scholarly journals PERBANDINGAN UJI RESISTENSI BAKTERI STAPHYLOCOCCUS AUREUS TERHADAP OBAT ANTIBIOTIK AMPISILIN DAN TETRASIKLIN

2015 ◽  
Vol 3 (1) ◽  
pp. 25-33
Author(s):  
Finnie Luthfia Suheri ◽  
Zulkarnain Agus ◽  
Ivony Fitria
Keyword(s):  
Staphylococcus Aureus ◽  
Immune Response ◽  
Oral Cavity ◽  
Broad Spectrum ◽  
Inhibition Zone ◽  
Total Sample ◽  
Predisposing Factors ◽  
T Test ◽  
The Body ◽  
Normal Flora

Staphylococcus aureus is one of the normal flora in the oral cavity, but these bacteria can change to be pathogen if there are predisposing factors such as changes in quantities of bacteria and decreasing of the immune response of the body. One of the ways to prevent is to inhibit the activity of these bacteria using antibiotics. Ampicillin and tetracycline are the broad-spectrum antibiotics that can inhibit the growth of positive and negative gram bacteria. This research was a laboratory experimental with Kirby-Bauer method and using CLSI standard. Total sample are 16 discs of ampicillin and 16 discs of tetracycline then placed on MHA media contain Staphylococcus aureus to see the inhibition power. The result showed that the averages of inhibition zone of ampicillin is 36,64 mm while tetracycline is 25,58 mm. Independent sample t- test showed that p<0,01 which means there is a significantly difference between ampicillin and tetracycline. Ampicillin and tetracycline can inhibit the growth of Staphylococcus aureus with sensitive categories. Ampicillin is more sensitive and effective than tetracycline to inhibit the growth of Staphylococcus aureus

scholarly journals POTENSI MADU SEBAGAI TERAPI TOPIKAL OTITIS EKSTERNA

2019 ◽  
Vol 8 (2) ◽  
pp. 7-22
Author(s):  
Yunis Sucipta Ibnu ◽  
Keyword(s):  
Inflammatory Cytokines ◽  
Broad Spectrum ◽  
Otitis Externa ◽  
Humid Tropics ◽  
Bacterial Activity ◽  
Predisposing Factors ◽  
Normal Flora ◽  
Pathogenic Microbes ◽  
Alternative Choice ◽  
Choice Of Therapy

Otitis externa (OE) is an external microbial Meatus acousticus (MAE) infection due to damage to the normal MAE serumen skin coat that protects and maintains MAE moisture and temperature. Living in the warm and humid tropics, a decrease in skin pH due to activity in the water including swimming, and excess cerumen cleaning are predisposing factors for OE. The use of antibiotics locally concentrated in OE can not only attack pathogenic microbes but also have an impact on normal flora so that it has the potential to cause resistant microbes. Honey has anti-bacterial properties without the risk of resistance and has even been shown to modulate immunity and inflammation. Various invivo and invitro studies prove that honey has broad spectrum anti-bacterial activity. Honey is proven invitro to modulate immunity by affecting the release of various inflammatory cytokines. This shows that honey has the potential for OE therapy. This article aims to discuss the potential of honey as a topical OE therapy in the hope that it can be an alternative choice of therapy in the management of OE in humans that is safe, effective, and efficient.

scholarly journals Effects of physical activity on anthropometric variables and functional capacity of patients with type 2 diabetes

2020 ◽  
pp. 1-7
Author(s):  
Robson Bonoto Teixeira ◽  
Luciana Moreira Lima ◽  
Yuri Lucas Xavier ◽  
Carlos Gabriel de Lade ◽  
Gabriela Fernandes Lopes ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Physical Exercise ◽  
Total Sample ◽  
Overweight And Obesity ◽  
T Test ◽  
The Body ◽  
Abdominal Circumference ◽  
Diabetic Patients ◽  
Significant Difference

Introduction: Type 2 Diabetes Mellitus affects current society, and is associated with overweight and obesity. Physical exercise has been showing favorable results in the anthropometric parameters and in the gain of joint flexibility and body mobility in these individuals. Objective: The objective of this study was to analyze the interference of an exercise program in anthropometric measures, flexibility and body mobility in type 2 diabetics. Method: This is a longitudinal study, performed with 14 type 2 diabetic patients, with a mean age of 55± 9 years, both genders, separated in aerobic group (n=8) and resistance group (n=6). The body mass index, waist circumference, abdominal circumference, hip circumference, waist-hip ratio, fat percentage, limp-femoral flexibility and body mobility were assessed before and after a 10-week period of aerobic or resistance exercises with a weekly frequency of 3 days. Results: For the analysis of the results, it was applied the paired t test (pre x post exercise) and independent t test (aerobic group x resistance group) with significance level of 5%. No significant differences were found in the anthropometric variables in both groups after the 10-week period of supervised training. In relation to the body mobility test, we observed a significant difference in the total sample (p=0.02), in the aerobic group (p=0.02) and in the resistance group (p=0.04). The coxofemoral flexibility test showed significant improvement (p=0.02) in the total sample and clinical improvement in aerobic (p=0.12) and resistance (p=0.09) groups. Conclusion: Both aerobic and resistance training provided positive effects in the coxofemoral flexibility and body mobility tests. In contrast, there was no significant improvement in anthropometric variables after 10 weeks of physical exercise.

scholarly journals Evaluation of Antibacterial Potential of Carbonated Hydroxyapatite Combined with Propolis on Porphyromonas gingivalis

2020 ◽  
Vol 25 (1) ◽  
pp. 55
Author(s):  
Nungky Devitaningtyas ◽  
Ahmad Syaify ◽  
Dahlia Herawati ◽  
Suryono Suryono
Keyword(s):  
Oral Cavity ◽  
Porphyromonas Gingivalis ◽  
Antibacterial Effect ◽  
Inhibition Zone ◽  
Caffeic Acid Phenethyl Ester ◽  
The Body ◽  
Graft Material ◽  
Zone Of Inhibition ◽  
Carbonated Hydroxyapatite ◽  
Significant Difference

Carbonated hydroxyapatite is ideal as a bone graft material because it has similar organic matters to the bone, excellent osteoconductive properties, and good biodegradation in the body. Hydroxyapatite contains the risk of being contaminated by bacteria called Porphyromonas gingivalis (P. gingivalis) in the oral cavity because it has no vascularization, therefore, facilitating adhesion of bacteria, and when applied in the oral cavity, it may cause an infection that then inhibits healing. Thus, it is necessary to use a material that has an antibacterial effect with low potential of causing resistance to treat the postsurgical infection properly. Propolis has antibacterial, antiviral, antifungal, antitumor, and immunomodulatory activities. Propolis contains a large number of flavonoids and phenols. The phenol compound in propolis is usually called caffeic acid phenethyl ester (CAPE), and it has a good antibacterial property. The study aims to evaluate the antibacterial effect of carbonated hydroxyapatite when immersed with different propolis concentrations of 2.5%, 5%, 7.5%, and 10% for 24 h and to measure the zone of inhibition against P. gingivalis. The Kruskal–Wallis test resulted in p = 0.00 (p < 0.05), indicating that there were significant differences among the test groups. The data processing was followed by Mann–Whitney U-test, and the results showed a significant difference in the group of carbonated hydroxyapatite-10 % propolis compared with the other groups. Inhibition zone of carbonated hydroxyapatite that immersed with propolis 10% showed the largest mean of diameters zone of inhibition.

scholarly journals Aktivitas Antibakteri Ekstrak Daun Widuri Terhadap Escherichia Coli Dan Staphylococcus Aureus

2020 ◽  
Vol 2 (1) ◽  
pp. 1-9
Author(s):  
Siti Zamilatul Azkiyah
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacterial Infections ◽  
Leaf Extract ◽  
Antibacterial Properties ◽  
Ethanol Extract ◽  
Inhibition Zone ◽  
The Body ◽  
And Staphylococcus Aureus

Antibiotics have a very important role in fighting bacterial infections in the body. However, the results given so far have not been optimal in overcoming the problem of bacterial infection. An alternative solution is to develop and study plants that have medicinal potential, for example thistle leaves (Calotrophis gigantean). The purpose of this study was to determine the antibacterial activity of thistle leaf extract against Escherichia coli and Staphylococcus aureus. This research is a laboratory-scale experimental research that is to test the activity of thistle leaf extract against Escherichia coli and Staphylococcus aureus including sample identification, extraction, activity testing by observing the inhibition zone of the two tested bacteria. Based on the results of the study stated that the ethanol extract of 70% Widuri leaves (Calotrophis gigantea) had antibacterial activity and could inhibit the growth of Escherichia coli and Staphylococcus aureus bacteria. The active compounds that are thought to have antibacterial properties in the ethanol extract of Widuri leaves (Calotrophis gigantea) are flavonoids, alkaloids and terpenoids.   Keywords: Widuri leaves, Escherichia coli, Staphylococcus aureus, Antibacterial ABSTRAK   Pentingnya penanggulangan infeksi bakteri menggunakan antibiotik adalah hal yang lazim dalam terapi farmakologi. Dampak dari pemberian antibiotik masih belum maksimal dalam penanggulangannya terhadap infeksi bakteri. Pemilihan alternatif bahan alam dengan kandungan kimia yang memiliki potensi sebagai antibiotik dapat menjadi pilihan lain dalam mengurangi penggunaan antibiotik sintetik, misalnya tanaman widuri (Calotrophis gigantean). Tujuan dari penelitian ini yaitu untuk mengetahui aktivitas antibakteri ekstrak daun widuri terhadap Escherichia coli dan Staphylococcus aureus. Desain penelitian meliputi identifikasi sampel, ekstraksi, hingga uji aktivitas dengan mengamati zona hambat dari kedua bakteri uji. Hasil penelitian menunjukkan bahwa ekstrak etanol 70% daun Widuri memiliki aktivitas antibakteri dan dapat menghambat pertumbuhan bakteri Escherichia coli dan Staphylococcus aureus. Senyawa aktif yang diduga bersifat antibakteri pada ekstrak etanol daun Widuri adalah senyawa golongan flavonoid, alkaloid dan terpenoid. Kata Kunci: Daun Widuri, Escherichia coli, Staphylococcus aureus, Antibakteri

scholarly journals Sensitivity of Propionibacterium acnes towards Commercial Anti-Acne Formulations

2021 ◽  
pp. 295-304
Author(s):  
Chandan Shivamallu ◽  
Safa Sharif ◽  
Gayatri Vidya ◽  
Chandan Dharmashekar ◽  
Bhargav Shreevatsa ◽  
...  
Keyword(s):  
Immune Response ◽  
Propionibacterium Acnes ◽  
Inhibition Zone ◽  
Normal Flora ◽  
Over The Counter ◽  
Inflammatory Lesions ◽  
Diffusion Technique ◽  
Biochemical Studies ◽  
Form Part ◽  
Gel Formulations

Propionibacterium acnes are aerotolerant anaerobic, gram-positive bacilli that form part of normal flora. They produce several pro-inflammatory substances that can trigger an immune response in the host by an influx of inflammatory leukocytes into the strands, causing inflammatory lesions that leave behind scars. Repeated isolation of Propionibacterium acnes may reduce efficacy among the resistant types, clearly explaining Acne lesions' importance. The Counter acne therapies are often the first treatment choice due to the convenience of cost and time over clinical appointments. However, not all of the commercially available anti-acne formulations are supported by clinical studies. The present study was conducted to test the efficacy of selected commercial anti-acne gel formulations. The microscopic observation and biochemical studies conform to the presence of anti-acne activity. A sensitivity test was performed on all the isolates of Propionibacterium acnes by well diffusion technique. The selected over-the-counter anti-acne gel formulations failed to produce any inhibition zone.

scholarly journals Laporan Kasus: Kandidiasis Akut Eritematous pada Penderita Diabetes Melitus

2018 ◽  
Vol 15 (1) ◽  
pp. 21
Author(s):  
Aris Aji Kurniawan ◽  
Tirta Wardana ◽  
Arif Rachman Darmawan
Keyword(s):  
Diabetes Mellitus ◽  
Oral Cavity ◽  
Oral Candidiasis ◽  
Predisposing Factors ◽  
The Body ◽  
Control Blood Glucose ◽  
Glucose Levels ◽  
Dental Hospital ◽  
Patients With Diabetes ◽  
High Level

Oral Candidiasis is infectious that caused by fungi Candida albican. Candida infection can happen on Diabetes mellitus patients (DM) because of glucose high level on oral cavity fluid and decreasing immunity patient. The purpose was to discuss and management acute erythematous candidiasis on DM patient. A 63-year-old male patient arrives at the Dental Hospital with dorsal pain, heat and pain when eating and drinking. Pain has been felt since about 2 months ago after the patient experienced heart disease. The patient has a history of controlled diabetes mellitus, controlled hypertension, asthma and gastritis. The patient feels pain in his tongue getting worse accompanied by a burning sensation and pain when the body was unhealthy. The patient was diagnosed with acute erythematous candidiasis and treated with systemic antifungal, mouthwash and topical antiseptic for oral cavity cases and was referred to an internal medicine specialist for blood sugar control. The patient was declared cured after 36 days of treatment. Knowing the predisposing factors in this case (DM) is very important in the management of erythematous acute candidiasis therapy. Patients with diabetes mellitus must routinely control blood glucose levels, maintain oral hygiene and not worsen by adding other predisposing factors.

scholarly journals Bioactivity of Origanum oil on Staphylococcus aureus

2008 ◽  
Vol 2 (1) ◽  
pp. 51-56
Author(s):  
Adel Abed Hasony ◽  
Alaa abas Fadhil ◽  
Khulood Al-Samarrae
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Broad Spectrum ◽  
Inhibitory Concentration ◽  
Biological Activities ◽  
Antimicrobial Properties ◽  
Inhibition Zone ◽  
Origanum Vulgare ◽  
Origanum Oil ◽  
Oil Extract

The studies revealed that plants oil possesses Antimicrobial properties, the origanum oil organized by a broad spectrum of antimicrobial activity. This oil extract from the Origanum vulgare found in medeternian mountain especially in Turkey. biological activities were studied to determine the effect of origanum oil on Staphylococcus aureus the result revealed that origanum oil were significantly inhibited the growth of the selected bacteria . The study showed that origanum oil has Bactericidal of effect.The inhibition zone (Hz) was determinant by using different concentration from oil as (0.5, 0.25, 0.125)mg/ml . Minimal inhibitory concentration (MIC) of oil was estimated by using different concentration as (1/10, 1/20, 1/30, 1/40, 1/50) µg/mL, the MIC of bacteria was 1/30.

Efektivitas Aroma Terapi Lemon untuk Menangani Emesis Gravidarum

2019 ◽  
Vol 11 (4) ◽  
pp. 277-284
Author(s):  
Vitrianingsih Vitrianingsih ◽  
Sitti Khadijah
Keyword(s):  
Pregnant Women ◽  
Sampling Technique ◽  
T Test ◽  
The Body ◽  
Nausea And Vomiting ◽  
P Value ◽  
Purposive Sampling ◽  
Body Tissues ◽  
Quasi Experimental ◽  
Paired T Test

Studi memperkirakan emesis gravidarum terjadi pada 50-90% kehamilan. Mual muntah pada kehamilan memberikan dampak yang signifikan bagi tubuh dimana ibu menjadi lemah, pucat dan cairan tubuh berkurang sehingga darah menjadi kental (hemokonsentrasi). Keadaan ini dapat memperlambat peredaran darah dan berakibat pada kurangnya suplay oksigen serta makanan ke jaringan sehingga dapat membahayakan kesehatan ibu dan janin. Salah satu terapi yang aman dan dapat dilakukan untuk mengurangi keluahan mual muntah pada ibu hamil adalah pemberian aromaterapi lemon. Penelitian bertujuan untuk mengetahui efektifitas aroma terapi lemon untuk menangani emesis gravidarum. Penelitian ini menggunakan rancangan Quasi experiment  dengan  one group pre-post test design. Populasi penelitian adalah ibu hamil yang mengalami emesis gravidarum di Kecamatan Berbah, Sleman. Jumlah sampel 20 ibu hamil trimester pertama yang diambil dengan teknik purposive sampling. Pengukuran mual muntah dilakukan debelum dan setelah  pemberian aromaterapi lemon menggunakan Indeks Rhodes. Analisa data menggunakan uji Paired t-test. Hasil penelitian didapatkan rata-rata skor mual muntah sebelum pemberian aromaterapi lemon berdasarkan Indeks Rhodes pada Ibu Hamil dengan emesis gravidarum yaitu 22,1 dan terjadi penurunan skor setelah pemberian aromaterapi lemon menjadi 19,8. Ada pengaruh pemberian aromaterapi lemon dengan pengurangan mual muntah pada ibu hamil (p-value = 0.017). Berdasarkan hasil penelitian dapat disimpulkan pemberian aromaterapi lemon efektif untuk mengurangi emesis gravidarum pada ibu hamil trimester pertama.  Kata kunci: aromaterapi lemon, emesis gravidarum THE EFFECTIVENESS OF LEMON AROMATHERAPY FOR HANDLING EMESIS GRAVIDARUM   ABSTRACT Studies estimate that nausea and vomiting (emesis gravidarum) occur in 50 – 90% of pregnancies. Nausea and vomiting of pregnancy have a significant impact on the body in which it makes a mother becomes weak, pale, and decreasing body fluid so that the blood becomes thick (hemoconcentration). This situation can slow down blood circulation and inflict the lack of oxygen and food supplies to the body tissues so that it can endanger the health of the mother and fetus. One of the therapies that is safe and can be conducted to reduce nausea and vomiting of pregnancy is by giving the lemon aromatherapy treatment. The research aims to determine the effectiveness of the aroma of lemon therapy to deal with emesis gravidarum. This study applied quasi-experimental research with one group pretest-posttest design. The population of this study was pregnant women who experienced emesis gravidarum. Furthermore, samples were 20 mothers from Berbah, Sleman taken by using a purposive sampling technique. Nausea and vomiting were assessed between before and after giving lemon aromatherapy using the Rhodes Index. The data were analyzed using the paired t-test. The mean score of nausea and vomiting before giving lemon aromatherapy on mother with emesis gravidarum based on the Rhodes Index was 22.1. However, it decreased after given lemon aromatherapy treatment to 19.8. Therefore, there was an effect on giving lemon aromatherapy treatment toward the decrease of nausea and vomiting for pregnant women (p-value = 0.017). Lemon aromatherapy is effective to reduce emesis gravidarum.  Keywords: lemon aromatherapy, emesis gravidarum

The Impact of Shariah Governance and Corporate Governance on the Risk Management Practices: Evidence from Local and Foreign Islamic Banks in Malaysia

2018 ◽  
Vol 15 (2) ◽  
pp. 1-20
Author(s):  
Sabri Embi ◽  
Zurina Shafii
Keyword(s):  
Risk Management ◽  
Corporate Governance ◽  
Management Practices ◽  
Principal Component ◽  
T Test ◽  
The Body ◽  
Primary Data ◽  
Islamic Banks ◽  
Shariah Governance ◽  
The Impact

The purpose of this study is to examine the impact of Shariah governance and corporate governance (CG) on the risk management practices (RMPs) of local Islamic banks and foreign Islamic banks operating in Malaysia. The Shariah governance comprises the Shariah review (SR) and Shariah audit (SA) variables. The study also evaluates the level of RMPs, CG, SR, and SA between these two type of banks. With the aid of SPSS version 20, the items for RMPs, CG, SR, and SA were subjected to principal component analysis (PCA). From the PCA, one component or factor was extracted each for the CG, SR, and RMPs while another two factors were extracted for the SA. Primary data was collected using a self-administered survey questionnaire. The questionnaire covers four aspects ; CG, SR, SA, and RMPs. The data received from the 300 usable questionnaires were subjected to correlation and regression analyses as well as an independent t-test. The result of correlation analysis shows that all the four variables have large positive correlations with each other indicating a strong and significant relationship between them. From the regression analysis undertaken, CG, SR, and SA together explained 52.3 percent of the RMPs and CG emerged as the most influential variable that impacts the RMPs. The independent t-test carried out shows that there were significant differences in the CG and SA between the local and foreign Islamic banks. However, there were no significant differences between the two types of the bank in relation to SR and RMPs. The study has contributed to the body of knowledge and is beneficial to academicians, industry players, regulators, and other stakeholders.

The Study of Bacillus Subtils Antimicrobial Activity on Some of the Pathological Isolates

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Hussein A Kadhum ◽  
Thualfakar H Hasan2
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Bacterial Growth ◽  
Broad Spectrum ◽  
Inhibitory Activity ◽  
Bacterial Pathogens ◽  
Inhibitory Ability ◽  
Selection Of

The study involved the selection of two isolates from Bacillus subtilis to investigate their inhibitory activity against some bacterial pathogens. B sub-bacteria were found to have a broad spectrum against test bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. They were about 23-30 mm and less against Klebsiella sp. The sensitivity of some antibodies was tested on the test samples. The results showed that the inhibitory ability of bacterial growth in the test samples using B. subtilis extract was more effective than the antibiotics used.

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