scholarly journals EFFECTIVENESS OF VARIOUS CONCENTRATIONS OF LEMONGRASS LEAF EXTRACT LOTION (Cymbopogon nardus) AS REPELLENT OF AEDES AEGYPTI MOSQUITOES

2020 ◽  
Vol 39 (4) ◽  
pp. 164-170
Author(s):  
Firda - Ro'in
Keyword(s):  
Aedes Aegypti ◽  
Leaf Extract ◽  
Hemorrhagic Fever ◽  
Mosquito Vector ◽  
Protective Capacity ◽  
Group Design ◽  
Cymbopogon Nardus ◽  
Hand Control ◽  
Experimental Laboratory ◽  
Safe Control

Effectiveness Of Various Concentrations Of Lemongrass Leaf Extract Lotion (Cymbopogon nardus) As Repellent Of Aedes aegypti Mosquitoes. Dengue Hemorrhagic Fever (DHF) is a disease caused by dengue virus which is transmitted through the bite of the Aedes aegypti mosquito. Vector control efforts that are popular in the community are using chemical insecticides. The use of insecticides can cause mosquito resistance and cause poisoning in humans. Then effective controls need to be developed to avoid these impacts. Safe control of health and environmentally friendly is to use natural repellent derived from plants, one of which is lemongrass leaf (Cymbopogon nardus). The purpose of this study is to know the effectiveness of various concentrations of lemongrass leaf extract lotion (Cymbopogon nardus) as repellent of Aedes aegypti mosquitoes. This type of research is an experimental laboratory with the research design of The Posttest - Only Controlled Group Design. The research method by hand control and treatment is presented in a cage containing 25 Aedes aegypti mosquitoes for 6 hours with repetition 10 times each hour. The results showed that a concentration of 20% had an average protective capacity of 82.8%, a concentration of 40% had an average protective capacity of 95.0%, an concentration of 80% had an average protective capacity of 98.1% and lotion repellent from chemicals with the brand "X" has an average protection capacity of 88.6%. The results of the Kruskal Wallis analysis proved significant with p = 0.003 α (0.05), so there were significant differences in the protective power. The conclusion of the study was that the lemongrass leaf extract lotion was effectively used as a repellent of Aedes aegypti mosquitoes at a concentration of 40% and 80% because the protective power value 90% even though it had been used for 6 hours.

scholarly journals EFFECTIVENESS OF LOTION EXTRACT OF VARIOUS TYPE OF PLANTS AS Aedes aegypti MOSQUITO REPPELENT

2020 ◽  
Vol 39 (4) ◽  
pp. 203-209
Author(s):  
Agus - Subagiyo
Keyword(s):  
Aedes Aegypti ◽  
Leaf Extract ◽  
Statistical Tests ◽  
Hemorrhagic Fever ◽  
Negative Control ◽  
Toxic Substances ◽  
Research Needs ◽  
Protective Capacity ◽  
Leaf Extracts ◽  
The Difference

Effort to control DHF (Dengue Hemorrhagic Fever) vectors without toxic substances by using natural and enviromentally friendly materials was natural repellent made using plants that were widely available in the community.Many types of plants contain  various secondary metabolite compound substances that have the potential to be used as natural insecticides, especially as repellent of the Aedes Aegypti mosquito. The research needs  to be done to determine the effectiveness of basil leaves, citronella leaves, clove leaves and betel leaves as a repellent against Aedes Aegypti mosquitoes. This research method was an experiment in the laboratory. The materials used for this research were basil leaves, citronella leaves, clove leaves, and betel leaves. The extracted leaves were then made lotions with certain formulas, tested as a natural repellent against Aedes Aegypti mosquitoes. The concentrations used were 20%, 40% and 80% as well as negative control (0%) and positive control (brand x lotions). The number of mosquitoes used in the study were 25 x 4 treatments = 100 mosquitoes. The replication or repetition was done 10 times. To find out the difference in the number of Aedes Aegypti mosquitoes that perch on the hands of probandus which has been smeared with basil leaf, citronella leaf, clove leaf and betel leaf extracts uses Anova Statistical tests and kruskal wallis. To see the difference between concentrations was tested with LSD or Mann-Whitney test. The calculation result of the number of Aedes Aegypti mosquitoes that perch before and after applying the lotion, the lowest was the lotion of citronella leaf extract 0% (11); 20% (2); 40% (1); 80% (1); The highest protection capacity of extract lotion is citronella leaves with concetrations of 20% (81,1%); 40% (95%), 80%(98,2%); There were no significant differences between the lotion concentrations of 20% and 80%, while the concentration of 40% is significantly different. Then the LSD follow-up test finds that the protective capacity of lotion of clove leaf extract is negative and citronella leaf extract is positive. The most effective protection capacity against Aedes Aegypti mosquitoes was lotion of citronella leaf extract with concentration of 40% (95%) and a concentration of 80% (98,2%), proven by the value of protection capacity that is stable even though it has been used for up to 6 hours and can exceed the protection capacity of lotion x (90,3%). It is reccomended that further research needs to be developed to optimize the lotion of citronella leaf extract 40% and 80% with orgonolaptic test of color, aroma, stickness and comfort of its use.

scholarly journals Comparing Effectiveness of Hay Infusion and Sugar Fermentation Solution as Ovitrap's Attractans to Aedes aegypti

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Nastiti Widoretno
Keyword(s):  
Aedes Aegypti ◽  
Gravid Female ◽  
Hemorrhagic Fever ◽  
Mosquito Vector ◽  
Sugar Fermentation ◽  
Randomized Design ◽  
Experimental Laboratory ◽  
The Difference ◽  
Gravid Mosquitoes ◽  
Fermentation Solution

Dengue Hemorrhagic Fever (DHF) is still one of the major public health problems in the world and Indonesia. There are several methods of mosquito vector control, one of them is the use of ovitrap and the addition of attractants which is a compound that may attract gravid mosquitoes to lay eggs. Some examples of attractants are hay infusion and sugar fermentation solution. This research aimed to compare effectiveness of hay infusion  and sugar fermentation solution as Aedes aegypti attractants. This research type was true experimental laboratory with complete randomized design which is divided into 3 groups of ovitrap containing aquades as control, 20% hay infusion and 20% sugar fermentation solution. Ovitraps with those attractants were put into a mosquito coop containing 25 gravid female mosquitoes. Mosquito’s eggs counting was done after 2 days with 9 times repetition. The data were then analyzed using Kruskal-Wallis and Mann-Whitney test. It was found that the difference of mosquito’s eggs number in the ovitrap containing the fermentation solution of sugar and hay infusion had a significance value of 0.000 (p> 0,05). It means that hay infusion is more effective compared with sugar fermentation. Keywords                   : DHF, ovitrap, attractant, hay infusion, sugar fermentation solution

scholarly journals Pengaruh Konsentrasi dan Time Efek Ekstrak Batang Serai Wangi (Cymbopogon nardus) dalam Bentuk Spray sebagai Bioinsektisida Nyamuk Aedes aegypti

2019 ◽  
Vol 2 (1) ◽  
pp. 12
Author(s):  
Khoirul Anam ◽  
Isa Ma’rufi ◽  
Dwi Wahyuni
Keyword(s):  
Aedes Aegypti ◽  
Hemorrhagic Fever ◽  
Research Unit ◽  
Probit Analysis ◽  
Time Effect ◽  
Repeated Measure ◽  
Mosquito Vector ◽  
Control Effort ◽  
Cymbopogon Nardus ◽  
Pure Research

Dengue Hemorrhagic Fever is an insect tropic disease that always threatens the Indonesian population every year and becomes an outbreak in several regencies/cities in Indonesia after the changing seasons. The Aedes aegypti mosquito vector control effort has been carried out both physically with the PSN program or chemically using synthetic insecticides that can be directed against both adult mosquitoes and larvae. Fragrant citronella extract based on previous research contains many alkaloid compounds that can inhibit cholinesterase enzymes such as synthetic organophosphate class insecticides. The purpose of this study was to analyze the effect of concentration and time effect of citronella extract (Cymbopogon nardus) in the form of a spray as a natural bioinsecticide to control the Aedes aegypti mosquito. This research belongs to a pure research design (true experiment) with factorial design. The research unit has 3 units plus 1 unit as a control using 25 mosquitoes for each research unit. Data analysis in this study used the Repeated Measure GLM and Probit analysis. The results showed that the concentration and time effect of citronella extract had a test result of 0.0001 <0.005. The conclusion of the study was the effect of concentration and time effect of citronella extract on the death of Aedes aegypti mosquitoes. The results of the probit analysis found that the value of LT50 was 27.49 minutes after the intervention and LC50 was 3,198 ppm. Keywords: Frarant of citronella , spray, Aedes aegypti

scholarly journals Efektivitas Ekstrak Daun Sirih (Piper betle L) dan Ekstrak Bawang Putih (Allium sativum) terhadap Mortalitas Larva Nyamuk Aedes aegypti

bionature ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Amirullah Amirullah ◽  
Nurhayu Malik ◽  
Rosmaya Rosmaya
Keyword(s):  
Aedes Aegypti ◽  
Endemic Area ◽  
Leaf Extract ◽  
Allium Sativum ◽  
Larval Mortality ◽  
Hemorrhagic Fever ◽  
Garlic Extract ◽  
Piper Betle ◽  
Mosquito Larvae ◽  
Betel Leaf

Abstract. The study of the efficacy of betel leaf extract (Piper betle L.) and garlic extract (Allium sativum) on the mortality of Aedes aegypti mosquito larvae was carried out at the Zoology Laboratory of the Faculty of Mathematics and Natural Sciences, Halu Oleo Kendari University. Aedes aegypti mosquito larvae were obtained from the rearing of F2 from Aedes aegypti eggs that were taken by ovitrap from in Kambu Village, Kendari City, which is an endemic area of Dengue Hemorrhagic Fever (DHF). Extrac of betel leaf (Piper betle L.) and garlic extract (Allium sativum) at concentrations of 1.0%, 2.0% and 3.0% respectively and their combinations were given to Aedes aegypti larvae (L4). The results showed that the highest larval mortality (88%) occurred after 24 hours of exposure to betel leaf extract (Piper betle L.) at a concentration of 3%, whereas with garlic extract (Allium sativum) the highest larval mortality (98%) occurred at concentration 3 %, and for the highest larval mortality (99%) found in a combination of 3% betel leaf extract (Piper betle L.) and 3% garlic extract (Allium sativum). Based on WHO (2009), the most effective treatment for killing Aedes aegyti larvae is 3% garlic (Allium sativum) extract and a combination of 3% betel leaf extract (Piper betle L.) and 3% garlic extract (Allium sativum).Keywords:  Biopesticide, Mortality, Aedes aegypti, betle leaf (Piper betle L.), garlic (Allium sativum).

scholarly journals Uji daya hambat ekstrak daun stevia (Stevia rebaudiana Bertoni M.) terhadap pertumbuhan Staphylococcus aureus secara in vitro

e-GIGI ◽  
2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Yaromis Wenda ◽  
Pemsi M. Wowor ◽  
Michael A. Leman
Keyword(s):  
Staphylococcus Aureus ◽  
Leaf Extract ◽  
Stevia Rebaudiana ◽  
Inhibition Zone ◽  
Group Design ◽  
Stevia Rebaudiana Bertoni ◽  
Post Test ◽  
Experimental Laboratory ◽  
Active Substances

Abstract: Currently, oral health requires comprehensive handling by dentists and other health professionals. Osteomyelitis is an infection that occurs in bone tissue and bone marrow of the jaw and/or cortical bones, predominantly caused by Staphylococcus aureus. Medicinal plants in Indonesia have been widely used as traditional medicine inter alia stevia (Stevia rebaudiana Bertoni M.). This stevia plant has components that are typical natural sweetener and stevioside which has the characteristics as antibacterial, antiviral, anti-inflammatory, antimicrobial, and antifungal, and other active substances including tannins, alkaloids, flavonoids, and phenol. This was an experimental laboratory study with the post test only group design. Subjects were Staphylococcus aureus bacteria. The results showed that stevia leaf extract had inhibition zone to Staphylococcus aureus growth of 10.32 mm which was categorized as strong according to Davis and Stout 1971. Conclusion: Stevia leaf extract (Stevia rebaudiana Berrtoni M.) had strong inhibition to Staphylococcus aureus.Keywords: osteomyelitis, stevia (Stevia rebaudiana Bertoni M.), Staphylococcus aureusAbstrak: Dewasa ini kesehatan gigi dan mulut memerlukan penanganan secara komperhensif oleh dokter gigi maupun tenaga kesehatan lainnya. Salah satu penyakit yang sering dijumpai yaitu osteomielitis pada jaringan tulang dan sum-sum tulang rahang dan/atau korteks tulang dengan penyebab utama ialah bakteri Staphylococcus aureus. Tanaman herbal di Indonesia telah banyak digunakan sebagai obat tradisional; salah satunya ialah tanaman stevia (Stevia rebaudiana Bertoni M.). Tanaman stevia memiliki komponen yang bersifat pemanis alami, stevioside yang berefek antibakteri, antivirus, antiinflamasi, antifungsi, dan antimikroba, serta zat aktif di antaranya ialah tannin, alkaloid, flavonoid, dan fenol. Jenis penelitian ini ialah eksperimental laboratorik dengan post test only group design. Subyek penelitian ialah bakteri Staphylococcus aureus. Hasil penelitian memperlihatkan bahwa ekstrak daun stevia (Stevia rebaudiana Bertoni M.) mempunyai rerata zona hambat terhadap pertumbuhan bakteri Staphylococcus aureus sebesar 10,32 mm yang tergolong kuat menurut Davis dan Stout 1971. Simpulan: Ekstrak daun stevia (Stevia rebaudiana Berrtoni M.) memiliki daya hambat yang kuat terhadap bakteri Staphylococcus aureus.Kata kunci: osteomielitis, stevia (Stevia rebaudiana Bertoni M.), Staphylococcus aureus

scholarly journals Gambaran indeks Maya pada rumah penderita demam berdarah dengue di Kelurahan Kombos Barat Kecamatan Singkil tahun 2015

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Ivan T. Sigarlaki ◽  
Victor D. Pijoh ◽  
Josef S.B. Tuda
Keyword(s):  
Aedes Aegypti ◽  
Aedes Albopictus ◽  
Dengue Hemorrhagic Fever ◽  
Risk Index ◽  
Public Health Problem ◽  
Hemorrhagic Fever ◽  
Viral Disease ◽  
Environmental Data ◽  
Mosquito Vector ◽  
Short Time

Abstract: Dengue hemorrhagic fever (DHF) is a viral disease that can cause death within a very short time (a few days). The main vector of DHF is Aedes aegypti mosquito, whereas the potential vector is Aedes albopictus. In the context of prevention of DHF, environmental data associated with bionomics mosquito vector of DHF, the Maya Index, are needed. DHF is still a public health problem. And for the case that there is in the city of Manado in 2013, in this case in the district of Singkil, acquired as many as 43 cases of dengue hemorrhagic fever. This study aimed to describe the Maya Index at the houses of dengue hemorrhagic fever patients in the village of West Kombos, Singkil districts. Maya Index is based on hygiene risk index (HRI) and breeding risk index (BRI). This was a descriptive study. Samples were houses of patients with DHF in 2015 from January to December. The results showed that there were four patients during the year 2015. Observation of the four houses and calculation of the data indicated that two houses were in low category of Maya Index, one house in medium category of Maya Index, and one house in high category of Maya Index. Keywords: dengue hemorrhagic fever, Maya index Abstrak: Demam berdarah dengue (DBD) adalah penyakit virus yang berbahaya karena dapat menyebabkan kematian dalam waktu yang sangat singkat (beberapa hari). Vektor utama DBD ialah nyamuk Aedes aegypti, sedangkan vektor potensialnya ialah Aedes albopictus. Dalam konteks penanggulangan DBD, juga diperlukan data lingkungan terkait dengan segi bionomik nyamuk vektor DBD, yaitu Indeks Maya. DBD masih merupakan masalah kesehatan masyarakat di kota Manado. Pada tahun 2013, di Kecamatan Singkil didapatkan sebanyak 43 kasus DBD. Penelitian ini bertujuan untuk mengetahui gambaran Indeks Maya pada rumah penderita DBD di Kelurahan Kombos Barat Kecamatan Singkil. Indeks Maya didasarkan pada hygiene risk index (HRI) dan breeding risk index (BRI). Jenis penelitian ialah deskriptif. Sampel penelitian ialah rumah dari penderita DBD tahun 2015 sejak bulan Januari-Desember. Dari hasil penelitian didapatkan empat penderita sepanjang tahun 2015 dan setelah dilakukan observasi ke rumah penderita dan perhitungan data didapatkan dua rumah masuk pada kategori Indeks Maya rendah, satu rumah masuk pada kategori Indeks Maya sedang, dan satu rumah masuk kategori Indeks Maya tinggi.Kata kunci: demam berdarah dengue, indeks Maya

scholarly journals AKTIVITAS EKSTRAK RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb.) SEBAGAI LARVASIDA TERHADAP Aedes aegypti DI KECAMATAN KELAPA LIMA KOTA KUPANG

2020 ◽  
Vol 8 (1) ◽  
pp. 54-68
Author(s):  
Deswandi W. S. Berri ◽  
Julianty Almet ◽  
Diana Agustiani Wuri
Keyword(s):  
Aedes Aegypti ◽  
Vector Control ◽  
Research Method ◽  
Hemorrhagic Fever ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Mosquito Vector ◽  
Curcuma Xanthorrhiza ◽  
Mosquito Vector Control

Dengue hemorrhagic fever (DHF) is a disease that is found in some tropical and subtropical regions. This disease is caused by dengue virus and is transmitted to humans through the bite of the Aedes aegypti mosquito. the solution taken in controlling DHF is to break the life cycle of the Aedes aegypti mosquito. Vector control is generally carried out using synthetic larvicides, namely abate / temefos, but the use of abate can cause residues, environmental pollution, poisoning and resistance of the eradicated vectors so that natural larvasides from plants are needed namely temulawak rhizome (Curcuma xanthorrhiza Roxb.) for vector control. The purpose of this study was to determine whether temulawak rhizome extract was effective or not in killing Aedes aegypti larvae. This research method includes larva collection, identification and maintenance of mosquitoes, determining sample size, making extracts and testing effectiveness. This study used a control and experiment group with 3 repetitions in the minutes to 15, 30, 45, 60 and 1440 (24 Hours). The control group was positive control using abate and negative control using aquades while the eksperiment group used extract of temulawak rhizome (Curcuma xanthorrhiza Roxb.) with concentrations of 0.6%, 0.8%, 1%, 1.2% and 1.5%. The results of this study indicate that the temulawak rhizome extract (Curcuma xanthorrhiza Roxb.) effective as larvicides because at the lowest concentration 0.6% can kill 100% Aedes aegypti larvae.

scholarly journals The Effectiveness of Citrus Hystrix As Rapelant against Aedes Aegypti

2019 ◽  
Author(s):  
Anita Rosanty ◽  
Reni Yunus ◽  
Dian Yuniar SR
Keyword(s):  
Experimental Study ◽  
Aedes Aegypti ◽  
Dengue Virus ◽  
Leaf Extract ◽  
Hemorrhagic Fever ◽  
Life Cycles ◽  
Case Study Design ◽  
Aedes Mosquitoes ◽  
Vector Mosquito

Indonesia is the country with the highest cases of dengue fever in Southeast Asia. The WHO estimates a 50–100 million dengue infections worldwide every year. Dengue Hemorrhagic Fever (DHF) is transmitted through the bite of female Aedes mosquitoes infected with the Dengue virus. Mosquitoes Aedes aegypti is the main vector of the dengue virus. At the time, there is no cure for dengue so that the control efforts are focused on breaking the chain of life cycles. One effort to prevent the transmission of the dengue virus is to avoid vector mosquito bites. Repellent can reduce exposure to the bite of mosquitoes infected with the dengue virus. The aim of this study was to determine the effectiveness of the extract of citrus hystrix leaf as a repellent against the Aedes aegypti mosquitoes. This research is a laboratory experimental study with a one-shot case study design. In this study, the extract of citrus hystrix solution was made at a concentration of 10%, 20%, and 30%, and then the extract solution was used as a stock to make a 100-gram base lotion that would be used as a repellent. Repellent effectiveness is seen from the percentage of repellent protection power. The percentage of repellant protection used with the basic ingredients of Citrus hystrix leaf extract at concentrations of 10%, 20%, and 30%, respectively, at 93.33% 94.67%, and 97.33%. The extract of citrus hystrix leaf was found to be effective as a repellent against Aedes aegypti mosquitoes.

scholarly journals EFEKTIVITAS ABATE DAN EKSTRAK DAUN SIRIH (Piper betle) DALAM MEMATIKAN LARVA Aedes Aegypti L INSTAR III

Masker Medika ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 226-232
Author(s):  
Triana Oktaviani ◽  
Zairinayati Zairinayati
Keyword(s):  
Aedes Aegypti ◽  
Leaf Extract ◽  
Hemorrhagic Fever ◽  
Piper Betle ◽  
Mosquito Larvae ◽  
Betel Leaf ◽  
Preventive Effort ◽  
Randomized Design ◽  
Natural Insecticides ◽  
Completely Randomized Design

Latar Belakang: Aedes aegypti merupakan nyamuk yang dapat berperan sebagai vektor Demam Berdarah Dengue (DBD). Upaya promotif dan preventif menjadi mutlak dilakukan untuk memutus mata rantai penularan dengan membunuh larva nyamuk dengan larvasida alami menggunakan ekstrak daun sirih (Piper betle) sebagai insektisida alami. Tujuan dari penelitian: ini adalah untuk mengetahui perbedaan abate dan ekstrak daun sirih (Piper betle) dalam mematikan larva Aedes aegypti L instar III. Desain penelitian: ini bersifat eksperimen dengan menggunakan rancangan acak lengkap (RAL) yang terdiri dari 3 perlakuan 1 kontrol dan 8 kali pengulangan percobaan. Hasil Penelitian: dapat diketahui bahwa untuk penggunaan ekstrak daun sirih (Piper betle) dengan konsentrasi 5% dapat mematikan larva sebanyak 8 ekor, sedangkan konsentrasi 10% tidak dapat mematikan larva (0 larva) dan konsentrasi 15% dapat mematikan larva sebanyak 17 (85%) sedangkan untuk penggunaan abate dengan konsentrasi 5%, 10% dan 15% dapat mematikan larva sebanyak 160 larva (100%). Kesimpulan: bahwa abate mempunyai efektifitas lebih tinggi di banding dengan ekstrak daun sirh (Piper betle).     Background: Aedes aegypti is a mosquito that can act as a vector of dengue Hemorrhagic Fever (DHF). Promotove and preventive effort are absolutely necessary to break the chain to transmission by killing mosquito larvae with natural larvacides using betel leaf extract (Piper betle) as a natural insecticides. The purposes of this study: this was to determine the differences in abate and betel leaf extract (Piper batle) in kliing Aedes aegypti instar III larvae. Research methods this is an experimental study using a completely randomized design (CRD) consisting of 3 treatments 1 control and 8 repetitions of the experiment. The results: it can be seen that for the use of betel leaf extract(Piper betle) with a concentration cannot kill larvae in 17 (85%) whilke for the use of abate with a concentration of 5%, 10% and 15% can kill larvae of 160 (100%). Conclusion: that the abate has a higher effectiveness compared to sirih leaf extract.

scholarly journals THE EFFECTIVENESS TEST OF BETEL LEAF EXTRACT TOWARD THE DEVELOPMENT OF AEDES AEGYPTI SP LARVAE

Biospecies ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 1-7
Author(s):  
Firza Khairullah Sembiring ◽  
Riyani Susan BT Hasan
Keyword(s):  
Aedes Aegypti ◽  
Experimental Method ◽  
Leaf Extract ◽  
Sampling Method ◽  
Total Mortality ◽  
Hemorrhagic Fever ◽  
Betel Leaf ◽  
Significant Difference ◽  
Post Test ◽  
Confidence Index

This research was conducted to determine the effectiveness of betel leaf extract conducted at a concentration of 2.5%, 5.0%, 7.5%, 10% as larvicide toward the development of Aedes Aegypti Sp. Aedes Aegypti Sp larvae are dangerous vectors in Dengue Hemorrhagic Fever (DHF) in humans. The method in this research was carried out on an experimental method by using a post-test only design and sampling with a purposive sampling method. The effectiveness of betel leaf extract larvicide on the development of Aedes Aegypti Sp larvae was carried out by mixing betel leaf extract with several concentrations in one container Aedes Aegypti Sp larvae inside. The results obtained in this research were carried out by the Kruskal-Wallis test, the test found that there was a significant difference because it was given a 95% confidence index. The larvae treated with betel leaf extract with a concentration of 10% had the highest effectiveness in stopping the development of Aedes Aegypti Sp larvae, which proved at the mortality at a concentration of 10%, found total mortality of 20 larvae in 8 hours of treatment. Betel leaf extract with a concentration of 10% had the highest effectiveness of discontinuing the development of Aedes Aegypti Sp larvae.

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