scholarly journals Penggunaan Antibiotik untuk Penanganan Ulkus dan Gangren Diabetikum Pasien Rawat Inap di Rumah Sakit

2020 ◽  
Vol 7 (2) ◽  
pp. 99
Author(s):  
Riyan Stiyanto ◽  
Iin Suhesti

Penyakit Diabetes melitus yang tidak dikelola dengan baik dapat menyebabkan komplikasi dan membahayakan kehidupan pengidapnya. Salah satu komplikasi diabetik yang sering terjadi adalah neuropati (kerusakan syaraf) di kaki yang menyebabkan ulkus kaki, infeksi, dan bahkan keharusan untuk amputasi kaki. Penelitian ini bertujuan untuk mengidentifikasi persentase penggunaan antibiotika empiris yang rasional serta pengaruhnya terhadap outcome terapi pada pasien Diabetes melitus dengan ulkus dan gangren di RSUD Dr Moewardi Surakarta dan RSUD Bagas Waras Klaten. Penelitian ini merupakan penelitian observasional dengan pengambilan data pada penelitian dilakukan secara retrospektif dan prospektif selama periode Januari sampai Agustus 2018. Ketidakrasionalan penggunaan antibiotika empiris dievaluasi dengan metode Gyssens. Sebanyak 36 pasien yang memenuhi kriteria inklusi 75% pasien mendapatkan terapi antibiotika empiris yang rasional dan 25% pasien mendapatkan terapi antibiotika empiris yang tidak rasional. Uji Chi Square dengan taraf kepercayaan 5% (p < 0,05) digunakan untuk membandingkan rasionalitas pengunaan antibiotika terhadap outcome terapi. Hasil Fisher’s Exact Test (Two Tailed) menunjukkan bahwa ada hubungan/pengaruh antara rasionalitas penggunaan antibiotika empiris dengan outcome terapi tetapi pemberian antibiotika empiris tidak berpengaruh pada angka leukosit bagi pasien, baik di RSUD Bagas Waras Klaten maupun RSUD dr. Moewardi Surakarta.Diabetes mellitus that is not managed properly can cause complications to endanger life. One of the diabetic complications that often occurs is foot neuropathy (nerve damage) inducing foot ulcers, infections, and even the necessity for a leg amputation. This study aims to determine the percentage of rational use of empirical antibiotics and their effects on outcomes therapy of diabetes mellitus patient with ulcers and gangrene in RSUD dr. Moewardi Hospital Surakarta and Bagas Waras Hospital Klaten. This study is an observational study with data collection in the study carried out retrospectively and prospectively from January to August 2018. The irrationality of using empirical antibiotics evaluated by the Gyssens method. Thirty six patients were enrolled and 75% of them treated with rational and empirical antibiotic therapy,. Chi-Square Test with a confidence level of 5% (p <0.05) used to compare the rationality of antibiotic use to the therapeutic outcome, the results of the Fisher Exact Test (Two-Tailed) indicated that there were relationship/influence between the rationality of using empirical antibiotics and outcomes therapy, but there was no influence between the rationality of using empirical antibiotics and leucocyte both in RSUD Bagas Waras Klaten and RSUD dr. Moewardi Surakarta.Keywords: Diabetes mellitus, therapeutic outcome, empirical antibiotic rationality

2019 ◽  
Vol 14 (3) ◽  
pp. 247-252
Author(s):  
Juripah Juripah ◽  
Muzakkir Muzakkir ◽  
Sri Darmawan

Orang dengan diabetes mellitus memiliki peningkatan mengembangkan sejumlah masalah kesehatan yang mengancam jiwa. Kadar glukosa darah yang tinggi dapat menyebabkan kerusakan pembuluh darah umum yang dapat mempengaruhi jantung, mata, ginjal, saraf, dan dapat mengakibatkan berbagai komplikasi. Sedangkan pola makan merupakan asupan makanan yang memberikan berbagai macam jumlah, jadwal dan jenis makanan yang didapatkan seseorang. Pengaturan pola makan yang tidak tepat dapat meningkatkan kadar glukosa dalam darah sehingga seseorang rentang terkena penyakit diabetes melitus. Penelitian ini bertujuan untuk mengetahui hubungan antara pola makan terhadap kejadian diabetes mellitus. Jenis penelitian yang digunakan adalah non experiment dengan metode survey analitik. Dengan menggunakan pendekatan cross sectional. Populasi dalam penelitian ini yaitu 47 responden. Sampel diambil menggunakan tehnik total sampling. Berdasarkan hasil penelitian menunjukkan bahwa dari total 47 responden terdapat 21 responden yang memiliki pola makan baik (44.7 %). Dimana Pola makan baik yang tidak menderita sebanyak 13 responden (27.7%), sedangkan pola makan baik yang  menderita sebanyak 8 responden (17.0%). Kemudian 26 responden yang memiliki pola makan kurang baik (55.3%). Dimana pola makan kurang baik yang tidak menderita sebanyak 8 responden (17.0%), sedangkan pola makan kurang baik yang  menderita sebanyak 18  responden (38.3%). Setelah dilakukan uji statistic dengan menggunakan uji chi-square test maka berdasarkan hasil fisher’s exact test didapatkan nilai p = 0,033 yang menunjukkan p<0,05, maka dengan demikian dapat disimpulkan bahwa Ha diterima dan H0 ditolak atau ada hubungan yang signifikan antara pola makan dengan kejadian diabetes mellitus di wilayah kerja puskesmas kassi-kassi kota Makassar.


2016 ◽  
Vol 4 (3) ◽  
pp. 365-371
Author(s):  
Sabita Subedi ◽  
Meera Prajapati ◽  
Bhojan Dhakal

A cross sectional study was conducted in Eastern and Western parts of Chitwan district from November 2015 to April, 2016  in two parts, the social study followed by biological to determine and compare the prevalence, distribution of antibodies, and level of awareness of farmers  against Brucella abortus in cattle of the two regions of same district. Altogether blood samples of 92 cattle were taken for detection of Brucella antibodies by using RBPT test and the positive samples were further retested by Indirect ELISA test through ID Vet iELISA kit 2016. The samples which showed positive on both tests were confirmed as seropositive. Chi -square test and Fisher Exact test was used to find out the association between various variables. The result showed that 14.13% (13/92) and 10.86% (10/92) sample were positive by RBPT and iELISA test respectively. There was no significant prevalence differences (p>0.05) on location, age group, breed type, and method of service (artificial and natural) used in cattle. Comparing abortion with prevalence of Brucellosis, there was significant differences (p<0.05) in the result of both RBPT and iELISA test. Inferring from this result, there is association between the abortion and occurrence of Brucellosis. The higher significant prevalence differences (p<0.01) was according to the time of abortion where higher seropositivity was obtained in the cattle aborted on 5-7th month of pregnancy and cattle of 3rd parity. The study showed the existence of Brucellosis in Chitwan district with no adoption of any preventive measures against this disease, so here is current need of the strategies for its prevention and control in order to mitigate such overwhelming situation.Int J Appl Sci Biotechnol, Vol 4(3): 365-371


2006 ◽  
Vol 43 (4) ◽  
pp. 435-441 ◽  
Author(s):  
Deborah A. Driscoll ◽  
Torrey Boland ◽  
Beverly S. Emanuel ◽  
Richard E. Kirschner ◽  
Don LaRossa ◽  
...  

Objective To evaluate potential modifiers of the palatal phenotype in individuals with the 22q11.2 deletion syndrome. Design Data from 356 subjects enrolled in a study of the 22q11.2 deletion syndrome were used to evaluate potential modifiers of the palatal phenotype. Specifically, subjects with and without velopharyngeal inadequacy and/or structural malformations of the palate were compared with respect to gender, race, and genotype for variants of seven genes that may influence palatal development. Methods The chi-square test or Fisher exact test was used to evaluate the association between palatal phenotype and each potential modifier. Odds ratios and their associated 95% confidence intervals were used to measure the magnitude of the association between palatal phenotype, subject gender and race, and each of the bi-allelic variants. Results The palatal phenotype observed in individuals with the 22q11.2 deletion syndrome was significantly associated with both gender and race. In addition, there was tentative evidence that the palatal phenotype may be influenced by variation within the gene that encodes methionine synthase. Conclusions Variation in the palatal phenotype observed between individuals with the 22q11.2 deletion syndrome may be related to personal characteristics such as gender and race as well as variation within genes that reside outside of the 22q11.2 region.


2019 ◽  
Vol 4 (1) ◽  
pp. 50
Author(s):  
I Wayan Suardana ◽  
I Wayan Mustika ◽  
Dewa Ayu Sri Utami

ABSTRAKTujuan: menganalisis hubungan perilaku pencegahan dengan kejadian komplikasi akut pada pasien Diabetes Melitus (DM). Metode: Jenis penelitian yang digunakan adalah penelitian correlational. Tehnik sampling yang digunakan adalah purposive sampling dengan jumlah sampel 85 orang. Instrumen yang digunakan dikembangkan dari instrumen The Diabetes Self-Management Questionnaire (DSMQ) untuk menilai perilaku pencegahan pada pasien DM dan instrumen untuk menilai pengetahuan, sikap, dan perilaku. Data dianalisis secara univariate dan bivariat (chi-square test). Hasil: Hasil penelitian ini menunjukkan bahwa ada hubungan perilaku pencegahan dengan kejadian komplikasi akut pada pasien DM. Pasien DM yang memiliki perilaku pencegahan yang cukup (60-79%) mempunyai 4,73 kali untuk mengalami komplikasi akut pada DM. Diskusi: Tindakan pengendalian DM untuk mencegah komplikasi sangat diperlukan, khususnya dengan menjaga tingkat gula darah sedekat mungkin dengan normal. Kesimpulan: Perilaku pencegahan yang baik dapat mencegah terjadinya komplikasi pada penderita DM Type II.Kata Kunci: Perilaku, pencegahan, komplikasi, Diabetes MelitusRelationship Between Preventive Behaviour with Acute Complications Occurrence in Diabetes Mellitus Patients ABSTRACTAim: to analyze the relationship between preventive behavior with the incidence of acute complications in DM patients. Method: The type of research used is correlational research. The sampling technique used was purposive sampling with 85 samples. The Instruments of this research are developed from The Diabetes Self-Management Questionnaire (DSMQ) to assess the preventive behaviour in DM patients and instrument to assess knowledge, attitude, and behaviour. Data analysis using univariate and bivariate (chi-square test) analysis. Results: The results of this study indicate that there is a correlation between preventive behavior and the incidence of acute complications in DM patients. DM patients who was categorized in moderate preventive behaviour (60-79%) have 4.73 times experience acute complication in DM. Discusion: preventive behavior to prevent complication is necessary, especially by maintaining the blood glucose as close as possible to normal level. Conclusion: Good preventative behavior could prevent complications in patients with Type II of DM.Keywords: behaviour, prevention, complication, diabetes mellitus


2020 ◽  
Vol 23 (1) ◽  
pp. 41-47
Author(s):  
Putu Inge Ruth Suantika ◽  
Yanti Hermayanti ◽  
Titis Kurniawan

The lack of interest from the public and health workers, such as nurses to carry out a pap test, is one of the triggers of cervical cancer cases. The purpose of this study was to identify the implementation of pap tests and barriers of nurses in Bandung, West Java. This study used a cross-sectional descriptive study design with a sample of 286 married nurses. Data collection was conducted during two months. The analysis was conducted by the Fisher exact test or chi-square test. The results showed that the level of education and religion had a significant relationship with the pap test behavior (p= 0,000; p= 0.031). The most perceived barrier was that respondents felt uncomfortable with the male examiners. So it was recommended to provide female examiners in the ob-gyn section in the hospitals and to improve the nurses' perceptions with pap test. Keywords: barrier, nurse, pap smear, practice Abstrak Perilaku dan hambatan pap smear pada perawat di Kota Bandung, Jawa Barat. Fenomena yang terjadi pada kasus kanker serviks adalah minimnya minat dari masyarakat bahkan petugas kesehatan seperti perawat untuk melakukan pap smear sebagai bentuk pencegahan kanker serviks. Tujuan penelitian ini adalah untuk mengidentifikasi pelaksanaan pap smear serta hambatannya pada perawat di Kota Bandung, Jawa Barat. Penelitian ini menggunakan desain studi deskriptif cross-sectional dengan jumlah sampel 286 perawat yang sudah menikah. Pengumpulan data dilakukan pada Februari hingga Maret 2018. Analisis menggunakan fisher exact test atau chi-square test. Hasil penelitian menunjukkan bahwa tingkat pendidikan dan agama memiliki hubungan yang signifikan dengan perilaku pap smear (p= 0.000; p= 0.0301). Hambatan yang paling dirasakan adalah responden merasa kurang nyaman dengan pemeriksa laki-laki sehingga direkomendasikan untuk penyediaan pemeriksa perempuan pada bagian obgyn di rumah sakit serta memperbaiki persepsi perawat yang salah terhadap pap smear.  Kata Kunci: hambatan, pap smear, perawat, perilaku


2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Mario E. Katuuk ◽  
Vandri D. Kallo

Abstract: Motivation of each individual is related to the self-efficacy that each individual has. The low level of client motivation affects client's self-efficacy, so that self-care management of DM patients cannot run well. The purpose of this study is to know the relationship between motivation and self-efficacy in patients with type 2 diabetes mellitus at the GMIM Hospital Pancaran Kasih Manado in 2018. The Design of this study was descriptive analytical with cross sectional approach. The study was conducted at the GMIM Hospital Pancaran Kasih Manado. The sample used was 34 patients. The instruments used were questionnaire demographic characteristics of respondents, motivational questionnaires, and self-efficacy questionnaires tested using the Fisher Exact test. The results of the Fisher Exact statistic test are the relationship between motivation and self-efficacy of patients with Type 2 Diabetes Mellitus at GMIM General Hospital Pancaran Kasih Manado obtained p = 0.026 (α = 0.05). The conclusion is that there is a relationship between motivation and self-efficacy of patients with Type 2 Diabetes Mellitus in RSU GMIM Pancaran Kasih Manado. Keywords: Motivation, Self-Efficacy.Abstrak: Motivasi dari setiap individu berkaitan dengan efikasi diri yang dimiliki oleh masing-masing individu tersebut. Tingkat motivasi klien yang rendah mempengaruhi efikasi diri klien, sehingga manajemen perawatan diri pasien DM tidak dapat berjalan dengan baik. Tujuan dalam penelitian ini ialah diketahui hubungan antara motivasi dengan efikasi diri pada pasien diabetes melitus tipe 2 di RSU GMIM Pancaran Kasih Manado tahun 2018.. Jenis penelitian yang digunakan adalah deskriptif analitik dengan pendekatan cross sectional. Penelitian dilaksanakan di RSU GMIM Pancaran Kasih Manado.. Sampel yang digunakan sebanyak 34 pasien. Instrumen yang digunakan kuesioner karakteristik demografi responden, kuesioner motivasi, dan kuesioner efikasi diri yang diuji menggunakan uji Fisher Exact. Hasil uji statistik Fisher Exact hubungan antara motivasi dengan efikasi diri pasien Diabetes Melitus Tipe 2 di Rumah Sakit Umum GMIM Pancaran Kasih Manado diperoleh nilai p = 0,026 (α = 0,05). Kesimpulan yaitu ada hubungan antara motivasi dengan efikasi diri pasien Diabetes Melitus Tipe 2 di RSU GMIM Pancaran Kasih Manado.Kata Kunci: Motivasi, Efikasi Diri


2017 ◽  
Vol 1 (01) ◽  
pp. 23
Author(s):  
Umi Faza ◽  
Dyah Umiyarni Purnamasari ◽  
Saryono Yono

Abstract  The aim of this study was to determine factors associated with diminished appetite in CKD patients undergoing hemodialysis therapy. This study is an observational analytic research with cross sectional design. Population of this study was CKD outpatients undergoing hemodialysis therapy in July- August 2016 in Prof. Dr. Margono Soekarjo Hospitals. Amount of 58 subjects taken by consecutive sampling. Appetite, sex, age, length of hemodialysis, frequency of nausea/vomiting, and depression were measured using questionnaire. Subjects who diminished appetite were 58,6%. More than half subjects were male (56,9%). Amount of 84,5% subjects were adults (19-59 years), 63,8% undergoing hemodialysis >1year, 39,7% experienced nausea/ vomiting and 53,4% were depression. Based on Chi-Square Test/ Fisher Exact Test, diminished appetite significantly associated with length of hemodialysis (p=0,041), frequency of nausea/vomiting (p=0,014), and depression (p=0,002). Dominant factors affected diminished appetite were depression and length of hemodialysis. Diminished appetite in CKD patients undergoing hemodialysis therapy associated with length of hemodialysis, frequency of nausea/vomit, and depression. Keyword : appetite, chronic kidney disease, hemodialysi  Abstrak Penelitian ini bertujuan untuk mengetahui faktor- faktor yang berhubungan dengan penurunan nafsu makan pada pasien Gagal Ginjal Kronik (GGK) yang menjalani terapi hemodialisis. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Populasi dari penelitian ini adalah pasien GGK rawat jalan yang menjalani terapi hemodialisis pada bulan Juli- Agustus 2016 di RSUD Prof. Dr. Margono Soekarjo Purwokerto. Sebanyak 58 subjek diambil dengan cara consecutive sampling. Nafsu makan, jenis kelamin, usia, lama hemodialisis, frekuensi mual/muntah, dan depresi diukur menggunakan kuesioner. Responden yang mengalami penurunan nafsu makan sebanyak 58,6%. Lebih dari separuh responden (56,9%) berjenis kelamin laki- laki dan 84,5% responden berusia dewasa (19-59 tahun). Sebanyak 63,8% responden menjalani hemodialisis >1tahun. Responden yang mengalami mual/muntah berat sebanyak 39,7% dan 53,4% mengalami depresi. Berdasarkan analisis bivariat menggunakan Uji Chi- Square/ Fisher Exact diperoleh hasil bahwa nafsu makan berhubungan secara signifikan dengan lama hemodialisis (p=0,041), frekuensi mual/ muntah (p=0,014), dan depresi (p=0,002). Faktor dominan yang mempengaruhi penurunan nafsu makan adalah depresi dan lama hemodialisis. Penurunan nafsu makan pada pasien GGK yang menjalani terapi hemodialisis berhubungan dengan lama hemodialisis, frekuensi mual/muntah, dan depresi. Kata kunci : gagal ginjal, hemodialisa, nafsu makan  


2019 ◽  
Vol 2 (1) ◽  
pp. 101-108
Author(s):  
Berthiana Berthiana ◽  
Mimin Lestari ◽  
Dian Ana Mutriqah

The world is now inhabited by 171 million people with Diabetes Mellitus (DM) and will double, an estimated 366 million by 2030. Obesity is a risk factor for type II DM. From the results of surveys and observations of researchers at the Palangka Raya Polytechnic, it was seen that some special program class students fall into the category of overweight and obese. This research aims to find out the relationship between overweight and the risk level of type II diabetes melitus in class students specialized in nursing and midwifery courses at Palangka Raya Polytechnic. A quantitative study with correlational studies and research design using a cross-sectional approach. There is a significant relationship between overweight to the risk level of type II DM based on the analysis of chi-square test data, obtained p-value = 0.077. There was a relationship between excess body weight based on body mass index on the risk level of type II DM


e-NERS ◽  
2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Martha Revy Sarame ◽  
A. Y. Ismanto ◽  
Abram Babakal

Abstract: Immunization is the vaccine into the body in the form of weakened germs that cause the body to produce antibodies but not cause disease, even children become immune.  The research objective was to determine the relationship of maternal knowledge about immunization with complete basic immunization in infants at IHC Health Center Village Paniki working area Ondong Tagulandang Biaro Siau Islands District . The study design was cross sectional method and using Chi-Square test on the value of the Fisher Exact Test. The study was conducted on 32 mothers of infants aged 9-12 months. Sampling with a total sampling instrument in the form of a questionnaire study to determine the motherʾs knowledge and KMS (Card Towards Health) to determine the completeness of immunization. The analysis shows there is a significant relationship between maternal knowledge about immunization with complete basic immunization in infants (p = 0,000). Conclusion that mothers with a good knowledge of immunization will do complete basic immunization in children compared to mothers with less knowledge about immunization. Keywords: Knowledge mother, Completed Basic Immunization.   Abstrak: Imunisasi  adalah pemberian vaksin ke dalam tubuh berupa bibit penykit  yang  dilemahkan yang menyebabkan tubuh memproduksi antibodi tetapi tidak menimbulkan penyakit, bahkan anak menjadi kebal. Tujuan penelitian adalah untuk mengetahui  hubungan pengetahuan ibu tentang imunisasi dengan kelengkapan pemberian imunisasi dasar pada bayi di Posyandu Kelurahan Paniki wilayah kerja Puskesmas Ondong Kabupaten Kepulauan Siau Tagulandang Biaro. Desain penelitian ini menggunakan metode Cross Sectional dan menggunakan  uji Chi-Square pada nilai Fisher Exact Test. Penelitian dilakukan pada 32 ibu yang memiliki bayi berusia 9-12 bulan. Pengambilan sampel secara total sampling dengan instrument penelitian berupa kuesioner untuk mengetahui pengetahuan ibu dan KMS (Kartu Menuju Sehat) untuk mengetahui kelengkapan imunisasi. Hasil analisis menunjukkan  terdapat hubungan bermakna antara pengetahuan ibu tentang imunisasi dengan kelengkapan pemberian imunisasi dasar pada bayi (p=0.000). Kesimpulan yaitu ibu dengan pengetahuan tentang imunisasi yang baik akan melakukan pemberian imunisasi dasar lengkap pada anaknya dibandingkan ibu dengan  pengetahuan tentang imunisasi yang kurang. Kata kunci: Pengetahuan ibu, Kelengkapan Imunisasi Dasar.


2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Siti Uswatun Chasanah ◽  
Anida Anida ◽  
Desi Susana

Background: Mellitus Diabetes is a chronic degenerative disease of increasing prevalence. Diabetes Mellitus  has characteristics such  as hyperglycemia that occurs due to abnormal insulin sekreksi. Insulin or both that cause a variety of chronic complications in the eyes of the kidneys, nerves, and blood vessels.Objective: to determine the relationship of the level of knowledge about the blood sugar levels in Diabetes Mellitus patient compliance to blood sugar control in the health center in Depok 3, Sleman, Yogyakarta.Method: Kind of research is observasional analytic with cross sectionalapproach. The study population was all patients with Diabetes Mellitus in thehealth center in Depok 3, Sleman, Yogyakarta, totaling 95 people. A sample size 48 people. Data collection was done bygiving kueaioner to all the respondents of the study. Processing data using Chi Square test with a standard error of 5% and α = 0,05.Result: Based onbiavariate analiysis there is no relationship between the level of knowledge about the blood sugar levels in Diabetes Mellitus patient compliance to blood sugar control in primary Depok 3, Sleman, Yogyakarta is (p = 0,119).Conclusion: There is no relationship between the level of knowledge about the blood sugar levels in Diabetes Mellitus patient compliance to blood sugar control in health center in Depok 3, Sleman. Yogyakarta.


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