scholarly journals Mucormycosis (the black fungus) during COVID-19 pandemic: growing concerns of immunosuppressive therapy and uncontrolled diabetes mellitus

Author(s):  
M. Tanvir Islam ◽  
Masuda Parvin ◽  
Morshed Nasir

In recent days rare but aggressive fungal disease in the form of mucormycosis has emerged and become a health concern mostly for the patients suffering from severe COVID-19 infection, poorly controlled diabetes mellitus, and patients who receive immunosuppressive therapies for diseases like malignancies. Many studies have demonstrated the relationship between COVID-19, immunosuppressive therapies, diabetes mellitus, and mucormycosis. In diabetes mellitus, poor glycemic control allows the fungi to produce pathogenesis. On the other hand, immunosuppression causes compromised neutrophil function that inhibits phagocytosis and the fusion of phagolysosome. Epidemiological data has proved that the incidence of mucormycosis from a global perspective has been on the rise and it has an association with an increasing number of diabetic cases in the world. In countries like India, Nepal, and Bangladesh where the number of diabetic and cancer patients has been growing constantly, mucormycosis could be a serious health concern in near future. Much more scientific studies, statistical analysis, and engagement of health experts are needed to combat the situation.

2021 ◽  
pp. 0261927X2110263
Author(s):  
David M. Markowitz

How do COVID-19 experts psychologically manage the pandemic and its effects? Using a full year of press briefings (January 2020–January 2021) from the World Health Organization ( N = 126), this paper evaluated the relationship between communication patterns and COVID-19 cases and deaths. The data suggest as COVID-19 cases and deaths increased, health experts tended to think about the virus in a more formal and analytic manner. Experts also communicated with fewer cognitive processing terms, which typically indicate people “working through” a crisis. This report offers a lens into the internal states of COVID-19 experts and their organization as they gradually learned about the virus and its daily impact.


2017 ◽  
Vol 2 (1) ◽  
pp. 5
Author(s):  
Ludiana Ludiana

Diabetes mellitus is a chronic metabolic disorder marked increase in blood glucose. According to the World Health Organization (WHO) in 2013 the incidence of diabetes mellitus in the world reached 347 million people in Indonesia alone ranks among the seven countries with the highest diabetes prevalence of 7.6 million people. Among the causes of the increase in blood glucose levels in diabetics is due to psychological factors, namely anxiety. In the pre-survey results in Puskesmas Sumbersari Bantul note that from 8 patients with diabetes mellitus, there are 6 people experiencing anxiety and 2 do not complain any signs of anxiety. The purpose of this study was to determine the relationship of anxiety with blood glucose levels of diabetics mellitus in Puskesmas Sumbersari Bantul District of South Metro City. The type quantitative research, form design used is cross sectional. The population in this study are patients with diabetes mellitus in Puskesmas Sumbersari Bantul District of South Metro totaling 408 samples taken as many as 41 people. The analysis in this study using the test Person Product Moment. Statistical analysis showed that anxiety patients with diabetes mellitus are at an average score of 27.44 with a standard deviation of 4.353 and the average blood sugar levels of people with diabetes mellitus are at 339.78 mg / dL with a standard deviation of 74.742. In the Person Product Moment test results proved no relationship anxiety with blood sugar levels of people with diabetes mellitus (p-value = 0.000 <a 0.05). Pearson correlation results obtained value of 0.817 towards a positive correlation with the strength of the relationship is very strong. Conclusions research shows there is an anxiety relationship with blood glucose levels of diabetics mellitus.


2018 ◽  
Vol 5 (1) ◽  
pp. 3404-3406
Author(s):  
Fernando Silalahi Marshal, ◽  
Doddy Prabisma Pohan ◽  
Aznan Lelo

Background : Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to insulin secretion abnormalities, insulin work or both. Most Diabetes Melitus treatments are always associated with diabetic ulcers. Death rates and amputation rates are still high, respectively at 32.5% and 23.5%. The fate of patients with post-amputation Diabetes Melitus is still very bad, as many as 14.3% will die within a year after amputation and 37% will die 3 years after amputation. It has been  mentioned in previous clinical studies that uncontrolled diabetes mellitus was associated with elevated HbA1c  levels associated with the development of retinopathy as well as other complications, with a research reference value r = 0.079. Methods : The study involved Diabetes Melitus patients with diabetic foot diagnosis in Thoracic, Cardiac, and  Vascular  Surgery Polyclinic Department of Surgical and Inpatient Surgery RSUP H. Adam Malik Medan  period  January 2014- December 2016 with a total sample of 70 people. Result : The mean age of study subjects was 55.65 + 12.25. In the table shows that the study subjects based on the most gender were men with 47 subjects (67%). The mean of Glycosilated hemoglobin (HbA1c) was 6.4 + 2.44 mg / dL with the most patients found  at HbA1c <7 mg / dL level of  49 patients (70%). The result of the analysis is p = 0.0001 (p <0,05) this means there is significant relation between Glycosilated hemoglobin (HbA1c) and diabetic foot. Also obtained OR = 3.1 (CI = 95%, p <0.05). Conclusion: Bivariatically there was a significant correlation between Glycosilated hemoglobin (HbA1c) and diabetic foot with p = 0.0001 and Odd Ratio of OR = 3,1 (CI = 95%, p <0,05). For the mean result of Glycosilated hemoglobin (HbA1c) was 6.4 + 2.44 mg / dL with the highest HbA1c <7 mg / dL of 49 patients (70%).


ORL ro ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 18-20
Author(s):  
Blebea Cristina Maria ◽  
Ujvary Laszlo Peter ◽  
Dindelegan Maximilian George ◽  
Violeta Necula ◽  
Alma Maniu

Longevity is expected to rise in the following years, therefore neurological problems become a global health concern. Dementia and hearing loss are highly prevalent pathologies in the older population, and a possible association be­t­ween them was studied in recent years. Dementia is still con­si­dered an incurable disease, but the evolution of the symp­toms is considered manageable by addressing the risk factors. In the latest studies, hearing loss has been con­sidered a modifiable risk factor for cognitive decline, along with obesity, smoking, hypertension, depression and physical inactivity. This paper presents the potentially pi­vo­tal role hearing loss might have in the evolution of cog­ni­tive decline and a summary of studied theories regarding the relationship between these pathologies. The recent guide­line of the World Health Organization regarding cognitive de­cline management involves otolaryngologists in the ef­fort of improving outcomes.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 225
Author(s):  
Yun Jin Kim ◽  
Linchao Qian ◽  
Muhammad Shahzad Aslam

Cyberbullying behaviour is an international public health concern all around the world due to the increasing trend of working from home during COVID-19. The prevalence of workplace cyberbullying behaviour (WCB) has been shown to be increased prior to COVID-19 among allied health professionals, such as nurses and trainee doctors. There has been a lack of bibliometric analysis on scientific publications concerning this subject; therefore, the current articles presents a protocol for bibliometric analysis of WCB. An indicator-based search will have carried out from documents on PubMed and Scopus to retrieve data from primary peer-reviewed WCB research articles using relevant keywords. Articles that involve WCB research will be included in the analysis. The dataset will identify documents all around the world, and data will be validated using the VAKS assessment tool. Analysis will be carried out by comparing the relationship among institutions, authors, countries and keywords. The dataset will be publicly accessible in the Zenodo repository. There will be no involvement of human participants; therefore, the current research does not require an ethical review.  Results will be publish in a peer-reviewed journal and at related conferences


2019 ◽  
Vol 3 (3) ◽  
pp. 99-109
Author(s):  
Qutaibah Mohammad Oudat ◽  
Muhammad Alqudah ◽  
Deena Ababneh

The interest in studying the microbial gut like probiotics has increased because it may play a significant role in reducing the risk of certain health conditions and promote overall health. In the recent decade, the nutritional researches have linked between having a regular healthy diet and the health conditions during pregnancy. For example, during the pregnancy period, women may counter several health conditions, such as Gestational Diabetes Mellitus (GDM) level. In this relation, a few recent researches have suggested that having a rich diet with a probiotics/prebiotic may reduce the incidence of GDM. Therefore, in the world market, the interest in studying the correlation between probiotics/prebiotics and the incidence of pregnancy health conditions has increased. This paper has been designed to review the recent studies that investigated the relationship between a rich diet with probiotics/prebiotics and the gestational health conditions.


Author(s):  
N.G. Barnov ◽  
V.V. Shchiptsov

Information on the International Genetic Classification of Noble Corundum is given. The scheme of location of the main deposits and occurrences of ruby-bearing complexes of the world is attached: 1 – magmatic; 2 – metamorphogenic; 3 – sedimentary (residual ancient crusts of chemical weathering, alluvial and dealluvial-alluvial placers). The location of ruby objects is shown, including the largest areas of depleted, currently operating and promising for the near future ruby deposits in 36 countries around the world. The main typological features of rubies are described. It is emphasized that all properties of rubies are determined by their primary indigenous origin. The typology of rubies is based on the principles of the relationship between magmatism and metamorphism in the formation of the groups under consideration. Hydroblasting and selective crushing methods for mining of corundum-bearing complexes are characterised. The trend towards increased research into the commercial exploitation of the primary sources of ruby-bearing complexes is highlighted. In countries with highly developed mining industries, underground mining is the main way to extract gemstones.


Author(s):  
Rafael Brito-Aguilar

Dementia has become a major public health concern around the world. Dementia risk factors are significantly different among countries. The number of new cases of dementia anticipated each year worldwide is almost 7.7 million, one new case every four seconds. There are 3.6 million (46%) new cases per year in Asia, 2.3 million (31%) in Europe, 1.2 million (16%) in the Americas, and 0.5 million (7%) in Africa. Latin American and Caribbean low and middle-income countries are at high risk. Air pollution is an important risk modifiable factor for dementia across the world, and the recent report of the Alzheimer’s disease continuum in children and young adults residing in Metropolitan Mexico City along with the presence of cognitive impairment in 55% of the young adult population residing in Mexican cities with fine particulate matter concentrations above the current USEPA annual standard of 12 μg/m3 makes this a severe public health problem in progress. It is imperative to keep generating epidemiological data on dementia worldwide and their relationship with air pollutants to improve the strategies to face all the challenges associated with dementia and Alzheimer’s disease in particular. Alzheimer’s disease is a fatal disease, we have no cure, and we ought to invest in protecting our citizens by intervening in modifiable environmental factors.


2020 ◽  
Vol 12 (10) ◽  
pp. e4322
Author(s):  
Wilian Reis Rosário ◽  
Antonio Vicente Vieira De Araujo ◽  
Fernanda Farias Costa ◽  
Ana Cláudia Ribeiro Farias ◽  
Milena Sousa Freitas ◽  
...  

Objective: To evaluate the relationship between metabolic syndrome (MS) and oral health. Methods: This is a bibliographic review with articles available in the PubMed, SciELO, Web of Science, Google Scholar and Portal Periódicos databases, published between 2010 and 2020. The keywords used were metabolic syndrome, oral health, obesity, diabetes, hypertension, periodontitis and caries. Results: MS and oral pathologies are some of the biggest health problems in the world today and tend to increase with the development of countries and with the aging of the population. The literature indicates a close relationship between MS and oral health, mainly associating diabetes mellitus (DM) and periodontitis, obesity and dental caries, cardiovascular disease, and periodontitis. Inflammatory factors and diet are important mediators of these relationships. Conclusion: MS and oral health are associated through the mechanisms of inflammation, the immune system, and the diet. MS can reciprocally aggravate dental caries and periodontitis, as well as oral treatment can assist in the treatment of MS, but there are still controversial results and this relationship should be further clarified.


2019 ◽  
Vol 4 (1) ◽  
pp. 56-81 ◽  
Author(s):  
Francesca Orsini

Abstract “For any given observer,” David Damrosch argued in What is World Literature?, “even a genuinely global perspective remains a perspective from somewhere, and global patterns of the circulation of world literature take shape in their local manifestations.” Within world-system approaches that fix centres, peripheries and semiperipheries, or with approaches that consider world literature only that which circulates transnationally or “globally,” the relativizing import of this important insight remains inert or gets forgotten. As Indian editors and writers in the early decades of the twentieth century undertook more translations of foreign works and discussed the relationship between India and the world, overlapping understandings of world literature emerged in the Indian literary field. This essay explores three different visions of world literature from the same region and period but in different languages – English, Hindi, and Urdu – highlighting their different impulses, contexts, approaches, and outcomes in order to refine our notion of location. And whereas much of the recent debate and activities around world literature has revolved around the curriculum or around publishers’ series and anthologies, in the Indian case exposure to and discussion of literature from other parts of the world took largely place in the pages of periodicals.


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