Substantiation of the development of technology for industrial production of B vitamins

2022 ◽  
pp. 37-41
Author(s):  
Максим Валерьевич Марченок ◽  
Егор Олегович Рочин ◽  
Марина Всеволодовна Палагина ◽  
Людмила Александровна Текутьева
Keyword(s):  
Chemical Synthesis ◽  
Industrial Production ◽  
Information Sources ◽  
B Vitamins ◽  
Schematic Diagram ◽  
Nutrient Media ◽  
Advantages And Disadvantages ◽  
Producer Strains

Проведен анализ информационных источников по существующим технологиям получения витаминов B и B. Кратко описаны преимущества и недостатки известных технологий с использованием различных штаммов-продуцентов, а также технологий с использованием химического синтеза. Предложена принципиальная схема разрабатываемых технологий синтеза данных витаминов, определены наиболее продуктивные штаммы-продуценты и необходимые компоненты питательных сред. Обоснован и представлен перечень продуктов, предназначенных для обогащения витаминами группы В, которые будут получены по разрабатываемым технологиям. The analysis of information sources on existing technologies for obtaining vitamins B and B has been carried out. The advantages and disadvantages of known technologies using various producer strains, as well as technologies using chemical synthesis, are briefly described. A schematic diagram of the developed technologies for the synthesis of these vitamins is proposed, the most productive strains - producers and necessary components of nutrient media are identified. The list of products intended for enrichment with B vitamins, which will be obtained by the developed technologies, has been substantiated and presented.

scholarly journals Carotenoids Functionality, Sources, and Processing by Supercritical Technology: A Review

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Natália Mezzomo ◽  
Sandra R. S. Ferreira
Keyword(s):  
Chemical Synthesis ◽  
Organic Solvents ◽  
Industrial Production ◽  
Raw Materials ◽  
Biological Properties ◽  
Alternative Technique ◽  
Carotenoid Production ◽  
Conventional Process ◽  
Major Development

Carotenoid is a group of pigments naturally present in vegetal raw materials that have biological properties. These pigments have been used mainly in food, pharmaceutical, and cosmetic industries. Currently, the industrial production is executed through chemical synthesis, but natural alternatives of carotenoid production/attainment are in development. The carotenoid extraction occurs generally with vegetal oil and organic solvents, but supercritical technology is an alternative technique to the recovery of these compounds, presenting many advantages when compared to conventional process. Brazil has an ample diversity of vegetal sources inadequately investigated and, then, a major development of optimization and validation of carotenoid production/attainment methods is necessary, so that the benefits of these pigments can be delivered to the consumer.

scholarly journals Information Sources and Training Needs on Medical Marijuana- Preliminary Results from a State-wide Provider Survey

2021 ◽  
Author(s):  
Ruba Sajdeya ◽  
Jennifer Jean-Jacques ◽  
Anna Shavers ◽  
Yan Wang ◽  
Nathan Pipitone ◽  
...  
Keyword(s):  
Information Sources ◽  
Medical Marijuana ◽  
Training Needs ◽  
The State ◽  
Research Articles ◽  
Medical Conditions ◽  
Specific Detail ◽  
Advantages And Disadvantages ◽  
Online Sources ◽  
And Training

Medical marijuana (MMJ) is legal in the state of Florida for the treatment of specific qualifying medical conditions.1,2 As of July 2020, over 2,450 physicians are authorized to order MMJ, and 360,000 patients are registered in Florida’s MMJ program.3 With this rapid uptake come concerns regarding physicians’ knowledge about MMJ,4–7 and the lack of preparing physicians-in-training to manage MMJ.4,7,8 We conducted a state-wide survey of certified MMJ providers in Florida. The survey was developed by the Consortium for Medical Marijuana Clinical Outcomes research team. The aim of the survey was to inform physicians of the mission of the consortium, which is to support and disseminate research. The survey items were developed accordingly, and the survey was pilot tested with a small group of physicians. We identified all physicians licensed to certify patients for MMJ who care currently practicing in the State of Florida (n=1609), to investigate their information sources and training needs regarding MMJ. The survey was disseminated via mail and email, including a $40 incentive for survey completion. Preliminary responses from 51 (5%) providers (mean age 56, 74% male) are summarized here. The sample included providers from 22 Florida counties and represented a broad range of medical specialties. The majority (92%) practiced in both medical marijuana and traditional medical practice. To learn about MMJ, 98% used research articles, 90% used online sources, 86% learned from dispensary staff, 84% learned from discussions with other providers, 72% used books, 65% used conferences, 61% used magazines, and 35% had a personal experience with marijuana. The sources most cited as “very useful” were conferences (51%), research articles (50%), discussions with other providers (47%), and online sources (47%). Topics rated as a high priority for training included drug-MMJ interactions (80%), strategies to help patients reduce their use of opioids or other drugs (80%), information about the selection of doses and CBD: THC ratios (80%), evidence for managing specific medical conditions or symptoms (78%), information about the effect of different phytocannabinoids and terpenes (75%), advantages and disadvantages of specific modes of delivery (71%), general updates on research findings (71%), educational information about the endocannabinoid system (67%), the safety of medical marijuana use (55%), identification and management of cannabis use disorder (51%), and comparison of products available in different dispensaries (49%). The majority of providers either strongly agreed or agreed (77%) that they could provide better care if they knew which products their patients receive at dispensaries. Physicians use a blend of primary research, online sources, and exchanges with colleagues to learn about MMJ. Perceived needs for more pharmacological information and indication-specific detail for treatment regimen were high. Most physicians believe that details on dispensed MMJ would improve patient care.

Midwestern organic farming: A ten-year follow-up

1987 ◽  
Vol 2 (2) ◽  
pp. 57-63 ◽  
Author(s):  
William Lockeretz ◽  
Patrick Madden
Keyword(s):  
Organic Farming ◽  
Information Sources ◽  
Financial Status ◽  
Advantages And Disadvantages ◽  
Organic Farmers ◽  
Synthetic Pesticides ◽  
Religious Considerations ◽  
Mailed Survey ◽  
Detailed Questionnaire

AbstractA mailed survey was sent to 174 Midwestern organic farmers originally studied in 1977. We obtained information on 133 of this group, 96 of whom are still farming at the same location, although 12 no longer use organic methods. Fifty-eight currently active farmers returned a detailed questionnaire that covered their perceptions of the advantages and disadvantages of organic farming, some of their practices, and their financial status. Most farmers who employed organic farming methods stated they did so out of concern for the health of themselves, their families, and their livestock. Compared to ten years ago, philosophical or religious considerations were less frequently mentioned as an advantage of organic farming. In contrast, some agronomic and management disadvantages of organic f arming were mentioned more often. The farmers now are more tolerant, in principle, of some chemicals not generally accepted in organic farming, but regular use of soluble fertilizers and synthetic pesticides has not increased appreciably. The farmers reported little change in the institutional and social environment for organic agriculture, including available markets, information sources, and the attitudes of their neighbors.

Analysis of Different Building Materials Used in Heritage Protected Areas in North China

2013 ◽  
Vol 357-360 ◽  
pp. 26-32
Author(s):  
Xiao Yu Zhang ◽  
Yong Qing Sun ◽  
Xu Lan ◽  
Jian Ming Bai
Keyword(s):  
Protected Areas ◽  
Industrial Production ◽  
Building Materials ◽  
North China ◽  
Chinese Law ◽  
Advantages And Disadvantages ◽  
Chinese Characteristics ◽  
Materials Used ◽  
Definition Of ◽  
Modern Building

This paper first reviews the definition of protected areas under Chinese law, and it pays attention to problems of using four types of building materials in protected areas: traditional building materials produced by old craftsmanship, traditional components collected from the torn down old buildings, antique-style building materials made from industrial production and well-designed modern building materials with Chinese characteristics. By elaborating on the four different selections of building materials, it analyses the advantages and disadvantages of each selection.

scholarly journals Progress in Enzymatic Biodiesel Production and Commercialization

Processes ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 355
Author(s):  
Liangliang Lv ◽  
Lingmei Dai ◽  
Wei Du ◽  
Dehua Liu
Keyword(s):  
Industrial Production ◽  
Chemical Process ◽  
Production Cost ◽  
Raw Materials ◽  
Biodiesel Production ◽  
Industrial Scale ◽  
Enzymatic Process ◽  
Advantages And Disadvantages ◽  
The Past ◽  
High Enzyme

Enzymatic biodiesel production has attracted tremendous interest due to its well-recognized advantages. However, high enzyme costs limit the application of enzymatic processes in industrial production. In the past decade, great improvements have been achieved in the lab and the industrial scale, and the production cost of the enzymatic process has been reduced significantly, which has led to it being economically competitive compared to the chemical process. This paper summarizes the progress achieved in enzymatic biodiesel research and commercialization, including reducing enzyme cost, expanding low-quality raw materials, and novel reactor designs. The advantages and disadvantages of different enzymatic processes are also compared.

Discussions on the Methods of Preventing Heat Transfer Fluids from Oxidation in Open Heating System Based on Liquid-Phase Organic Heat Transfer Fluids Heater

2014 ◽  
Vol 1070-1072 ◽  
pp. 1722-1726
Author(s):  
Guang Xiao Kou ◽  
Rong Rong Lu ◽  
Jing Hua Yang ◽  
Ling Ling Cai ◽  
Pei Na Shang
Keyword(s):  
Heat Transfer ◽  
Liquid Phase ◽  
Technological Process ◽  
Cooling Water ◽  
Heat Pipes ◽  
Heating System ◽  
Schematic Diagram ◽  
Heat Transfer Fluids ◽  
Advantages And Disadvantages ◽  
Cooling Coils

Introduces the technological process of the open heating system with a liquid-phase organic heat transfer fluids heater by analyzing the advantages and disadvantages of preventing heat transfer fluids from oxidation based on expansion pipe with cooling water casing. And it presents two methods to prevent heat transfer fluids from oxidation by arranging directly cooling coils or pulsating heat pipes in the expansion tank; it also provides the schematic diagram of those methods as well as comparatively analyzes their advantages and disadvantages.

Preparation and Research Advance of Electronic Grade Phosphoric Acid

2014 ◽  
Vol 881-883 ◽  
pp. 70-73
Author(s):  
Bin Wang ◽  
Kang Bi Luo
Keyword(s):  
Phosphoric Acid ◽  
High Purity ◽  
Industrial Production ◽  
Direct Method ◽  
Purification Method ◽  
Oxidation Method ◽  
Advantages And Disadvantages ◽  
Yellow Phosphorus ◽  
Research Advance

The application of high purity phosphoric acid in industrial production is more and more widely used, especially electronic grade phosphoric acid, and the demand of it has risen year by year. This paper introduces the preparation and research advance of electronic grade phosphoric acid, expounds the principle, advantages and disadvantages and research advance of preparing high purity phosphoric acid by high purity phosphorus oxidation method and phosphoric acid purification method. Using hot process by direct method to prepare high purity electronic grade phosphoric acid is still the mainstream on the current, and the key of technique is the purification of yellow phosphorus and phosphoric acid.

scholarly journals Future Benefits of Microorganism on Leather Defects in The Industrial Production of Protease

2021 ◽  
Vol 33 ◽  
pp. 02002
Author(s):  
Novita Kurniawati ◽  
Eka Lusiana ◽  
Nanung Agus Fitriyanto ◽  
Mohammad Zainal Abidin ◽  
Satyaguna Rakhmatulloh ◽  
...  
Keyword(s):  
Ambient Temperature ◽  
Industrial Production ◽  
Liquid Media ◽  
Isolation Method ◽  
Nutrient Media ◽  
Solid Media ◽  
Tanning Process ◽  
Microbial Isolates ◽  
Liquid Growth Medium

Article, pickle, and wet blue leather defects used for this study were fromthe Balai Besar Karet college, Kulit dan Plastik, D.I Yogyakarta (BBKKP YK), Indonesia. Meanwhile, the microorganisms in leather defects were grown in vitro at A-minimal mineral (MM) and B-lowest (1/200 v/v) nutrient media. A nitrogen source of 2% Sigma-Aldrich bovine gelatine was added to each medium. Furthermore, 1cm2 of each leather defect was sliced and immersed into the in vitro media for 7 days in an open-air rotary incubation with ambient temperature at 28° C to 30° C. The first or conventional method was the rubbing of ose cotton into the solid media, while the second isolation method was the centrifugationof liquid growth medium at 15.1G for 20 minutes. Moreover, the four microbial isolates were fromglossy yellow colonies A and B as wel as white colonies. These colonies were incubated at 38° C and the four microbes produce proteases after growing for at least 7days in liquid media and 24 hours less in solid media. The protease test produced gases on the pickle leather defects using a test tubeglass of 0.8cmdiameter and 15cmlong. Therefore, the chemical tanning process on leather defects creates a unique ecosystem of microorganisms as collagen proteins change and become thekeyto their growth.

scholarly journals Pyrazines Biosynthesis by Bacillus Strains Isolated from Natto Fermented Soybean

Biomolecules ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1736
Author(s):  
Grzegorz Kłosowski ◽  
Dawid Mikulski ◽  
Katarzyna Pielech-Przybylska
Keyword(s):  
Bacillus Subtilis ◽  
Chemical Synthesis ◽  
Organic Compounds ◽  
Food Industry ◽  
Total Concentration ◽  
Environmentally Friendly ◽  
Two Cultures ◽  
Efficient Producer ◽  
Bacillus Strains ◽  
Producer Strains

Pyrazines are organic compounds with a varied, intense aroma of roasted nuts, occasionally with hints of baked potatoes, almonds, and others. As a result, they are used in the food industry as food flavorings. Biosynthesis of pyrazines using microorganisms in environmentally friendly conditions is an alternative to chemical synthesis. However, screening is required to isolate efficient producer strains for efficient biosynthesis of this compound. The study’s goal was to assess the ability of Bacillus subtilis cultures isolated from natto (fermented soybeans) to biosynthesize a broad range of alkylpyrazines. B. subtilis isolated cultures were found to be capable of producing 2-methylpyrazine, 2,3-dimethylpyrazine, 2,5-dimethylpyrazine, 2,6-dimethylpyrazine, 2,3,5-trimethylpyrazine, and 2,3,5,6-tetramethylpyrazine. As a result of the screening, two cultures of B. subtilis capable of producing alkylpyrazines were isolated. At a total concentration of 3261 µg/L, the BcP4 strain primarily produced 2-methylpyrazine (690 µg/L), 2,3-dimethylpyrazine (680 µg/L), and 2,6-dimethylpyrazine (1891 µg/L). At a total concentration of 558 mg/L, the BcP21 strain produced 2,5-dimethylpyrazine (4.5 mg/L), 2,3,5-trimethylpyrazine (52.6 mg/L), and 2,3,5,6-tetramethylpyrazine (501.1 mg/L). The results show that different B. subtilis strains are predisposed to produce different alkylpyrazines.

scholarly journals Tax Control Methods for Transactions Between Mutually Dependent Persons: Advantages and Disadvantages

2018 ◽  
pp. 300-305
Keyword(s):  
Russian Federation ◽  
Information Sources ◽  
Transfer Pricing ◽  
Comprehensive Analysis ◽  
Optimal Pricing ◽  
Current Transfer ◽  
Control Methods ◽  
Basic Principles ◽  
Advantages And Disadvantages ◽  
The Russian Federation

The paper examines the methods defined by the Tax Code of the Russian Federation with regard to the tax control of transactions between interdependent persons. The authors of the paper reveal the basic principles of choosing a particular method of pricing in transactions between interdependent persons: the choice by the taxpayer of the optimal pricing method, which, with regard to all sides of the analyzed transaction, will give the most accurate and well-reasoned conclusion about the conformity of the price applied in the analyzed transaction to the market level; comprehensive analysis of the parties to the transaction taking into account the available data; general availability of information sources that allow information about comparable transactions to search for; the tax authority must justify and prove the impossibility of applying the previous transfer pricing method before proceeding to an analysis of the current transfer pricing method used in the transaction. The algorithms of application of each method, its advantages and disadvantages, as well as optimal economic situations for application of specific methods of pricing in transactions between interdependent persons are revealed. Based on the analysis carried out by the authors of the paper, a conclusion is made about the riskiness of applying methods of tax control of transactions between interdependent persons, since each method has inherent risks that can lead to a dispute between taxpayers and tax authorities.

Sign in / Sign up

Export Citation Format

Share Document