scholarly journals Comparative assessment of the effect of the combined use of Feliferon and Azoxivet and Globfel-4 in feline rhinotracheitis on hematological parameters of white blood

Author(s):  
G. A. Nozdrin ◽  
L. P. Ermakova ◽  
I. K. Mensh ◽  
Ya. E. Borodina ◽  
S. N. Tishkov

The comparative effect of the combined drugs Feliferon and Azoksivet and the drug Globfel-4 for rhinotracheitis in felines on hematological parameters of white blood was studied. In our study on the treatment of viral rhinotracheitis, 16 cats were examined. During the experiment, all cats showed the following clinical signs: lethargy, fever, leakage from the eyes and nasal passages. The animals were kept in separate cages in accordance with the European Convention for the Protection of Vertebrates. The control group was given 1 ml subcutaneously, once a day every other day, with a course of 7 injections, immunoglobulin against rhinotracheitis, calicivirus and chlamydia - Globfel-4. The experimental group was treated with drugs Azoxivet intramuscularly in a course of 7 injections, once a day every other day, and Feliferon at a dose of 400,000 IU intramuscularly, once a day. The course of treatment was 7 days. Blood sampling was performed from the anterior saphenous vein of the forearm before and after therapy. The concentration of erythrocytes and hemoglobin was determined on an automatic hematology analyzer Mindray BC-2800. When treating cats with rhinotracheitis with Globfel-4, pronounced leukocytosis, absolute and relative lymphocytosis were noted. With the combined use of Azoxivet and Feliferon, these blood changes do not occur. When treating cats with rhinotracheitis with Globfel-4 or the combined use of Azoxivet and Feliferon, the absolute concentrations of monocytes and granulocytes increase within the physiological norm. The relative concentrations of these white blood phrases increase within the physiological norm only with the combined use of Azoxivet and Feliferon.

2022 ◽  
Vol 42 ◽  
pp. 01027
Author(s):  
Alexey Trebukhov ◽  
Elena Shaganova ◽  
Yulia Chekunkova ◽  
Nadezhda Momot ◽  
Yulia Kolina

Use of biologically active additives in feeding young animals is the most important element of resource-saving technologies. The aim of the study was to study the effectiveness of use of vitamin and mineral nutrition on the growth and development of young animals. 3 groups of calves were formed at the age of 10 days. Animals of the control group received the basic diet (OR), the II-experimental group received OR + salts of microelements and the calves of the III-experimental group received OR + salts of microelements and tetratwit in doses from 1 to 3 months – 1.5 mg, from 3 to 5 months – 2.0 mg and from 5 to 6 months – 3.0 mg. Tetravit was injected once every 2 weeks throughout the study. It was found that feeding the salts of microelements (copper, zinc, cobalt, manganese, iodine) to calves during the dairy period contributes to their more intensive development and growth of their meat productivity, both in combination with tetravite and without it. Use of salts of microelements separately, and in combination with a multivitamin preparation (tetravit) contributes to a significant increase in the studied hematological parameters in young animals, relative to control analogues.


2019 ◽  
pp. 47-50
Author(s):  
L.A. Nikanova

Приведены данные по изучению эффективности применения антиоксиданта дигидрокверцетина Экостимул2 и пребиотика арабиногалактана. Включение в рацион поросятотъёмышей дигидрокверцетина (50 мг/гол/день) и арабиногалактана (5 г/гол/день) положительно повлияло на гематологические показатели крови, биохимические показатели сыворотки крови, антиоксидантную защиту и продуктивность поросят. После завершения эксперимента живая масса поросят в опытной группе была на 10,6 выше, чем в контрольной. Совместное применение дигидрокверцетина и арабиногалактана положительно сказалось и на сохранности поголовья, которая в опытной группе составила 100, в контрольной группе 90. Количество лейкоцитов в крови поросят опытной группы было ниже на 8,0, а эритроцитов выше на 1,5 по сравнению с этими показателями у поросят контрольной группы, что отразилось на содержании гемоглобина и гематокрита крови. У поросят, получавших кормовые добавки, кислотное число, перекисное число и СЖК было ниже, чем у контрольных животных на 19,8, 20,5 и 19,7 соответственно. С этими показателями корреспондируется антиокислительная активность сыворотки крови, которая при применении кормовых добавок была выше на 26,5, чем в контроле. Кормовые добавки профилактировали гипербилирубинемию. В результате концентрация общего билирубина в плазме крови поросят опытной группы была ниже на 13,9, активность АлАТ и АсАТ в сыворотке их крови также была ниже на 18,7 и 17,6, чем в контроле. В сыворотке крови у поросят опытной группы содержание холестерина было выше на 1,8 мМ/л, чем в контроле, что характеризует состояние холестеринообразовательной функции печени. Содержание же глюкозы в крови у них было в пределах физиологической нормы и находилось на уровне 5,44 мМ/л, в то время как у поросят контрольной группы её содержание составляло 6,67 мМ/л (выше физиологической нормы) и могло свидетельствовать о повышенной функции коры надпочечников и, в связи с этим, наличии глюконеогенеза.The data on studying of the use effectiveness of the antioxidant dihydroquercetin Ecostimul2 and the prebiotic arabinogalactan are presented. The inclusion of dihydroquercetin (50 mg/goal/day) and arabinogalactan (5 g/goal/day) in the diet of weaned piglets had a positive effect on blood hematological parameters, serum biochemical parameters, antioxidant protection and piglet productivity. After the experiment the live weight of piglets in the experimental group was 10.6 higher than in the control one. The combined use of dihydroquercetin and arabinogalactan positively affected the safety of the livestock which in the experimental group was 100, in the control group 90. The number of leukocytes in the blood of the piglets of the experimental group was 8.0 lower and the erythrocytes were higher by 1.5 compared to these indicators in the piglets of the control group which was reflected in the content of hemoglobin and blood hematocrit. In piglets receiving feed additives the acid number, peroxide number, and FFA were lower than in control animals by 19.8, 20.5, and 19.7 respectively. These indicators correspond to the antioxidant activity of blood serum which was 26.5 higher when using feed additives than in the control. Feed additives prevented hyperbilirubinemia. As a result the concentration of total bilirubin in the blood plasma of piglets of the experimental group was 13.9 lower, the activity of AlAT and ASAT in their blood serum was also lower by 18.7 and 17.6 than in the control. The cholesterol content in the blood serum of piglets from the experimental group was 1.8 mol/L higher than in the control which characterizes the state of the cholesterolforming function of the liver. The glucose content in their blood was within the physiological norm and was at the level of 5.44 mol/L while in the piglets of the control group its content was 6.67 mol/L (higher than the physiological norm) and could indicate an increased function of the adrenal cortex and in connection with this the presence of gluconeogenesis.


2018 ◽  
Vol 9 (01) ◽  
Author(s):  
Praful Prabhuappa Kapse ◽  
Manisha Kiran

Caring for the persons with first episode psychosis is challenging and demanding. It may lead to the increased burden, expressed emotions among the caregivers. The numerous studies have shown that high burden and negative expressed emotions among caregivers can lead to early relapse in the patients with first episode psychosis. To evaluate the effects of the brief psychoeducation on the caregivers burden and expressed emotions. A quasi experimental - before and after with control group research design was adopted for the study. A total of 60 caregivers have participated in the study, of which 30 caregivers in experimental group and 30 caregivers in the control group. Family Burden Interview Schedule (Pai and Kapoor, 1981) and Attitude Questionnaire (Sethi et al., 1981) was used to assess caregiver's burden and expressed emotions. At end of the psychoeducation intervention, burden among caregivers and negative expressed emotions of the caregivers have significantly reduced. The positive expressed emotions have been increased. Study results demonstrates the importance of psychoeducation intervention in reducing the burden and negative expressed emotions.


Healthcare ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 820
Author(s):  
Ju-Yong Bae ◽  
Hee-Tae Roh

We aimed to investigate the effect of Taekwondo training on physical fitness, mood, sociality, and cognitive function among international students in South Korea. We randomly assigned 24 international students to a control group (CG, n = 12) and experimental group (EG, n = 12). The EG performed Taekwondo training for 16 weeks, while the CG did not train. Each participant underwent a physical fitness test and sociability questionnaire before and after the intervention. We also examined changes in mood state and cognitive function, using the Korean version of the Profile of Mood State-Brief (K-POMS-B), and the Stroop Color and Word test, respectively. Regarding the physical fitness variables, sit-and-reach records in the EG significantly increased after intervention (p < 0.05). In the sub-variable of K-POMS-B, Vigor-Activity scores significantly increased (p < 0.05) after intervention, while the Fatigue-Inertia scores significantly decreased in the EG (p < 0.05). Furthermore, in the EG, peer relationship scores, a sub-variable of sociability, significantly decreased after intervention (p < 0.05). These findings suggest that Taekwondo training can not only improve flexibility among physical fitness factors, but can also be effective in improving the mood state and sociality of international students.


2021 ◽  
Vol 38 (9) ◽  
pp. A4.2-A4
Author(s):  
Matthew Warren-James ◽  
Julie Hanson ◽  
Belinda Flanagan ◽  
Mary Katsikitis ◽  
Bill Lord

BackgroundWhilst there is evidence to suggest paramedics experience significant stress when working in the ambulance setting little is known about the experiences of first year paramedic students. This research aimed to: (i) identify whether levels of stress, anxiety and depression experienced by first year paramedic students changed after ambulance placement compared to a control group, and (ii) identify the main perceived and actual sources of stress around ambulance placement.MethodsA before-and-after quasi-experimental design was used to compare whether the experience of ambulance placement altered the levels of stress, anxiety and depression in an experimental group that attended an ambulance placement (n = 20) and the control group who did not (n = 10). Online surveys encompassing the Depression, Anxiety and Stress Scale (DASS-21) and qualitative questions about sources of stress were concurrently deployed to both the experimental and control groups before and after the ambulance placement. Participants were first year paramedic students working in Queensland Ambulance Service, Australia.ResultsThere was a significant reduction in levels of stress in participants after undertaking their first ambulance placement (Mdn = -4.00) when compared to a control group (Mdn = 0.00), U = 52.5, p = .035, n2 = 0.15. Responses to survey questions suggest anticipation about experiencing death and dying of patients was the most frequently reported stressor of student paramedics before undertaking ambulance placements, however insecurity about knowledge, competence and fear of failure was the most frequently experienced stressor reported after completing ambulance placements.ConclusionsThe findings from this study suggest that the fear of the unknown may be worse than the reality. Anticipatory stress is the foremost problem for first year paramedic students attending their first ambulance placement. Placement pre-briefing should focus on educational interventions to build knowledge and skills competency to reduce stress levels and fear of failure.


Author(s):  
D. Skafar ◽  
D. Shumeyko

Purpose: to study the effect of ethanol on the parameters of THC, the percentage of granulocytes and total protein in the hemolymph of the Red claw crayfish (Cherax quadricarinatus).Materials and methods. The object of this experiment was 26 males of the Australian red-clawed crayfish (Cherax quadricarinatus) weighing from 23 to 83 g. The individuals were evenly divided into two experimental groups - with an injection of ethanol and a control group without an injection of 13 crayfish for each group. The injection dose was 2515 mg per 100 g of body weight. A day after the introduction of ethanol, hemolymph was taken with a syringe from the ventral sinus, the syringe was pre-washed with a 4% EDTA-Na2 solution. Three parameters were determined: the total hemocyte count (THC), percent granulocytes and percent total protein content. Counting of hemocytes and determination of granulocytes were performed in a Goryaev chamber under a light microscope. The total protein was determined by the refractometric method.Results. Differences in THC and total protein between the groups were statistically unreliable (p>0,05). THC in the experimental group is 36% more than in the control group. The total protein after the introduction of ethanol actually increased by 0,7%, and relatively by 14%. There were statistically different indicators of the proportion of granulocytes (p<0,05) - the average value of 33,1% in the experimental group versus 24,5% in the control group. A reliable (p<0,05) strong feedback was revealed between the total protein and the mass of individuals in both experimental groups, while in the experimental group there is a visible shift in the values of dependent hemolymph indicators towards an increase in smaller individuals.Conclusion. A single injection of ethyl alcohol with a dosage of 2515 mg per 100 g of body weight into the hemolymph of C. quadricarinatus does not cause significant changes in the THC and total protein after 24 hours. At the same time, the proportion of granulocytes actually increases by 9%, relative to 37%. This may indicate that granulocytes are involved in the formation of cancer defense mechanisms when exposed to toxic substances. The effect of different dosages of ethanol injections and the duration of its effect on hematological parameters requires additional consideration. It is necessary to investigate its effect on other indicators, such as the pH and buffer capacity of the hemolymph, the concentration of hemocyanin, glucose, lactates and calcium.


2018 ◽  
Vol 71 (3) ◽  
pp. 967-974 ◽  
Author(s):  
Radamés Boostel ◽  
Jorge Vinícius Cestari Felix ◽  
Carina Bortolato-Major ◽  
Edivane Pedrolo ◽  
Stela Adami Vayego ◽  
...  

ABSTRACT Objective: To evaluate and compare the perception of stressors by nursing students before and after a high-fidelity clinical simulation or conventional laboratory practice class. Method: This is a randomized clinical trial conducted with 52 nursing students. Both groups had theoretical classes about cardiothoracic physical examination, followed by practice class in skill laboratory. In addition, the experimental group took part in a high-fidelity simulation scenario. Stressors were evaluated before and after class, with the application of KEZKAK questionnaire. Results: The experimental group was significantly more worried about six factors related to lack of competence and to interpersonal relationships (p < 0.05), while the control group was significantly more worried about being in contact with suffering (p = 0.0315). Conclusion: The simulation affects students’ perception of stressors and promotes their self-evaluation and critical thinking regarding the responsibility that comes with their learning.


2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Mario Bertini ◽  
Elena Isola ◽  
Giuseppe Paolone ◽  
Giuseppe Curcio

The study aims at evaluating health-generating function of humor therapy in a hospital ward hosting children suffering from respiratory pathologies. The main scope of this study is to investigate possible positive effects of the presence of a clown on both the clinical evolution of the on-going disease, and on some physiological and pain parameters. Forty-three children with respiratory pathologies participated in the study: 21 of them belonged to the experimental group (EG) and 22 children to the control group (CG). During their hospitalization, the children of the EG interacted with two clowns who were experienced in the field of pediatric intervention. All participants were evaluated with respect to clinical progress and to a series of physiological and pain measures both before and after the clown interaction. When compared with the CG, EG children showed an earlier disappearance of the pathological symptoms. Moreover, the interaction of the clown with the children led to a statistically significant lowering of diastolic blood pressure, respiratory frequency and temperature in the EG as compared with the control group. The other two parameters of systolic pressure and heart frequency yielded results in the same direction, without reaching statistical significance. A similar health-inducing effect of clown presence was observed on pain parameters, both by self evaluation and assessment by nurses. Taken together, our data indicate that the presence of clowns in the ward has a possible health-inducing effect. Thus, humor can be seen as an easy-to-use, inexpensive and natural therapeutic modality to be used within different therapeutic settings.


2019 ◽  
pp. 1-2
Author(s):  
S. Neelavathy ◽  
R. P. Balasubramania

Emotion is the ability of a person to express the state of mind which he is, but when a person is mentally, physically, emotionally, and spiritually unstable results in a psychological change and helpless on situations. The purpose of the study was to nd out Effect of SKY yoga and pranayama on emotion among college girls .To achieve the purpose of the study 45 College girls were selected randomly from Coimbatore as the subjects. The subject's age ranged from 18 to 21 years. . The selected subjects were divided into 3 groups. Experimental Group I under went on sky yoga only & Experimental Group II went on pranayama only for 50 minutes per day, six days a week for 12 weeks. The control group was not given any practice. The pre-test and post-test were conducted before and after the training for all three groups. The data collected from the groups before and after the training period were statistically analysed by using Analysis of Co-Variance (ANACOVA) to determine the signicant difference and tested at 0.05 level of signicance. The result of the study showed that there was signicant improvement in the emotion of the Experimental Groups I, II subjects than the Controlled group. Through the SKY yoga and Pranayama Emotion got controlled. The conclusion was that SKY yoga controlled emotions and got reduced the psychological effects depression and stress etc. among college girls.


2020 ◽  
Vol 2 (3) ◽  
pp. 229-236
Author(s):  
Yela Purnama Sari ◽  
Herman Lusa ◽  
Ansyori Gunawan

This study aimed to find the effect of using monopoli game media towards learning result on social science major at fourth grade of SDN Gugus 15 Kota Bengkulu. This research is quantitative, using experiment method, with The Matching Only Pretest-Posttest Control Group Design. The instrument used was test sheet in multiple choice form. The test was taken two times, before and after giving treatening to the sample class. The sample in this research was the students in IVB of SDN 76 Kota Bengkulu (control group) and the students in IV of SDN 104 Kota Bengkulu (experimental group). The t value gotten was (3,668) > ttable (1,668). The result of t value was higher than t table, so it can be concluded that there are significant effect of using monopoli game media towards learning result on social science major at fourth grade SDN Gugus 15 Kota Bengkulu.


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