scholarly journals Safety of using the preparation “Licopid®” in opinion of experts in various specialities

2019 ◽  
Vol 36 (2) ◽  
pp. 81-92 ◽  
Author(s):  
A. E. Krasheninnikov ◽  
A. V. Matveev ◽  
T. M. Andronova ◽  
S. V. Guryanova ◽  
N. V. Shilova ◽  
...  

Aim. To study the safety of the preparation “Licopid®” using the data, obtained with the method of questioning of doctors of various specialities. The reactant of “Licopid®” tablets is glucoseminylmuramildipeptide – a synthetic analogue of the structural fragment of bacterial cells membrane (peptidoglycan), which is an activator of congenital and acquired immunity;it strengthens the defense of the body from viral, bacterial and fungal infections; it has an adjuvant effect in development of immunological reactions. Materials and methods. The object of this study were the answers of 2315 specialists to the questions of surveys regarding the safety of using immunomodulator“Licopid®” in their practical activity. The regions, involved into the survey were the following cities: Moscow, Kazan, Krasnodar, Ekaterinburg, St. Petersburg, Chelyabinsk, Novosibirsk, Perm, Samara and Voronezh as well as Krasnodar Krai. Processing of the results was fulfilled with the methods of descriptive statistics; the obtained data were compared with the method based on calculation of chi-square criterion. Results. The analyzed results showed that 962 respondents (41.5 %) indicated the fact of revealing undesirable reactions (UR) of the preparation “Licopid®” in their own practice. It was noted by them that all undesirable reactions were not severe and predicted, i.e. they were indicated in the instruction for medical use of “Licopid®” 1 mg and 10 mg. Conclusions. While conducting questioning, the authors revealed statistically significant differences in the structure of respondents’ answers depending on the region of residence and medical speciality. At the same time, for all UR, indicated in instruction, subjectively estimated occurrence rate of reactions coincided with that, declared upon registration, except myalgias and arthralgias, which were noted by doctors much rarely.

2013 ◽  
Vol 31 (4) ◽  
pp. 437-443 ◽  
Author(s):  
Dartagnan Pinto Guedes ◽  
Francisléia Nascimento Almeida ◽  
Jaime Tolentino M. Neto ◽  
Maria de Fátima de M. Maia ◽  
Thatiana Maia Tolentino

OBJECTIVE: To assess the prevalence of low body weight/thinness, overweight and obesity in a representative sample of children and adolescents from a Brazilian region with low economic development. METHODS: A total of 982 girls and 986 boys, aged seven to 17 years old and assisted by Segundo Tempo Program, from Montes Claros, Minas Gerais, Brazil, were included in the study. Low body weight/thinness, overweight and obesity were defined based on body mass cut-off indexes recommended by the International Obesity Task Force. The prevalence of the nutritional status according to sex and age was compared by chi-square test. RESULTS: In girls, the frequency of low body weight/thinness, overweight and obesity was 4.1, 18.4 and 3.8%, respectively; in boys, these percentages were 6.3, 13.2 and 2.9%, respectively. The low body weight/thinness for girls raised from 2.7% (7-10 years old) to 5.5% (15-17 years old); the body weight excess (overweight and obesity) decreased from 30.1 to 16.2% for the same age groups. In boys, the corresponding trends were from 3.2 to 9.4% for low body weight/thinness, and from 23.4 to 9.2%, for body weight excess. CONCLUSIONS: The data indicate that, even in a region with low economic status, the body weight excess was the main problem associated with nutritional health. The high overweight and obesity prevalence rates indicate the need of public policies for promoting healthy feeding behaviors and physical activity.


2018 ◽  
Vol 10 (10) ◽  
pp. 3615 ◽  
Author(s):  
Yoonjeong Jeong ◽  
Seweryn Zielinski ◽  
Ji-soon Chang ◽  
Seong-il Kim

This study aims to compare motivation-based and motivation-attitude-based segmentation of tourist markets, by identifying the heterogeneity of both solutions. A k-means cluster analysis was conducted to segment markets, using the data collected from 722 respondents, via an onsite survey of visitors to the Kuang Si Waterfall and Konglor Cave in Lao People’s Democratic Republic. Subsequently, socio-demographic and trip-related characteristics among the segments were compared using ANOVA and Chi-square tests. Both motivation-based and motivation-attitude-based segmentation each generated four distinctive segments. Although both solutions are viable for segmentation, the latter was found to be more useful in separating segments than the former, as its segments were significantly more distinguishable from each other in terms of socio-demographic and trip-related characteristics. This result contributes to the body of research on the comparison of market segmentation techniques, which is a rarely investigated topic.


2020 ◽  
Vol 7 (2) ◽  
pp. 95
Author(s):  
Rini Hariani Ratih

ABSTRAK Data Riskesdas 2018 menunjukkan bahwa 25,7% remaja usia 13-15 tahun dan 26,9% remaja usia 16-18 tahun dengan status gizi pendek dan sangat pendek. Selain itu terdapat 8,7% remaja usia 13-15 tahun dan 8,1% remaja usia 16-18 tahun dengan kondisi kurus dan sangat kurus. Sedangkan prevalensi berat badan lebih dan obesitas sebesar 16,0% pada remaja usia 13-15 tahun dan 13,5% pada remaja usia 16-18 tahun. Data tersebut merepresentasikan kondisi gizi pada remaja di Indonesia yang harus diperbaiki. Berdasarkan baseline survey UNICEF pada tahun 2017, ditemukan adanya perubahan pola makan dan aktivitas fisik pada remaja. Gizi merupakan salah satu faktor utama penentu kualitas hidup dan sumber daya manusia. Tujuan penelitian Untuk mengetahui hubungan perilaku makan terhadap status gizi pada siswi SMAN 2 Tambang 2018. Penelitian ini mengunakan jenis kuantitatif analitik dengan desain cross sectional.  Populasi pada penelitian ini adalah seluruh siswa putri SMAN 2 Tambang dari kelas XI sebanyak 240 orang  dengan sampel sebanyak 71 orang. Hasil uji Chi Square didapatkan nilai p=0,01 (≤ 0,05. Ada hubungan yang signifikan perilaku makan dengan status gizi pada remaja putr di SMAN 2 Tambang.Kata Kunci : perilaku makan; status gizi;  remaja putri  RELATIONSHIP BETWEEN EATING BEHAVIOR WITH NUTRITIONAL STATUS IN FEMALE ADOLESCENT AT TAMBANG STATE SENIOR HIGH SCHOOL 2 ABSTRACT  According to the report of Indonesian Health Research in 2018 showed that 25.7% of adolescents aged 13-15 years and 26.9% of adolescents aged 16-18 years have a short and very short nutritional status. In addition, there were 8.7% adolescents aged 13-15 years and 8.1% adolescents aged 16-18 years with thin and very thin conditions. Meanwhile, the prevalence of overweight and obesity was 16.0% in adolescents aged 13-15 years and 13.5% in adolescents aged 16-18 years. Nutrition is one of the main factors determining the quality of life and human resources. Nutrients are chemicals found in food that the body needs to maintain health and immunity; adolescents are one of the groups that are prone to experiencing nutritional problems. The research objective was to determine the relationship between eating behavior and the nutritional status of students at SMAN 2 Tambang 2018. This research method used a quantitative analytic research type, with a cross sectional study design. The populations in this study were all 12 students of Tambang State Senior High School 2 from class XI totaling 240 students. The sample in this study was some of the 71 class students. The results of the Chi Square test showed that the value of p = 0.01 (≤ 0.05), this means that statistically there is a relationship between eating behavior and nutritional status in young girls. Keywords: eating behavior; nutritional status; female adolescent


2020 ◽  
Vol 11 (2) ◽  
pp. 86-93
Author(s):  
Alvia Anggreini Setyaningrum ◽  
Sri Adiningsih

Overweight is an accumulation of excess adipose reserve within the body, resulting in an increase of bodyweight. Consumption of ultra-processed beverages, and energy intake from food and beverage are several fators that can cause the problem of overweight. This research aims to understand the relation between sugar intake in ultra-processed beverages and energy intake from food and beverages with overweight among teenage students of senior high school 6 Surabaya. The research is an observational research with cross-sectional design. Sampling is taken using proportional random sampling technique. The number of participants are 80 teenagers from 10th and 11th classes in June 2020. Participants are aged 15-18 years old. Energy intake from food and beverages are taken from 2x24 hour recall questionnaire, and sugar intake from ultra-processed beverages taken from seven-day beverages diary.. Statistical analysis are done using chi-square. The result shows relation between energy intake from food and beverages with overnutrition, with (p =< 0,001). In conclusion, excess energy intake from food and beverages relation with overweight problem to teenagers, thus requiring balanced nutritional guide education as well as annual nutrition status monitoring, from the school to its teenage students.  


2018 ◽  
Vol 1 (1) ◽  
pp. 046
Author(s):  
Yusni Podungge ◽  
Puspita Sukmawaty Rasyid

Undernutrition in infants is a condition where the baby does not growand develop optimally because of the unfulfilled intake of nutritionsubstances in the body. Under-nutrition in infants can be overcome bythe provision of balanced nutritious foods, one sign of improvednutrition can be seen from normal weight gain for age. One of the foodsthat can boost the improvement of nutrients is a food that containsproteins and vitamins, such as yellow pumpkin and chicken, whereyellow pumpkin contains vitamin A and chicken meat as a source ofanimal protein that contains good nutrients. The purpose of this studywas to analyze the effect of yellow pumpkin and chicken meat onweight growing infant 12 months in work area of Talaga JayaCommunity Health Center. The research method used experimentalresearch model with design non equivalent control group for eachgroup of intervention and control. Sampling using purposive samplingaccording to inclusion and exclusion criteria. With a sample number of30 malnourished infants less than 12 months of age. Analyticaltechniques was used in the chi square test. The result of this researchwas showed that value of chi square count 22,634 highger than chisquare table Df 1 = 3,841. There was influence giving yellow pumpkinpumper and chicken to enhancement nutritional weight infant weight12 month in work area Puskesmas Talaga Jaya. The conclusion wasthe provision of pumpkin porridge can raise the weight of infants lessthan 12 months of age as a benchmark nutritional improvements ininfants less nutrition.


Author(s):  
Aprilia Aprisanti Reyani

Latar Belakang :Kehangatan dada ibu dapat menghangatkan bayi, sehingga apabila bayi diletakan di dada ibunya segera setelah melahirkan atau dilakukan Inisiasi Menyusu Dini, dapat menurunkan resiko hipotermia dan menurunkan kematian bayi baru lahir akibat kedinginan atau hipotermia. Tujuan : Tujuan dari penelitian ini adalah untuk mengetahui perbedaan suhu tubuh bayi baru lahir antara bayi yang berhasil melakukan IMD dan bayi yang tidak berhasil melakukan IMD Metode  :Analitik,desain cross sectional,populasi semua bayi baru lahir, sampel bayi barulahir, teknik Non Random Sampling, pengumpulan data dengan menggunakan Lembar Observasi dengan menggunakan uji Chi-Square dengan nilai signifikan α = 0.05 yaitu bila hasil uji statistik menunjukan p ≤ α maka H0 ditolak. Hasil      :Suhu tubuh bayi baru lahir yang berhasil melakukan IMD sebagianbesardengansuhutubuhtidakhipotermisebanyak 20 bayi (87%) Suhu tubuh bayi baru lahir yang tidak berhasil melakukan IMD sebagianbesardengansuhutubuhhipotermisebanyak 8 bayi (66,7%). Dari hasil uji statistik diperoleh hasil nilai p = 0,005 < α = 0.05 maka H1 diterima, artinya ada Perbedaan suhu tubuh bayi baru lahir yang berhasil melakukan IMD dan yang tidak berhasil melakukan IMD Kesimpulan :Terdapat perbedaan suhu tubuh bayi baru lahir antara bayi yang berhasil melakukan IMD dan bayi yang tidak berhasil melakukan IMD.   Kata kunci : Inisiasi Menyusu Dini, Suhu Tubuh Bayi Baru Lahir                                                                                               THE DIFFERENCE BODY TEMPERATURE BETWEEN BABIES WHO SUCCESSFULLY INITIATE BREASTFEEDING EARLY AND BABIESWHO FAIL TO INITIATE EARLY BREASTFEEDING AT RSIA KIRANA SIDOARJO 2019  Background : The warmth of the mother’s chest can warm the baby, so that when the baby is in the mother’s breast immediately after birth or initiated early breastfeeding can reduce the mortality rate of newborns due to hypotermia.Purpose :the purpose of this study was to determine the difference in body temperature of newborns between infants who successfully initiated early breastfeeding and infants who did not succeed in initiating early breastfeedingMethods : analytical, cross sectional design, population 40 newborns, samples 35 newborns, Non Random Sampling techniques, the data accumulation using observation sheets and using chi-square test, with significant value α = 0.05 is when the statistical test results show p ≤ α then Ho is rejected.Result : The body temperature of the newborn who succeeded in initiating early breastfeeding was 36.78ºC with 23 (65.7%) of infants none having hypothermia, the newborn baby's body temperature that did not succeed in doing this early breastfeeding was 35.78ºC With 8 infants experiencing hypothermia, while 4 babies with normal temperature. From the results of statistical tests obtained results with the value p = 0,000 <α = 0.05 then H1 accepted, meaning there is a difference in body temperature of a newborn who successfully initiated early breastfeeding and who did not succeed in Early Breastfeeding Initiation. Conclusion : There is a difference in the body temperature of a newborn between infants who successfully initiated breastfeeding and infants who are not successful in initiating early breastfeeding....Keywords : Early breastfeedinginitiation, newborns temperature


2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Ashwag Yagoub Aloyouny

Introduction. Palatine tonsils are part of the mucosa-associated lymphoid tissue, located in the oropharyngeal region. Although these tissues protect the body from foreign intruders, they are more prone to infections due to their anatomical structure and location. For instance, the differential diagnosis of a white lesion on the palatine tonsil can range from benign to malignant lesions. Oral lymphoepithelial cysts commonly arise as painless, yellowish nodules on the floor of the mouth and the ventral or lateral surface of the tongue. Case Presentation. This paper presents a rare case of an unusual site of a lymphoepithelial cyst (LEC) in the oral cavity. The lesion was located in the tonsil of a 20-year-old woman with a chief complaint of a painless, white lump in the back of the mouth for nine months. Discussion. The differential diagnosis of a white lesion on the palatine tonsil is caused by several factors, such as bacterial, viral, and fungal infections; trauma; stones; cysts; abscess; or cancer. In this case, both the clinical presentation and extra- and intraoral examinations were highly associated with LEC. Oral LEC etiopathogenesis is uncertain, and several theories have been proposed to discuss the causes of LEC. In addition, oral LEC could be monitored without surgical intervention if the nodule is asymptomatic. Conclusion. We emphasize the importance of a thorough clinical examination of oral and oropharyngeal lesions, which are usually neglected.


2020 ◽  
Vol 34 (4) ◽  
pp. 361-366
Author(s):  
Edcleide Oliveira dos Santos Olinto ◽  
Gina Araújo Martins Feitosa ◽  
Izaura Odir Lima Gomes da Costa ◽  
Janine Maciel Barbosa ◽  
Ericka Vilar Bôtto Targino ◽  
...  

Introduction: There is a strong relationship between malnutrition and increased length of hospitalization and morbidity and mortality. Studies have shown that malnourished patients can have up to twenty times more complications than eutrophic ones. In critically ill patients, there is a tendency to catabolism, resulting in the loss of lean body mass, which when it reaches 40% is usually lethal. Methods: A quantitative, descriptive study was conducted on adults from both genders, admitted to the intensive care unit (ICU) of a university hospital, from March to December 2018. The following variables were collected from the evaluation and nutritional records: length of hospitalization in the ICU, date of discharge or death, nutritional risk through specific screening, height, weight and arm circumference (AC). For the screening, the Nutric score was used. For the nutritional evaluation, the body mass index (BMI) and AC indicators and the classifications recommended by the World Health Organization (2004) and Blackburn and Thornton (1979) were used. After collecting the data, they were analyzed in the Statistical Package for Social Sciences (SPSS) 13.0 and for the association of the variables the Chi-square test was used, considering statistical difference when the p value <0.05. Results: The sample consisted of 116 patients, mostly female (53.4%) whose median age was 46 years (interquartile range IQR 31-53). Regarding the frequency of nutritional risk, most patients (61.5%) had a low score. There was an important frequency of malnutrition, according to the AC indicator (73%), although BMI (43.5%) showed eutrophy. Even though most patients had low nutritional risk, those with high nutritional risk (38.5%) had a higher tendency to mortality, however, not statistically confirmed (p> 0.05). There was also a tendency of association between death and malnutrition, although no statistical significance was shown(p> 0.05). Conclusion: Patients at nutritional risk and/or malnutrition appear to be vulnerable to worse clinical outcomes.


1937 ◽  
Vol 33 (7) ◽  
pp. 829-835
Author(s):  
I. I. Shimanko

The question of the relationship between the allergic process and the skin is one of the oldest questions in the theory of allergy. The participation of the skin in allergic processes affects both the development of various forms of diseases, inherently allergic, and the possibility of getting on the skin with allergic forms of syphilis, TBK, fungal infections, eczema, as well as with allergic processes in other organs - one or another biological reactions, indicating a general allergic restructuring of the body.


2017 ◽  
Vol 3 (1) ◽  
pp. 52
Author(s):  
Lidia Widia

Immunization is a process to make the body's immune defense system against invading microorganisms (bacteria and viruses) that can cause infections before these microorganisms have a chance to invade our bodies. Hepatitis B immunization is the immunization to prevent the body less susceptible to hepatitis B virus. The purpose of this study was to identify whether there is the Relationship Between Hepatitis B Immunization Status Completed At Age 0-6 Month With Events Hepatitis B in the Work Area Puskesmas Perawatan Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu.This research method is analytical survey and cross sectional approach for studying the dynamics of the correlation between risk factors and the effects of the approach, observation or data collection at once at a time (point time approach), the sampling technique is taken with total sampling technique that met the inclusion criteria and exclusion of mothers with babies were recorded in the register Puskesmas Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu. The data obtained were analyzed using chi-square test with significance of 0.05. Chi-Square test results obtained there is a significant relationship between the completeness status of hepatitis B immunization (P = 0.005) with the occurrence of Hepatitis B, for the conclusion in this study found no relationship between the completeness status of hepatitis B immunization with Hepatitis B in Puskesmas Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu. It is hoped that no more infants are immunized against the completeness of incomplete hepatitis B immunization to reduce the incidence of hepatitis and reduce infant mortality


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