scholarly journals Human Milk Microbiota and Oligosaccharides: A Glimpse into Benefits, Diversity and Correlations

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1123
Author(s):  
Carole Ayoub Moubareck
Keyword(s):  
Human Milk ◽  
Maternal Diet ◽  
Geographical Location ◽  
Intestinal Barrier ◽  
Bioactive Components ◽  
Bioactive Constituents ◽  
Ongoing Research ◽  
Genetic Significance ◽  
The Rich ◽  
Insight Into

Human milk represents a cornerstone for growth and development of infants, with extensive array of benefits. In addition to exceptionally nutritive and bioactive components, human milk encompasses a complex community of signature bacteria that helps establish infant gut microbiota, contributes to maturation of infant immune system, and competitively interferes with pathogens. Among bioactive constituents of milk, human milk oligosaccharides (HMOs) are particularly significant. These are non-digestible carbohydrates forming the third largest solid component in human milk. Valuable effects of HMOs include shaping intestinal microbiota, imparting antimicrobial effects, developing intestinal barrier, and modulating immune response. Moreover, recent investigations suggest correlations between HMOs and milk microbiota, with complex links possibly existing with environmental factors, genetics, geographical location, and other factors. In this review, and from a physiological and health implications perspective, milk benefits for newborns and mothers are highlighted. From a microbiological perspective, a focused insight into milk microbiota, including origins, diversity, benefits, and effect of maternal diet is presented. From a metabolic perspective, biochemical, physiological, and genetic significance of HMOs, and their probable relations to milk microbiota, are addressed. Ongoing research into mechanistic processes through which the rich biological assets of milk promote development, shaping of microbiota, and immunity is tackled.

scholarly journals Potential Health Benefits of Plant Food-Derived Bioactive Components: An Overview

Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 839
Author(s):  
Mrinal Samtiya ◽  
Rotimi E. Aluko ◽  
Tejpal Dhewa ◽  
José Manuel Moreno-Rojas
Keyword(s):  
Bioactive Compounds ◽  
Nutritive Value ◽  
Intestinal Barrier ◽  
Biologically Active ◽  
Bioactive Components ◽  
Bioactive Constituents ◽  
Potential Health ◽  
Plant Foods ◽  
Health Promoting ◽  
Bioactive Ingredients

Plant foods are consumed worldwide due to their immense energy density and nutritive value. Their consumption has been following an increasing trend due to several metabolic disorders linked to non-vegetarian diets. In addition to their nutritive value, plant foods contain several bioactive constituents that have been shown to possess health-promoting properties. Plant-derived bioactive compounds, such as biologically active proteins, polyphenols, phytosterols, biogenic amines, carotenoids, etc., have been reported to be beneficial for human health, for instance in cases of cancer, cardiovascular diseases, and diabetes, as well as for people with gut, immune function, and neurodegenerative disorders. Previous studies have reported that bioactive components possess antioxidative, anti-inflammatory, and immunomodulatory properties, in addition to improving intestinal barrier functioning etc., which contribute to their ability to mitigate the pathological impact of various human diseases. This review describes the bioactive components derived from fruit, vegetables, cereals, and other plant sources with health promoting attributes, and the mechanisms responsible for the bioactive properties of some of these plant components. This review mainly compiles the potential of food derived bioactive compounds, providing information for researchers that may be valuable for devising future strategies such as choosing promising bioactive ingredients to make functional foods for various non-communicable disorders.

Imereti Region's Natural - Recreational and Historical - Cultural Potential as Tourism Development Factor in Georgia

2019 ◽  
Vol 5 (2) ◽  
pp. 61
Author(s):  
Mikautadze Rusudan
Keyword(s):  
Geographical Location ◽  
Small Towns ◽  
Local Economy ◽  
Western Society ◽  
The Black Sea ◽  
Development Factor ◽  
Fast Pace ◽  
The Rich ◽  
Tourism Potential ◽  
Work Done

Imereti – is one of the smallest region on the Black Sea coast in Georgia. The geographical location, historical-cultural and natural monuments, the rich Imeretian hospitality traditions are a good prerequisite for the development of recreation and tourism. Imereti region is a growing tourist segment. For more than 900 historical and more than 350 natural monuments continuously presents the rich history of the country from the primitive societies until nowadays. Myths and legends related to Imereti ( Colchis kingdom, myth about Amirani (Prometheus), Golden Fleece, King Aetees and Medea and etc.) are well-known for the Western society. The work done for the popularization of these tourist products has greatly contributed to the growth of both organized and unorganized tourism. (80,000 men in 2007, in 2017 - more than 450,000). Today, tourism in Georgia is developing at a fast pace. Natural and historic monuments are the "Golden Keys" of the tourism potential of the region. We believe that tourism is a stimulus for the development of the local economy, and it should facilitate for staying of youth in the small towns by creating different jobs in order not to leave their country and therefore alienate from their national identities and culture.Key words: natural monuments; historical-cultural heritage; national identity; recreational resources.

scholarly journals The Triad Mother-Breast Milk-Infant as Predictor of Future Health: A Narrative Review

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 486 ◽  
Author(s):  
Elvira Verduci ◽  
Maria Lorella Giannì ◽  
Giulia Vizzari ◽  
Sara Vizzuso ◽  
Jacopo Cerasani ◽  
...  
Keyword(s):  
Health Outcome ◽  
Breast Milk ◽  
Human Milk ◽  
Maternal Diet ◽  
Milk Composition ◽  
Narrative Review ◽  
Future Health ◽  
Interconnected System ◽  
Offspring Health ◽  
Diet And Lifestyle

The benefits of human milk for both mother and infant are widely acknowledged. Human milk could represent a link between maternal and offspring health. The triad mother-breast milk-infant is an interconnected system in which maternal diet and lifestyle might have effects on infant’s health outcome. This link could be in part explained by epigenetics, even if the underlining mechanisms have not been fully clarified yet. The aim of this paper is to update the association between maternal diet and human milk, pointing out how maternal diet and lifestyle could be associated with breast-milk composition, hence with offspring’s health outcome.

scholarly journals Branched-chain fatty acid composition of human milk and the impact of maternal diet: the Global Exploration of Human Milk (GEHM) Study

2016 ◽  
Vol 105 (1) ◽  
pp. 177-184 ◽  
Author(s):  
Kelly A Dingess ◽  
Christina J Valentine ◽  
Nicholas J Ollberding ◽  
Barbara S Davidson ◽  
Jessica G Woo ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Human Milk ◽  
Acid Composition ◽  
Maternal Diet ◽  
Chain Fatty Acid ◽  
Branched Chain ◽  
The Impact

scholarly journals A breakdown in communication? Understanding the effects of aging on the human small intestine epithelium

2015 ◽  
Vol 129 (7) ◽  
pp. 529-531 ◽  
Author(s):  
Neil A. Mabbott
Keyword(s):  
Small Intestine ◽  
Barrier Function ◽  
Intestinal Barrier ◽  
Intestinal Barrier Function ◽  
Human Small Intestine ◽  
Small Intestinal ◽  
Effects Of Aging ◽  
Insight Into

A new study by Man and colleagues provides further insight into the effects of aging on small intestinal barrier function in humans. Here, their findings are briefly summarised and the wider implications discussed.

scholarly journals Mechanistic Insight into Antimicrobial and Antioxidant Potential of Jasminum Species: A Herbal Approach for Disease Management

Plants ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1089
Author(s):  
Acharya Balkrishna ◽  
Akansha Rohela ◽  
Abhishek Kumar ◽  
Ashwani Kumar ◽  
Vedpriya Arya ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Drug Resistance ◽  
Free Radicals ◽  
Free Radical ◽  
Microbial Pathogens ◽  
Free Radical Scavengers ◽  
Bioactive Constituents ◽  
Global Issues ◽  
Iridoid Glucosides ◽  
Insight Into

Drug resistance among microbial pathogens and oxidative stress caused by reactive oxygen species are two of the most challenging global issues. Firstly, drug-resistant pathogens cause several fatalities every year. Secondly aging and a variety of diseases, such as cardiovascular disease and cancer, are associated with free radical generated oxidative stress. The treatments currently available are limited, ineffective, or less efficient, so there is an immediate need to tackle these issues by looking for new therapies to resolve resistance and neutralize the harmful effects of free radicals. In the 21st century, the best way to save humans from them could be by using plants as well as their bioactive constituents. In this specific context, Jasminum is a major plant genus that is used in the Ayurvedic system of medicine to treat a variety of ailments. The information in this review was gathered from a variety of sources, including books, websites, and databases such as Science Direct, PubMed, and Google Scholar. In this review, a total of 14 species of Jasminum have been found to be efficient and effective against a wide variety of microbial pathogens. In addition, 14 species were found to be active free radical scavengers. The review is also focused on the disorders related to oxidative stress, and it was concluded that Jasminum grandiflorum and J. sambac normalized various parameters that were elevated by free radical generation. Alkaloids, flavonoids (rutoside), terpenes, phenols, and iridoid glucosides are among the main phytoconstituents found in various Jasminum species. Furthermore, this review also provides insight into the mechanistic basis of drug resistance, the generation of free radicals, and the role of Jasminum plants in combating resistance and neutralizing free radicals.

Profaning the Sacred: The Unorthodox Financial Activities of Catholic Clerics During the Napoleonic Period, 1796–1814

2021 ◽  
Vol 51 (4) ◽  
pp. 523-542
Author(s):  
Christopher Korten
Keyword(s):  
Precious Metals ◽  
Religious Communities ◽  
Critical Periods ◽  
For Profit ◽  
Sacred And Profane ◽  
The Rich ◽  
The Times ◽  
First Time ◽  
Insight Into

This article reveals for the first time how Catholic clerics survived financially during the Napoleonic period in Italy (1796–1814). Despite the very rich, 200-year historiography on one of the Church's most critical periods, there is almost nothing on how religious clerics coped at this time. Their institutions had been despoiled by the French, often in collaboration with locals, negating traditional forms of clerical income, such as alms or rental income from non-ecclesiastical properties. This caused clerics to search out unorthodox – at times, non-canonical – ways of eking out a living, either for themselves, their religious communities or both, as such distinctions were often blurred. Masses were monetized and traded; ecclesiastical paraphernalia composed of precious metals were smelted and commodified, and relics were sold for profit. The uncovering of these controversial acts by men who in normal times were upstanding reveals the desperation of the times and provides insight into the rich discussion on determining the degrees of separation (and overlap) between the sacred and profane.

scholarly journals De wereld als sciencefictionroman. Over De goede zoon van Rob van Essen

2021 ◽  
Vol 59 (3) ◽  
pp. 227-242
Author(s):  
Erica van Boven
Keyword(s):  
Science Fiction ◽  
Central Place ◽  
The Novel ◽  
Reading Experience ◽  
Award Winning ◽  
The Rich ◽  
Everyday Reality ◽  
Insight Into

Abstract Rob van Essen’s award-winning novel The good son (2018) offers its readers a puzzling reading experience. It contains a tangle of storylines and seems to lack head or tail. This contribution aims to discover composition and meaning by analyzing various aspects provided by the novel itself: timeline, plot, science fiction, ideas, poetica. This approach provides insight into the rich reservoir of meanings, whereby the importance of imagination and creation appears to have a central place. The novel, which can be labelled as a dystopian science fiction novel, as well as a novel of ideas or a novel of poetics, wants us to become aware of the mysteriousness of everyday reality. Nederlandstalig abstract Rob van Essens bekroonde roman De goede zoon (2018) biedt de lezers een verwarrende leeservaring. De roman bevat een wirwar aan verhaallijnen en heeft op het eerste gezicht nauwelijks samenhang. In deze bijdrage wordt geprobeerd compositie en betekenis te ontdekken door middel van een analyse van verschillende aspecten die uit de roman zelf naar voren komen: tijdsverloop, plot, sciencefiction, ideeën, poëtica. Daarmee ontstaat inzicht in een rijk reservoir aan betekenissen waarin het belang van scheppen en verbeelden een centrale plaats heeft. De roman, die beschouwd kan worden als een dystopische sciencefictionroman maar ook als een ideeënroman of een poëticale roman, lijkt ons te willen doordringen van de raadselachtigheid van de alledaagse werkelijkheid.

scholarly journals Effects of kefir consumption on carbohydrate profile of mother’s milk

2021 ◽  
Vol 11 (9) ◽  
pp. 473
Author(s):  
Tuğçe Tok Kurt ◽  
Çağlar Gökırmaklı ◽  
Zeynep B Guzel-Seydim
Keyword(s):  
Immune System ◽  
Human Milk ◽  
Control Group ◽  
Birth Mothers ◽  
Pathogenic Organism ◽  
Liquid Chromatographic Method ◽  
Mother's Milk ◽  
Mother’S Milk ◽  
The Rich ◽  
Liquid Chromatographic

Background: Human milk contains the nutrients necessary for the growth and development of babies as it contains essential bioactive components to support the immune system. Galactooligosaccharides which are important indigestible prebiotics, help multiply the growth of beneficial microorganisms selectively and inhibit the growth of the pathogenic organism. The nutrition of the mother is essential since it affects the composition of mother’s milk. Kefir affects the digestive system, lactose intolerance immune system, anti-microbial effects, probiotic and prebiotic features. However, there is no report on how kefir consumption may have effects on composition of mother’s milk. In this aspect, this study aimed to determine the effects of kefir consumption on the carbohydrate profiles of the mother’s milk. Methods: This study started immediately after birth, mothers were fed with 500 ml/day of kefir made from kefir grains for 30 days in the KF group. Mothers who are in the control group (KI) continued their regular diet. Mother’s milk was collected on the 10th, 20th, and 30th day and stored at 4ºC. Carbohydrate profile including GOS was determined using the liquid chromatographic method with the HI-PLEX column.Results: The mean lactose concentrations of mother’s milk who consumed kefir were 4,68; 4,72; 5,89 g/100ml on days 10th, 20th, and 30th, respectively. Glucose concentrations were 0,29; 0,08; 0,21 g/100ml on 10th, 20th, 30th days, respectively. For the mother’s milk samples in the control group, the averages of lactose concentration were 5,42; 5,73; 5,51 g/100ml on days 10th, 20th, and 30th. GOS peaks were specified depending on the rich content of prebiotics. Conclusion: Consumption of authentic kefir may have effect on carbohydrate profile, including GOS of mother’s milk. Keywords: Human milk, kefir, prebiotic, galactooligosaccharides  

scholarly journals ‘And I still see their faces…’: Wilhelm von Blandowski’s photographs from the collection of Museum in Gliwice

2009 ◽  
Vol 121 (1) ◽  
pp. 155
Author(s):  
Leszek Jodliński
Keyword(s):  
Natural World ◽  
Human Condition ◽  
Personal Interest ◽  
Promised Land ◽  
The Poor ◽  
Main Emphasis ◽  
History Of ◽  
The Rich ◽  
Early Photography ◽  
Insight Into

Wilhelm von Blandowski (1822-1878) was born in Gleiwitz, Prussia (now Gliwice, Upper Silesia, Poland). From 1862 through 1868, Wilhelm von Blandowski may have taken up to 10, 000 photographs. Though only a portion of his photographic accomplishment has been preserved, the existing photographs provide an insight into their content and character, as well as providing us with the better understanding of the work of their author. The main emphasis in the paper will be on Blandowski’s photographs presently in the collections of Museum in Gliwice. It will focus on his portraits with reference to some of the formal experiments Blandowski carried out, such as photomontage and narrative photography. Attention will be also drawn to his creation of documentary-like and realistic photographs. Both the commercial nature of the photographic business run by Blandowski, as well as his personal interest in picturing the human condition, had a strong influence on his photography. He put the person at the center of his interest. This was reflected in Blandowski’s attempts to capture the natural world of the Prussian borderlands in the 1860s. Blandowski depicted a place inhabited by Germans, Jews and Poles ‘the promised land’ of early industrialization. Witnesses of these days, the known and anonymous characters look at us from the hundreds of prints taken by Blandowski. Among them one can see wealthy industrialists, priests and doctors, workers and peasants, children and women, the rich and the poor, persons of different professions, nationalities and confessions. The article concludes with a discussion of the influences that Blandowski has had on his contemporaries and also of his place in the history of early photography in Poland.

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