scholarly journals Dynamics of morphological and biochemical indicators of blood of sucking piglets at different levels of iodine citrate in sows rations

2018 ◽  
Vol 20 (84) ◽  
Author(s):  
R. V. Hunchak ◽  
H. M. Sedilo
Keyword(s):  
Biochemical Parameters ◽  
Experimental Studies ◽  
The Body ◽  
Control Group ◽  
Metabolic Reactions ◽  
Hematological And Biochemical Parameters ◽  
Physiological Values ◽  
High Bioavailability ◽  
Positive Effect

The article presents the results of experimental studies on the determination of the influence of iodine citrate on hematological and biochemical parameters of blood of sucking piglets. It was established that hemopoiesis and metabolic reactions in pigs depend on the level of Iodine in the sows, and in the later period (the 10th day) and from the receipt of the biometal as part of the prestarter. Iodine, in nanocitate form, at the expense of high bioavailability and chemical activity, provided the need for thyroid gland in it in much less quantities than the amounts recommended for pregnant and lactating sows in the form of potassium iodide. It has been established that at the admission to the body of a sow 0.095–0.19 mg/kg of feeding of iodine in a nanocyte form (1/4–1/2 of the recommended amount of iodine in the form of CI), its positive effect on hemopoiesis and metabolic processes in newborn piglets is peculiar (increased number of red blood cells, hemoglobin content, high percentage of lymphocytes, increases in the concentration of total protein and in particular albumin, against the backdrop of growth in blood plasma levels of CSF, the concentration of hormones T3 and T4 is quite stable. A higher dose in the premix of iodine citrate (1 : 1) is irrational and most likely undesirable, since against the background of inhibition of this group of erythropoiesis, eosinophilia and lymphopenia, the protein synthesis function decreases and the activity of AlAT, AsAT increases. Hematological and biochemical parameters of blood of piglets obtained from sows, which received a minimum amount of iodine in the form of citrate (0.1 : 1) with premix, did not undergo significant changes, were within the limits of physiological values, although in comparison with the animals of the control group, and particularly, the piglets of the group D2 and D3 tended to decrease (growth). Consequently, iodine citrate as a source of iodine for pregnant and subsistence sows can be recommended in the amounts: 0.095–0.19 mg/kg and 0.125–0.25 mg/kg feed.

scholarly journals The effect of the insect-acaricidal drug Delcid 7.5® on the body of rabbits

2021 ◽  
Author(s):  
M.I. Burmistrova ◽  
F.I. Vasilevich ◽  
A.A. Deltsov
Keyword(s):  
Peripheral Blood ◽  
Biochemical Parameters ◽  
Hematological Parameters ◽  
Spinal Column ◽  
The Body ◽  
Control Group ◽  
Toxicological Effect ◽  
Hematological And Biochemical Parameters ◽  
External Stimuli ◽  
Average Hemoglobin

The effect of the drug Delcid 7.5 ® on the clinical, hematological and biochemical parameters of rabbits of the New Zealand breed, 6 months of age, when used in doses of 2 ml or 4 ml. Three times with a cutaneous application along the vertebral column from the head to the tail. The conducted studies allow us to conclude that after applying the drug in these doses for 3 days, there were no external signs of intoxication in rabbits. All the animals of the experimental groups were active. The reaction to external stimuli is preserved. Hematological parameters of peripheral blood (number of erythrocytes, leukocytes, hemoglobin, color index, the average hemoglobin content of PG in erythrocytes, mean corpuscular volume, the exponent of anisocytosis of red blood cells, etc.) of the experimental group after treatment in 5, 15, 25 days had no significant differences from those in the control group, this suggests that the applied drug to the skin along the spine from the withers to the rump at a dose of 2 and 4 ml has no Toxicological effect on peripheral blood. The leukogram of the peripheral blood of rabbits when using the drug did not differ from the control parameters. The analysis of biochemical parameters (activity of aminotransferase, alkaline phosphatase, lactate dehydrogenase, creatinine, urea, glucose, total protein, bilirubin, etc.) of the blood of the experimental groups when applying the drug Delcid 7.5 ® along the spinal column at the maximum therapeutic dose did not reveal statistically significant differences from the control, which indicates that the drug does not have a genotoxic effect, does not interfere with the kidneys and metabolism in the body of rabbits. The results of the conducted studies show that the insecticide-acaricide drug Delcid 7.5® for veterinary use, developed by NVC Agrovetzashchita LLC, is safe for rabbits, and therefore it can be recommended for studying the effectiveness of acarosis in rabbits and other animal species.

scholarly journals Influence of new recipes of feed additives on the biochemical status of the blood of Simmental cattle in Yakutia

2021 ◽  
pp. 62-66
Author(s):  
Nurgustana Mikhailovna Alekseeva ◽  
Paraskovya Prokopyevna Borisova ◽  
Natalia Afanasyevna Nikolaeva
Keyword(s):  
Biochemical Parameters ◽  
Blood Parameters ◽  
Feed Additives ◽  
The Body ◽  
Local Resources ◽  
Biochemical Status ◽  
New Formulation ◽  
Positive Effect ◽  
Experimental Group

The article presents the results of the influence of new recipes for feed additives made on the basis of local resources on the biochemical parameters of the blood of dairy cows of the Simmental breed in the conditions of Yakutia. Research objectives: 1) study the chemical composition of new recipes for feed additives produced from local resources; 2) determination of the influence of the new formulation of feed additives from local resources on the biochemical parameters of blood in cattle of the Simmental breed. In our experiments, there were no statistically significant changes in the biochemical parameters of blood during the period of the experiments, all the studied blood parameters, both at the beginning and at the end of the experiments, in all groups of animals were within the physiological norms and did not have significant differences between the groups. Consequently, feeding the formulation of feed additives in the composition of Tammi barley, Tuymaada wheat, Pokrovsky and Vilensky oats, dry brewer's grain, Hongurin zeolite, Hongurinobakt probiotic in the diet of cows and heifers of the Simmental breed contributed to the activation of vital processes in the body, assimilation of feed and improved appetite. It should be noted that the cows of the II-experimental group showed a tendency to increase the composition of amino acids. At the beginning of the experiment, the blood lysine content increased by 5.22 mg /% compared with the control and by 5.79 mg /% with the I-experimental group, methionine by 19.67 mg /% and by 10.02 mg /% respectively. The same pattern is observed for the rest of the amino acid composition at the end of the experiment. The data obtained indicate that the optimization of the feed rations of Simmental cows in terms of the content of vitamins of groups A and C through the use of the formulation of protein-vitamin-mineral feed additives had a positive effect on the hematopoietic function. So, if the content of vitamins A and C at the beginning of the experiment was less, then at the end of the experiment the same indicators returned to normal.

scholarly journals Effects ofSalvadora persicaExtract on the Hematological and Biochemical Alterations against Immobilization-Induced Rats

Scientifica ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Kholoud S. Ramadan ◽  
Salha A. Alshamrani
Keyword(s):  
Biochemical Parameters ◽  
Hematological Parameters ◽  
Hdl Cholesterol ◽  
Treated Group ◽  
Control Group ◽  
Serum Samples ◽  
Salvadora Persica ◽  
Biochemical Alterations ◽  
Hematological And Biochemical Parameters

A total of 24 rats were divided into 4 groups: control, stress, extract alone, and stress + extract (n=6each), for total 21 days of treatment. The immobilization stress was induced in rats by putting them in 20 cm × 7 cm plastic tubes for 2 h/day for 21 days. Rats were postorally treated withSalvadora persicaat a dose of 900 mg/kg body weight via intragastric intubations. At the end of the test period, hematological and biochemical parameters were determined in blood and serum samples with determination of vital organs weights. The vital organ weights were not significantly affected in stressed rats as compared to control rats. Compared to the control group, the stress treated group showed significances in several hematological parameters, including decreases in WBC, RBC, and PLT counts. Furthermore, in comparison to the control group, the stress group showed significantly increased blood glucose, serum total cholesterol, LDL-cholesterol, and triacylglycerols levels and decreased HDL-cholesterol level. The hematological and biochemical parameters in the stress + extract treated group were approximately similar to control group. The SP extract restored the changes observed following stress treatment.

scholarly journals Comparative analysis of biological activity of probiotic preparations based on Enzymesporine

2021 ◽  
Vol 37 ◽  
pp. 00017
Author(s):  
Alexander Gorobets ◽  
Denis Trubnikov
Keyword(s):  
Weight Gain ◽  
Biochemical Parameters ◽  
Daily Weight Gain ◽  
Control Group ◽  
Control Groups ◽  
Physiological Limit ◽  
Probiotic Preparation ◽  
Hematological And Biochemical Parameters ◽  
High Level

In the article the influence of using the microencapsulated probiotic preparation Enzymesporine with an enzyme in comparison with analogues that do not have an enzyme (microencapsulated and non-encapsulated) in pigs of Genesus selection is considered. The activity on intestinal digestion, growth and weight gain, and on hematological and biochemical parameters is studied. The period of life of pigs during the experiment was 48-98-148 days. In the course of the performed experiment on pigs of Genesus selection, after the usage of reliable results. The increase in the life weight and daily weight gain in the period from the 48th to the 148th day of life has been confirmed. That indicates the advantages of the microencapsulated probiotic preparation Enzymesporine with an enzyme over microencapsulated and non-encapsulated analogues without an enzyme. The general analysis of blood showed that the animals that received microencapsulated Enzymesporine with an enzyme. Along with that the content of erythrocytes and hemoglobin reached the upper physiological limit, which is significantly higher than that in the control groups. During the determination of biochemical parameters of blood a significant increase of the amount of total protein and albumins in experimental animals was detected up to 148 days of animals’ life. A significantly high level of immunoglobulins was observed throughout the experiment in the tested animals. When comparing with the control group, that indicates a high resistance to diseases and a high immune status of pigs.

scholarly journals Toxicological Study of Malic acid-Phthalic acid-Propane- 1,2-diol Copolyester

1970 ◽  
pp. 150-156
Author(s):  
M Amirul Islam ◽  
Sefaly Khatun ◽  
MA Bakr
Keyword(s):  
Malic Acid ◽  
Biochemical Parameters ◽  
Phthalic Acid ◽  
Harmful Effect ◽  
Biochemical Parameter ◽  
The Body ◽  
Control Group ◽  
Haematological Parameter ◽  
Body Weights ◽  
Hematological And Biochemical Parameters

Malic acid-phthalic acid-propane 1,2-diol copolyester (MPPC) was administered intraperitoneally to the rats at a dose of 300 μg rat-1day-1 for 21 consecutive days to find out its harmful effect on rats. The gross general observations such as changes of body weight, hematological profiles, biochemical parameters of blood and the histopathology of liver, kidney, heart, lungs and spleen were investigated in control and experimental rats. The body weights of the rats were slightly increased. The changes of hematological and biochemical parameters were statistically insignificant. No abnormalities were found in the histopathology of the liver, kidney, heart, lung and spleen in the experimental group of rats when compared with control group of rats. From this study, it was inferred that malic acid- phthalic acid-propane 1,2-diol copolyester would be used as a matrix for controlled and sustained release of drugs. Key words: Malic acid-phthalic acid-propane 1,2-diol copolyester, sub-acute toxicity, haematological parameter, biochemical parameter, histopathology. DOI = 10.3329/jard.v5i1.1472 J Agric Rural Dev 5(1&2), 150-156, June 2007

scholarly journals Influence of vitamin-mineral supplement on protein metabolism in rabbits’ organisms

2021 ◽  
Vol 4 (1) ◽  
pp. 3-6
Author(s):  
M. Fedorchenko
Keyword(s):  
Blood Plasma ◽  
Protein Content ◽  
Biochemical Parameters ◽  
The Body ◽  
Control Group ◽  
Total Protein Content ◽  
Mineral Supplement ◽  
Significant Difference ◽  
Positive Effect ◽  
Alt Activity

The purpose of the study is to study the influence of different vitamin-mineral supplement “Tekro” doses on biochemical parameters in blood plasma and liver of rabbits of New Zealand breed. The research methodology is based on research according to generally accepted research methods. Biochemical parameters were studied in rabbits’ organisms at 45, 60, 75 and 90 days of rearing with feeding of different doses of vitamin-mineral supplement “Tekro”, namely 3 %, 3.5 %, 4 %. The academic novelty is that nowadays the problem of the effect of different vitamin-mineral supplement “Tekro” doses on biochemical parameters in the blood and liver of rabbits has not been studied. Analyzing the indicators of the total protein content in the blood plasma of rabbits of the experimental groups and the control one for 90 days, it was noted that there was no significant difference in the indicators. In the liver of rabbits of the age from 45 to 90 days there was a tendency to increase the protein content due to the effects on the body of various doses of vitamin and mineral supplement “Tekro”. It has been established the positive effect of vitamin-mineral supplement “Tekro” on ALT activity of rabbits in experimental groups. At the age of 75 days, significantly higher ALT activity was recorded in rabbits of the 3rd experimental group by 35.8 % compared to animals in the control group.

scholarly journals Endurance product for sprinters

2021 ◽  
Vol 83 (1) ◽  
pp. 253-257
Author(s):  
A. N. Shcheglevatyh ◽  
S. A. Ovechkin
Keyword(s):  
High Speed ◽  
The Body ◽  
Control Group ◽  
Main Task ◽  
Nutritional Improvement ◽  
Sprint Running ◽  
Aerobic Process ◽  
Positive Effect ◽  
Experimental Group

Endurance in sprint running is determined by the runner's ability to maintain maximum high speed at a distance and resist its decline due to fatigue that occurs during running. At present, recommendations for the development of sprint endurance are mainly intended for athletes using various means and methods of sports training. The development of this quality in athletes with the use of nutritional improvement technology has mainly general recommendations. Thanks to the nitrate contained in beets, the body absorbs more oxygen and fatigue less during exercise, contributing to the aerobic process. The main task of our work was: to determine the indicators of endurance in sprint running (repeated running of 100 m segments 5-6 times with the determination of the average), and to substantiate the methodology for the development of this quality in athletes using the technology of taking probiotics. The experimental data made it possible to reveal the effectiveness of the applied methodology for the development of endurance in sprint running. Moreover, the greatest effect was achieved using the method of circular training, with the inclusion of the means of speed-strength training in combination with running, as well as repeated running of short and long segments (30-200 m), alternating in one lesson, with a gradual decrease in the rest intervals. The experimental group that took beet juice showed a higher endurance increase in an average of 0.5 seconds than the control group, which allows us to draw a conclusion about the importance of taking nitrate in beets and its positive effect on the endurance of sprinters.

scholarly journals The effect of a formulation based on maduramycin and nicarbazine on rats and broiler chickens in a subacute experiment

2021 ◽  
pp. 41-48
Author(s):  
Roman Dotsenko ◽  
Maryna Romanko ◽  
Yevheniia Vashchyk ◽  
Andriy Zakhariev ◽  
Andrii Zemlianskyi ◽  
...  
Keyword(s):  
Body Weight ◽  
Biochemical Parameters ◽  
Broiler Chickens ◽  
Clinical Signs ◽  
The Body ◽  
Male Rats ◽  
Control Group ◽  
White Rats ◽  
Group I ◽  
Hematological And Biochemical Parameters

The aim: to determine the effect of a preparative form of an antiemeric agent based on maduramycin and nicarbazine on the body of white rats and broiler chickens under the conditions of a subacute experiment. Materials and methods. The formulation based on maduramycin and nicarbazine was administered to rats and broiler chickens with feed for 28 days. One control and three experimental groups were formed for the experiment: Group I – animals received a complete diet without admixture of the formulation (control group), Group II – animals that were administered the formulation (by the amount of active substances) at a dose of 5.0 mg / kg, III – 25.0 mg / kg and IV – 50.0 mg / kg of feed, respectively. In order to establish the toxic effect of the formulation on the body of experimental birds on 7, 14, 28 days of the experiment and 7 days after discontinuation of the formulation, 5 heads from each group were killed under light ether anesthesia, blood samples were taken for hematological and biochemical studies. Results. During the study of the general clinical condition of rats and broiler chickens of the experimental groups, no significant changes in behavior and appearance were detected, compared with the control. Hematological parameters of broiler chickens it was found that the receipt of the formulation with feed at doses of 5, 25 and 50 mg/kg body weight, causes a decrease in hemoglobin and an increase in hematocrit in broiler chickens on day 7 of the experiment. It was found that the changes are reversible, on the 28th day of the experiment the value of these indicators was within the physiological norm. In the study of hematological and biochemical parameters of rats, it was found that the receipt of the formulation with food in doses of 25.0 and 50.0 mg/kg for 28 days, causes a decrease in hemoglobin and increase hematocrit, total protein, albumin, creatinine and urea in male rats on the 7th day of the experiment. Conclusions. Under conditions of repeated oral administration of the preparation mixture to rats and poultry at doses of 5, 25 and 50 mg/kg body weight in the absence of clinical signs of poisoning, insignificant fluctuations in hematological and biochemical parameters were identified

Influence of increased doses of fenbendazole supramolecular complex on sheep’s organism

2018 ◽  
Vol 12 (2) ◽  
pp. 46-52 ◽  
Author(s):  
A.I. Varlamova
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Biochemical Parameters ◽  
Negative Influence ◽  
Supramolecular Complex ◽  
Control Group ◽  
Blood Cell Count ◽  
Russian Scientific ◽  
Russian Scientific Research Institute ◽  
Hematological And Biochemical Parameters

The purpose of the research: study of the influence of increased doses of fenbendazole supramolecular complex (FSMC) on sheep’s organism. Materials and methods. The experiment was carried out at the Podolsk Department of All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K. I. Skryabin on 20 manorial invasion-free sheep aged 2-3 years old. Animals were divided according to the principle of analogues into 4 groups, 5 heads in each group. Animals of the 1, 2 and 3 group were orally administered with FSMC given as a single dose of 2, 6, 10 mg/kg, respectively, according to the active substance, i.e in therapeutic and in a dose increased by 3 and 5 times. Sheep of the fourth group didn’t receive the drug and they were as control. Study of clinical, hematological and biochemical parameters of animals from all groups was conducted 1 day before and in 1, 3, 5 days after administration of the drug by means of standard methods. Results and discussion. FSMC in therapeutic dose as well as in a dose increased by 3 and 5 times doesn’t have negative influence on clinical, hematological and biochemical parameters of the sheep. State of the sheep, which received the drug in doses of 20, 60, 100 mg/kg, was within the physiologically normal state and didn’t differ from the state before administration of the drug and from the animals of the control group. Drug security index exceeds 5. Red blood cell count, white blood cell count, hemoglobin count, leukogram parameters as well as biochemical parameters of blood: activity of alkaline phosphatase and amylase, bilirubin, creatinine, urea and glucose counts were within normal limits and didn’t differ from the parameters of the control animals.

The influence of probiotic drug Biolax-U on morphological and biochemical parameters of blood in cows

2020 ◽  
pp. 70-76
Author(s):  
A. Farkhutdinova
Keyword(s):  
Biochemical Parameters ◽  
Hematological Parameters ◽  
Experimental Studies ◽  
Positive Influence ◽  
Biologically Active ◽  
Feed Consumption ◽  
Control Group ◽  
Animal Blood ◽  
Black And White ◽  
White Breed

The expediency of using the probiotic drug Biolax-U in the rations of lactating and dry cows of Black-and-White breed has been studied and scientifically proved. The influence of this drug on the morphological and biochemical parameters of animal blood has been determined. The composition of the probiotic drug Biolax-U consists of eight strains of a balanced complex of living lactic acid bacteria, yeast and actinomycetes, as well as biologically active substances. For experimental studies conducted on 2 groups of cows have been selected by the method of pairs-analogs, the influence of feeding of feed have been prepared with the use of the microbiological drug with probiotic action Biolax-U on feed consumption, morphological and biochemical changes in blood has been studied. Analysis of the rations of cows indicates that the content of calcium, phosphorus, magnesium, sulfur and trace elements such as manganese, copper, zinc and cobalt in the feed has been reduced. It has been found by studies that the use of probiotic drug Biolax-U had the positive influence on the feed intake, digestibility and better assimilation of feed nutrients and contributed to the improvement of blood morphological and biochemical parameters. For example, in animals of the experimental group hemoglobin has increased by 3,6 % (Р < 0,05), red blood cells by 10,1 (P ≤ 0,05), the content of leukocytes by 4,43, carotene by 9,6, glucose by 3,4; reserve alkalinity by 15,6, calcium by 19,4 (P ≤ 0,01), and phosphorus by 18,4 % compared with the control group of animals. During the lactation significantly improved hematological parameters including alkalinity reserve by 5,11 %, calcium level by 11,1, phosphorus by 8,6, hemoglobin by 14,2 %, the content of erythrocytes by 12,3, leukocyte by 3,86, and carotene 11,1 % against the parameters of animals of control group. The improvement of morphological and biochemical parameters of blood of cows indicates about stimulating effect on hematopoiesis and the general clinical condition of animals that contributes to the improvement of metabolic processes when using feed prepared with the use of microbiological drug with probiotic action Biolax-U.

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