scholarly journals Cholinesterase and Liver Enzymes in Patients with Organophosphate Poisoning

2019 ◽  
Vol 8 (1) ◽  
pp. 33-37
Author(s):  
Prabodh Risal ◽  
Sandip Lama ◽  
Saroj Thapa ◽  
Rajendra Bhatta ◽  
Raj Kumar Karki
Keyword(s):  
Liver Enzymes ◽  
Laboratory Data ◽  
Retrospective Chart Review ◽  
Acute Hepatic Failure ◽  
Significant Negative Correlation ◽  
The Body ◽  
Phosphorus Compounds ◽  
Organophosphate Poisoning ◽  
P Value ◽  
Age Group

Background: Organ phosphorus compounds are one of the most common causes of insecticide poisoning worldwide leading to high degree of morbidity and mortality especially in the developing countries like Nepal. The liver is the main organ that metabolizes various compounds including toxins, chemicals and drugs and eventually excretes from the body. Few studies have been done in Nepal to see the level of liver enzymes among the organ phosphorus compounds poisoning. This may helps in early diagnosis of acute hepatic failure and reduces OP poisoning related death. Materials and Methods: Retrospective chart review study was done with organophosphate poisoning attending Emergency Department followed by admission to Medicine ward or ICU of Dhulikhel Hospital from April 2014 to September 2017. And, laboratory data was extracted from laboratory software, MIDAS version 3.2. After collection of data, statistical analysis was carried out using Statistical Package for Social Sciences (SPSS) version 21 software. Results: Majority of the patients with organophosphate poisoning were female with 64.8% and the majority (31.5%) of patient were of age group in the age group 16-25. Plasma cholinesterase level was found to be significantly decreased in the patients with organophosphate poisoning. Random blood sugar was significantly found to be raised in this study (125.77±52.3), p-value0.04. Among all liver enzymes, there is a significant negative correlation of Cholinesterase with AST (r = -0.35; p-value<0.05). Conclusion: This study showed that the level of liver enzyme do not correlate well in the cases of organophosphate poisoning except of AST, which has been raised significantly.

scholarly journals Relationship of Physical Activities with Nutrition Status in Students at SMK Negeri 1 Percut Sei Tuan Deli Serdang District

2020 ◽  
Vol 2 (1) ◽  
pp. 377-383
Author(s):  
Hasnizar ◽  
Evawany Aritonang ◽  
Etti Sudaryati
Keyword(s):  
Physical Activity ◽  
Nutritional Status ◽  
Quantitative Research ◽  
The Body ◽  
Nutrition Status ◽  
P Value ◽  
Age Group ◽  
Cross Sectional ◽  
Relationship Of ◽  
The Relationship

Adolescents are age group that is vulnerable to the nutritional problems. Factors that influence nutritional status in adolescents include physical activity. Physical activity including physical exercise which is one of the efforts to stabilize the intake and expenditure of food substances which is a priority source of energy in the body. The purpose of this study was to analyze the relationship of physical activity with nutritional status in students at SMK Negeri 1 Percut Sei Tuan, Deli Serdang District in 2019. The type of research used was quantitative research with cross sectional research design. The results obtained by the relationship of physical activity with the nutritional status of students p value of 0.003 or smaller than 0.05. The conclusion of the study is that there is a relationship of physical activity with nutritional status in students at SMK Negeri 1 Percut Sei Tuan. Students who are doing physical activity have normal nutritional status because there is a balance between energy intake and expenditure.

scholarly journals Liver Enzymes and Inpatient Deaths in COVID-19 Hospitalized Patients

2020 ◽  
Vol 20 (11) ◽  
Author(s):  
Mahmoodreza Khoonsari ◽  
Farhad Zamani ◽  
Mohammad Hadi Karbalaie Niya ◽  
Gholamreza Hemmasi ◽  
Hossein Ajdarkosh ◽  
...  
Keyword(s):  
Liver Enzymes ◽  
Laboratory Data ◽  
Hospitalized Patients ◽  
Liver Involvement ◽  
Common Finding ◽  
P Value ◽  
Gastrointestinal Involvement ◽  
Significant Difference ◽  
High Incidence ◽  
Independent Association

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [COVID-19] quickly turned into a pandemic. Gastrointestinal involvement, especially liver diseases, is one of the main complications of COVID-19 patients. Objectives: The current study aimed to evaluate the high incidence of liver involvement in COVID-19 hospitalized patients and its association with mortality. Methods: A total of 560 hospitalized patients with a confirmed diagnosis of COVID-19 were included. Death was considered as the outcome. In addition to liver enzymes, demographic, clinical, and other laboratory data were also collected. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels ≥ 40 were considered as abnormal. To investigate the association between abnormal levels of liver enzymes and death, multiple regression logistic was used. Results: According to the findings, 29.1% (95% CI = 25.3% - 32.9%) of patients had high levels (≥ 40 IU) of ALT, and 45.1% (95% CI = 40.9% - 49.3%) had high levels of AST (≥ 40 IU). The frequency (based on %) of high levels of AST (≥ 40 U/liter) was significantly higher in patients who died [67.3% (95% CI = 54.5% - 80.1%] of COVID-19 than those who survived [44.9% (95% CI = 39.7% - 50.0%)] (P-value < 0.001). No significant difference was detected in ALT between expired [29.1% (95% CI = 16.7% - 41.5%)] and survived patients [30.7% (95% CI = 25.9% - 35.5%] (P-value = 0.791). AST was found to have an independent association with death in multiple logistic regression (Wald = 4.429, OR (95% CI) = 1.014 (1.008 - 1.020), P-value = 0.035). Conclusions: Liver involvement is a common finding in COVID-19 hospitalized patients. Higher levels of AST were significantly associated with an increased mortality rate in COVID-19 patients.

scholarly journals Evaluation of Cephalic Index in children from the Madheshi community in Sarlahi district, Nepal

2021 ◽  
Vol 12 (10) ◽  
pp. 157-160
Author(s):  
Surendra Kumar Sah ◽  
Man Kumar Tamang ◽  
Om Prakash Yadav ◽  
Amit Kumar Shah
Keyword(s):  
Mode Of Delivery ◽  
Age Groups ◽  
Significant Negative Correlation ◽  
The Body ◽  
P Value ◽  
Cephalic Index ◽  
Cross Sectional ◽  
Chisquare Test ◽  
Low Bmi ◽  
The Mean

Background: Cephalic index is one of the important craniofacial parameters which is commonly used for investigating the length and breadth of the head. Cephalic Index (CI) is defined as the ratio between maximum breadth of the head and the maximum length of the head multiplied by 100. Body mass index (BMI) is a nutritional marker of the body derived from the measurement of height (in m2) and weight (in kg). Aims and Objective: To analyse the effect of BMI on the CI. Materials and Methods: This study was a cross-sectional study conducted from April 2021 to June 2021 with sample size of 200 children of age groups 5-8 years from Ramnagar Gaupalika of Sarlahi, Province 2, of Nepal. We measured the cephalic index of the children and asked a set of structured questionnaire to the guardian or parent of the children. Height and weight of the children were also measured and BMI was determined. Data analysis was completed using SPSS version 16. Results: The mean age of the participants was 6.56 years, BMI of 18.09 and cephalic index (CI) of 81.82. The mean CI in males and females were 82.05 and 81.59 respectively. Our results show significant association between BMI category and CI category (chisquare test, p-value=0.000), mode of delivery and BMI category (chisquare test, p=0.042) and significant negative correlation between BMI and CI (Pearson’s R=-0.591, p=0.037). Conclusion: The most common pattern of CI was hyperbrachycephalic in the children of low BMI whereas the pattern of CI in case of the normal BMI was the mesocephalic type. It also confirmed that the sexual dimorphism exists in both the low BMI and the normal BMI.

scholarly journals INTERRELATIONSHIP BETWEEN SATTVA SARATA AND EMOTIONAL INTELLIGENCE - AN OBSERVATIONAL STUDY

2020 ◽  
Vol 04 (04) ◽  
pp. 2303-2308
Author(s):  
Manisha Yadav ◽  
Srikanta Kumar Panda ◽  
Nishi Arora
Keyword(s):  
Emotional Intelligence ◽  
Problem Solving ◽  
Observational Study ◽  
The Body ◽  
Intelligence Test ◽  
P Value ◽  
Age Group

In Ayurveda, the “Sara” word is used for the Vishuddhatara Dhatu (Tissue excellence). Sara is essence of Dhatu which provides strength and stability to the body. Determination of Sara of a person gives a clue of one’s structural and metabolic characteristic as well as physical and mental disposition, which help to check out the line of treatment of a person and prescribing a favorable regimen and diet. Sattva Sara is the most purified form of Sattva. The present study aims at assessing Sattva Sarata and Emotional Intelligence. The participants of the study were included 60 subjects between age group of 16 to 30 years. A proforma, spe-cially designed on the basis of characteristics features describe in Brihattrayee for assess the Sattva Sarata. Emotional Intelligence was assessed by Mayer Salovey Caruso Emotional intelligence Test (MSCEIT). MSCEIT is based on a series of Emotion based problem solving items. Finding of the study revealed that the association in Sattva Sarata and Emotional Intelligence was statistically significant at (P value <0.05). Keywords: Sara, Sattva Sara, Emotional Intelligence

EPIDEMIOLOGY AND OUTCOMES OF ELECTRIC BURN INJURY AT TERTIARY CARE CENTER IN JODHPUR, RAJASTHAN

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Bharti Saraswat ◽  
Ashok Yadav ◽  
Krishna Kumar Maheshwari
Keyword(s):  
Burn Injury ◽  
Low Voltage ◽  
Care Center ◽  
Tertiary Care ◽  
The Body ◽  
Electrical Injury ◽  
Age Group ◽  
Electric Circuits ◽  
Medical College ◽  
Social Burden

Background- Electric burns and injuries are the result of electric current passing through the body. Temporary or permanent damage can occur to the skin, tissues, and major organs. Methods- This prospective study was carried out on patients admitted in burn unit of department of surgery M.G. Hospital associated with Dr. S.N. Medical College Jodhpur. Records of the patients admitted from January 2018 to December 2018 were studied. Bed head tickets of the patients evaluated in detail. Results- In our study out of 113 patients maximum no. of patients were in age group of 21-30 years 44 (38.94%) followed by age group <11 years in 21 (18.58%) patients and age group of > 60 years in only 3 (2.65%).39 (34.51%) patients were farmer and 15 (13.27%) were electrician in out of 113 total patients, while 37 (32.74%) were without any occupation. 65 (57.52%) cases of high voltage (HV) electrical injury and 48 (42.48%) cases were of low voltage (LV) electrical injury. Conclusion- Morbidity leading to permanent disabilities make the person physically dependent on others. It can be prevented by educating the people about the proper handling to electric circuits & devices. Proper communication among the electricians may help in lowering such accidents. Proper rehabilitation of the handicapped person & employment to the member of the affected family may reduce the social burden caused by such electricity concerned accidents.

Efektivitas Aroma Terapi Lemon untuk Menangani Emesis Gravidarum

2019 ◽  
Vol 11 (4) ◽  
pp. 277-284
Author(s):  
Vitrianingsih Vitrianingsih ◽  
Sitti Khadijah
Keyword(s):  
Pregnant Women ◽  
Sampling Technique ◽  
T Test ◽  
The Body ◽  
Nausea And Vomiting ◽  
P Value ◽  
Purposive Sampling ◽  
Body Tissues ◽  
Quasi Experimental ◽  
Paired T Test

Studi memperkirakan emesis gravidarum terjadi pada 50-90% kehamilan. Mual muntah pada kehamilan memberikan dampak yang signifikan bagi tubuh dimana ibu menjadi lemah, pucat dan cairan tubuh berkurang sehingga darah menjadi kental (hemokonsentrasi). Keadaan ini dapat memperlambat peredaran darah dan berakibat pada kurangnya suplay oksigen serta makanan ke jaringan sehingga dapat membahayakan kesehatan ibu dan janin. Salah satu terapi yang aman dan dapat dilakukan untuk mengurangi keluahan mual muntah pada ibu hamil adalah pemberian aromaterapi lemon. Penelitian bertujuan untuk mengetahui efektifitas aroma terapi lemon untuk menangani emesis gravidarum. Penelitian ini menggunakan rancangan Quasi experiment  dengan  one group pre-post test design. Populasi penelitian adalah ibu hamil yang mengalami emesis gravidarum di Kecamatan Berbah, Sleman. Jumlah sampel 20 ibu hamil trimester pertama yang diambil dengan teknik purposive sampling. Pengukuran mual muntah dilakukan debelum dan setelah  pemberian aromaterapi lemon menggunakan Indeks Rhodes. Analisa data menggunakan uji Paired t-test. Hasil penelitian didapatkan rata-rata skor mual muntah sebelum pemberian aromaterapi lemon berdasarkan Indeks Rhodes pada Ibu Hamil dengan emesis gravidarum yaitu 22,1 dan terjadi penurunan skor setelah pemberian aromaterapi lemon menjadi 19,8. Ada pengaruh pemberian aromaterapi lemon dengan pengurangan mual muntah pada ibu hamil (p-value = 0.017). Berdasarkan hasil penelitian dapat disimpulkan pemberian aromaterapi lemon efektif untuk mengurangi emesis gravidarum pada ibu hamil trimester pertama.  Kata kunci: aromaterapi lemon, emesis gravidarum THE EFFECTIVENESS OF LEMON AROMATHERAPY FOR HANDLING EMESIS GRAVIDARUM   ABSTRACT Studies estimate that nausea and vomiting (emesis gravidarum) occur in 50 – 90% of pregnancies. Nausea and vomiting of pregnancy have a significant impact on the body in which it makes a mother becomes weak, pale, and decreasing body fluid so that the blood becomes thick (hemoconcentration). This situation can slow down blood circulation and inflict the lack of oxygen and food supplies to the body tissues so that it can endanger the health of the mother and fetus. One of the therapies that is safe and can be conducted to reduce nausea and vomiting of pregnancy is by giving the lemon aromatherapy treatment. The research aims to determine the effectiveness of the aroma of lemon therapy to deal with emesis gravidarum. This study applied quasi-experimental research with one group pretest-posttest design. The population of this study was pregnant women who experienced emesis gravidarum. Furthermore, samples were 20 mothers from Berbah, Sleman taken by using a purposive sampling technique. Nausea and vomiting were assessed between before and after giving lemon aromatherapy using the Rhodes Index. The data were analyzed using the paired t-test. The mean score of nausea and vomiting before giving lemon aromatherapy on mother with emesis gravidarum based on the Rhodes Index was 22.1. However, it decreased after given lemon aromatherapy treatment to 19.8. Therefore, there was an effect on giving lemon aromatherapy treatment toward the decrease of nausea and vomiting for pregnant women (p-value = 0.017). Lemon aromatherapy is effective to reduce emesis gravidarum.  Keywords: lemon aromatherapy, emesis gravidarum

Hubungan Religiusitas dengan Citra Tubuh pada Wanita Dewasa Awal

2018 ◽  
Vol 1 (1) ◽  
pp. 9-28
Author(s):  
Dessy Sumanty ◽  
Deden Sudirman ◽  
Diah Puspasari
Keyword(s):  
Body Image ◽  
Correlation Coefficient ◽  
Research Design ◽  
Calculation Result ◽  
The Body ◽  
Statistical Testing ◽  
P Value ◽  
Significance Level ◽  
Correlational Research

This research attempts to relate the body image phenomenon with the level of subject religiosity. This research used correlational research design that was involving 332 respondents. The statistical testing which is used to test the hypothesis Rank Spearman. The calculation result with the significance level of trust 95% (a = 0.05) show that the correlation coefficient is 0.083 and p-value is 0.129. It means that Ho is accepted and H1 is rejected. It can be concluded that there is no relationship between religiosity with body image.

Kajian Kandungan Fe dalam Air Tanah Terhadap Kadar Ekskresi Yodium dalam Urin pada Anak Sekolah di Desa Cerme Kecamatan Panjatan Kabupaten Kulon Progo

2017 ◽  
Vol 19 (1) ◽  
pp. 7-11
Author(s):  
Vivi Linda Fristianti ◽  
Nur Hidayat ◽  
Slamet Iskandar
Keyword(s):  
Elementary School ◽  
Ground Water ◽  
School Children ◽  
Laboratory Data ◽  
Simple Random Sampling ◽  
Optimal Level ◽  
The Body ◽  
Design Data ◽  
Cross Sectional ◽  
Fe Content

Background : IDD problem is a serious problem, 33% of districts in Indonesia are endemic, 21% of endemic mild, moderate endemic 5% and 7% by weight endemic. Urine Iodine Excretion (EYU) illustrates the iodine intake of a person, because 90% of the iodine that enter the body are excreted through the urine. Blocking agents are substances certain minerals such as iron, manganese and calcium, which can bind iodine in groundwater. Objectives : This study aims to determine the relationship of Fe content in ground water sources against EYU levels in school children in the village of the District Cerme Panjatan Kulon Progo. Methods : An observational analytic research with cross sectional design. Data collection is done in May - June 2015. Location research Elementary School Cerme, District Panjatan Kulon Progo. The subjects of the study as many as 34 children in elementary school classroom Cerme 3, 4 and 5 were taken by simple random sampling. Well water and urine samples taken students then tested the iron in the Central Health Laboratory test Yogyakarta and iodine in urine in Magelang BP2GAKY Laboratory. Data analysis using Spearman Range test with significancy level : 0.05. Result : Fe content in the ground water is below the normal threshold is <0.3 mg / L. While levels EYU school children who are under the optimal level of 5.9%, the optimal level of 32.4%, and the optimum levels above 61.8% (optimal: 100 - 199μg / L). Conclusion : There was no significant relationship between the Fe content in groundwater with levels of EYU in school children in District Panjatan Kulon Progo (p = 0.447).   Keywords: Fe, EYU

Perbedaan Penggunaan Antikoagulan K2EDTA DAN K3EDTA Terhadap Hasil Pemeriksaan Indeks Eritrosit

2018 ◽  
Vol 1 (2) ◽  
pp. 114
Author(s):  
Wahdaniah Wahdaniah ◽  
Sri Tumpuk
Keyword(s):  
Screening Test ◽  
Venous Blood ◽  
The Body ◽  
Ethylene Diamine ◽  
P Value ◽  
Cross Sectional ◽  
Significant Difference ◽  
Ethylene Diamine Tetra Acetate ◽  
The Difference ◽  
Index Value

Abstract: Routine blood examination is the earliest blood test or screening test to determine the diagnosis of an abnormality. Blood easily froze if it is outside the body and can be prevented by the addition of anticoagulants, one of which Ethylene Diamine Tetra Acetate (EDTA). Currently available vacuum tubes containing EDTA anticoagulants in the form of K2EDTA and K3EDTA. K3EDTA is usually a salt that has better stability than other EDTA salts because it shows a pH approaching a blood pH of about 6.4. The purpose of this research is to know the difference of erythrocyte index results include MCH, MCV and MCHC using K3EDTA anticoagulant with K2EDTA. This research is a cross sectional design. This study used venous blood samples mixed with K2EDTA anticoagulant and venous blood mixed with K3EDTA anticoagulants, each of 30 samples. Data were collected and analyzed using paired different test. Based on data analysis that has been done on MCH examination, p value <0,05 then there is a significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value. Then on the examination of MCV and MCHC obtained p value <0.05 then there is no significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value.Abstrak: Pemeriksaan darah rutin merupakan pemeriksaan darah yang paling awal atau screening test untuk mengetahui diagnosis suatu kelainan. Darah mudah membeku jika berada diluar tubuh dan bisa dicegah dengan penambahan antikoagulan, salah satunya Ethylene Diamine Tetra Acetate (EDTA). Dewasa ini telah tersedia tabung vakum yang sudah berisi antikoagulan EDTA dalam bentuk  K2EDTA dan  K3EDTA. K3EDTA  biasanya berupa garam yang mempunyai stabilitas yang lebih baik dari garam EDTA yang lain karena menunjukkan pH yang mendekati pH darah yaitu sekitar 6,4. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan hasil indeks eritrosit meliputi MCH, MCV dan MCHC menggunakan antikoagulan K3EDTA dengan K2EDTA. Penelitian ini merupakan penelitian dengan desain cross sectional. Penelitian ini menggunakan sampel darah vena yang dicampur dengan antikoagulan K2EDTA dan darah vena yang dicampur dengan antikoagulan K3EDTA, masing-masing sebanyak 30 sampel. Data dikumpulkan dan dianalisis menggunakan uji beda berpasangan. Berdasarkan analisis data yang telah dilakukan pada pemeriksaan MCH didapatkan nilai p < 0,05 maka ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit. Kemudian pada pemeriksaan MCV dan MCHC didapatkan nilai p < 0,05 maka tidak ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit.

Pediatric Cataract Surgery: Comparison between Ages at Surgery and Contrast Sensitivity Outcomes

2019 ◽  
Vol 43 (1) ◽  
pp. 50
Author(s):  
Aquirina Caesari Putri ◽  
Rozalina Loebis
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Contrast Sensitivity ◽  
Cataract Extraction ◽  
Significant Negative Correlation ◽  
Natural World ◽  
P Value ◽  
Pediatric Cataract ◽  
Low Contrast ◽  
Significant Difference

Background: Pediatric cataracts are major causes of children’s blindness. Surgery has proven to be beneficial in terms of visual function prognosis. Contrast sensitivity evaluation after surgery is as important as visual acuity considering that natural world consists of various objects in low-to-medium contrasts. The purpose of this study is to analyze the difference of contrast sensitivity outcomes based on ages at surgery. Method: Retrospective data of children with pediatric developmental cataract from July 2013 to November 2015 were collected. All children who underwent cataract surgery at 60-months-old or less were randomized into two groups, ≤24 months and >24-to-60 months. Contrast sensitivity was then examined with preferential-looking method using Hiding Heidi low-contrast test face chart. The main outcome measures were contrast sensitivity of both groups. Age-at-evaluation, cataract onset, duration of follow-up, duration of deprivation and visual acuity were also noted. Result: Of 14 children (23 eyes), 11 eyes (47,8%) were in ≤24 months group, 12eyes (52,2%) were in >24-to-60 months group. All eyes underwent cataract extraction and similar type of intraocular lens implantation. Mean age-at-surgery was 28,2 months±16,8 (SD). Mean contrast sensitivity for each group was 47,50 %±42,29 and 18,33%±27,38, respectively, with p-value 0,031. Further analysis of Spearman’s correlation test demonstrated significant negative correlation (rs = -0,559; p = 0,006) between the two groups. Conclusion: There was statistically significant difference in contrast sensitivity between those who underwent surgery at ≤24 months and >24-to-60 months. Children who underwent surgery at older ages tend to have better contrast sensitivity afterwards.

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