scholarly journals Clinical characteristics of patients with chronic cough in Guangdong, China: a multicenter descriptive study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kefang Lai ◽  
Lianrong Huang ◽  
Haijin Zhao ◽  
Feng Wu ◽  
Guocui Zhen ◽  
...  
Keyword(s):  
Educational Level ◽  
Chronic Cough ◽  
Respiratory Symptoms ◽  
Clinical Characteristics ◽  
Descriptive Study ◽  
Single Center ◽  
Cross Sectional ◽  
Tertiary Hospitals ◽  
Male Patients ◽  
Nocturnal Cough

Abstract Background The clinical characteristics of patients with chronic cough are reported only in single-center survey in China, being significantly different from that in western countries. Here, we performed a multicenter study to describe the clinical characteristics of chronic cough patients. Methods A cross-sectional observational survey was conducted in thirteen tertiary hospitals of Guangdong, South China. Relevant data were recorded using a standardized questionnaire and analyzed, including demographics, educational attainment, cough features, and concomitant symptoms. Results Of 933 patients in this study, the median age was 40.0 (IQR 31.0–52.0) years with a peaked age of 30–39 years. The proportion of females (487, 52.2 %) was comparable to that of males (446, 47.8 %). Up to 81.9 % of the patients were non-smokers. More than two-thirds of the subjects with chronic cough had a low educational level. The median cough duration was 6.0 (IQR 3.0–24.0) months, and 73.0 % of chronic cough patients presented with dry cough. Laryngeal paresthesia was the most common concomitant symptom (704, 75.5 %), followed by rhinitis/sinusitis-related (350, 37.5 %) and respiratory symptoms (322, 34.5 %). Rhinitis/sinusitis-related symptoms more frequently occurred in patients with productive cough than in those with dry cough (49.0 % vs. 33.0 %, P < 0.001). Moreover, female patients displayed an older age and a higher prevalence of nocturnal cough compared to male patients (both P < 0.05). Conclusions Our results show an equal gender, young profile and laryngeal paresthesia in patients with chronic cough, and different clinical features between females and males.

scholarly journals Clinical characteristics and in-hospital outcome of heart failure in women: a single center registry from Egyptian cardiac care unit

2019 ◽  
Vol 71 (1) ◽  
Author(s):  
Hala Mahfouz Badran ◽  
Marwa Ahmed Elgharably ◽  
Naglaa Faheem
Keyword(s):  
Clinical Characteristics ◽  
Heart Diseases ◽  
University Hospital ◽  
Cardiac Care ◽  
Single Center ◽  
Term Outcome ◽  
Cross Sectional ◽  
Valvular Heart Diseases ◽  
Significant Difference ◽  
Cardiac Care Unit

Abstract Background This study represents figures from a cardiac care unit (CCU) of a university hospital; it describes an example of a tertiary academic center in Egypt and provides an epidemiological view of the female HF patients, their risk profile, and short-term outcome during hospitalization. Results It is a local single-center cross-sectional observational registry of CCU patients 1 year from July 2015 to July 2016. Patient’s data were collected through a special software program. Women with evidence of HF were thoroughly studied. Among the 1006 patients admitted to CCU in 1 year, 345 (34.2%) patients were females and 118 (34.2%) had evidence of HF, whereas 661 (65.7%) were males and 178 (26.9%) of them had HF. Women with HF showed 11.7% prevalence of the total population admitted to CCU. 72.7% were HFrEF and 27.3% were HFpEF. Compared to men, women with HF were older in age, more obese, less symptomatic than men, had higher incidence of associated co-morbidities, less likely to be re-admitted for HF, and less likely to have ACS and PCI. Valvular heart diseases and cardiomyopathies were the commonest etiologies of their HF. Women had more frequent normal ECG, higher EF%, and smaller LA size. There is no difference in medications and CCU procedures. While females had shorter stay, there is no significant difference in hospital mortality compared to male patients. Conclusions Despite higher prevalence of HF in females admitted to CCU and different clinical characteristics and etiology of HF, female gender was associated with similar prognosis during hospital course compared to male gender.

Prevalence of and risk factors for respiratory symptoms in an adult urban population

2021 ◽  
Vol 25 (1) ◽  
pp. 16-22
Author(s):  
Z. Akhter ◽  
S. Razzaq ◽  
U. Rabbani ◽  
M. Irfan ◽  
P. Burney ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Cough ◽  
Respiratory Symptom ◽  
Respiratory Symptoms ◽  
Common Symptom ◽  
Cross Sectional Survey ◽  
Community Based ◽  
Cross Sectional ◽  
Pakistani Population ◽  
Multi Stage

OBJECTIVE: To determine prevalence of and risk factors for respiratory symptoms in an adult urban Pakistani population.METHODS: We conducted a multi-stage, community-based, cross-sectional survey from May 2014 to August 2015, comprising 1629 adults from 75 random clusters in Karachi using questionnaire-based interviews.RESULTS: Around 60% of participants were females and 43% belonged to the >37 years age group. At least one respiratory symptom was reported by 37.5% of participants. Breathlessness was the most common symptom (25.2%, 95%CI 23.1–27.3), followed by acute wheeze (10.1%, 95%CI 8.7–11.7). Multivariable models revealed that males and those aged >37 years were more likely to report acute and chronic phlegm and bronchitis, and breathlessness. Participants with a higher level of education were less likely to report acute and chronic cough. Participants with >5 years pack-years of smoking were more likely to report acute and chronic cough and breathlessness. Other risk factors included passive smoking, regular use of air conditioning and mosquito coils, wet spots and mould in the house, and exposure to dusty jobs.CONCLUSION: We found breathlessness to be the most prevalent respiratory symptom and identified various risk factors for respiratory symptoms.

Patterns of KRAS, NRAS and BRAF testing among patients with metastatic colorectal cancer in the EU5.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 637-637
Author(s):  
Kimberly Lowe ◽  
Xin Niu ◽  
George Kafatos ◽  
Michael Anthony Kelsh
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Real World ◽  
Clinical Characteristics ◽  
Descriptive Study ◽  
Data Availability ◽  
Wild Type ◽  
Cross Sectional ◽  
Patient Demographic ◽  
Biomarker Testing

637 Background: In mid-2013, the requirement for mCRC patients treated with panitumumab changed from wild-type KRAS to wild-type RAS ( KRAS and NRAS). The objective of this study was to describe patterns of KRAS, NRAS, and BRAF testing among mCRC patients in the EU5 (United Kingdom (U.K.), Germany, France, Italy and Spain). Methods: This descriptive study utilized Oncology Analyzer data (IMS Health Oncology, Fairfield, CT, USA), which provides real-world quarterly cross-sectional, epidemiologic and clinical data for mCRC patients. Trends in biomarker testing during the study period were evaluated by calculating the frequencies and proportions of patients who were /were not tested for combinations of KRAS, NRAS, and BRAF within each of the five countries. KRAS and BRAF data were available in all countries from quarter three (Q3) 2012 to quarter two (Q2) 2015. NRAS was available in all countries from quarter 1 (Q1) 2014 to Q2 2015. Frequencies and proportions were also calculated to summarize patient demographic and clinical characteristics between groups with different testing choices. Results: A total of 32,961 patients with mCRC were included in the analyses. Prior to 2013, the majority of patients in each country were tested for only KRAS. The proportion of patients tested for both KRAS and NRAS increased substantially during the period of data availability for NRAS (Q1 2014 to Q2 2015), including <1% to 19.1% in the U.K., 8.8% to 31.9% in France, 13.1% to 43.2% in Germany, 5.9% to 24.6% in Italy, and 8.7% to 31.4% in Spain. The proportion of patients who were tested for all three biomarkers also increased during the period of data availability for all three biomarkers (Q1 2014 to Q2 2015), including 2.3% to 16.4% in the U.K., 4.8% to 26.6% in France, <1% to 2.4% in Germany, 4.2% to 22.3% in Italy, and 1.5% to 9.3% in Spain. There were few differences in patient demographic or clinical characteristics between those with different testing groups. Conclusions: This analysis provides a description of biomarker testing using read-world data and suggests an overall increase in testing among mCRC patients in the EU5. Although there was a trend towards increased testing, many mCRC patients are still not tested for these important biomarkers.

scholarly journals Prevalence of Preoperative Anxiety in Preoperative Patients in Nepal Police Hospital: A Cross-sectional Descriptive Study

2021 ◽  
Vol 4 (1) ◽  
pp. 85-88
Author(s):  
Sundar Prasad Hyoju
Keyword(s):  
Descriptive Analysis ◽  
Sampling Technique ◽  
Descriptive Study ◽  
Negative Consequences ◽  
Cardiac Events ◽  
Cross Sectional ◽  
Female Patients ◽  
Pain Ratings ◽  
Male Patients ◽  
Preoperative Patient

Introduction: The possibility of undergoing anesthesia-assisted surgery can cause a great deal of anxiety in individuals. Excessive anxiety can have a number of negative consequences, including perioperative cardiac events, greater anesthetic needs, higher postoperative pain ratings, and a longer stay in the hospital. Anxiety levels during surgery might be influenced by a variety of reasons. The objective of the study was to estimate the prevalence of anxiety in adult patients scheduled for Surgery. Methods: This is Cross-sectional Descriptive Study conducted in Nepal police hospital with calculated sample size of 92 with round figure of 100, convenient sampling technique was used. Descriptive analysis was used for Analysis. Results: Prevalence of anxiety in preoperative patient was 31%. The prevalence in male patients and female patients were 21.2% and 39.5% respectively. Conclusions: When compared to many other research, the general prevalence of anxiety at Nepal Police Hospital was lower; nevertheless, the incidence was higher among female patients.

scholarly journals Knowledge and Practices of Wound Care Among Animal Bite Cases Attended at Institute of Public Health

2013 ◽  
Vol 24 (1) ◽  
pp. 27-30
Author(s):  
Rowshan Ara ◽  
Md Nasir Uddin ◽  
Md Abdul Wahab ◽  
Shahneela Ferdousi ◽  
Lubna Khondker ◽  
...  
Keyword(s):  
Public Health ◽  
Educational Level ◽  
Wound Care ◽  
Descriptive Study ◽  
Educational Programme ◽  
Cross Sectional ◽  
Female Ratio ◽  
Male And Female ◽  
Medicine Today ◽  
Attending Physicians

Animal bite is common in Bangladesh. A cross sectional  type of descriptive study was carried out at the Institute of  Public Health (IPH), Dhaka to find out the knowledge and  practices related to wound care among animal bite cases  during the month of February, 1998. A total of 200 patients  were interviewed, 55% of them came from urban area.  Maximum (65.5%) patients were teenagers and adult (above  13 yrs.) with mean age 22.15 yrs. Male and female ratio  was 80.5:19.5. Majority of cases were poor (76.5%) and  only 12% attained educational level of SSC pass or above.  In 92.5% cases dog was the biting animal, 60% of which  were stray. Only 91(45.5%) patients took immediate  measures for wound care. Of them only 11 patients knew  and washed the wound by soap and water and 3 patients did  it after getting advice from physicians. 134 (67%) patients  consulted with physicians one hour to several days after,  whereas 33% within one hour. Among the attending  physicians 31.5% were MBBS doctors but 57.5% were  Kabiraz, Fakir, Moullana and others. In 50 present animal  bite cases, Fold remedies or herbal medicine were advised  in comparison to 42% for vaccination. But only 3 (1.5%)  patients got the message of wound care by washing with  soap and water. Emphasis on planning on educational  programme on "What people should do after an animal  bite" has been recommended. DOI: http://dx.doi.org/10.3329/medtoday.v24i1.14111 Medicine TODAY Vol.24(1) 2012 pp.27-30

scholarly journals Eosinopenia Phenotype in Patients with Coronavirus Disease 2019: A Multi-center Retrospective Study from Anhui, China

2020 ◽  
Author(s):  
Yusheng Cheng ◽  
Yun Zhou ◽  
Mengde Zhu ◽  
Lei Zha ◽  
Zhiwei Lu ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Clinical Characteristics ◽  
Research Question ◽  
Gastrointestinal Symptoms ◽  
Public Health Emergency ◽  
Laboratory Findings ◽  
Tertiary Hospitals ◽  
Male Patients ◽  
Design And Methods ◽  
Severe Type

AbstractBackgroundCoronavirus disease 19 (COVID-19) has become a global unprecedented pandemic infecting more than one millon people, which is declared by WHO as a international public health emergency. Eosinopenia may predict a poor prognosis of COVID-19. However, to date, there is no detailed analysis of the clinical characteristics of COVID-19 patients with eosinopenia.Research questionThe aim of this study was to describe clinical characteristics of COVID-19 patients with eosinopenia.Study Design and MethodsThis was a multi-center retrospective study conducted in three tertiary hospitals. A total of 59 patients with COVID-19 were reviewed from January 23, 2020 to March 10, 2020. We described clincial characteristics of patients with COIVD-19 and eosinopenia phenotype.ResultsThe median age of patients with COVID-19 was 39 years old, and 32 (54,2%) were male. Patients with severe type had higher proportions of dyspnea (50%) and gastrointestinal symptoms (50%) compared with mild or moderate patients. Laboratory findings indicated that lower counts of lymphocyte and eosnophils were observed in patients with severe type. Cough, sputum, and fatigue were more common symptoms in eosinopenia patients compared with non-eosinopenia patients. High proportion of comorbidities was observed in eosinopenia patients. Laboratory findings indicated that lymphocyte counts (median: 101 cells/μl) in eosinopenia patients were significantly less than those of non-eosinopenia patients (median: 167 cells/μl, p<0.001). The use of corticosteroids therapy in COVID-19 patients with eosinopenia were notably higher than those in patients with non-eosinopenia (50% vs 13.8%, respectively, p=0.005). Compared with parameters in non-eosinopenia patients, eosinopenia patients were more inclined to have less lymphocyte counts (OR value 6.566, 95%CI[1.101-39.173], p=0.039).InterpretationEosinopenia are very common in COVID-19 patient, particularly in severe patients. Common symptoms included fever, cough, sputum, and fatigue are frequent in eosinopenia patients. Eosinopenia may represent a novel phenotype in COVID-19, which needs further investigation.

Prevalence of smoking in an urban population in the province of Alicante / Prevalencia del tabaquismo en una población periurbana de la provincia de Alicante

2003 ◽  
Vol 2 (2) ◽  
Author(s):  
José Mª Ortín Arroniz ◽  
Juan Custardoy Olavarrieta ◽  
Manuel Pineda Cuenca ◽  
José G. Cano Montoro ◽  
Maite Andreu ◽  
...  
Keyword(s):  
Educational Level ◽  
Random Sampling ◽  
Urban Population ◽  
Descriptive Study ◽  
High Association ◽  
Cross Sectional ◽  
High Tendency ◽  
Low Level ◽  
Las Mujeres ◽  
The Unemployed

Objetivo: Conocer la prevalencia del hábito tabáquico en la población de Albatera (Alicante) e identificar su asociación con otras variables epidemiológicas. Material y Método: Estudio descriptivo transversal. Muestreo aleatorio polietápico proporcional con definición de cuotas muéstrales, según grupos de edad y sexo. Se administró una encuesta sobre hábito tabáquico, nivel educativo, profesión, ocupación, situación laboral y uso de anticonceptivos en las mujeres . Resultados: El 86 % de las personas seleccionadas participaron en el estudio (N=644). La prevalencia de tabaquismo hallada ha sido del 32,8 ± 3,6% (40,2% en hombres y 25,4% en mujeres), la mayor tasa la encontramos entre los 20-39 años. El consumo medio de cigarrillos fue de 15,8 cig./día. El 47,2 % de los hombres y el 44,5 % de las mujeres fumadoras trabajaban, frente al 40,9 % de hombres y 33,3 % de mujeres paradas. La mitad de las mujeres que tomaban anticonceptivos fumaban.Conclusiones: La prevalencia del tabaquismo en nuestra población es inferior a la de la población española en general. Se da un elevado porcentaje de fumadores entre población más joven, con incremento significativo en mujeres de edades comprendidas entre 20-29 años. Existe una mayor tendencia en la adquisición del habito tabáquico en la población con menor nivel de estudios y situación de paro laboral. También una elevada asociación entre el de consumo de anticonceptivos y tabaquismo activo. AbstractAim: To know the prevalence of the tobacco habit in Albatera population (Alicante) and to identify its association with other epidemiological variables. Material and Method: Cross sectional descriptive study. Random sampling proportional with quotas definition, according to sex and aged groups. A survey about tobacco habit, educational level, profession, occupation situation and the use of contraceptive in women was administered. Results: 86% of selected subjects ( N= 644) participated in the study. The prevalence of tobacco habit was between 32,8 +/-3,6% (40,2% in men and 25,4% in women). The highest rate was found for for subjects aged from 20 to 39 years. The average of cigarettes consumption was 15,8 cig/day. 47,2% of smoker men (no entiendo en el resumen en español si se refiere a hombres y mujeres fumadoras o solo mujeres) and 44,5% of smoker women were working (creo que te refieres a que eran trabajadores porque si es asi puedes poner were workers), while 40,9% of men and 33% of women were unemployed. Half of women that were taking contraceptive also smoked. Conclusions: The prevalence of tobacco habit in our population is lower than in the spanish general population. An elevated percentage of smokers was found in the youngest population , with a significant increase in women between 20 to 29 years. The population with low level of studies and who were unemployed (puedes poner the unemployed population and with a low level of studies) has a high tendency to smoke as a habit than other groups. There is also a high association between contraceptives consumption and active tobacco habit.

Sex Differences in the Clinical Profile Among Patients With Gout: Cross-sectional Analyses of an Observational Study

2020 ◽  
pp. jrheum.200113 ◽  
Author(s):  
Ritch te Kampe ◽  
Matthijs Janssen ◽  
Caroline van Durme ◽  
Tim L. Jansen ◽  
Annelies Boonen
Keyword(s):  
Sex Differences ◽  
Clinical Characteristics ◽  
Newly Diagnosed ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Research Findings ◽  
Male Patients ◽  
Menopausal State ◽  
Insight Into

Objective Research findings in gout result predominantly from studies about men and might not be generalizable to women. To improve insight into sex differences in gout, our study compared clinical characteristics and comorbidities of female and male patients with gout, and explored the influence of menopause on these differences. Methods Data from patients referred to 2 rheumatology clinics and diagnosed with gout were used. Clinical characteristics and comorbidities of each sex were compared univariately. Sex difference in comorbidities were further explored in multivariate logistic regression analyses adjusting for age, BMI, smoking, and alcohol consumption in both the total group and in those with gout onset ≥ 55 years (as a surrogate for menopausal state). Results There were 954 patients, including 793 (83%) men, included. Women were on average older (65 vs 62 yrs), were more often obese (54% vs 36%), had a higher serum uric acid (sUA) level (0.53 vs 0.49 mmol/L), used diuretics more often (60% vs 30%), and consumed alcohol less frequently (47% vs 72%). Additionally, women more frequently had reduced renal function (64% vs 31%), hypertension (78% vs 56%), heart failure (23% vs 12%), and type 2 diabetes (39% vs 17%; all P < 0.05). In those with gout onset ≥ 55 years, differences in comorbidities were less pronounced and disappeared after adjusting for lifestyle. Conclusion Our study confirmed sex differences in clinical characteristics and comorbidities among newly diagnosed patients with gout, and revealed that sex differences in comorbidities among those with gout onset beyond the age of female menopause were strongly attenuated and fully explained by lifestyle.

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