​Effect of a Polyherbal Additive on Performance and Parasite Infection of Hair Creole Ewes

2021 ◽  
Author(s):  
M.A. Mejia-Delgadillo ◽  
H.A. Lee-Rangel ◽  
P.A. Hernandez-Garcia ◽  
A. Vazquez-Valladolid ◽  
H. Mendez-Cortes ◽  
...  
Keyword(s):  
Production Control ◽  
Anthelmintic Resistance ◽  
Parasitic Infection ◽  
Herbal Product ◽  
Basal Diet ◽  
Gastrointestinal Nematodes ◽  
Positive Control ◽  
Control Group ◽  
Parasite Infections ◽  
High Concentrations

Background: Gastrointestinal nematodes (GIN) infection represents several problems to livestock production. Control of GIN infection is usually achieved by the use of chemotherapeutic anthelmintic drugs. However, indiscriminate use of anthelmintics led to development of anthelmintic resistance. An alternative to chemical control is use of bioactive plants in animal feeds as natural anthelmintics. The objective of this experiment was to compare the effects of polyherbal additive containing high concentrations of saponins with a conventional chemical antiparasitic drug on performance and GIN counts of ewes. Methods: Sixteen hair ewes (creole 19.05±0.895 kg initial BW) fed a basal diet, were randomly assigned to one of three treatments: 1) Doramectin (0.2 mg/kg BW, as positive control); 2) Polyherbal additive, Peptasan (4 grams/lamb/day) and 3) Control group that was not dewormed. The experiment was conducted for 28 days. At 0, 14, 21 and 28 parasite infections were assessed by fecal egg counts (FEC). Result: The daily gain was positively correlated (P less than 0.01) with herbal product (261 g/d) and Doramectin (146 g/d), in contrast with the control group (33 g/d). The number of eggs per gram of feces (EPG) was significantly (P less than 0.01) reduced by Peptasan (90 EPG) compared to Doramectin (711 EPG) after 28 days of treatment. At the same time the EPG in control group was remained unchanged (4566 eggs/g). Infection with GIN can affect feed utilization and lamb performance and polyherbal products are alternative anthelmintics to reduce the parasitic infection in growing ewes.

scholarly journals Cellular and humoral immune responses associated with protection in sheep vaccinated against Teladorsagia circumcincta

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Cynthia Machín ◽  
Yolanda Corripio-Miyar ◽  
Julia N. Hernández ◽  
Tara Pérez-Hernández ◽  
Adam D. Hayward ◽  
...  
Keyword(s):  
Immune Responses ◽  
T Cell Activation ◽  
Cell Activation ◽  
Anthelmintic Resistance ◽  
Gastrointestinal Nematodes ◽  
Control Group ◽  
Sheep Breeds ◽  
Humoral Immune ◽  
Humoral Immune Responses ◽  
Teladorsagia Circumcincta

AbstractDue to increased anthelmintic resistance, complementary methods to drugs are necessary to control gastrointestinal nematodes (GIN). Vaccines are an environmentally-friendly and promising option. In a previous study, a Teladorsagia circumcincta recombinant sub-unit vaccine was administered to two sheep breeds with different levels of resistance against GIN. In the susceptible Canaria Sheep (CS) breed, vaccinates harboured smaller worms with fewer eggs in utero than the control group. Here, we extend this work, by investigating the cellular and humoral immune responses of these two sheep breeds following vaccination and experimental infection with T. circumcincta. In the vaccinated CS group, negative associations between antigen-specific IgA, IgG2 and Globule Leukocytes (GLs) with several parasitological parameters were established as well as a higher CD4+/CD8+ ratio than in control CS animals, suggesting a key role in the protection induced by the vaccine. In the more resistant Canaria Hair Breed (CHB) sheep the vaccine did not significantly impact on the parasitological parameters studied and none of these humoral associations were observed in vaccinated CHB lambs, although CHB had higher proportions of CD4+ and CD8+ T cells within the abomasal lymph nodes, suggesting higher mucosal T cell activation. Each of the component proteins in the vaccine induced an increase in immunoglobulin levels in vaccinated groups of each breed. However, levels of immunoglobulins to only three of the antigens (Tci-MEP-1, Tci-SAA-1, Tci-ASP-1) were negatively correlated with parasitological parameters in the CS breed and they may be, at least partially, responsible for the protective effect of the vaccine in this breed. These data could be useful for improving the current vaccine prototype.

Evaluation of Parasitological Homeopathic Complex in the Control of Gastrointestinal Nematodes in Peripartum Sheep

Homeopathy ◽  
2019 ◽  
Vol 108 (04) ◽  
pp. 248-255
Author(s):  
Poliana Araújo Pacheco ◽  
Michael Nunes Marconato ◽  
Letícia Liepkaln dos Reis ◽  
Luciana Morita Katiki ◽  
Cláudia Cristina Paro de Paz ◽  
...  
Keyword(s):  
Body Weight ◽  
Anthelmintic Resistance ◽  
White Cell Count ◽  
Gastrointestinal Nematodes ◽  
Control Group ◽  
Mean Values ◽  
Fecal Egg Count ◽  
Peripartum Period ◽  
And Control ◽  
Increased Susceptibility

Background The appearance of anthelmintic resistance has made it difficult to control verminosis in sheep, leading to increased research to find alternative nematode control. The use of homeopathy in veterinary medicine has been studied as an alternative for the treatment and control of some diseases. In this study, ewes received an anti-parasitic homeopathic complex medicine during the critical peripartum period of increased susceptibility to nematodes. Methods Three randomized groups containing 16 animals each were assigned as follows: ‘H10’ received 10 g homeopathic complex added to concentrated food per day; ‘H20’ received 20 g homeopathic complex added to concentrated food per day; ‘C’ (control group) did not receive a homeopathic complex. Animals were tested to evaluate the effect of homeopathy on several health parameters during a period of 110 days. Results The parasite that prevailed in the copro-cultures of both treatments throughout the experiment was Haemonchus contortus (78.26%). Packed cell volume averages did not present statistically significant differences between the treatments (24.5, 24.4 and 23.9% to C, H10 and H20, respectively; p < 0.05). For total white cell count, lower mean values ( ±  standard error of mean) were observed for the H20 treatment (5,490.9 ± 0.02/µL; p < 0.05), whereas the H10 (5,919.4 ± 0.02/µL) and control (6,098.5 ± 0.02/µL) presented higher and similar averages (p > 0.05). The values for erythrocytes, monocytes, and lymphocytes did not show differences between treatments (p > 0.05). Body weight was greater in the H10-treated animals compared with control. For the fecal egg count (FEC) of Trichostrongylidae and Strongyloides spp., respectively, the averages of the H20 treatment (1,523.0 and 30.6) were not different from control (1,616.0 and 31.6) and H10 (1,038.0 and 27.6); for Trichostrongylidae, however, H10 presented a lower FEC than the control (p = 0.02). For Cooperia, H10- and H20-treated animals showed FEC reductions of 97% and 98%, respectively. Conclusions H20 treatment in peripartum sheep resulted in greater body weight and lower leukocyte count. H10 was associated with lower FEC for Trichostrongylidae. Both H10 and H20 justify a label of ‘effective anthelmintic’ for Cooperia.

scholarly journals Anthelmintic resistance to cattle gastrointestinal nematodes in selected dairy farms of Mymensingh and Sirajganj districts of Bangladesh

2018 ◽  
Vol 5 (1) ◽  
pp. 87-92 ◽  
Author(s):  
TM Mahibur Rahman ◽  
Anita Rani Dey ◽  
Saiful Islam ◽  
Md Shahadat Hossain ◽  
Md Hasanuzzaman Talukder ◽  
...  
Keyword(s):  
Anthelmintic Resistance ◽  
Dairy Farm ◽  
Dairy Farms ◽  
Treated Group ◽  
Gastrointestinal Nematodes ◽  
Control Group ◽  
The Status ◽  
Correction Table ◽  
Benzimidazole Anthelmintic ◽  
And Control

Correction: Table 1 and Table 2 have were omitted from the PDF in error. They were added to page 89 on 17th May 2018.Anthelmintic resistance (AR) to commonly used dewormers is one of the major world-wide constrain in livestock production. The present study was investigated the status of AR in BAU dairy farm, Mymensingh and Talukder dairy farm, Sirajganj. Faecal egg count reduction test (FECRT) was applied to assess AR in cattle of two dairy farms during January to June 2017. The anthelmintics tested were Albendazole (ABZ), a benzimidazole anthelmintic (Almex®, Square Ltd.) and Ivermectin (IVM) (Vermic®, Techno drugs Ltd.), administered at the doses recommended by the manufacturers. In each farm, cattle were divided into treatment and control (not treated) group based on faecal egg counts (FEC), that is at least 200 eggs/g. At 14 days after treatment, faecal samples were collected for post-treatment FEC, which is compared between treatment and control group. Resistance was defined if there was <95% reduction, with lower 95% confidence limit (CL) <90% in the FEC. AR was present in both the dairy farms involved in this study. The FECRT using ABZ revealed 79.7% (95% CL 87.9, 65.8) reduction and 95.8% (95% CL 98.7, 87.1) reduction of FEC in BAU and Talukder dairy farms, respectively. Also, FECRT using IVM revealed 77.9% (95% CL 97.7, 85.5) and 94.2% (95% CL 97.7, 85.5) reduction of FEC in BAU and Talukder dairy farms, respectively. Our study suggest that AR is present in both selected dairy farms and further extensive studies are required to determine the extent of AR in different cattle farms of Bangladesh.Res. Agric., Livest. Fish.5(1): 87-92, April 2018

scholarly journals Does estimation methods affect on phosphorus equivalence value of phytase for layers and broiler chickens?

2020 ◽  
Author(s):  
Azam Yousefi ◽  
Mojtaba Zaghari
Keyword(s):  
Calibration Curve ◽  
Broiler Chickens ◽  
Basal Diet ◽  
Inorganic Phosphorus ◽  
Positive Control ◽  
Estimation Methods ◽  
Control Group ◽  
Regression Equations ◽  
Deficient Diet ◽  
Layer Hens

SUMMARYTwo experiments were performed for evaluating calibration curve (CC) and comparing negative and positive controls (CNP) as a major method for estimating of phytase phosphorus equivalence for layer and broiler chickens. In the first and second experiments, 360 Hy-line W-36 layer hens and 525 day-old Ross-308 broiler chickens were used in a complete randomized design, respectively. Evaluated methods were setting the two regression equations for NPP-supplemented and phytase supplemented treatments with two sub-methods, include calibration curve (CC) or exclude the amount of phosphorus content of basal diet (CC-BD) in calculation, and exploring enzyme equivalency by comparing phosphorus deficient diet as an negative and supplemented diet by inorganic phosphorus sources as a positive control group (CNP). Experiment one included nine treatments (200, 300, 400 and 500 FTU/kg phytase was added to a phosphorus deficient basal diet contained 0.12% AvP, the rest four treatments were included basal diet supplemented with 0.20, 0.27, 0.35 and 0.43% AvP). Experiment two included seven treatments (a basal P deficient diet contained 0.27% AvP, and two increasing levels of AvP, 0.32 and 0.37%, and four doses of phytase 200, 300, 400 and 500 FTU/kg added to basal diet). Each treatment in the both experiments replicated five times. Results indicated that methods of estimation had a significant effect on phosphorus equivalence estimation (P<0.0001). Fitted regression equations considering P content of basal diet (CC-BD) estimated rational values than those ignore it (CC) (0.161% vs 0.365% and 0.432% vs 0.564% for 500 FTU/kg phytase for broiler chicken and layer hens, respectively) (P<0.0001). On average, among three methods used, CC method had the highest estimated values both in broiler chickens and layer hens (p<0.0001). Regardless of mathematical method, there were different significant values for different strains (layer, 0.381% and broiler, 0.179%) (P<0.0001), but not for different traits served as response criteria (P>0.05). In conclusion, the phosphorus equivalent value of enzyme varies according to the estimation methods and strain. Hence, using matrix values of enzyme for accurate feed formulation depend on a variety of circumstances and decision making requires comprehensive information.

scholarly journals Dietary Supplementation With Xylo-oligosaccharides Modifies the Intestinal Epithelial Morphology, Barrier Function and the Fecal Microbiota Composition and Activity in Weaned Piglets

2021 ◽  
Vol 8 ◽  
Author(s):  
Jiayi Su ◽  
Wanghong Zhang ◽  
Cui Ma ◽  
Peifeng Xie ◽  
Francois Blachier ◽  
...  
Keyword(s):  
Barrier Function ◽  
Basal Diet ◽  
Fecal Microbiota ◽  
Positive Control ◽  
Control Group ◽  
Intestinal Epithelial ◽  
Microbiota Composition ◽  
Weaned Piglets ◽  
Blank Control Group ◽  
Expression Of Genes

The present study determined the effects of dietary xylo-oligosaccharides (XOS) supplementation on the morphology of jejunum and ileum epithelium, fecal microbiota composition, metabolic activity, and expression of genes related to colon barrier function. A total of 150 piglets were randomly assigned to one of five groups: a blank control group (receiving a basal diet), three XOS groups (receiving the basal diet supplemented with 100, 250, and 500 g/t XOS, respectively), as well as a positive control group, used as a matter of comparison, that received the basal diet supplemented with 0.04 kg/t virginiamycin, 0.2 kg/t colistin, and 3,000 mg/kg ZnO. The trial was carried out for 56 days. The results showed that the lowest dose tested (100 g/t XOS) increased (P &lt; 0.05) the ileal villus height, the relative amount of Lactobacillus and Bifidobacterium spp., and the concentration of acetic acid and short-chain fatty acid in feces when compared with the blank control group. In conclusion, dietary 100 g/t XOS supplementation modifies the intestinal ecosystem in weaned piglets in an apparently overall beneficial way.

scholarly journals Quality Characteristics of Beef Patties Fortified with Husk Tomato and the Effect on Tannic Acid-Induced Anaemia in Rats

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Amal N. Al-Kuraieef ◽  
Amal H. Alshawi ◽  
Amnah M. A. Alsuhaibani
Keyword(s):  
Lipid Oxidation ◽  
High Efficiency ◽  
Meat Product ◽  
Basal Diet ◽  
Negative Control Group ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Beef Patties ◽  
Husk Tomato

The study evaluated the properties of beef burgers prepared with different concentrations of husk tomato (HT) powder at levels of 2.5%, 5%, and 10% as a natural source of bioactive compounds and also assessed the effectiveness of the powder in the treatment of anaemia. Rats were classified into the negative control group and anaemic rats that were positive control (untreated) and three treated groups which were fed basal diet had 10% of control beef patties, 2.5% husk tomato beef patties, and 5% HTB groups (CBP, 2.5 HTB, and 5% HTB groups). The obtained results revealed that HT powder is rich in carbohydrates, protein, and fat. The addition of 5% husk tomatoes to burgers decreased the contents of fat and ash and increased fiber and carbohydrates. The addition of 2.5 or 5% husk tomatoes to beef patties gave high scores sensory evaluation. The addition of HT to beef patties reduced lipid oxidation compared to CBP at zero time and after a week of storage. It is concluded that the addition of husk tomatoes increases the quality of the beef burger and has high efficiency in retarding lipid oxidation in the burger. 5% HTB is a functional meat product and could improve the nutritional values and treat iron deficiency anaemia in rats.

scholarly journals Analysis of the productive and immune response of lambs infected with gastrointestinal nematodes and fed with saccharin

2021 ◽  
Vol 14 (2) ◽  
Author(s):  
Roberto González-Garduño ◽  
Luis Matias Silva-Torres ◽  
Glafiro Torres-Hernández ◽  
María Eugenia López-Arellano ◽  
Ever del Jesus Flores-Santiago ◽  
...  
Keyword(s):  
Immune Response ◽  
Repeated Measures ◽  
Anthelmintic Resistance ◽  
Live Weight ◽  
Basal Diet ◽  
Gastrointestinal Nematodes ◽  
Anthelmintic Treatment ◽  
Mean Values ◽  
Randomized Design ◽  
Feedlot Lambs

Objective: Determine the productive and immune response of Blackbelly lambs infectedwith gastrointestinal nematodes (GIN) and fed with saccharin.Design/ methodology/ approach: A total of 18 Blackbelly lambs, with an initial live weight (LW) of 13.9 + 3.2 kg, were randomly assigned to three different treatments (T): T1, anthelmintic treatment + basal diet (CTah); T2, basal diet without anthelmintic treatment (STah); and T3, grazing lambs without anthelmintic treatment (STPS). This experiment followed a completely randomized design with repeated measures over time; mean values were compared using Lsmeans. The parameters evaluated included live weight (LW), fecal egg count per gram (FEC), packed-cell volume (PCV), plasma protein (PP), white blood celldifferential count (LEU), and IgA concentration by ELISA with Haemonchus contortusand Trichostrongylus colubriformis antigens.Results: STah and CTah lambs showed higher FEC (885 ± 142) and LW (29.73 ± 5.06kg). Grazing lambs (STPS) had lower PCV (26.4 ± 0.5%) compared to the STah andCTah lambs (27.4 to 28.4%) due to the high prevalence of H. contortus. The IgAconcentration in grazing lambs ranged from 20.2 to 24.5% of the positive standardserum titer. The feedlot lambs (STah and CTah) showed values close to 5%.Study limitations/ implications: Due to anthelmintic resistance problems, it wasimpossible to maintain grazing lambs free of infection; therefore, this group was notincluded.Findings/ conclusions: Saccharin increases sheep resilience and achieves adequateweight gains in parasitized lambs.

scholarly journals Effects of Dietary Tea Polyphenols on Epigallocatechin Gallate, Catechin, Egg Quality and Production of Gallus domestiaus

2021 ◽  
Vol 25 (01) ◽  
pp. 139-145
Author(s):  
Zhenzhen Fan
Keyword(s):  
Egg Production ◽  
Egg Quality ◽  
Epigallocatechin Gallate ◽  
Basal Diet ◽  
Egg Yolk ◽  
Control Group ◽  
Egg Weight ◽  
Quality Testing ◽  
High Concentrations ◽  
Experimental Group

Effect of dietary tea polyphenol (TP) on the content of epigallocatechin gallate (EGCG), catechin (C) in egg yolk, and impact on egg quality and production was investigated. For this purpose, 315 healthy Gallus domestiaus aged 42 weeks were selected and randomly divided into 7 groups. The experimental group added 0.02, 0.05, 0.09, 0.14, 0.19 and 0.24% TP to the basic diet. The control group (CK) was fed basal diet. After 10, 20 and 30 days, 15 eggs were randomly selected from each group for egg quality testing, and 20 eggs were selected for EGCG and C content test in the yolk. The results showed that in the 0.24% TP group, the content of EGCG in egg yolk was significantly higher than that of CK group and the 0.02, 0.05, 0.09 and 0.14% TP groups (P < 0.05), and reached the highest on the 30th day (19.171μg/g). The content of C in egg yolk was significantly higher than that in CK group and the 0.02, 0.05, 0.09 and 0.14% TP groups (P < 0.05); and reached the highest on 30th day (7.071 μg/g). The egg weight of the 0.14% TP group on the 10th day and of the 0.19% TP group on the 20th day were significantly lower than that of the CK group (P < 0.05); the egg yolk weight of 0.14% TP on the 10th and 20th days were significantly lower than that of the CK group (P < 0.05). On the 30th day, compared with the control group, the egg weight of the 0.14% TP group was significantly reduced (P < 0.05), the egg yolk color of 0.05 and 0.14% TP groups was significantly increased (P < 0.05). During the whole experiment, the egg production of 0.24% TP group was significantly higher than that of control group (P < 0.05). In conclusion, adding high concentrations of TP can increase the content of EGCG and C in the yolk; however, it has a certain impact on egg weight, yolk color and eggshell thickness. Adding high concentrations of TP may increase egg production. © 2021 Friends Science Publishers

scholarly journals Effects of Propolis on Selected Blood Indicators and Antioxidant Enzyme Activities in Broilers under Heat Stress

2009 ◽  
Vol 78 (1) ◽  
pp. 75-83 ◽  
Author(s):  
Pınar Tatlı Seven ◽  
Seval Yılmaz ◽  
Ismail Seven ◽  
Ibrahim H. Cercı ◽  
Mehmet A. Azman ◽  
...  
Keyword(s):  
Heat Stress ◽  
Vitamin C ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Basal Diet ◽  
Positive Control ◽  
Diet Group ◽  
Control Group ◽  
Antioxidant Enzyme Activities ◽  
Group I

In this study, we investigated the antioxidant activity of ethanol extracts of propolis (EEP) and vitamin C on biochemical indicators and antioxidant enzyme activities of broilers exposed to heat stress (at 34 °C). The experimental groups were as follows: group I (positive control) and group II (control) were fed a basal diet, group III (vitamin C) was fed a basal diet supplemented with 250 mg vitamin C as ascorbic acid/kg, group IV (EEP-0.5) was fed a basal diet supplemented with 0.5 g EEP/kg, group V (EEP-1) was fed a basal diet supplemented with 1 g EEP/kg, group VI (EEP-3) was fed a basal diet supplemented with 3 g EEP/kg. Plasma superoxide dismutase levels of positive control, control, vitamin C, EEP-0.5, EEP-1 and EEP-3 groups were found as 0.34, 1.23, 0.50, 0.90, 0.30 and 0.41 μkat/ml, respectively (p < 0.01). Aspartate transaminase (except for EEP-0.5 and EEP-1 groups) and alkaline phosphatase in the control group were significantly higher than those of positive control, vitamin-C and EEP-3 groups. Malondialdehyde level in plasma, liver and muscle tissues of control group were found significantly (p < 0.05) higher than those of positive control and EEP-3 groups. Catalase activities of blood, liver, kidney and heart were the highest in the control group. Reduced glutathione activities of plasma and liver of all groups were not significantly different from each other, whereas those of muscle, kidney and heart were significantly higher in the control group. Significantly lower levels of glutathione peroxidase were found in blood, liver and kidney tissues of the control group (p < 0.05), whereas those of muscle and heart were similar in all groups. The results of the present study suggest that EEP and specially EEP at the supplemented dose of 3 mg/kg diet might be considered to prevent oxidative stress in the broilers exposed to heat stress.

scholarly journals Dietary supplementation of Neem (Azadirachta indica) leaf extracts improved growth performance and reduced production cost in broilers

2020 ◽  
Vol 13 (6) ◽  
pp. 1050-1055
Author(s):  
Torun Kumar Paul ◽  
Md. Mehedi Hasan ◽  
Md. Anowarul Haque ◽  
Sudipta Talukder ◽  
Yousuf Ali Sarker ◽  
...  
Keyword(s):  
Body Weight ◽  
Azadirachta Indica ◽  
Basal Diet ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Broiler Chicks ◽  
Growth Promoter ◽  
Leaf Extracts ◽  
Neem Leaves

Background and Aim: Global trend to remove the antibiotic growth promoter (AGP) from animals contributes to the exploration of successful measures to sustain production and reduces the intestinal diseases in the post-AGP era. Plant extracts, therefore, have been used to improve performance and intestinal health. Here, we conducted a study to evaluate the effects of neem (Azadirachta indica) leaf extracts (NLE) as alternatives to AGPs in broiler chickens. Materials and Methods: Sixty day-old broiler chicks were assigned to 12-floor pens, each stocked with five birds and divided into three treatment groups of four pens per treatment. The groups were: Negative control, basal diet without additives; positive control, basal diet with antibiotics and vitamins; and NLE treated group, basal diet supplemented with 0.1% aqua extract of neem leaves. Results: Overall feed intake was significantly (p≤0.05) highest in the positive control. Higher body weight, higher dressing percentage, and lower feed conversion ratio were observed in birds treated with NLE compared to the negative control group (p≤0.05) but not the positive control group (p>0.05). There was no significant variation in hematology between different groups. Furthermore, the economic evaluation indicated that the NLE treatment was found cheaper than control and antibiotic treatment in cost-benefit analysis. Conclusion: We suggest NLE might be a cheaper alternative to antibiotics in broiler production as indicated by improved body weight and feed efficiency.

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