ◽  
Time Of Day ◽  
The Body ◽  
Biologically Active ◽  
Adult Men ◽  
Biologically Active Points

Сегодня познание хронобиологических закономерностей существования является одной из актуальных задач биологии и медицины. Определение функционального состояния органов в теле человека в зависимости от времени суток - это одна из актуальных на сегодняшний день проблем. Основной целью исследовательской работы стала оценка физиологического состояния органов по показателям электропроводности биологически активных точек на коже, используемых в диагностических, лечебных, профилактических целях. В исследовании приняли участие 20 взрослых мужчин в возрасте от 20 до 25 лет, которые были относительно здоровыми, с устойчивым физиологическим состоянием. В качестве объекта исследования изучали показатели электропроводности 16 биологически активных точек, расположенных на стандартных меридианах. Оценивали статистически достоверные различия значений минимальной и максимальной электропроводности биоактивных точек из меридианов исследуемых органов в течение суток. Полученные результаты соответствуют времени, в период которого органы обеспечиваются жизненной энергией на высоком или низком уровне по концепции Чи, применяемой в народной медицине Китая. Значения высокой электропроводности приведены в соответствие с высокой энергетической ценностью, а значения низкой электропроводности - с пониженной энергетической ценностью. Today, the knowledge of the chronobiological laws of existence is one of the urgent tasks of biology and medicine. Determination of the functional state of organs in the human body depending on the time of day is one of the most pressing problems today. The main purpose of the research work was to assess the physiological state of organs by indicators of electrical conductivity of biologically active points on the skin, used for diagnostic, therapeutic, and prophylactic purposes. The study involved 20 adult men aged 20 to 25, who were relatively healthy, with a stable physiological state. As the object of the study, the indicators of electrical conductivity of 16 biologically active points located on standard meridians were studied. Statistically significant differences in the values of the minimum and maximum electrical conductivity of bioactive points from the meridians of the studied organs during the day were evaluated. The results obtained correspond to the time during which the organs are provided with vital energy at a high or low level according to the concept of Chi, used in traditional medicine in China. High conductivity values correspond to high energy values, and low conductivity values correspond to reduced energy values.

scholarly journals The use of ferment preparations to increase the defensive functions and to decrease the stress influence on calves

2020 ◽  
Vol 106 (2) ◽  
pp. 71-79
Author(s):  
Yu. Shchepetilnikov ◽  
Keyword(s):  
Live Weight ◽  
Protein Composition ◽  
The Body ◽  
Natural Resistance ◽  
Technological Regime ◽  
Humoral Factors ◽  
Enzyme Preparations ◽  
Stress Effects ◽  
Stress Influence ◽  
Stimulation Of

As a result of the studies, it was found that feeding calves with fodder enzyme preparations “Proxy” and “Respect” from 30 to 90 days of age in the composition of feed and contained under the conditions of the maximum permissible technological regime (GDTR) contributes to an increase in their live weight by 9, 9% and 10.2%, the intensity of their growth by 6% and 6.4%, gross growth – by 6.9% (p≤0.05). Enrichment of compound feed with enzymatic additives promoted an increase in the morphological and protein composition of the blood, as well as stimulation of cellular and humoral factors of nonspecific natural resistance of the body and a decrease in stress effects in calves.

scholarly journals THE INFLUENCE OF THE PHYSIOLOGICAL STATE OF RABBITS ON HEMATOLOGICAL INDICATORS WITH CHANGES IN THE AREA OF THE PLANTARY SURFACE OF THE FEET

2021 ◽  
Vol 246 (2) ◽  
pp. 262-267
Author(s):  
N.S. Khokhlova ◽  
◽  
V.V. Semenyutin ◽  
◽  
Keyword(s):  
Hematological Parameters ◽  
Physiological State ◽  
Hemoglobin Concentration ◽  
The Body ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Plantar Surface ◽  
Hind Limbs ◽  
Pregnancy And Lactation ◽  
Hematological Indicators

The influence of the physiological state of rabbits (pregnancy and lactation) on the hematological parameters of blood during changes in the area of the plantar surface of the feet of the hind limbs in conditions of cage keeping was studied. In the body of pregnant females, with the appearance of signs of hyperkeratosis and alopecia in the studied area of the feet, an increase in hemoglobin level occurs, an increase in MCH (mean corpuscular hemoglobin), MCV (Mean Corpuscular Volume), MCHC (corpuscular hemoglobin concentration) occurs, followed by a decrease in the development of hemorrhagic changes. The level of red blood cells has slight fluctuations. In lactating females, with the occurrence of alopecia and hyperkeratosis, an increase in the level of erythrocytes and hematocrit occurs with a simultaneous decrease in hemoglobin, and against the background of the development of hemorrhages, these indicators decrease, a decline in the values of MCH, MCHS and an increase in MCV are recorded. Regardless of the physiological state of the animal and changes in the area of the feet, the erythrocyte sedimentation rate (ESR) value and the level of leukocytes fluctuate within the limits of physiological values, which indicates the absence of an inflammatory process in the body. he revealed hematological changes indicate the development of adaptive processes in the event of hyperkeratosis and alopecia in the area of the plantar surface of the feet at various physiological conditions of rabbits with subsequent decompensating against the background of hemorrhagic changes.

USE OF DOMESTIC BIOPREPARATES FOR INCREASING THE MEAT QUALITY OF BULLS

2018 ◽  
Vol 1 (3) ◽  
pp. 88-94
Author(s):  
V. G. Tyurin ◽  
◽  
A. M. Smirnov ◽  
V. I. Dorozhkin ◽  
V. G. Semenov ◽  
...  
Keyword(s):  
Meat Quality ◽  
Russian Federation ◽  
The Body ◽  
Nonspecific Resistance ◽  
Humoral Factors ◽  
Resource Potential ◽  
State Register ◽  
Biological Potential ◽  
The Russian Federation

Scientifically substantiated and experimentally proved the feasibility of the zootechnical application of the developed biological products Prevention-N and Prevention N E in technology of beef production for the realization of bio-resource potential meat quality of calves of black-motley breed. Against the background of the use of biopreparations, activation of growth and development of bulls during cultivation, rearing and fattening was established, which led to higher slaughter and meat qualities of carcasses and, as a result, the yield of valuable cuts: spinogrudnogo – by 6.1 and 4.0 kg (P<0.01-0.001), lumbar – by 2.6 and 1.7 kg (P<0.05-0.01) and hip – by 8.6 and 7.1 kg (P<0.001). The quality of meat carcasses was proved by organoleptic, biochemical and spectrometric parameters and, consequently, the safety of the tested preparations. It was found that the implementation of the biological potential of the body of bulls due to the activation of hematopoiesis, cellular and humoral factors nonspecific resistance of biopreparations. The novelty of the obtained data is confirmed by the patents of the Russian Federation for invention № 2602687 and № 2622765 registered in the State register of inventions of the Russian Federation on 26.10.2016 and 19.06.2017, respectively.

scholarly journals Methods improving practical implementation of technology of combined recirculating fish farming and intensive crop production

2021 ◽  
Vol 0 (4) ◽  
pp. 105-114
Author(s):  
Elena Mikhailovna Evgrafova ◽  
Alexander Nickolaevich Nevalennyy ◽  
Lina Yurievna Lagutkina ◽  
Aliya Baimuratovna Akhmedzhanova ◽  
Elena Pershina
Keyword(s):  
Body Weight ◽  
Crop Production ◽  
Physiological State ◽  
Aquatic Organisms ◽  
Fish Farming ◽  
The Body ◽  
Organic Load ◽  
Physiological Status ◽  
Practical Implementation ◽  
Feeding Rates

The article focuses on the problem of adopting the effective methods for combined cultivation of food products in cities, which requires the rapidly deployable and scalable aquaponic urban farms for year-round cultivating the aquaculture and crop products. Experimental work on cultivating the agricultural products in a small-sized system of combined recirculating fish farming and intensive crop production (aquaponics) has been carried out. A well-grounded idea of the qualitative and quantitative requirements for feed formulations, the possibilities of their optimization due to including the ingredients of natural origin was obtained. With combined recirculating fish farming and intensive crop production the control over the physiological state of the aquatic organisms grown on feed on their own formulation is carried out on the analysis of special biochemical parameters, which complement the general characteristics of the limits of reference values of homeostasis constants and determine the physiological status of fish. Feeding rates (% of body weight) of fish determine the amount of organic load for nutrition of plant growing objects, in particular leafy greens. In the course of research it was found out that when feeding sterlet (100 g) with the developed feed with protein content 45% the feeding rate is 4% of the body weight. The equivalent area 1 m2 with leafy greenery accounts for 40–50 g of feed with a mass of water bodies up to 5.0 kg/m3.

Evaluation of clinical efficacy of Derinat® in form of spray in practice of district therapist

2019 ◽  
Vol 1 (9) ◽  
pp. 38-46
Author(s):  
A. P. Babkin ◽  
A. A. Zuikova ◽  
O. N. Krasnorutskaya ◽  
Yu. A. Kotova ◽  
D. Yu. Bugrimov ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Respiratory Diseases ◽  
Viral Infections ◽  
Pharmacological Action ◽  
The Body ◽  
Natural Resistance ◽  
Acute Respiratory Diseases ◽  
T Helpers ◽  
T Killers ◽  
Stimulation Of

The widespread worldwide spread of acute respiratory diseases is an urgent problem in health care. Expressed polyetiology of respiratory diseases does not allow to limit the use of specific vaccine preparations and dictates the need to use to combat them a variety of non-specific means that stimulate the natural resistance of the human body. The main pharmacological action of sodium deoxyribonucleate is the stimulation of phagocytic activity of T-helpers and T-killers, increasing the functional activity of neutrophils and monocytes/ macrophages, providing regeneration and repair processes in the epithelial component of antiviral protection of the body. Based on the above, the study of the clinical efficacy of Derinat® in the form of spray in the treatment of acute respiratory viral infections is relevant.

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