scholarly journals PENGARUH LATIHAN BEBAN PADA LANSIA TERHADAP KADAR TNF-α

2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Russell B. J. D. Kilapong ◽  
Siantan Supit ◽  
J. J. V. Rampengan

Abstract: In elderly, the biological function of the systems in human body will decrease. Physical exercise is a systematical and programmed exercise to increase the body function and skills. Overtraining will influence the inflammatory response marked by the release of proinflammatory cytokines inter alia TNF-α. This was an experimental study with a post test design. Respondents were elderly in Panti Werdha Bethania Lembean trained for physical exercise by using dumbbells of 1-2 kg for 10-15 minutes, 3 times a week. Of 25 respondents, before the physical exercise there were 4 respondents with TNF-α above normal level (>100 pg/ml) and 21 respondents within normal level (10-100 pg/ml). After the 5-week physical exercise, there were 21 respondents with decreased TNF-α level and 4 respondents with increased TNF-α level. Moreover, there were no elderly with TNF-α level <10 pg/ml before and after physical exercise. Conclusion: Among elderly in Panti Werdha Bethania Lembean the averages of TNF-α level before and after physical training were within normal limit. However, there was a decrease of the average level of TNF-α after physical training.Keywords: physical training, elderly, TNF-αAbstrak: Pada lanjut usia (lansia), setiap individu akan mengalami penurunan fungsi biologis dari berbagai sistem dalam tubuh. Latihan fisik merupakan suatu aktivitas yang dilakukan secara sistematis dan terencana dalam meningkatkan fungsional tubuh dan keterampilan. Latihan olahraga berat akan merangsang respon inflamasi yang ditandai dengan pelepasan sitokin pro-inflamasi antara lain TNF-α. Penelitian ini bersifat eksperimental dengan rancangan post test design. Penelitian dilakukan terhadap lansia di Panti Werdha Bethania Lembean selama 5 minggu. Latihan beban 1-2 kg selama 10-15 menit dilakukan 3 kali seminggu. Dari 25 responden, sebelum latihan beban terdapat 4 orang dengan kadar TNF-α di atas batas normal (>100 pg/ml) dan 21 orang dalam batas normal (10-100 pg/ml). Setelah melakukan latihan beban terdapat 21 responden dengan penurunan kadar TNF-α dan 4 responden dengan kenaikan kadar TNF-α. Sebelum dan sesudah latihan beban tidak terdapat responden dengan kadar TNF-α <10 pg/ml. Simpulan: Pada lansia Panti Werdha Bethania Lembean rerata kadar TNF-α sebelum dan sesudah latihan beban masih dalam batas normal. Walaupun demikian, terdapat penurunan rerata kadar TNF-α sesudah latihan beban.Kata kunci: latihan beban, lansia, TNF-α

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Chytra Rachmat ◽  
Shane H.R. Ticoalu ◽  
Djon Wongkar

Abstract: A common form of dyslipidemia is often associated with cardiovascular disease which is hypertriglyceridemia. Triglycerides in the body is mainly used as energy storage for a variety of metabolic processes. Poco-poco gymnastics from North Sulawesi. The purpose of this study is to find out the influence of poco-poco gymnastics to triglyceride blood levels. Methods: This study is experimental using one group pre and post test design, the subjects were 25 female students year 2013 Science and Mathematic Faculty of Pharmacyof Sam Ratulangi University Manado who met the inclusion criterias. Data was analyzed using paired t test. Results: Based on the research that has done from 25 subjects it was obtained that there was a decrease in mean triglyceride levels before and after poco-poco gymnastics for four weeks. However, this decrease was not significant (p=0,366). Conclusion: There was a decrease in triglyceride levels after poco-poco exercises for four weeks but this is not significant.Keywords : poco-poco gymnastics, triglycerideAbstrak: Bentuk umum dislipidemia yang sering dikaitkan dengan penyakit kardiovaskuler yaitu hipertrigliseridemia. Trigliserida dalam tubuh terutama dipakai untuk menyediakan energi berbagai proses metabolik. Salah satu faktor yang dapat mempengaruhi kadar trigliserida yaitu olahraga. Senam poco-poco merupakan senam yang berasal dari Sulawesi Utara. Penelitian ini bertujuan untuk mengetahui pengaruh senam poco-poco terhadap kadar trigliserida darah. Metode: Penelitian ini bersifat eksperimental dengan rancangan one group pre and post test dengan jumlah subjek penelitian 25 mahasiswi Program Studi Farmasi Fakultas MIPA Universitas Sam Ratulangi Manado yang memenuhi kriteria. Data dianalisis dengan uji t berpasangan. Hasil: Berdasarkan penelitian yang dilakukan pada 25 subjek penelitian diperoleh hasil yaitu terjadi penurunan rata-rata kadar trigliserida sebelum dan sesudah senam poco-poco selama empat minggu. Namun penurunan ini secara statistik tidak bermakna (p=0,366). Simpulan: Terjadi penurunan kadar trigliserida setelah latihan senam poco-poco selama empat minggu namun penurunan ini secara statistik tidak bermakna.Kata Kunci: senam poco-poco, trigliserida


2013 ◽  
Vol 5 (1) ◽  
Author(s):  
Willem R. Matindas ◽  
Siantan Supit ◽  
Joice N. A. Engka

Abstract: Physical exercise can influence body metabolism. The Harvard test is  a simple method used in determining physical fitness. This test is performed by stepping up and down on a bench for certain periods of times. This study aimed to compare the levels of blood glucose of medical students of Sam Ratulangi University aged 20-22 years before and after performing the Harvard test. This was a field experimental study with One Group Pre-Post Test Design. The respondents were 35 students consisting of 22 males and 13 females who met the inclusion criteria. They were instructed to perform the Harvard test for five minutes and then were examined for blood glucose levels. The data were analyzed by using a t-test. The results showed an increase of the mean blood glucose levels from 75.80 mg/dL (before acute physical exercise) to 77.71 mg/dL (after acute physical exercise), but it was not statistically significant (P > 0.05). Conclusion: The acute physical exercise (the Harvard test) had no effect on before or after-exercise blood sugar levels. Keywords: acute physical exercise, Harvard test, blood sugar level    Abstrak: Latihan fisik dapat mempengaruhi metabolisme tubuh. Harvard test merupakan latihan fisik berupa naik turun bangku yang dilakukan dalam kurun waktu tertentu. Penelitian ini bertujuan untuk membandingkan kadar gula darah sebelum dan sesudah diberikan latihan fisik akut (Harvard test) pada mahasiswa Fakultas Kedokteran Unsrat dengan kisaran usia 20-22 tahun. Jenis penelitian ini bersifat eksperimental lapangan dengan rancangan One Group Pre-Post Test Design. Subyek penelitian sebanyak 35 mahasiswa, terdiri dari 22 laki-laki dan 13 perempuan yang memenuhi kriteria inklusi. Semua subyek diberikan latihan fisik akut (Harvard test) selama lima menit dan kemudian dilakukan pemeriksaan kadar gula darah. Data statistik di analisis mengunakan uji-t. Hasil penelitian memperlihatkan terjadinya peningkatan rerata kadar gula darah dari 75,80 mmHg (sebelum latihan fisik akut) menjadi 77,71 mmHg (sesudah latihan fisik akut) yang secara statistik tidak bermakna (P > 0,05). Simpulan:  Latihan fisik akut (Harvard test) tidak memengaruhi kadar gula darah  sebelum dan sesudah latihan. Kata kunci: latihan fisik akut, Harvard test, kadar gula darah.


2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Yusnia Jayanti

Abstract: The modern technology brings negative impact to human life that is the lack of physical activity which is not good for health and can cause varieties of diseases. Some studies show that lack of physical activity can lower pulmonary resistance and also a major cause of morbidity and mortality. Zumba is a Latine-inspired danse workout first developed in Columbia. The improvement of respiratory muscle endurance is gained from physical exercise . One asessment is a measurement of lung function FEV1 ( Forced expiratory volume in one Second ) which can provide information on the maximum rate of air flow in the lung. This study have a purpose to find out the influence of zumba exercise against FEV1 value of female students year 2013 Medical Faculty of Nursing Science Sam Ratulangi University hwo with less of physical or sport activities and meet the inclusion criteria. This was an experimental study with one group pre and post test design. Data was analyzed by paired t test using SPSS. The results showed significant differences between the average values of FEV 1 before and after 2 weeks of zumba exercise with P = 0,044 (P < 0.05). Conclusion: There was an increase of FEV 1 value after 2 weeks of Zumba exercise.Keywords: physical exercise, FEV1, Zumba.Abstrak: Kemajuan teknologi moderen membawa dampak negatif bagi masyarakat yaitu Kurangnya aktifitas fisik yang dapat berdampak buruk bagi kesehatan yaitu timbulnya berbagai penyakit. Beberapa penelitian menunjukkan berkurangnya aktifitas fisik dapat menurunkan daya tahan paru serta merupakan penyebab utama morbiditas dan mortalitas. Zumba merupakan latihan tari Latin yang terinspirasi pertama kali dan dikembangkan di Columbia. Peningkatan daya tahan otot pernapasan dapat diperoleh dari latihan fisik. Salah satu penilaian fungsi paru adalah pengukuran FEV1 (Forced Expiratory Volume in one Second) yang dapat memberikan informasi tentang laju aliran udara maksimal dalam paru. Penelitini ini ber tujuan untuk mengetahui pengaruh latihan zumba terhadap nilai FEV1 pada Mahasiswi Program Studi Ilmu Keperawatan angkatan 2013 Universitas Sam Ratulangi yang kurang melakukan aktivitas fisik atau olahraga dan memenuhi kriteria. Metode penelitian ini bersifat eksperimental dengan rancangan one group pre and post test design. Data dianalisis dengan uji t berpasangan menggunakan SPSS. Hasil penelitian ini menunjukkan perbedaan signifikansi antara nilai rata-rata FEV1 sebelum dan setelah 2 minggu latihan zumba P = 0,04 (P < 0,05). Simpulan: Terdapat peningkatan nilai FEV1 sesudah 2 minggu latihan zumba.Kata kunci : aktifitas fisik, FEV1, Zumba.


2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Indah Pramita ◽  
Mr Setiawan ◽  
Saifudin Zuhri

<p>ABSTRAK<br />Kasus stroke banyak dijumpai di lapangan, dimana penanganan pada pasien pasca stroke hanya menitik beratkan pada kemampuan motorik dan kurang memperhatikan kontrol postural. Sedangkan pada pasien pasca stroke memiliki masalah dengan kontrol postural yang berfungsi mengontrol posisi badan agar tetap tegak. Adanya masalah tersebut menghambat gerakan pada pasien pasca stroke dan mengakibatkan bertambahnya gangguan keseimbangan. Penelitian ini bertujuan untuk mengetahui manfaat latihan stabilisasi postural terhadap perbaikan keseimbangan statis dan dinamis pada pasien pasca stroke. Rancangan penelitian one group pre-test and post-test design dengan sampel sebanyak 6 orang yang diberikan latihan stabilisasi postural sebanyak 3x/minggu selama 1 bulan. Hasil Penelitian FRT sebelum perlakuan didapatkan rerata±SD sebesar 19,67±6,28 sedangkan rerata±SD FRT setelah perlakuan sebesar 25,50±5,28 dan p=0,004 (p&lt;0,05). Hal ini menunjukkan ada pengaruh antara latihan stabilisasi postural terhadap keseimbangan statis pada pasien pasca stroke. Hasil TUG test sebelum perlakuan didapatkan rerata±SD sebesar 31,17±1,82 sedangkan rerata±SD TUG test setelah perlakuan sebesar 18,50±5,17 dan p = 0,027 (p &lt; 0,05). Data ini juga menunjukkan ada pengaruh antara latihan stabilisasi postural terhadap keseimbangan dinamis pada pasien pasca stroke. Latihan stabilisasi postural meningkatkan keseimbangan statis dan dinamis pada pasien pasca stroke.<br />Kata kunci: Latihan, Keseimbangan , Stroke<br />ABSTRACT Many cases of stroke in the field, where the handling of post-stroke patients only focuses on motor skills and lack of attention to postural control. While in post-stroke patients have problems with postural control that controls the position of the body to remain upright. The existence of these problems hamper the movement in post-stroke patients and lead to increased disturbance of balance. This study aims to know the benefits of postural stabilization exercises to improve static and dynamic balance in patients with post stroke. This was an experimental pre using the design of a one group pre-test and post-test design. The number of subjects as many as 6 people, get as much 3x/minggu postural stabilization exercises for 1 month. Result of FRT before treatment obtained a mean ± SD of 19.67 ± 6.28 while the mean ± SD FRT after treatment for 25.50 ± 5.28 and p = 0.004 (p &lt;0.05). It shows atients with post stroke. Results TUG test before and after treatment. TUG test results obtained before treatment the mean ± SD of 31.17 ± 1.82 while the mean ± SD TUG test after treatment for 18.50 ± 5.17 and p = 0.027 (p &lt;0.05). It means there is influence between postural stabilization exercises on dynamic balance in patients with post stroke.The postural stabilization exercises enhance static and dynamic balance in patients with post stroke.<br />Keywords: Exercise, balance, Stroke</p>


2017 ◽  
Vol 4 (2) ◽  
pp. 14
Author(s):  
Putri Megasari

Hepatitis has become a health problem in the world. The hepatitis virus infected many people. According to the teacher of MTsN 02 Bondowoso more than 20 students have hepatitis A viral infection. The purpose of this research was to know the differences of students' knowledge about hepatitis A before and after counseling in MTsN 02 Bondowoso 2015. This study used pre-experimental (pre-post test design). This study used stratified random sampling technique, 127 students from 270 sample involved this research,and 143 students was excluded. We used questionnaires to collect data. The results showed that the mean value of the students 'knowledge about hepatitis A before counseling in MTsN 02 Bondowoso 2015 was 83.96 with the lowest value of 37.5 and the highest value was 100. The mean value of the students' knowledge about hepatitis A after counseling in MTsN 02 Bondowoso 2015 was 93.21 with the lowest value waf 62.5 and the highest value was 100. Paired t test showed that t (-9.07) > t table (1.98), the null hypothesis (H0) was rejected. There was a difference between students' knowledge about hepatitis A before and after counseling in MTsN 02 Bondowoso 2015. This study showed that routine counseling by healthcare provider was important to prevent hepatitis A infection.; Keywords: counseling, knowledge of students, hepatitis


2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Titin Dwi Ernawati ◽  
Nikhen Fitrianingtyas Harni ◽  
Jinnani Firdausiyah

ABSTRAKWanita muda cenderung memiliki perilaku buruk pada kebersihan selama menstruasi. Ketika reproduksi basah dan basah, maka akan meningkatkan keasaman memfasilitasi pertumbuhan jamur. Kondisi seperti gatal pada vulva, area eksternal biasanya terjadi pada wanita muda di masa menstruasi. Perilaku seseorang dipengaruhi oleh tingkat pendidikan dan pengetahuan. Pengetahuan seseorang tentang sesuatu dapat menyebabkan perubahan perilaku. Tujuan penelitian ini adalah untuk menganalisis efektivitas pendidikan kesehatan dengan metode ceramah dalam merawat kebersihan vulva terhadap perilaku kebersihan vulva saat menstruasi pada wanita muda di kelas VII di SMPN 1 Gondang Mojokerto.Jenis penelitian ini adalah pre eksperimental One Group Pre-Post Test Design. Populasi adalah wanita muda di kelas VII di SMPN 1 Gondang Mojokerto. Teknik pengambilan sampel menggunakan total sampling dan diperoleh 21 sampel wanita muda. Alat ukur yang digunakan dalam penelitian ini adalah kuesioner. Analisis data dengan membandingkan perilaku rata-rata memperlakukan kebersihan vulva selama menstruasi sebelum dan sesudah kuliah pendidikan kesehatan.Hasil penelitian sebelum pengobatan (pre-test) menunjukkan nilai rata-rata 9,000 sedangkan penelitian setelah perawatan (post test) menunjukkan nilai rata-rata 14,190. Ada perubahan dalam perilaku rata-rata memperlakukan kebersihan vulva selama menstruasi wanita muda sebelum dan sesudah kuliah pendidikan kesehatan di 5.190.Berdasarkan hasil pendidikan kesehatan dengan metode ceramah efektif untuk meningkatkan perawatan perilaku untuk kebersihan vulva selama menstruasi pada wanita muda. Kuliah pendidikan kesehatan tentang kebersihan vulva dapat digunakan sebagai salah satu cara efektif untuk memperbaiki perilaku kebersihan yang buruk selama menstruasi pada wanita muda.Kata kunci: pendidikan kesehatan, perilaku, kebersihan vulva ABSTRACTYoung women tend to have bad behavior on hygiene during menstruation. When reproduction moist and wet, it will increase the acidity facilitate mold growth. Conditions such as itching of the vulva, the external area usually occurs during young women in the menstrual period. Person's behavior is influenced by the level of education and knowledge. One's knowledge about something can cause behavioral changes. The purpose of the study was to analyze the effectiveness of health education with the lecture method of treating vulva hygiene on the behavior of vulva hygiene during menstruation in young women in class VII at SMPN 1 Gondang MojokertoType of research is pre experimental One Group Pre-Post Test Design. The population was young women in class VII at SMPN 1 Gondang Mojokerto. Sampling technique used total sampling and obtained 21 samples of young women. Measurement tool used in the study was questionnaire. Analysis of the data by comparing the average behavior of treating vulva hygiene during menstruation before and after the health education lecture.The results of the study before treatment (pre-test) showed a mean value of 9,000 while the study after treatment (post test) showed a mean value of 14,190. There is a change in the average behavior of treating vulva hygiene during menstruation young women before and after the health education lecture at 5,190.Based on the results of health education with the lecture method effectively to improved behavioral care for vulva hygiene during menstruation in young women. Health education lecture about hygiene vulva can be used as one of the effective ways to improve the behavior of poor hygiene during menstruation in young women.Key Words: health education, behaviour, vulva hygiene 


2021 ◽  
Vol 10 (1) ◽  
pp. 80-87
Author(s):  
Ari Indra Susanti ◽  
Aminarista Aminarista ◽  
Neneng Martini ◽  
Nur Rahmah ◽  
Sri Astuti

Background: Lactating mothers were successful in giving exclusive breastfeeding as much as 42% based on SDKI (Survei Demografi Kesehatan Indonesia) in 2012. This is depend on the support of husbands and families as well as health workers. Thus, the husband or family should remind and motivate mothers as well as monitor the breastfeeding activity every day for 6 months using breastfeeding calendar.Objectives: This study aimed to determine the increase in knowledge and attitudes of mothers in providing exclusive breastfeeding after the exclusive breastfeeding calendar training.Materials and Methods: The research design used a quasi-experimental one group pre-test post-test design. This research was conducted on mothers who had babies (age 0-12 months) in Pasawahan Village and Pasawahan Kidul Village, Pasawahan District, Purwakarta Regency in April to November 2018, with 96 respondents. The sampling technique was conducted by purposive sampling. Data were collected by giving questionnaires to respondents, before and after the breastfeeding calendar training were given. The Wilcoxon test was used for the analysis of the data in this study.Results: The results showed that there were differences in the knowledge of mothers before and after training on breastfeeding calendar (p <0,000) and there were differences in the attitudes of mothers before and after the training on breastfeeding calendar (p <0,000).Conclusions: There was an increase in knowledge and changes in the attitude of mothers towards exclusive breastfeeding after being given the breastfeeding Calendar training. Therefore, suggestions for health workers, especially midwives and nutrition workers, can use the breastfeeding calendar as an educational medium to increase husband and family support in exclusive breastfeeding.


2019 ◽  
Vol 2 (1) ◽  
pp. 47-59
Author(s):  
Widya Pribadiyanti Areski ◽  
Muzdalifah Muhammadun ◽  
Amzah Selle

This research aims to see the students’ speaking skill before and after learning process by using expression card media at the second grade of SMA Negeri 1 Parepare. The results of the research are useful for the teacher and students. The teacher should aware that it is important to supplied the technique or strategy before teaching and the students also can be easier to express their ideas, make the students more active in learning process. The subject of this research is XI IIS4 class which is consisted of 30 students. The sample was taken by using simple random sampling. The design in this research was pre-experimental with pre-test and post-test design. The student did the pre-test, got the treatment and did the post-test. Then the criteria of speaking skills are fluency, accuracy, content, pronunciation and they were usedto measure the students’ speaking skill. It aimed to know whether using expression card media can improve the students’ speaking skill. The result in this research was indicated that there was improvement of the students’ speaking skill. It was indicated by the students’ mean score of post-test (73.3) was greater than pre-test (41.9). Even, for the level significant (p) 5% and (df) = N-1=30-1=29, and the value of table is 1.699, while the value of t-test is 16.18. it means that, the t-test value is greater than t-table (16.18 ≥ 1.699). Thus, it can be concluded that the students’ speaking skill is significant better after getting the treatment. So, the null hypothesis (H0) is rejected and the alternative hypothesis (Ha) is fail rejected.


e-GIGI ◽  
2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Febri Korompot ◽  
Krista V. Siagian ◽  
Damajanty H. C. Pangemanan ◽  
Johanna Khoman

Abstract: The most common periodontal disease is gingivitis which is caused by biofilm accumulation on plaque around the gingival margin and inflammatory response to bacteria. Scaling is used to eliminate bacterial and calculus deposits that cause gingivitis. This study was aimed to determine the effectiveness of scaling in gingivitis treatment. This was a pre-experimental study with one group pre and post test design. Samples were obtained by using total sampling technique. There were 30 patients aged 17-45 years that had scaling performed on them at RSGM in 2019. Gingivitis was observed before and after scaling using the modified gingival index (MGI). The results showed that before scaling, there were mild gingivitis 23.30%, moderate gingivitis 70%, and severe gingivitis 6.70%. Two days after scaling, mild gingivitis and moderate gingivitis were observed 50% each. The paired sample t-test showed a p-value of 0.000. In conclusion, scaling is effective in gingivitis treatment based on the assessment using the modified gingival index.Keywords: gingivitis, scaling, modified gingival index Abstrak: Penyakit periodontal yang paling sering dijumpai yakni gingivitis (peradangan gingiva). Gingivitis disebabkan oleh akumulasi biofilm pada plak di sekitar margin gingiva dan respon peradangan terhadap bakteri. Tindakan untuk menghilangkan deposit bakteri dan kalkulus yang menyebabkan gingivitis salah satunya ialah tindakan skeling. Tujuan penelitian ini untuk mengetahui efektivitas tindakan skeling terhadap perawatan gingivitis. Jenis penelitian ialah pra eksperimental dengan one grup pre and post test design. Pengambilan sampel menggunakan teknik total sampling terhadap pasien yang berusia 17-45 tahun yang dilakukan tindakan skeling di RSGM pada tahun 2019 berjumlah 30 orang. Penelitian ini dilakukan dengan melihat gingivitis sebelum skeling dan setelah skeling melalui pengukuran keparahan gingiva menggunakan modified gingival index (MGI). Hasil penelitian menunjukkan bahwa sebelum skeling gingivitis ringan 23,30%, gingivitis sedang 70%, gingivitis berat 6,70%. Dua hari pasca skeling didapatkan gingivitis ringan dan gingivitis sedang sama besar yaitu masing-masing 50%. Hasil uji t berpasangan menunjukkan nilai p=0,000. Simpulan penelitian ialah tindakan skeling efektif terhadap perawatan gingivitis berdasarkan penilaian modified gingival index.Kata kunci: gingivitis, skeling, modified gingival index


2010 ◽  
Vol 35 (3) ◽  
pp. 261-269 ◽  
Author(s):  
Kristen M. Beavers ◽  
Monica C. Serra ◽  
Daniel P. Beavers ◽  
Matthew B. Cooke ◽  
Darryn S. Willoughby

Aging is associated with increasing inflammation and oxidative stress in the body, both of which can have negative health effects. Successful attenuation of such processes with dietary countermeasures has major public health implications. Soy foods, as a source of high-quality protein and isoflavones, may improve such indices, although the effects in healthy postmenopausal women are not well delineated. A single-blind, randomized controlled trial was conducted in 31 postmenopausal women who were assigned to consume 3 servings of soy (n = 16) or dairy (n = 15) milk per day for 4 weeks. Parameters of systemic inflammation (tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6)) and the oxidative defense system (superoxide dismutase (SOD), glutathione peroxidase, cyclooxygenase-2) were measured post supplementation, before and after an eccentric exercise bout performed to elicit an inflammatory response. A significant group-by-time effect for plasma TNF-α was observed (p = 0.02), with values in the dairy group increased post supplementation and then decreasing into the postexercise period. Additionally, significant time effects were observed for plasma SOD (p < 0.0001) and IL-6 (p < 0.0001) in the postexercise period. Overall results from our study do not support the notion that 4 weeks of daily soy milk ingestion can attenuate systemic elevations in markers of inflammation or oxidative defense. However, data do suggest that the downhill-running protocol utilized in this study can be effective in altering systemic markers of inflammation and oxidative defense enzyme activity, and that the ingestion of soy may help prevent fluctuations in plasma TNF-α.


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