scholarly journals PELUANG ZAT BIOAKTIF TANAMAN SEBAGAI ALTERNATIF IMBUHAN PAKAN ANTIBIOTIK PADA AYAM / The Opportunities of Plants Bioactive Compound as an Alternative of Antibiotic Feed additive on Chicken

2019 ◽  
Vol 38 (2) ◽  
pp. 96
Author(s):  
Tiurma - Pasaribu
Keyword(s):  
Bioactive Compounds ◽  
Feed Efficiency ◽  
Pathogenic Bacteria ◽  
Negative Impact ◽  
Raw Materials ◽  
Animal Health ◽  
Bioactive Compound ◽  
Feed Additives ◽  
Feed Additive ◽  
Bioactive Substances

<p>Bioactive compounds (phenols, tannins, flavonoids, essential oils, curcumin, saponins, phyllanthin) have the ability as an antibacterial or antifungal. Feed additives are feed raw materials that do not contain nutrients, however, it may increase productivity, quality of livestock products (meat, eggs, milk, skin, feathers), the feed efficiency and to improve animal health or resistance of disease. Feed additives that are widely used in the livestock industry include antibiotics, antioxidants, antifungals, emulsifiers, and binders. The aim of using antibiotics is to reduce the population of pathogenic microbes or disturbing microbes in the digestive tract. Antibiotics have been banned for used because it can cause resistance to pathogenic bacteria or intestinal microflora which has a negative impact on consumers. To improve feed efficiency in poultry and to produce higher quality products, healthy and safe for consumption, the antibiotic could be replaced with plant bioactive compound. The aims of this review is to describe the role of plant bioactive compounds as feed additive to replace antibiotic for chickens. Some of plant bioactive substances that can be used as feed additives include phenols, curcumin, saponins, tannins, phenols, flavonoids, alkaloids. Bioactive substances from plants have several functions including inhibiting the growth of bacteria or fungi, increasing endurance, as an adjuvant, and preventing fat oxidation. It can be concluded that bioactive substances from plants have potential as feed additives which have the ability as antibacterial, antifungal, antioxidant, immunostimulator, and adjuvant.</p><p>Keywords: bioactive compound, plants, feed additives, chicken </p><p> </p><p><strong>Abstrak</strong></p><p> Zat bioaktif (fenol, tanin, flavonoid, minyak atsiri, curcumin, saponin, phyllanthin) memiliki kemampuan sebagai antibakteri atau antifungi. Imbuhan pakan adalah bahan baku pakan yang tidak mengandung nutrisi, namun dapat meningkatkan produktivitas, kualitas produk ternak (daging, telur, susu, kulit, bulu), efisiensi penggunaan pakan dan meningkatkan kesehatan hewan atau ketahanan terhadap penyakit. Imbuhan pakan yang banyak digunakan dalam industri peternakan termasuk antibiotik, antioksidan, antifungi, pengemulsi, dan pengikat (binder). Tujuan penggunaan antibiotik adalah untuk mengurangi populasi mikroba patogen atau mikroba yang mengganggu di saluran pencernaan. Antibiotik telah dilarang untuk digunakan karena dapat menyebabkan resistensi terhadap bakteri patogen atau mikroflora usus yang memiliki dampak negatif pada konsumen. Untuk meningkatkan efisiensi pakan pada unggas dan menghasilkan produk berkualitas tinggi, sehat dan aman untuk dikonsumsi, antibiotik dapat diganti dengan zat bioaktif tanaman. Tujuan dari ulasan ini adalah untuk menggambarkan peran zat bioaktif tanaman sebagai pengganti imbuhan pakan antibiotik pada ayam. Beberapa zat bioaktif tanaman yang dapat digunakan sebagai imbuhan pakan termasuk fenol, kurkumin, saponin, tanin, fenol, flavonoid, alkaloid. Zat bioaktif dari tanaman memiliki beberapa fungsi antara lain menghambat pertumbuhan bakteri atau jamur, meningkatkan daya tahan tubuh, sebagai bahan adjuvan dan mencegah oksidasi lemak. Dapat disimpulkan bahwa zat bioaktif dari tanaman berpotensi sebagai imbuhan pakan yang memiliki kemampuan sebagai antibakteri, antifungi, antioksidan, imunostimulator, dan adjuvant.</p><p>Kata kunci: Zat bioaktif, tanaman, imbuhan pakan, ayam </p>

TOXICOLOGICAL AND BIOLOGICAL SAFETY OF ANIMAL PRODUCTS

2021 ◽  
Vol 1 (3) ◽  
pp. 244-248
Author(s):  
V.I. Dorozhkin ◽  
Keyword(s):  
Negative Impact ◽  
Raw Materials ◽  
Animal Health ◽  
Food Products ◽  
Federal State ◽  
Negative Effects ◽  
Animal Products ◽  
Biological Safety ◽  
Livestock Products ◽  
State Registration

The article presents materials on the toxicological and biological safety of livestock products: contaminants of various natures that contaminate raw materials and food products (microorganisms, viruses, mycotoxins, parasites, heavy metals, etc.) are presented. To ensure biological and toxicological safety of livestock products and public health, the implementation of legislation, as well as decisions of the President of the Russian Federation, it is proposed to provide the development of a national innovative system for protecting animal health from the negative effects of pathogens and toxicants, including: conducting research on the development of fundamental foundations for the protection of animal health from the negative impact of ecotoxicants and veterinary and sanitary welfare, improvement of regulatory and legislative documents on the organization of quality control and safety of raw materials and food products; restoration of the procedure for state registration of diagnostic test systems, disinfectants, insectoacaricides and rodenticides; creation of the State Veterinary Pharmacological and Biological «State Veterinary Pharmaceutical Commission». For the implementation of these measures, provide federal state budgetary funding.

scholarly journals The Chemical Fermentation Process Properties, Bioactive Compounds, and Health Benefits of Fruit Vinegars in Pilot-Scale in Thailand

2021 ◽  
Vol 18 (4) ◽  
Author(s):  
Wilawan BOONSUPA
Keyword(s):  
Acetic Acid ◽  
Bioactive Compounds ◽  
Fermentation Process ◽  
Raw Materials ◽  
Health Benefits ◽  
Liquid Product ◽  
Chemical Properties ◽  
Bioactive Compound ◽  
Pilot Scale ◽  
Total Phenolic

Vinegar is a liquid product produced from alcoholic and acetous fermentation. Vinegar contains acetic acid and bioactive compounds, which are brewed by liquid-state and solid-state fermentation techniques. This study reviews chemical fermentation process properties, bioactive compounds, and health benefits of fruit vinegars in Thailand. Chemical properties are the alcohol percentage and acetic acid percentage of vinegar. Bioactive compounds include antioxidant activity and total phenolic content, which have the role of antioxidative activity, blood pressure and glucose control, and anti-tumor. However, further studies are needed to find the new fruit raw materials to produce fruit vinegar which have more bioactive compound and more good taste.

scholarly journals Bioactive Compounds of Seaweed Sargassum plagyophyllum and Eucheuma cottonii as Lightening Raw Materials

2017 ◽  
Vol 20 (3) ◽  
pp. 632 ◽  
Author(s):  
Maretty Twentyna Dolorosa ◽  
N. Nurjanah ◽  
Sri Purwaningsih ◽  
Effionora Anwar ◽  
Taufik Hidayat
Keyword(s):  
Heavy Metal ◽  
Vitamin C ◽  
Moisture Content ◽  
Bioactive Compounds ◽  
Raw Materials ◽  
Brown Seaweed ◽  
Chemical Characterization ◽  
Bioactive Compound ◽  
Plate Count ◽  
Phytochemical Compounds

Seaweed is main commodity with abundant amount of Indonesian waters. Seaweed contains naturally bioactive compounds that acts as antioxidant and tyrosinase inhibitor which inhibit melanin formation and the latest approach used to skin lightening. The aim of this research were to determine chemical characterization such as heavy metal, secondary metabolite (phytochemical compounds), moisture, vitamin C and E, antioxidant activity and total plate count (TPC) on dry simplisia and slurry of S. plagyophyllum and E. cottonii. Total microbe of S. plagyophyllum amounted 2,3×102 colony⁄g with moisture content 16,71% and E. cottonii amounted 2,2×103 colony⁄g with moisture content 19,79%. Brown seaweed, S. plagyophyllum, did not contain dangerous heavy metal. Vitamin C value in both spesies of seaweed were 212,95 mg/kg for<br />S. plagyophyllum and 15,95 mg/kg for E. cottonii. Vitamin E of S. plagyophyllum amounted 363,86 mg/kg and 0,23 mg/kg for E. cottonii. IC50  value of S. plagyophyllum was 109 ppm and 130,62 ppm for E. cottonii. S. plagyophyllum slurry contain bioactive compound such as alkaloids, steroids, flavonoids, saponins and tannins. E. cottonii slurry contain bioactive compound alkaloids and terpenoids.<br /><br />

scholarly journals PSVII-14 Performance and health responses of feedlot cattle consuming different feed additives during a 45-day receiving period

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 295-296
Author(s):  
Eduardo Colombo ◽  
Reinaldo F Cooke ◽  
Alice Brandão ◽  
Jacob Wiegand ◽  
Kelsey Schubach ◽  
...  
Keyword(s):  
Body Weight ◽  
Respiratory Disease ◽  
Feed Intake ◽  
Feed Efficiency ◽  
Treatment Effects ◽  
Animal Health ◽  
Feedlot Cattle ◽  
Feed Additives ◽  
Total Incidence ◽  
To Receive

Abstract This experiment compared performance and health responses of feedlot cattle consuming different feed additives during a 45-d receiving period. Angus-influenced steers (n = 256) were purchased from a commercial auction yard, and road-transported (12 h) to the experimental feedyard on d -1. Upon arrival, body weight (BW) was recorded and steers were ranked by BW into 1 or 18 drylot pens (14 or 15 steers/pen). Pens were randomly assigned to receive RAMP® from d 0 to d 45 with the inclusion of: 1) Rumensin + Tylan (Elanco Animal Health; Greenfield, IN; 360 mg and 90 mg per animal/daily, respectively; RT), 2) Rumensin + Celmanax + Certillus (Church and Dwight Co., Inc., Princeton, NJ; 18 g and 28 per animal/daily, respectively; RCC), or Celmanax + Certillus (18 g and 28 per animal/daily, respectively; CC). Feed intake during the initial 21 d of the experiment was greater (P ≤ 0.05) in CC vs. RCC and RT. No treatment effects were detected for steer BW gain and feed efficiency (P ≥ 0.41). Total incidence of steers treated for respiratory disease did not differ between treatments (77.9, 82.3, and 80.0%, respectively, P = 0.77). Removal of steers from the experiment due to extreme morbidity of mortality was greater (P = 0.02) in RT vs. CC, and intermediate for RCC (22.4, 7.0, and 12.9%, respectively). Accordingly, total liveweight per pen on d 45 was greater (P ≤ 0.05) for CC and RCC vs. RT (3.79, 3.61, and 3.20 ton, respectively). Inclusion of CC into a receiving diet improved initial feed intake compared with ionophore-containing diets, but without changing steer performance. Moreover, CC and RCC resulted in improved health responses during the 45-d receiving period compared with the traditional RT receiving diet. These results suggest that CC ingredients improved intake and immunocompetence of receiving cattle.

scholarly journals Feed Additive of Binder Seaweed Grass in Fish Feed Formulation on Physical Characteristics and Efficiency

2021 ◽  
Vol 04 (01) ◽  
Author(s):  
Kiki Haetami ◽  
Keyword(s):  
Feed Efficiency ◽  
Feed Additives ◽  
Feed Additive ◽  
Fish Feed ◽  
Durability Test ◽  
Feed Formulation ◽  
Speed Test ◽  
Randomized Design ◽  
Significant Difference ◽  
Rupture Speed

The study was designed experimentally using a Completely Randomized Design, five treatments were repeated three times included the use of carboxymethyl cellulose as a control as much as 5%, and the treatment of feed additives of seaweed as much as 5%, 75%, 10% and 12.5%. The parameters measured were feed efficiency, rupture speed test, sink speed test, durability test, stability test and moisture content test using Analysis of Variance and continued with Duncan's Multiple Distance Test. The results showed that seaweed binder additive feed increased (p <0.05) durability and stability in water, but did not show a significant difference (p> 0.05) on feed efficiency, breaking speed and sinking speed. Stability of pellets in water with the addition of seaweed binders of 10% is significantly higher (p <0.05) than other pellets, i.e. after 10 - 60 minutes ranging from 82.70% -97.40% with pellet durability of 98.24% and feed efficiency of 42.93%.

scholarly journals The use of probiotics in animal feeding for safe production and as potential alternatives to antibiotics

2021 ◽  
Vol 14 (2) ◽  
pp. 319-328
Author(s):  
Mbarga M. J. Arsène ◽  
Anyutoulou K. L. Davares ◽  
Smolyakova L. Andreevna ◽  
Ermolaev A. Vladimirovich ◽  
Bassa Z. Carime ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Pathogenic Bacteria ◽  
Current Knowledge ◽  
Fish Farming ◽  
Well Being ◽  
Feed Additives ◽  
Feed Additive ◽  
Human Consumption ◽  
Growth Promoters ◽  
Suitable Alternative

Although the production of safe food for human consumption is the primary purpose for animal rearing, the environment and well-being of the animals must also be taken into consideration. Based on microbiological point of view, the production of healthy food from animals involves considering foodborne pathogens, on the one hand and on the other hand, the methods used to fight against germs during breeding. The conventional method to control or prevent bacterial infections in farming is the use antibiotics. However, the banning of these compounds as growth promoters caused many changes in animal breeding and their use has since been limited to the treatment and prevention of bacterial infections. In this function, their importance no longer needs to be demonstrated, but unfortunately, their excessive and abusive use have led to a double problem which can have harmful consequences on consumer health: Resistance to antibiotics and the presence of antibiotic residues in food. The use of probiotics appears to be a suitable alternative to overcome these problems because of their ability to modulate the immune system and intestinal microflora, and further considering their antagonistic role against certain pathogenic bacteria and their ability to play the role of growth factor (sometimes associated with prebiotics) when used as feed additives. This review aims to highlight some of the negative effects of the use of antibiotics in animal rearing as well as emphasize the current knowledge on the use of probiotics as a feed additive, their influence on animal production and their potential utility as an alternative to conventional antibiotics, particularly in poultry, pig, and fish farming.

scholarly journals Phenotypic features and analysis of genes supporting probiotic action unravel underlying perspectives of Bacillus velezensis VTX9 as a potential feed additive for swine

2021 ◽  
Vol 71 (1) ◽  
Author(s):  
Ngoc Tung Quach ◽  
Thi Hanh Nguyen Vu ◽  
Ngoc Anh Nguyen ◽  
Van The Nguyen ◽  
Thi Lien Bui ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Genetic Basis ◽  
De Novo ◽  
Antagonistic Activity ◽  
Feed Additives ◽  
Feed Additive ◽  
Probiotic Properties ◽  
Bacillus Velezensis ◽  
Phenotypic Analysis ◽  
First Time

Abstract Purpose To date, a total of 13 probiotic Bacillus species are considered as a Generally Recognized as Safe organism (GRAS) approved by the US Federal Food, Drug, and Cosmetic Act (FDCA), which are used for food and feed additives. However, Bacillus velezensis is not considered as a probiotic candidate in swine farming due to a lack of genetic basis of probiotic action-related traits. Therefore, the present study was undertaken to exploit the genetic basis underlying the probiotic traits of B. velezensis VTX9. Methods The genome sequencing of B. velezensis VTX9 was performed on a PacBio Sequel platform. The probiotic properties including biosafety, antioxidative capacity, and riboflavin and exopolysaccharide production were evaluated by using genotypic and phenotypic analysis. The secondary metabolite potentials were also predicted. Results Strain VTX9 isolated from swine feces proved some probiotic properties including resistance to 3 mM H2O2, 0.6 mM bile salt, low pH, and antipathogenic activity. The complete genome of B. velezensis VTX9 consists of a 3,985,800 bp chromosome that housed 3736 protein-coding genes and 5 plasmids with the size ranging from 7261 to 20,007 bp. Genome analysis revealed no functional genes encoding enterotoxins and transferable antibiotic resistance, which confirmed the safety of VTX9. A total of 82 genes involved in gastrointestinal stress tolerance were predicted, which has not been reported previously. The maximum production of riboflavin reached 769 ± 7.5 ng/ml in LB medium after 72 h, which was in agreement with the complete de novo riboflavin biosynthetic pathway exploited for the first time in the B. velezensis genome. Antagonistic activity against pathogenic bacteria was attributed to 10 secondary metabolites clusters. The presence of a large gene cluster involved in biosynthesis of exopolysaccharides underscored further the adhesion and biofilm-forming capabilities of VTX9 in swine intestines. Conclusion Our results revealed for the first time that B. velezensis VTX9 has the potential to be a probiotic candidate. The information provided here on the genome of B. velezensis VTX9 opens new opportunities for using B. velezensis as a feed additive for swine farming in the future.

scholarly journals SENYAWA BIOAKTIF MIKROALGA DAN PROSPEKNYA DI MASA DEPAN

OSEANA ◽  
2019 ◽  
Vol 44 (1) ◽  
pp. 15-25
Author(s):  
Indyaswan Tegar Suryaningtyas
Keyword(s):  
Bioactive Compounds ◽  
Raw Materials ◽  
Bioactive Compound ◽  
Terrestrial Plants ◽  
Food Ingredients ◽  
Microalgae Biomass ◽  
The Right ◽  
Anti Fungal ◽  
Potential Use ◽  
Β Carotene

BIOACTIVE COMPOUND FROM MICROALGAE AND ITS FUTURE PROSPECT. Microalgae biomass is potential to be used in various fields, one of which is as a producer of bioactive compounds. Bioactive compounds from microalgae can be used extensively in the pharmaceutical industry, cosmetic’s raw materials, food flavouring substances, and functional food ingredients. In terms of health, the bioactive compounds have the potential as antioxidants, antiviral, antibacterial, anti-fungal, anti-inflammatory, anti-tumor, and prevent the effects of malaria, but the potential for microalgae’s bioactive compound has not been explored well if compared to the production of terrestrial plants. Some examples of the bioactive compounds that have been used are carotenoid groups such as lutein, β-carotene, astaxanthin and fucoxanthin; fatty acid groups such as EPA and DHA; and also some toxin compounds such as domoic acid. To obtain the optimum yield of bioactive compounds, it requires the right method in biomass production, compound extraction, compounds isolation and compounds identification. While testing the activities, it is necessary to do some assays such as antioxidan, antibiotic, antiviral and anticancer assay. The development of the technology can improve the potential use of microalgae to synthesis its bioactive compounds.

scholarly journals Herbs in a sustainable animal nutrition

2010 ◽  
Vol 26 (3-4) ◽  
pp. 203-214 ◽  
Author(s):  
D. Runjaic-Antic ◽  
S. Pavkov ◽  
J. Levic
Keyword(s):  
Animal Feed ◽  
Raw Materials ◽  
Animal Health ◽  
Developed Countries ◽  
Physiological Effect ◽  
Feed Additives ◽  
Animal Origin ◽  
Strong Trend ◽  
Antibiotic Drugs

Animal has a direct impact on the quality of meat, milk and eggs in a positive and negative sense. Over the composition of a meal for animals can manipulate the quality of products of animal origin and can be achieved by a variety of nutritional, sensory, chemical, physical and physiological characteristics. The use of medicine in intensive and extensive farming is a big and risky to the quality of food and thus health. In organic farming of animals is not allowed to use medicines. Because are increasingly looking for natural healing resources. Herbs provides, in the manufacture of animal feed, a real opportunity to increase value through the use of different functional additions. Addition food for animals, really can improve its functionality in terms of a physiological effect. In developed countries in Europe is very strong trend of replacing synthetic antibiotic drugs based on medicinal herbal preparations. As herbal feed additives may be used drug (finely divided dry medicinal herbal raw materials), herbal extracts or herbal isolate (e.g. essential oil). The paper gives a short overview of the most important potential of herbal medicinal materials with antibacterial activity, antiinflammatory, digestion-stimulating, laxative, antidiarrhoeal, choleretic etc. activities that have an approved application in human medicine and which can be added to animal feed for use in different animal health disorders. The use of herbs is more current and all higher, in human and veterinary food industry.

scholarly journals PSXIV-39 Use of flamocycin, narasin and salinomycin on performance of Nellore yearling bulls fed with high forage diets

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 433-433
Author(s):  
Arnaldo C Limede ◽  
Daniel M Polizel ◽  
Alexandre A Miszura ◽  
André S Martins ◽  
José P R Barroso ◽  
...  
Keyword(s):  
Feed Efficiency ◽  
Block Design ◽  
Bos Indicus ◽  
Experimental Period ◽  
Feed Additives ◽  
Feed Additive ◽  
Water Restriction ◽  
Delivery Vehicle ◽  
Randomized Block Design ◽  
High Forage

Abstract The aim of this study was evaluating the effects of different feed additives on performance of yearling bulls fed a high forage diet. One hundred and sixty-four Nellore (Bos indicus) yearling bulls were assigned to a complete randomized block design, according to of their initial body weight (BW) (298.95 ± 2.49; 10 pen/treatment; 4 animal/pen). Yearling bulls were fed daily and diets were composed of 96% of coastcross haylage and 4% of ground corn, used as the delivery vehicle for the additives. Once a day, the concentrate and forage were offered separately. The forage was offered after the entire consumption of the concentrate. The experimental diets consisted in: CON = Control (no feed additive); FLA = 3ppm of Flavomycin; NAR = 13ppm of Narasin; SAL = 20ppm of Salinomycin. The experimental period lasted 140 d and the yearling bulls were weighted at 0, 28, 56, 84, 112 and 140 d, after a 14h feed and water restriction. The orts were recorded to determine the dry matter intake (DMI). All data were analyzed using the MIXED procedure of SAS and the LSMEANS option was used to generate individual means. Tukey test 5% was used for comparisons. There was a treatment effect on DMI (CON: 6.59b; FLA: 6.53b; NAR: 7.1a; SAL: 6.42b kg/d; SEM = 0.19; P &lt; 0.01), ADG (CON: 0.792b; FLA: 0.842b; NAR: 0.907a; SAL: 0.813b kg; SEM = 0.02; P &lt; 0.01) and final BW (CON: 408.27b; FLA: 411.36b; NAR: 424.69a; SAL: 407.91b kg; SEM = 2.56; P &lt; 0.01). There was no effect on feed efficiency (P = 0.41). In summary, the narasin inclusion increased DMI, ADG, and final BW in comparison with the other additives.

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