scholarly journals A Review of Recent Studies on The Phytochemical and Pharmacological Activity of Annona Muricata

2021 ◽  
Vol 2 (1) ◽  
pp. 1-5
Author(s):  
Dr. T. Kumaran

Medicinal plants have been used to treat illness and disease for thousands of years. Bioactive principles present in medicinal plants attribute to the therapeutic efficacy and it can be incorporated into modern medicine systems for the development of newer drug formulation for therapeutic ailments. Even now they are economically important, being used in the pharmaceutical, cosmetic, perfumery, and food industries. Screening of medicinal plants for antimicrobial activities and phytochemicals is important for finding potential new compounds for therapeutic use. In the present review, an attempt has been made to congregate the traditional, phytochemical, and pharmacological studies done on an important medicinal plant Annona muricata. Cyclo hexapeptides, acetogenins, annonaceous acetogenins were the major phytochemical compounds studied from this medicinal plant. The fruit is of economic value and hence cultivated and used widely as edible food. The plant possesses the major pharmacological activities includes Anti-viral activity, Anti-oxidant Activity, Larvicidal activity, Anti-inflammatory activity, Antipediculicidal activity, Anti-bacterial activity, and wound healing. It also has an anti-carcinogenic and cytotoxic effect.

2017 ◽  
Vol 11 (1) ◽  
pp. 352-359 ◽  
Author(s):  
Gemechu Ameya ◽  
Aseer Manilal ◽  
Behailu Merdekios

Background: Controlling infectious disease using medicinal plants is the oldest healthcare known to mankind. Regardless of the enormous advances observed in modern medicine, medicinal plants are still playing vital roles. However, only a small proportion of medicinal plants are examined for bioactive compounds which may vary in different factors. This study aimed to evaluate phytochemical constituent and antimicrobial activities of Nicotiana tabacum L. extracted by different solvents against three set of bacteria. Methods: Nicotiana tabacum L. was collected from the Western Ethiopia and extracted in seven organic solvents. An in-vitro anti-bacterial activity of plant extracts was carried out by agar well diffusion assay against microbial type culture collection of human pathogens, clinical bacterial isolates, and biofilm forming bacteria. Gas Chromatographic and Mass Spectroscopic (GC-MS) analysis was used to determine the phytochemical constituents. Results: Antimicrobial activities of plant extract vary by extraction solvents; and ethyl acetate based extracts showed better antimicrobial activities. Of the experimental organisms, biofilm forming uropathogens were the most sensitive while clinical isolates were quite resistant. Analysis of the active ethyl acetate extract by GC-MS evinced a mixture of five volatile compounds; and Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S) was the major compound detected. The overall results of the present study revealed that N. tabacum L extract has high antimicrobial activities against biofilm forming uropathogens. Conclusion: High antimicrobial activity was observed in ethyl acetate extract of N. tabacum against the biofilm forming bacteria whereas the clinically isolated bacteria were the most resistant group. The antibacterial property demonstrated could be due to Pyridine, 3-(1-methyl-2-pyrrolidinyl)-(S) with a broad spectrum of activity.


2020 ◽  
Vol 5 (2) ◽  
pp. 294-299
Author(s):  
Rosmini ◽  
Sri Anjar Lasmini ◽  
Andi Ete ◽  
Dwi Rohma Wulandari ◽  
Nur Edy ◽  
...  

The cultivation of rare and or wild medicinal plants is one of the strategies to make it easier when needed and also to produce quality simplicia. The partner village program aims to assist the community in carrying out medicinal plant cultivation. The community service activities were carried out in the conservation area of ​​medicinal plants and in the residents' yards in Pakuli Village and lasted for 4 months, from March 2020 to July 2020. The method applied was counseling and technical guidance. The results of the activities showed that the training and technology demonstration were well implemented and were accepted by the community. Counseling activities increase knowledge that is characterized by increased skills when practicing medicinal plants. Species that are cultivated in conservation areas are those that grow wild and rare, while in people's yards it is the species most widely used as medicine and which is of economic value.  


Plants ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 44 ◽  
Author(s):  
Jedidah Nankaya ◽  
Nathan Gichuki ◽  
Catherine Lukhoba ◽  
Henrik Balslev

The use of medicinal plants for treatment of humans and animals is entrenched in the Maasai culture and traditional knowledge related to it is passed on from one generation to the next. A handful of researchers have in the past decades documented this knowledge. No single study has documented medicinal plant uses of the Maasai community as a whole. This review provides a consolidated database of the diversity and uses of medicinal plants among the Maasai in Kenya. The study will help conserve traditional medicinal plant knowledge that is valuable for the development of modern medicine. Relevant information on medicinal plants used by the Maasai of Kenya was extracted from journals, books, M.Sc., and Ph.D. dissertations. We found evidence of 289 plant species used by the Maasai of Kenya in traditional medicine. Most species were used to treat health conditions in the categories gastrointestinal and respiratory system disorders. The most used families were Leguminosae, Asteraceae, Malvaceae, Euphorbiaceae, and Lamiaceae. Medicines were commonly prepared as a decoction and administered through oral ingestion, with roots reported to be the preferred plant part for medication. The Maasai preference for roots compared to other plant parts may be unsustainable and could threaten species availability in the future.


2017 ◽  
Vol 10 (3) ◽  
pp. 19 ◽  
Author(s):  
Miki Toda ◽  
Misa Masuda ◽  
Elsa L. Rengifo

Medicinal plants, as a type of non-timber forests (NTFP), have been expected to support the livelihoods of people globally, especially in rural and forest areas in developing nations. As medicinal plants occupy a unique position, with direct repercussions for people’s health and as a potential income resource, it is necessary to take the interaction with, and influence of, modern medicine into account when they are considered as a NTFP. This study pursued the influence of the health care service on medicinal plant utilization in mestizo and indigenous villages near secondary population agglomerations in the Peruvian Amazon. The study found some influence of the health care services on medicinal plant use in the study site, indicating that 1) medicinal plants are not necessarily a highly dependable approach for health care, 2) there are insufficient conditions for the development of a commercial market for medicinal plants, and 3) mestizo and indigenous households have similar health care utilization behaviours, although indigenous households are more affected by modern medicine, especially health care insurance, than the mestizo households. The health care service is an important factor for medicinal plant use for both health and livelihood. Without considering this factor, the potential of medicinal plants as NTFP cannot be fully understood.


2016 ◽  
Vol 01 (01) ◽  

Medicinal plant products are characterized by the presence of several bioactive (primary and secondary metabolites) constituents that are present. Phytochemical (qualitative and quantitative analysis) and immunopharmacological based studies may provide new compounds in the form of drugs for eliminating intracellular as well as extracellular infections. Several immunopharmacological based reports have shown the action of medicinal plant products and its constituents (i.e. primary and secondary metabolites) against various pathogens i.e. cancer, inflammation, diabetes etc.


2021 ◽  
Author(s):  
Richard James Faber ◽  
Charles Petrus Laubscher ◽  
Muhali Olaide Jimoh

Sceletium tortuosum is a succulent plant that belongs to the family Mesembryanthemaceae (Aizoaceae). It is indigenous to South Africa, where it is well known by the indigenous people, especially in Namaqualand where the plant is utilized regularly for its medicinal and psycho-active properties. The main alkaloids responsible for these properties are mesembrine, mesembrenine (mesembrenone), and mesembrenol. The potential of the plant to be an alternative supplement in the promotion of health and treating a variety of psychological and psychiatric disorders such as depression and anxiety has stimulated interest in its pharmacological property and possibility of its commercialization. The economic value of indigenous medicinal plants in South Africa is approximately US$60 000 000 or R4 000 000 000 annually. Thus, interest in the knowledge and use of Traditional African Medicinal Plants (TAMP) as well as meeting pharmacological and economic needs of ever-increasing human population has led to the commercialization of traditional African medicines at a fast rate. It was found that S. tortuosum has clear pharmaceutical and economical importance and is one of the only known plants to contain the alkaloids mesembrenone and mesembrine which can be utilized for the promotion of health and/or treating a variety of psychological disorders such as anxiety and depression.


2012 ◽  
Vol 2012 ◽  
pp. 1-15 ◽  
Author(s):  
Sofia Zank ◽  
Natalia Hanazaki

We investigated the knowledge of medicinal plants in two areas proposed for the creation of protected areas for sustainable use in the city of Imbituba (SC). In this study, we analyzed the influence of gender, form of learning, and modern medicine on medicinal plant knowledge while also reflecting on the relationship of this knowledge toin situconservation. Data collection was conducted through structured interviews, free listings, guided tours, and collection of botanical material. 197 species of medicinal plants belonging to 70 botanical families were recorded. Gender and the form of learning were factors that significantly influenced the similarity of the knowledge of medicinal plants among the informants. We also observed the existence of a therapeutic pluralism among key informants. Local medicinal plant knowledge emphasizes the importance of strategies to create protected areas of sustainable use as a way to ensure the maintenance of traditional lifestyles and associated local knowledge.


2021 ◽  
Vol 3 (1) ◽  
pp. 40
Author(s):  
Vally T. T. Fatti ◽  
Poppy M. Lintong ◽  
Maria K. Sambuaga

Abstract: The utilization of medicinal plants in Indonesia has been going on for generations even before modern medicine began to be marketed. Although its properties are widely known, but certain medicinal plants can give toxic effects to the liver. This study was aimed to re-evaluate the hepatotoxic effects of medicinal plants and changes in liver morphology. This was a literature review study using databases of Pubmed, ClinicalKey, and Google Scholar. The results obtained five medicinal plants that had hepatotoxic effects. Areca catechu showed morphological changes in the form of hemorrhagic, sinusoid dilation, lobular inflammation, lobular disarray, necrosis, interface hepatitis, microsteatosis, hepatocellular cholestasis, and steatosis. Myrmecodia pendans showed the presence of fat degeneration, necrosis, and inflammatory cell infiltration. Annona muricata indicated the presence of hepatocyte swelling. Gynura divaricata showed increases of SGOT and SGPT levels. Vernonia amygdalina Del showed the presence of cellular degeneration and necrosis of hepatocytes. In conclusion, the most diverse morphological changes of liver are caused by Areca catechu along with large dose consumption meanwhile the most minimal morphological changes of the liver are caused by Annona muricata.Keywords: herbal medicine; hepatotoxic effect  Abstrak: Pemanfaatan tanaman obat di Indonesia telah berlangsung selama turun-temurun bahkan sebelum obat modern mulai dipasarkan. Meskipun khasiatnya telah banyak diketahui, namun tanaman obat tertentu dapat memberikan efek toksik pada hati. Penelitian ini bertujuan untuk mengevaluasi kembali efek hepatotoksik tanaman obat dan perubahan morfologik hati. Jenis penelitian ialah literature review, menggunakan database Pubmed, ClinicalKey, dan Google Scholar. Hasil penelitian ini mendapatkan lima jenis tanaman obat yang bersifat hepatotoksik. Areca catechu menunjukkan adanya perubahan morfologik berupa perdarahan, dilatasi sinusoid, inflamasi lobular, lobular disarray, nekrosis, interface hepatitis, mikrosteatosis, kolestasis hepatoseluler, dan steatosis. Myrmecodia pendans menunjukkan adanya degenerasi lemak, nekrosis, dan infiltrasi sel radang. Annona muricata menunjukkan adanya pembengkakan hepatosit. Gynura divaricata menunjukkan adanya peningkatan kadar SGOT dan SGPT. Vernonia amygdalina Del menunjukkan adanya degenerasi dan nekrosis hepatosit. Simpulan penelitian ini ialah perubahan morfologik hati yang paling beragam disebabkan oleh Areca catechu seiring dengan besar dosis yang dikonsumsi sedangkan perubahan morfologik hati yang paling minimal disebabkan oleh Annona muricata.Kata kunci: tanaman obat; efek hepatotoksik


2021 ◽  
Vol 2 (2) ◽  
pp. 72-82
Author(s):  
Syardiansah Syardiansah ◽  
Ayu Artlinta

The purpose of training the development of family medicinal plants through the participation of the community in Kampung Seuriget, Langsa Barat Subdistrict is to increase the interest of the community to be able to utilize vacant land around the house or yard so as to produce better use value for daily use from the value of family medicinal plants. economical. This training activity involved villagers as suspicious as especially housewives. The implementation of this training involved partners, namely the Seuriget Health Center in West Langsa District. The training method uses the apprenticeship method (direct guidance and work). The family medicinal plant development training was carried out from 7 February 2017 to 10 April 2017 with details of the activities including: making land for cultivation, plant nurseries and planting medicinal plants. The results obtained by the training participants were that they had begun to be able to prepare the land for the crops in the house and to grow crops according to the type of medicinal plants they were interested in. Furthermore, it is expected that the results of this family medicinal plant can be further processed to be able to become food ingredients or other types of processed products of economic value, not just limited to drugs.


2021 ◽  
Vol 10 (13) ◽  
pp. e355101321410
Author(s):  
Antonio Fávero de Carvalho ◽  
Allívia Rouse Carregosa Rabbani ◽  
Sheila Valéria Álvares-Carvalho ◽  
Renata Silva-Mann

The use of plants with medicinal properties for fungi control has led to a continuous exploration of new compounds that could contribute towards promising studies in the development of new drugs and the knowledge of how this control is performed on microorganisms. The objective of this review has been to report on the potential use of medicinal plants to control the pathogenic fungi of a host of plants and animals, which can contribute to the achievement of new formulations for botanical fungicides. Many authors have demonstrated antifungal and general antimicrobial activities for Brazilian flora species through well-established methods, such as by microdilution, agar diffusion, and disk diffusion, while determining a minimum inhibitory concentration (MIC), minimum fungicidal concentrations (MFC), and the inhibition potential of essential oils, extracts and fractions. In this review, 68 species were cited for occurring in Brazil, with 25 being in the north-northeastern part of the country. Thus, most studies about the antimicrobial activities of medicinal plants bring an ‘initial understanding’ of their potential, particularly of some species, genera, and even families. Nevertheless, more data that is exceedingly specific is mandatory by focusing on new and more accurate approaches, such as the action mechanisms, toxicity, the active components, and the verification of the existence of synergic effects. These criteria would be the minimum required to develop new natural products as alternative treatments for the various infectious pathologies that affect plants, animals, and human beings.


Sign in / Sign up

Export Citation Format

Share Document