scholarly journals Mare's milk as a prospective functional product

2018 ◽  
Vol 8 (11) ◽  
pp. 548 ◽  
Author(s):  
Almagul Kushugulova ◽  
Samat Kozhakhmetov ◽  
Rashida Sattybayeva ◽  
Ayaulym Nurgozhina ◽  
Arailym Ziyat ◽  
...  

Background: Food has a significant effect on the health of the body, the relationship between diet and health actualizes the importance of expanding the research of functional products. Kazakhstan has a huge potential for functional products, such as saumal, or mare's milk. Since ancient times saumal has been used as an antidote, since it has the ability to excrete toxins. Today it is used for pulmonary tuberculosis, anemia, rickets, diabetes mellitus, obesity, nerve diseases, inflammatory diseases of the stomach and intestines. Saumal is called a longevity drink.

Biomedicines ◽  
2020 ◽  
Vol 8 (12) ◽  
pp. 530
Author(s):  
Hsiuying Wang

Diabetes mellitus (DM) is an endocrinological disorder that is due to either the pancreas not producing enough insulin, or the body does not respond appropriately to insulin. There are many complications of DM such as retinopathy, nephropathy, and peripheral neuropathy. In addition to these complications, DM was reported to be associated with different cancers. In this review, we discuss the association between DM and colorectal cancer (CRC). CRC is the third most commonly diagnosed cancer worldwide that mostly affects older people, however, its incidence and mortality are rising among young people. We discuss the relationship between DM and CRC based on their common microRNA (miRNA) biomarkers. miRNAs are non-coding RNAs playing important functions in cell differentiation, development, regulation of cell cycle, and apoptosis. miRNAs can inhibit cell proliferation and induce apoptosis in CRC cells. miRNAs also can improve glucose tolerance and insulin sensitivity. Therefore, investigating the common miRNA biomarkers of both DM and CRC can shed a light on how these two diseases are correlated and more understanding of the link between these two diseases can help the prevention of both DM and CRC.


2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Juan Du ◽  
Maofeng Zhong ◽  
Dong Liu ◽  
Shufang Liang ◽  
Xiaolin Liu ◽  
...  

Traditional Chinese medicine formulates treatment according to body constitution (BC) differentiation. Different constitutions have specific metabolic characteristics and different susceptibility to certain diseases. This study aimed to assess the characteristic genes of gan-shen Yin deficiency constitution in different diseases. Fifty primary liver cancer (PLC) patients, 94 hypertension (HBP) patients, and 100 diabetes mellitus (DM) patients were enrolled and classified into gan-shen Yin deficiency group and non-gan-shen Yin deficiency group according to the body constitution questionnaire to assess the clinical manifestation of patients. The mRNA expressions of 17 genes in PLC patients with gan-shen Yin deficiency were different from those without gan-shen Yin deficiency. However, considering all patients with PLC, HBP, and DM, only MLH3 was significantly lower in gan-shen Yin deficiency group than that in non-gen-shen Yin deficiency. By ROC analysis, the relationship between MLH3 and gan-shen Yin deficiency constitution was confirmed. Treatment of MLH3 (−/− and −/+) mice with Liuweidihuang wan, classical prescriptions for Yin deficiency, partly ameliorates the body constitution of Yin deficiency in MLH3 (−/+) mice, but not in MLH3 (−/−) mice. MLH3 might be one of material bases of gan-shen Yin deficiency constitution.


2019 ◽  
Vol 7 (2) ◽  
pp. 156
Author(s):  
Retno Lian Afidah

Background: Every year an average of 9 million people suffer from Tuberculosis and about 2 million people die every year in the world. The Behavior Area is divided into attitudes and actions. Purpose: The purpose of this study was to analyze the relationship between attitude, smoking behavior, physical activity and the incidence of Diabetes Mellitus–pulmonary Tuberculosis. Method: This study was an observational analytic study using a case control matching design. The research sample is 30 case samples and 30 control samples. Results: From the results of the Chi Square analysis, it is known that there is a significant relationship that is the attitude towards pulmonary Tuberculosis disease and physical activity towards pulmonary Tuberculosis (p<0.05) and there is no significant relationship (p>0.05) between smoking behavior towards Pulmonary of Diabetes Mellitus–pulmonary Tuberculosis. Odds Ratio of this study is the attitude towards pulmonary Tuberculosis disease of 3.455 and physical activity of 9.036. Conclusion: the attitude of patients with Diabetus Mellitus towards Pulmonary Tuberculosis and physical activity of patients with Diabetus Mellitus risked the incidence of Pulmonary Tuberculosis.


2020 ◽  
Vol 40 (4) ◽  
pp. 219-224
Author(s):  
Eka Suhartika ◽  
Zainuddin Amir ◽  
Bintang Yinke Magdalena Sinaga ◽  
Putri C Eyanoer

Background: The imbalance between oxidants and antioxidants in the body can increase Malondialdehyde (MDA) in patients with pulmonary TB and type 2 DM, which causes cell damage and worsens the disease. The body has a protective mechanism from damage caused by increased MDA through enzymatic antioxidants such as SOD and vitamin E. This study aimed to examine the difference in MDA levels in the blood of pulmonary TB patients with type 2 DM, pulmonary tuberculosis without type 2 DM and healthy people in Medan, Indonesia. Methods: This was an analytical study using a case-control approach by measuring MDA levels in pulmonary TB with type 2 DM patients, pulmonary TB patients and healthy people who were treated at H. Adam Malik General Hospital, Community Health Centers, and GP’s practice in Medan for 4 months. Blood samples were taken and examined using the ELISA kit. Data were then analyzed using the Kruskal Wallis and Mann Whitney tests. Results: There were 75 patients recruited in the study in which 45 were males (60%) and 30 were females (40%). The age group found the most was 31-40 years with normal BMI (76%). The highest MDA level was found in the TB+DM group at 12.42 nmol/ml compared to the TB patients (3.75 nmol/ml) and healthy people (3.01 nmol/ml). Conclusion: There were no statistically significant differences in MDA levels although there was a difference found in the MDA levels among the three groups with MDA level in TB+DM group was shown to be the highest.


Author(s):  
M. I. Zhuravlova

Nowadays, an acute myocardial infarction is one of the leading causes of mortality among the population. The EHS-DH registry data clearly illustrate the association between the comorbidities and high mortality following acute myocardial infarction during a year period of follow up. The pronounced influence of carbohydrate metabolism disturbances on the survival of such patients has already been reported. The aim of the study was to analyze the immune inflammation relationships based on assessing calprotectin and the parameters of lipid and carbohydrate metabolism, to evaluate the presence and nature of the relationship between these parameters and carbohydrate metabolism parameters based on the study of blood glucose, insulin and insulin resistance (by the indices HOMA, QUICKI, Caro), anthropometric indicators and inflammatory indicators (monocyte and neutrophile levels). Materials and methods. The study included 64 patients (mean age 65, 31 ± 1.62 years) with acute myocardial infarction and concomitant diabetes mellitus type 2. The design of the study included the primary laboratory investigation of patients during the first day since the onset of acute myocardial infarction with the elevation of the ST segment before the initiation of thrombolytic therapy or percutaneous intervention. The direct correlation between the calprotectin concentration and the HOMA insulin resistance index (R = 0.52; p <0.05), insulinemia (R = 0.57; p <0.05), fasting glycaemia (R = 0, 59; p <0.05), as well as inverse correlation relationships between the Caro index (R = 0.68; p <0.05) and the QUICKI index (R = 0.59; p <0.05) were found out. Moreover, a direct correlation between calprotectin and triglyceride levels (R = 0.31; p <0.05), and negative correlation with high density lipoprotein (R = 0.35; p <0.05) was established as well. The level of total cholesterol and low density lipoproteins showed no significant association with the proinflammatory factor (R = 0.12; p> 0.05 and R = 0.18; p> 0.05, respectively). Conclusions. The increase in the body mass index and the activity of serum monocytes and neutrophils is associated with high concentrations of calprotectin that is accompanied by disturbances of carbohydrate homeostasis towards the growth of insulin resistance and changes of lipidograms of proatherrogenic nature.


2021 ◽  
Vol 1 (2) ◽  
pp. 41-49
Author(s):  
Anisa Putri Etika Ramadena ◽  
Sintha Fransiske Simanungkalit ◽  
A’immatul Fauziyah

Diabetes mellitus occurs, one of which is characterized by hyperglycemia that occurs due to insulin abnormalities or insulin action (Perkeni, 2015). The 2018 Riskesdas survey showed an increase in the prevalence of diabetes mellitus in people over 15 years of age. High carbohydrate intake can affect the incidence of diabetes mellitus. This is caused carbohydrates that have been broken down by the body into glucose will be circulated throughout the body and the glucose balance will be controlled by the pancreas by releasing the hormone insulin. If a insulin produced is few, the glucose level in the blood will be excess and increase the occurrence of hyperglycemia. This study aims to analyze the relationship between consumption of sweet foods, body mass index and abdominal circumference with the incidence of diabetes mellitus in adults aged 26-45 years in DKI Jakarta based on the Riskesdas 2018 analysis. The results of the bivariate test with chi square showed a relationship between consumption of sweet foods (p = 0,000), body mass index (p = 0,000) and abdominal circumference (p = 0,000) with the incidence of diabetes mellitus. It can be concluded that there is a relationship between consumption of sweet foods, body mass index and abdominal circumference with the incidence of diabetes mellitus in adults aged 26-45 years in DKI Jakarta.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Su-Jin Han ◽  
Kwang-Hak Bae ◽  
Hyo-Jin Lee ◽  
Seon-Jip Kim ◽  
Hyun-Jae Cho

Abstract Physical activity reduces the risk and mortality risk of inflammatory diseases. This study aimed to examine the relationship between regular walking and periodontitis in a Korean representative sample of adults according to socioeconomic status. Data acquired by the Sixth Korea National Health and Nutrition Examination Survey in 2014 and 2015 were used. The survey was completed by 11,921 (5,175 males; 6,746 females) participants (≥19 years). Individuals without values on periodontitis were excluded, and 9,728 participants remained. Multivariable logistic regression analysis was done using socio-demographic characteristics (age, gender, income, education), oral health-related variables (flossing, interdental brushing, community periodontal index), oral and general health status and behaviour (smoking, diabetes mellitus), and regular walking. In all models, subjects who walked regularly had significantly lower risks of periodontitis. After adjusting for age, gender, income, education, smoking, diabetes mellitus, flossing, and interdental brushing, the odds ratio for periodontitis in subjects who walked regularly was 0.793 (95% Confidence interval: 0.700–0.898). Non-regular walking groups showed similar social gradients. Risk of low socioeconomic status was not significant in the regular walking group after adjusting for age, gender, income, and education. This study found that regular walking is associated to lower prevalence of periodontitis and can attenuate the relationship between periodontitis and low socioeconomic status.


2006 ◽  
Vol 62 (4) ◽  
Author(s):  
H. Goede ◽  
Fika J. Van Rensburg

Paul’s body metaphor in 1 Corinthians 12 in literary contextThe purpose of this article is to place and describe Paul’s use of the body metaphor in 1 Corinthians 12 in its literary context. By way of introduction, the importance of a proper understanding of Paul’s use of the body metaphor is indicated. The first part of the article deals with the origin and use of the body metaphor in ancient times, thereby establishing the literary context within which Paul used the metaphor. Greek, Roman and Jewish usage is described. In the second part of the article the focus moves to Paul’s use of the metaphor within its literary context. It is concluded that the body metaphor was well-known to Greek, Roman and Jewish readers, and was thus ideally suited to Paul’s unique communication of the relationship between Christ and his church.


2021 ◽  
Vol 5 (1) ◽  
pp. 120-126
Author(s):  
Winarko Winarko ◽  
Indasah Indasah

Non-Communicable Diseases (PTM) has become a serious health problem in the community. One PTM that has received a lot of attention is Diabetes Mellitus (DM) which occurs when the body cannot produce enough of the hormone insulin or cannot use insulin effectively. The aim of this study was to analyze the relationship between family support tasks and dietary adherence in Diabetes Mellitus patients in Jayawijaya District Health Office. The type of research used is survey research with explanatory research methods. The population in this study were 145 diabetes mellitus patients treated at the Jayawijaya District Health Office. The sample of this study were patients with militus diabetes who underwent treatment at the Jayawijaya District Health Office who met the sample criteria of 58 people. The sampling technique used in this research is purposive sampling technique. Based on the results of the study there is a relationship between family duties and dietary compliance in diabetus mellitus patients using spearman correlation calculations of 0.000 < 0.05 in addition to data obtained as many as 38 (65.5% ) respondents from 43 respondents of family duties are good and obedient to the diet diabetus mellitus, while from 13 respondents with family duties are quite obtained data as many as 7 respondents (12.1%) disobedient. And from 2 respondents with family duties, less data was obtained by 2 respondents (3.4%) disobedient. Based on the results of the research, it is hoped that further communication, information, and education (IEC) will improve regarding the dietary needs of diabetes mellitus.


2021 ◽  
pp. 422-430
Author(s):  
Putri Rachma Novitasari ◽  
Baiq Maylinda Gemantari ◽  
Syarifatul Mufidah ◽  
Prita Anggraini Kartika Sari

Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.


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